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The map label for this gene is xdhB [H]

Identifier: 83590788

GI number: 83590788

Start: 2034459

End: 2035346

Strand: Reverse

Name: xdhB [H]

Synonym: Moth_1956

Alternate gene names: 83590788

Gene position: 2035346-2034459 (Counterclockwise)

Preceding gene: 83590789

Following gene: 83590785

Centisome position: 77.43

GC content: 65.09

Gene sequence:

>888_bases
ATGCCCGAGAAGTATCTCTTCGCCACTTCCCCGGCCGACTGCCTGGCCCTGCTGGCCGCGAACCCTGGGGCGCGCCTCAT
TGCCGGCGGTACTGACCTGGTCATCGACCTCAAGGAAAAAAGGCGGCAGGTTACCACCCTGGTGGATATCACCAGGATAC
CCGAATTAAAAATAATTACCGAAACAAATGGTAAGATTATCCTGGGCGGGGCGGCCACCCACACCCGCGTGGCCACCTCA
TCCCTTATCCGGCAGAAGCTCCCGGCCCTGGCTGCCGCCGCTGCCGCGGTCGGATCCCCCCAGGTGCGCAATGTCGGCAC
CCTGGCCGGCAATGTGGTCAATGCCCAGCCGGCGGCGGATACGGCTGTGGCCCTGGTAGCCCTGGGAGCCGTGGCCACCA
TCCTGGGAGCGGAGGGGGAACGCCAGGTGCCGGTGGCCGACCTCTACGCCGGTGTGGGCCGCTCCCTGGTAGATGCCGGC
CGCGAGATTATAACCAGATTTACCGTGGACCTGTGGGGGGAGGGCGAATCCTCGGCTTTTGTCCGCCTGTCGCCCCGGCG
CGCCCTCTCCCTGCCCATGCTAAACGTGGCCGTCCGGGTGCAGGTCAGGGAAGGGATATGCACCAGGGCGCGTATCTCAA
TCGCCCCGGTGGCGCCCCGGCCCTTCCTGTGCGAAGAAGCGGCCGCCAGCCTCGTGGGCCGGGAACCCACGGCGAAAGCA
ATTGCCAGGGCGGCTTCCGTAGCTAAGGAGGCAGCCCGGCCCAGGGACAGCCTCCTCCGGGGTTCCGGCGCCTACCGGAA
GGACATGACGGCTGTGCTGGTAGCCAGGGCTTTAAGCGAAGCTTTTTCCCGCGCAACCAGCAGGAAAATAGAAAACGATG
TCGAATAG

Upstream 100 bases:

>100_bases
AAAGGCAGCGCTTGCTGCACCTGGACGAGGCGGCCATCGCCGCCCGGGCCCGGGAACTGGCGATCAAAGTCTGGGAGCGG
TTTTAACGGGGAGGGATTCC

Downstream 100 bases:

>100_bases
ATACAAAAAATACCTGGTGAAAAGTTATTACTGCAGGCAAAGACGTCTACATCAGGGTAACGGGGCCCTCATTGTAGACG
TTTTTTTGCGCCCTAAAAAG

Product: molybdopterin dehydrogenase, FAD-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MPEKYLFATSPADCLALLAANPGARLIAGGTDLVIDLKEKRRQVTTLVDITRIPELKIITETNGKIILGGAATHTRVATS
SLIRQKLPALAAAAAAVGSPQVRNVGTLAGNVVNAQPAADTAVALVALGAVATILGAEGERQVPVADLYAGVGRSLVDAG
REIITRFTVDLWGEGESSAFVRLSPRRALSLPMLNVAVRVQVREGICTRARISIAPVAPRPFLCEEAAASLVGREPTAKA
IARAASVAKEAARPRDSLLRGSGAYRKDMTAVLVARALSEAFSRATSRKIENDVE

Sequences:

>Translated_295_residues
MPEKYLFATSPADCLALLAANPGARLIAGGTDLVIDLKEKRRQVTTLVDITRIPELKIITETNGKIILGGAATHTRVATS
SLIRQKLPALAAAAAAVGSPQVRNVGTLAGNVVNAQPAADTAVALVALGAVATILGAEGERQVPVADLYAGVGRSLVDAG
REIITRFTVDLWGEGESSAFVRLSPRRALSLPMLNVAVRVQVREGICTRARISIAPVAPRPFLCEEAAASLVGREPTAKA
IARAASVAKEAARPRDSLLRGSGAYRKDMTAVLVARALSEAFSRATSRKIENDVE
>Mature_294_residues
PEKYLFATSPADCLALLAANPGARLIAGGTDLVIDLKEKRRQVTTLVDITRIPELKIITETNGKIILGGAATHTRVATSS
LIRQKLPALAAAAAAVGSPQVRNVGTLAGNVVNAQPAADTAVALVALGAVATILGAEGERQVPVADLYAGVGRSLVDAGR
EIITRFTVDLWGEGESSAFVRLSPRRALSLPMLNVAVRVQVREGICTRARISIAPVAPRPFLCEEAAASLVGREPTAKAI
ARAASVAKEAARPRDSLLRGSGAYRKDMTAVLVARALSEAFSRATSRKIENDVE

Specific function: Presumed to be a dehydrogenase, but possibly an oxidase. Participates in limited purine salvage (requires aspartate) but does not support aerobic growth on purines as the sole carbon source (purine catabolism) [H]

COG id: COG1319

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789231, Length=280, Percent_Identity=30.7142857142857, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17737937, Length=255, Percent_Identity=25.0980392156863, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005107
- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR002346 [H]

Pfam domain/function: PF03450 CO_deh_flav_C; PF00941 FAD_binding_5 [H]

EC number: =1.17.1.4 [H]

Molecular weight: Translated: 30871; Mature: 30740

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEKYLFATSPADCLALLAANPGARLIAGGTDLVIDLKEKRRQVTTLVDITRIPELKIIT
CCCCEEEECCHHHHHHHHHCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEE
ETNGKIILGGAATHTRVATSSLIRQKLPALAAAAAAVGSPQVRNVGTLAGNVVNAQPAAD
ECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHH
TAVALVALGAVATILGAEGERQVPVADLYAGVGRSLVDAGREIITRFTVDLWGEGESSAF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCEE
VRLSPRRALSLPMLNVAVRVQVREGICTRARISIAPVAPRPFLCEEAAASLVGREPTAKA
EEECCCHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHH
IARAASVAKEAARPRDSLLRGSGAYRKDMTAVLVARALSEAFSRATSRKIENDVE
HHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PEKYLFATSPADCLALLAANPGARLIAGGTDLVIDLKEKRRQVTTLVDITRIPELKIIT
CCCEEEECCHHHHHHHHHCCCCCEEEECCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEE
ETNGKIILGGAATHTRVATSSLIRQKLPALAAAAAAVGSPQVRNVGTLAGNVVNAQPAAD
ECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCHH
TAVALVALGAVATILGAEGERQVPVADLYAGVGRSLVDAGREIITRFTVDLWGEGESSAF
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCEE
VRLSPRRALSLPMLNVAVRVQVREGICTRARISIAPVAPRPFLCEEAAASLVGREPTAKA
EEECCCHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHH
IARAASVAKEAARPRDSLLRGSGAYRKDMTAVLVARALSEAFSRATSRKIENDVE
HHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]