| Definition | Moorella thermoacetica ATCC 39073, complete genome. |
|---|---|
| Accession | NC_007644 |
| Length | 2,628,784 |
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The map label for this gene is pcrA [H]
Identifier: 83590844
GI number: 83590844
Start: 2099878
End: 2102067
Strand: Reverse
Name: pcrA [H]
Synonym: Moth_2014
Alternate gene names: 83590844
Gene position: 2102067-2099878 (Counterclockwise)
Preceding gene: 83590846
Following gene: 83590843
Centisome position: 79.96
GC content: 61.1
Gene sequence:
>2190_bases GTGAAGGTATTGGCAGATTTTATGGCTTTACTCAATGGTCCCCAGCAGGAGGCCGTCAAGCACCGGGGCACACCCCTCCT GGTCCTGGCCGGAGCCGGCAGCGGCAAGACCCGGGTCCTTACTTACCGGGTGGCCGCCCTGATTCAGGAAGGTGTTCGCC CGGAAAACATCCTCGCGGTTACCTTTACCAATAAAGCGGCCCAGGAAATGAAAGAACGCCTGGAGGGCCTGGTAGGGGAG GCGGCCCGGGGCCTCTGGGTCAGCACCTTCCATTCAGCCTGTGTCCGCATTCTGCGGCGGGAGGCCCACCTCCTTGGTTA TCGGCCGAATTTTGTCATCTACGATACCGACGATCAGCAGGCGGCCCTTAAAGAGGTCTTAAAAGAGTTAGACCTGGATG ATAAAAAATATCCGCCTCGTTCCCTGGCTCAGGTCATTAGCATGGCCAAGAACGACCTTAAGACACCGGAGCGTTTCCTG GACGGCGCGGCCACCTTCCGGGAGCAACAGCAGGGGCAGATTTACCGCCGTTATCAGGAGAAGCTGCGGGAATTAAACGC CATGGACTTTGACGATCTTATCATGCAAACGGTCTTTCTCTGGCAGCAGAATCCCCTGGTATTACGTTACTACCAGCAGC GCTGGCAGCATATCCTGGTGGACGAATACCAGGATACCAACCACGCCCAGTACATCCTGGTGCGTCTCCTTGCCGGTAAA GGGGACAACCTCTGTGTCGTCGGCGACCCGGATCAGGGTATCTACGGCTGGCGGGGAGCTGATATCGGTAACATACTGGC CTTTGAGGAGGACTTCCCCCGGGCCCGGGTGATTCTCCTGGAAGAAAACTACCGGTCCACCCGGCCCATCCTCCAGGCCG CCAATGCCGTTATCCAGCATAATGAGGGGCGCCGGGAGAAACGCCTCTGGACACGGCGGCGGGAAGGAGAGCTGTTGCAC CTGTACCGGGCGACTGACGAGCGGGATGAGGGGCGGTTTATCGCCGGCGAGGTTTACCGCCGGCACCAGCAGGAGGGGCG GCCCTTCAGCGACTTTGCCGTCCTCTACCGCACCCATGCCCAGTCGCGGGCCCTGGAAGAGGCCTTTATCCAGGCCGGTG TCCCCTACGAGATTGTCGGCGGCCTGAAGTTCTACCAGCGCAAGGAGATTAAGGATATCCTGGCCTATCTGCGGGTAATT GCCAACCCGGACGATAGCCTCAGCCTGTTGCGGATTATCAACGTCCCCCGGCGGGGTATCGGCGAGGCCACCCTGGCCAG GCTGGAAGCCGCCGCTACCAGTGAGGGGGAGAGCCTTTACCGGGTCCTGGAGCGGGTGGACACCATCCCCGGCATCCCGG CCCGGGGCCGGCAGGCACTGCGGGAACTGGTGGAAATGCTGGATAACCTTCGCCAGCAGCAGGAAAAAATAACGGTGACG GACCTGGTGGCTACCATCTTGCAAGAGACGGGTTATCAAGCAGAACTGGAGGCGGAGCGGACTCCTGAGGCCCAGGCCCG GCTGGAGAACTTGAAGGAATTCCAGACGGTGACCCGGAGCTACGACCAGGGGGCTCCGGAATCATCCCTGGGAGATTTCC TGACCCAGGTAGCCCTGGTGGCGGAGAGTGACACCTATAGCGGCAATGCCGCGGTGGCCTTAATGACCATGCATACGGCC AAGGGACTGGAATTCCCGGTGGTCTTCCTGGCCGGCCTAGAAGAGGGGGTTTTCCCCCATTTTCGCTCCCTGGACGACCC GGCGGAGATGGAAGAAGAACGGCGACTCTGCTATGTGGGCATGACCAGGGCCAGGGAGGTCCTGTATCTCACCCATGCCT GGACGCGTAACCTTTACGGTAGCACCATGAGCAATCCTCCCTCCCGGTTTCTGGATGAGATACCGGCCGACTTGATCCAG GGCGAAGGAACCGGCCTGCGGTCCGGGGTCCTTAGCCGGACCAGTGAGGAACGGGATGACCGGGGCCGATCAACCCGGCG CCAGCCGGCACCGGCAAGGAGCACCCGGGCCTCCTGGCAGGTGGGGGACAAGGTCCAGCATGACGCCTGGGGCCTGGGCG TCATAGTAAAGATCAGCGGCGAAGGCGATGATGCCATCATCAGCGTCGCCTTTCCCGGGCGGGGCATCAAGCAACTGGCC CTCCGCTACGCCCCGATTAGGAAGGCTTAA
Upstream 100 bases:
>100_bases TGCTGCATTATATGCATTACCTTCCTGGAAGGGGAAAAAGAAGGCCGTTTCCTTGCAGGTTTTTTGGCTGCCGGGGCGAA TATAACCAGGGCTTAGGAGT
Downstream 100 bases:
>100_bases GTACGCGTAACCCTATGGGAGCTCTTTATGGAGACGCGCCGCTGCTATCCTGGGAAGTTCAGTTTTCAGGAGTTGGCAGA GAGCCGTTGGGTAACTATTT
Product: ATP-dependent DNA helicase PcrA
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 729; Mature: 729
Protein sequence:
>729_residues MKVLADFMALLNGPQQEAVKHRGTPLLVLAGAGSGKTRVLTYRVAALIQEGVRPENILAVTFTNKAAQEMKERLEGLVGE AARGLWVSTFHSACVRILRREAHLLGYRPNFVIYDTDDQQAALKEVLKELDLDDKKYPPRSLAQVISMAKNDLKTPERFL DGAATFREQQQGQIYRRYQEKLRELNAMDFDDLIMQTVFLWQQNPLVLRYYQQRWQHILVDEYQDTNHAQYILVRLLAGK GDNLCVVGDPDQGIYGWRGADIGNILAFEEDFPRARVILLEENYRSTRPILQAANAVIQHNEGRREKRLWTRRREGELLH LYRATDERDEGRFIAGEVYRRHQQEGRPFSDFAVLYRTHAQSRALEEAFIQAGVPYEIVGGLKFYQRKEIKDILAYLRVI ANPDDSLSLLRIINVPRRGIGEATLARLEAAATSEGESLYRVLERVDTIPGIPARGRQALRELVEMLDNLRQQQEKITVT DLVATILQETGYQAELEAERTPEAQARLENLKEFQTVTRSYDQGAPESSLGDFLTQVALVAESDTYSGNAAVALMTMHTA KGLEFPVVFLAGLEEGVFPHFRSLDDPAEMEEERRLCYVGMTRAREVLYLTHAWTRNLYGSTMSNPPSRFLDEIPADLIQ GEGTGLRSGVLSRTSEERDDRGRSTRRQPAPARSTRASWQVGDKVQHDAWGLGVIVKISGEGDDAIISVAFPGRGIKQLA LRYAPIRKA
Sequences:
>Translated_729_residues MKVLADFMALLNGPQQEAVKHRGTPLLVLAGAGSGKTRVLTYRVAALIQEGVRPENILAVTFTNKAAQEMKERLEGLVGE AARGLWVSTFHSACVRILRREAHLLGYRPNFVIYDTDDQQAALKEVLKELDLDDKKYPPRSLAQVISMAKNDLKTPERFL DGAATFREQQQGQIYRRYQEKLRELNAMDFDDLIMQTVFLWQQNPLVLRYYQQRWQHILVDEYQDTNHAQYILVRLLAGK GDNLCVVGDPDQGIYGWRGADIGNILAFEEDFPRARVILLEENYRSTRPILQAANAVIQHNEGRREKRLWTRRREGELLH LYRATDERDEGRFIAGEVYRRHQQEGRPFSDFAVLYRTHAQSRALEEAFIQAGVPYEIVGGLKFYQRKEIKDILAYLRVI ANPDDSLSLLRIINVPRRGIGEATLARLEAAATSEGESLYRVLERVDTIPGIPARGRQALRELVEMLDNLRQQQEKITVT DLVATILQETGYQAELEAERTPEAQARLENLKEFQTVTRSYDQGAPESSLGDFLTQVALVAESDTYSGNAAVALMTMHTA KGLEFPVVFLAGLEEGVFPHFRSLDDPAEMEEERRLCYVGMTRAREVLYLTHAWTRNLYGSTMSNPPSRFLDEIPADLIQ GEGTGLRSGVLSRTSEERDDRGRSTRRQPAPARSTRASWQVGDKVQHDAWGLGVIVKISGEGDDAIISVAFPGRGIKQLA LRYAPIRKA >Mature_729_residues MKVLADFMALLNGPQQEAVKHRGTPLLVLAGAGSGKTRVLTYRVAALIQEGVRPENILAVTFTNKAAQEMKERLEGLVGE AARGLWVSTFHSACVRILRREAHLLGYRPNFVIYDTDDQQAALKEVLKELDLDDKKYPPRSLAQVISMAKNDLKTPERFL DGAATFREQQQGQIYRRYQEKLRELNAMDFDDLIMQTVFLWQQNPLVLRYYQQRWQHILVDEYQDTNHAQYILVRLLAGK GDNLCVVGDPDQGIYGWRGADIGNILAFEEDFPRARVILLEENYRSTRPILQAANAVIQHNEGRREKRLWTRRREGELLH LYRATDERDEGRFIAGEVYRRHQQEGRPFSDFAVLYRTHAQSRALEEAFIQAGVPYEIVGGLKFYQRKEIKDILAYLRVI ANPDDSLSLLRIINVPRRGIGEATLARLEAAATSEGESLYRVLERVDTIPGIPARGRQALRELVEMLDNLRQQQEKITVT DLVATILQETGYQAELEAERTPEAQARLENLKEFQTVTRSYDQGAPESSLGDFLTQVALVAESDTYSGNAAVALMTMHTA KGLEFPVVFLAGLEEGVFPHFRSLDDPAEMEEERRLCYVGMTRAREVLYLTHAWTRNLYGSTMSNPPSRFLDEIPADLIQ GEGTGLRSGVLSRTSEERDDRGRSTRRQPAPARSTRASWQVGDKVQHDAWGLGVIVKISGEGDDAIISVAFPGRGIKQLA LRYAPIRKA
Specific function: Essential helicase [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase C-terminal domain [H]
Homologues:
Organism=Escherichia coli, GI2367296, Length=722, Percent_Identity=41.6897506925208, Blast_Score=535, Evalue=1e-153, Organism=Escherichia coli, GI48994965, Length=639, Percent_Identity=40.8450704225352, Blast_Score=426, Evalue=1e-120, Organism=Escherichia coli, GI1787196, Length=345, Percent_Identity=29.2753623188406, Blast_Score=98, Evalue=2e-21, Organism=Saccharomyces cerevisiae, GI6322369, Length=714, Percent_Identity=27.8711484593838, Blast_Score=243, Evalue=1e-64, Organism=Saccharomyces cerevisiae, GI6324477, Length=656, Percent_Identity=24.6951219512195, Blast_Score=132, Evalue=2e-31,
Paralogues:
None
Copy number: 3000 [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005751 - InterPro: IPR013986 - InterPro: IPR014017 - InterPro: IPR000212 - InterPro: IPR014016 [H]
Pfam domain/function: PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 82563; Mature: 82563
Theoretical pI: Translated: 6.60; Mature: 6.60
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.1 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKVLADFMALLNGPQQEAVKHRGTPLLVLAGAGSGKTRVLTYRVAALIQEGVRPENILAV CCHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCEEEE TFTNKAAQEMKERLEGLVGEAARGLWVSTFHSACVRILRREAHLLGYRPNFVIYDTDDQQ EECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH AALKEVLKELDLDDKKYPPRSLAQVISMAKNDLKTPERFLDGAATFREQQQGQIYRRYQE HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH KLRELNAMDFDDLIMQTVFLWQQNPLVLRYYQQRWQHILVDEYQDTNHAQYILVRLLAGK HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC GDNLCVVGDPDQGIYGWRGADIGNILAFEEDFPRARVILLEENYRSTRPILQAANAVIQH CCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHC NEGRREKRLWTRRREGELLHLYRATDERDEGRFIAGEVYRRHQQEGRPFSDFAVLYRTHA CCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHH QSRALEEAFIQAGVPYEIVGGLKFYQRKEIKDILAYLRVIANPDDSLSLLRIINVPRRGI HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC GEATLARLEAAATSEGESLYRVLERVDTIPGIPARGRQALRELVEMLDNLRQQQEKITVT CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH DLVATILQETGYQAELEAERTPEAQARLENLKEFQTVTRSYDQGAPESSLGDFLTQVALV HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH AESDTYSGNAAVALMTMHTAKGLEFPVVFLAGLEEGVFPHFRSLDDPAEMEEERRLCYVG CCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHCCCCCCCCHHHCCCCHHHHHHHCCEEEEE MTRAREVLYLTHAWTRNLYGSTMSNPPSRFLDEIPADLIQGEGTGLRSGVLSRTSEERDD HHHHHHEEEEHHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCCCCHHHHHHHCCCHHHHH RGRSTRRQPAPARSTRASWQVGDKVQHDAWGLGVIVKISGEGDDAIISVAFPGRGIKQLA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCHHHHH LRYAPIRKA HHHCCCCCC >Mature Secondary Structure MKVLADFMALLNGPQQEAVKHRGTPLLVLAGAGSGKTRVLTYRVAALIQEGVRPENILAV CCHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCEEEE TFTNKAAQEMKERLEGLVGEAARGLWVSTFHSACVRILRREAHLLGYRPNFVIYDTDDQQ EECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHH AALKEVLKELDLDDKKYPPRSLAQVISMAKNDLKTPERFLDGAATFREQQQGQIYRRYQE HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH KLRELNAMDFDDLIMQTVFLWQQNPLVLRYYQQRWQHILVDEYQDTNHAQYILVRLLAGK HHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCC GDNLCVVGDPDQGIYGWRGADIGNILAFEEDFPRARVILLEENYRSTRPILQAANAVIQH CCCEEEECCCCCCCCCCCCCCCCCEEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHHHC NEGRREKRLWTRRREGELLHLYRATDERDEGRFIAGEVYRRHQQEGRPFSDFAVLYRTHA CCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHH QSRALEEAFIQAGVPYEIVGGLKFYQRKEIKDILAYLRVIANPDDSLSLLRIINVPRRGI HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCC GEATLARLEAAATSEGESLYRVLERVDTIPGIPARGRQALRELVEMLDNLRQQQEKITVT CHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH DLVATILQETGYQAELEAERTPEAQARLENLKEFQTVTRSYDQGAPESSLGDFLTQVALV HHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH AESDTYSGNAAVALMTMHTAKGLEFPVVFLAGLEEGVFPHFRSLDDPAEMEEERRLCYVG CCCCCCCCCCEEEEEEEHHHCCCCCHHHHHHCCCCCCCCHHHCCCCHHHHHHHCCEEEEE MTRAREVLYLTHAWTRNLYGSTMSNPPSRFLDEIPADLIQGEGTGLRSGVLSRTSEERDD HHHHHHEEEEHHHHHHHHCCCCCCCCHHHHHHHCCHHHHCCCCCCHHHHHHHCCCHHHHH RGRSTRRQPAPARSTRASWQVGDKVQHDAWGLGVIVKISGEGDDAIISVAFPGRGIKQLA CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCEEEEEECCCCCHHHHH LRYAPIRKA HHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA