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The map label for this gene is arsB [H]

Identifier: 83591031

GI number: 83591031

Start: 2307566

End: 2308630

Strand: Reverse

Name: arsB [H]

Synonym: Moth_2208

Alternate gene names: 83591031

Gene position: 2308630-2307566 (Counterclockwise)

Preceding gene: 83591032

Following gene: 83591028

Centisome position: 87.82

GC content: 53.9

Gene sequence:

>1065_bases
ATGGCACCAGTAAATAATTATCAACCCGTGGCCAGGTTATCCCTCCTGGATCGCTTTTTGACCCTGTGGATCTTCCTGGC
CATGGCCCTGGGCGTGGGCCTGGGTTATATGGTGCCCGGGGTAGCGGATGCTCTGAATAAAATGTCTGTGGGCACAACTT
CCATCCCCATCGCCATCGGCCTTATCGTCATGATGTACCCGCCCCTGGCCAAGGTCAAGTACGAGGAACTGGGCAAGGTA
TTCCGCAACGGCAAAGTTATGGCCTTATCCCTTATCCAGAACTGGATTATCGGTCCCATCCTGATGTTTGTCCTGGCCAT
TCTCTTTTTGCACAATTATCCGGAATACATGGCCGGCCTCATTTTAATCGGCCTGGCGCGCTGCATCGCCATGGTCATCG
TCTGGAACAGCCTGGCCCGGGGCGACGCCGAGTACGCCGCCGCCCTGGTGGCCTTGAACTCCATCTTCCAGGTTATCTTT
TATTCAATTTACGCCTATATTTTCATCACCCTGCTACCTTCCTGGCTGGGTTTTCAAGGAATGAAAGTCCACGTTTCTAT
CGGCGAGGTGGCCACCAGCGTGGCCATCTACCTGGGCATCCCCTTCCTGGCCGGGGTGTTTACCCGTTTTACCCTCATAC
CGGCCAGGGGCAAAGAATGGTATGAGAAAACCTTTGTCCCCAAAATCAGCCCCCTGGCTTTAATCGCCCTGCTATTTACT
ATTGTGGTCATGTTTTCCCTGAAAGGCCAGTATATCGTTTCGTTACCCATGGATGTAGTCAGGATCGCTGTACCCCTGAT
CTGCTACTTTGTTATTATGTTTCTCATTTCATTTTTCGTCAGCATGCGCCTGGGGGTCAACTACGAGCAAACCACGACCC
TCTCCTTTACGGCCGCCAGCAACAATTTTGAGCTGGCCATCGCCGTGGCCGTGGCCGTCTTCGGCATTAATTCCGGCCAG
GCCTTCGCAGCGGTCATCGGGCCCTTAATTGAGGTGCCAGTGATGATCGGCCTGGTGAACGTCGCCCTGGGTTTCCAGCG
GCGATATTACGGCGTAGGGGGATAG

Upstream 100 bases:

>100_bases
GGTATAAGTAAAGACGGCAACTGTTAGGGCGCGTTTATGAAAATAGGGCTATTTTCGTACTAACGTAGCAAAGAAAGGAT
AAGAAGGAGGATTTCAGTTA

Downstream 100 bases:

>100_bases
AGAAAGCTAAAAAAGTTATGAGGTCTCGGGAAATCGGAGCCTGGCTACCCCCCGGACCTGCTCCATTGAGATGTCGACCG
GGCAAAGGTCAGGCGCCGGG

Product: arsenical-resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MAPVNNYQPVARLSLLDRFLTLWIFLAMALGVGLGYMVPGVADALNKMSVGTTSIPIAIGLIVMMYPPLAKVKYEELGKV
FRNGKVMALSLIQNWIIGPILMFVLAILFLHNYPEYMAGLILIGLARCIAMVIVWNSLARGDAEYAAALVALNSIFQVIF
YSIYAYIFITLLPSWLGFQGMKVHVSIGEVATSVAIYLGIPFLAGVFTRFTLIPARGKEWYEKTFVPKISPLALIALLFT
IVVMFSLKGQYIVSLPMDVVRIAVPLICYFVIMFLISFFVSMRLGVNYEQTTTLSFTAASNNFELAIAVAVAVFGINSGQ
AFAAVIGPLIEVPVMIGLVNVALGFQRRYYGVGG

Sequences:

>Translated_354_residues
MAPVNNYQPVARLSLLDRFLTLWIFLAMALGVGLGYMVPGVADALNKMSVGTTSIPIAIGLIVMMYPPLAKVKYEELGKV
FRNGKVMALSLIQNWIIGPILMFVLAILFLHNYPEYMAGLILIGLARCIAMVIVWNSLARGDAEYAAALVALNSIFQVIF
YSIYAYIFITLLPSWLGFQGMKVHVSIGEVATSVAIYLGIPFLAGVFTRFTLIPARGKEWYEKTFVPKISPLALIALLFT
IVVMFSLKGQYIVSLPMDVVRIAVPLICYFVIMFLISFFVSMRLGVNYEQTTTLSFTAASNNFELAIAVAVAVFGINSGQ
AFAAVIGPLIEVPVMIGLVNVALGFQRRYYGVGG
>Mature_353_residues
APVNNYQPVARLSLLDRFLTLWIFLAMALGVGLGYMVPGVADALNKMSVGTTSIPIAIGLIVMMYPPLAKVKYEELGKVF
RNGKVMALSLIQNWIIGPILMFVLAILFLHNYPEYMAGLILIGLARCIAMVIVWNSLARGDAEYAAALVALNSIFQVIFY
SIYAYIFITLLPSWLGFQGMKVHVSIGEVATSVAIYLGIPFLAGVFTRFTLIPARGKEWYEKTFVPKISPLALIALLFTI
VVMFSLKGQYIVSLPMDVVRIAVPLICYFVIMFLISFFVSMRLGVNYEQTTTLSFTAASNNFELAIAVAVAVFGINSGQA
FAAVIGPLIEVPVMIGLVNVALGFQRRYYGVGG

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6325459, Length=335, Percent_Identity=36.4179104477612, Blast_Score=183, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 38774; Mature: 38643

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPVNNYQPVARLSLLDRFLTLWIFLAMALGVGLGYMVPGVADALNKMSVGTTSIPIAIG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCCCHHHHHHH
LIVMMYPPLAKVKYEELGKVFRNGKVMALSLIQNWIIGPILMFVLAILFLHNYPEYMAGL
HHHHHCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILIGLARCIAMVIVWNSLARGDAEYAAALVALNSIFQVIFYSIYAYIFITLLPSWLGFQG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MKVHVSIGEVATSVAIYLGIPFLAGVFTRFTLIPARGKEWYEKTFVPKISPLALIALLFT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
IVVMFSLKGQYIVSLPMDVVRIAVPLICYFVIMFLISFFVSMRLGVNYEQTTTLSFTAAS
HHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
NNFELAIAVAVAVFGINSGQAFAAVIGPLIEVPVMIGLVNVALGFQRRYYGVGG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
APVNNYQPVARLSLLDRFLTLWIFLAMALGVGLGYMVPGVADALNKMSVGTTSIPIAIG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHCCCCCHHHHHHH
LIVMMYPPLAKVKYEELGKVFRNGKVMALSLIQNWIIGPILMFVLAILFLHNYPEYMAGL
HHHHHCCCHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
ILIGLARCIAMVIVWNSLARGDAEYAAALVALNSIFQVIFYSIYAYIFITLLPSWLGFQG
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
MKVHVSIGEVATSVAIYLGIPFLAGVFTRFTLIPARGKEWYEKTFVPKISPLALIALLFT
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCHHHHHHHHHH
IVVMFSLKGQYIVSLPMDVVRIAVPLICYFVIMFLISFFVSMRLGVNYEQTTTLSFTAAS
HHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECC
NNFELAIAVAVAVFGINSGQAFAAVIGPLIEVPVMIGLVNVALGFQRRYYGVGG
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]