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The map label for this gene is speA [H]

Identifier: 83591086

GI number: 83591086

Start: 2370301

End: 2371800

Strand: Reverse

Name: speA [H]

Synonym: Moth_2265

Alternate gene names: 83591086

Gene position: 2371800-2370301 (Counterclockwise)

Preceding gene: 83591087

Following gene: 83591084

Centisome position: 90.22

GC content: 57.2

Gene sequence:

>1500_bases
ATGCTGGACCAGACCAGGACACCGGTCTTTACGGCGATAAAACAATATATAGATGATGAGGTTATTCCCTTCCACGTGCC
CGGACACAAGCAGGGCCGGGCCCTGCCGGAGTTTAAGGAGTATGTGGGCGAACGGGTCCTGGCCATGGATTTGACCTGTG
TTCCGGGCCTGGATAATATCTGCAACCCCCGGGATGTCATCCGGGAGGCGGAGGAACTGACGGCGGCGGCCTACGGAGCG
GAACACGCTTTTTTTCTCGTCAACGGCACCACCTCCGGCATCCAGGCCATGATCCTGGCCGTCTGCCAGCCAGGGGACAA
GATTATCATTCCCCGCAACGCCCATCGCTCGGCCCTGGGGGGCCTTATCCTGAGCGGGGCCCGGCCGGTATATATTGAAC
CGGAGATCAACGCTGACTTTGGTATCTCCATGGGTATAACCCCGGAACAAGTGGAAGCGGCCTTAAGGGAACACCCGGAC
GCGAAAGCAGTCTTCGTTATCAGCCCCAATTACTACGGCACCGTCCCTCCGTTAAAGGAAATCGTTGCTATAGCCCATAG
CTATGACGTGCCGGTATTGGTCGATGAGGCCCACGGTGCCCACCTGAAGTTCCATCCGGCGCTACCTCCTTCAGCCATGG
AGGCGGGGGCGGACCTGGCGGCAACCAGTGCCCATAAGTTAGCCGGTTCCCTGACCCAGAGTTCCTATCTCCTGCTCCAG
GGGGGAAGGCTGGATCCTAAGCATATCAAAGCGGTCCTTAACCTTTCCCAGACCACCAGTCCTTCTTATATCCTCCTGGC
TTCCCTGGACGTAGCCAGAAAGCAGATGATCCTCAAGGGCCGGAAACTCTTGGAACGGACCCTGGAGATAGCCCATTGGA
TCCGCGGAGAGCTATCCCGCATCGAAGGCCTGGCCATTATGGGTGAAGAGGTTACCTCCCTGCCTGGTTGCAGTTACCTG
GACCCCACCAAGATTACTGTCAACGTCCAGGGGCTGGGGTTGTCCGGTTATGAAATGGAAACCCTTTTACGCCGGGAGTA
TAAAATCCAGGTCGAGCTCTCCGACCTCTATAACGTCCTGCTCCTGGTTTCCATAGGTGATAATGAGGAGACCGCCGGTA
AGCTGGTAGCTGCCTTTAAAGATATAGCCAGGAAGCGCTCCTTAAAGAACGTAGTCCGCTTTTGCCCGCCCTTGCCGGCC
ATTCCCCGCATGGCGGTCTTGCCCCGGGAAGCCTTTTACAGCCAGACTTATTGCCTGGAATTGGATTATGCGGAAGGAGA
AATCAGCGCCGAAGCCATTACCGCCTACCCGCCGGGTATCCCCCTGGTCTGCCCGGGAGAGGTTATTACCAGGGAGATTA
TAGATTACGTTAACCTGCTGAAAAGAGAGCATGCCGACTTGCAGGGGCCGGAAGACCCGGAACTCAAGGTTATCCGCGTC
TTGAAGGATACGGTGAGTATGCTCGAACACGGGGCGGCCAGCCGGGCCGGGCTGGCCTGA

Upstream 100 bases:

>100_bases
CGGCCGGGTTCATAAAAATGTATTGAAAAACCTTCTTGCATCCACTTGCAGTTTGTGGTGTAATAAAATCTGTTGCAAAA
CCCTACAGGGGGCGATGGTT

Downstream 100 bases:

>100_bases
ATCATGGCCCTGTAGCCGGTAGCAGGCCGAATAGGTTTACGCCTTGACATCCCCCGGCGCCGTTTCCTATACTAAAGGAA
AAGTAACAGCTTTTCTCCTG

Product: arginine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MLDQTRTPVFTAIKQYIDDEVIPFHVPGHKQGRALPEFKEYVGERVLAMDLTCVPGLDNICNPRDVIREAEELTAAAYGA
EHAFFLVNGTTSGIQAMILAVCQPGDKIIIPRNAHRSALGGLILSGARPVYIEPEINADFGISMGITPEQVEAALREHPD
AKAVFVISPNYYGTVPPLKEIVAIAHSYDVPVLVDEAHGAHLKFHPALPPSAMEAGADLAATSAHKLAGSLTQSSYLLLQ
GGRLDPKHIKAVLNLSQTTSPSYILLASLDVARKQMILKGRKLLERTLEIAHWIRGELSRIEGLAIMGEEVTSLPGCSYL
DPTKITVNVQGLGLSGYEMETLLRREYKIQVELSDLYNVLLLVSIGDNEETAGKLVAAFKDIARKRSLKNVVRFCPPLPA
IPRMAVLPREAFYSQTYCLELDYAEGEISAEAITAYPPGIPLVCPGEVITREIIDYVNLLKREHADLQGPEDPELKVIRV
LKDTVSMLEHGAASRAGLA

Sequences:

>Translated_499_residues
MLDQTRTPVFTAIKQYIDDEVIPFHVPGHKQGRALPEFKEYVGERVLAMDLTCVPGLDNICNPRDVIREAEELTAAAYGA
EHAFFLVNGTTSGIQAMILAVCQPGDKIIIPRNAHRSALGGLILSGARPVYIEPEINADFGISMGITPEQVEAALREHPD
AKAVFVISPNYYGTVPPLKEIVAIAHSYDVPVLVDEAHGAHLKFHPALPPSAMEAGADLAATSAHKLAGSLTQSSYLLLQ
GGRLDPKHIKAVLNLSQTTSPSYILLASLDVARKQMILKGRKLLERTLEIAHWIRGELSRIEGLAIMGEEVTSLPGCSYL
DPTKITVNVQGLGLSGYEMETLLRREYKIQVELSDLYNVLLLVSIGDNEETAGKLVAAFKDIARKRSLKNVVRFCPPLPA
IPRMAVLPREAFYSQTYCLELDYAEGEISAEAITAYPPGIPLVCPGEVITREIIDYVNLLKREHADLQGPEDPELKVIRV
LKDTVSMLEHGAASRAGLA
>Mature_499_residues
MLDQTRTPVFTAIKQYIDDEVIPFHVPGHKQGRALPEFKEYVGERVLAMDLTCVPGLDNICNPRDVIREAEELTAAAYGA
EHAFFLVNGTTSGIQAMILAVCQPGDKIIIPRNAHRSALGGLILSGARPVYIEPEINADFGISMGITPEQVEAALREHPD
AKAVFVISPNYYGTVPPLKEIVAIAHSYDVPVLVDEAHGAHLKFHPALPPSAMEAGADLAATSAHKLAGSLTQSSYLLLQ
GGRLDPKHIKAVLNLSQTTSPSYILLASLDVARKQMILKGRKLLERTLEIAHWIRGELSRIEGLAIMGEEVTSLPGCSYL
DPTKITVNVQGLGLSGYEMETLLRREYKIQVELSDLYNVLLLVSIGDNEETAGKLVAAFKDIARKRSLKNVVRFCPPLPA
IPRMAVLPREAFYSQTYCLELDYAEGEISAEAITAYPPGIPLVCPGEVITREIIDYVNLLKREHADLQGPEDPELKVIRV
LKDTVSMLEHGAASRAGLA

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=588, Percent_Identity=25, Blast_Score=132, Evalue=5e-32,
Organism=Escherichia coli, GI1790573, Length=553, Percent_Identity=24.5931283905967, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI221142684, Length=570, Percent_Identity=22.280701754386, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1786909, Length=608, Percent_Identity=23.8486842105263, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI87082193, Length=593, Percent_Identity=22.9342327150084, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 54458; Mature: 54458

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDQTRTPVFTAIKQYIDDEVIPFHVPGHKQGRALPEFKEYVGERVLAMDLTCVPGLDNI
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCEEEEEEEEECCCCCCC
CNPRDVIREAEELTAAAYGAEHAFFLVNGTTSGIQAMILAVCQPGDKIIIPRNAHRSALG
CCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHH
GLILSGARPVYIEPEINADFGISMGITPEQVEAALREHPDAKAVFVISPNYYGTVPPLKE
HHEECCCCCEEECCCCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
IVAIAHSYDVPVLVDEAHGAHLKFHPALPPSAMEAGADLAATSAHKLAGSLTQSSYLLLQ
HHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEE
GGRLDPKHIKAVLNLSQTTSPSYILLASLDVARKQMILKGRKLLERTLEIAHWIRGELSR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLAIMGEEVTSLPGCSYLDPTKITVNVQGLGLSGYEMETLLRREYKIQVELSDLYNVL
HCCEEEECCHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHEEEEEEHHHHCCEE
LLVSIGDNEETAGKLVAAFKDIARKRSLKNVVRFCPPLPAIPRMAVLPREAFYSQTYCLE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHCCCEEEEE
LDYAEGEISAEAITAYPPGIPLVCPGEVITREIIDYVNLLKREHADLQGPEDPELKVIRV
EECCCCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LKDTVSMLEHGAASRAGLA
HHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLDQTRTPVFTAIKQYIDDEVIPFHVPGHKQGRALPEFKEYVGERVLAMDLTCVPGLDNI
CCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHCCEEEEEEEEECCCCCCC
CNPRDVIREAEELTAAAYGAEHAFFLVNGTTSGIQAMILAVCQPGDKIIIPRNAHRSALG
CCHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHH
GLILSGARPVYIEPEINADFGISMGITPEQVEAALREHPDAKAVFVISPNYYGTVPPLKE
HHEECCCCCEEECCCCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHH
IVAIAHSYDVPVLVDEAHGAHLKFHPALPPSAMEAGADLAATSAHKLAGSLTQSSYLLLQ
HHHHHHCCCCCEEEECCCCCEEEECCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEEEEE
GGRLDPKHIKAVLNLSQTTSPSYILLASLDVARKQMILKGRKLLERTLEIAHWIRGELSR
CCCCCHHHHHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEGLAIMGEEVTSLPGCSYLDPTKITVNVQGLGLSGYEMETLLRREYKIQVELSDLYNVL
HCCEEEECCHHHCCCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHEEEEEEHHHHCCEE
LLVSIGDNEETAGKLVAAFKDIARKRSLKNVVRFCPPLPAIPRMAVLPREAFYSQTYCLE
EEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHCCCEEEEE
LDYAEGEISAEAITAYPPGIPLVCPGEVITREIIDYVNLLKREHADLQGPEDPELKVIRV
EECCCCCCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
LKDTVSMLEHGAASRAGLA
HHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]