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The map label for this gene is coaD

Identifier: 83590705

GI number: 83590705

Start: 1933041

End: 1933523

Strand: Reverse

Name: coaD

Synonym: Moth_1871

Alternate gene names: 83590705

Gene position: 1933523-1933041 (Counterclockwise)

Preceding gene: 83590706

Following gene: 83590704

Centisome position: 73.55

GC content: 51.55

Gene sequence:

>483_bases
TTGAAGGTGGCTGTATATCCAGGCACCTTTGACCCGATTACTAACGGGCACCTGGATATTATCCGGCGGGCGGTAAGTAT
CTTTGACCGGGTTGTGGTGGGGGTGGCTGCCGATAATTATAAAAAGACCCTGTTTTCCCTGGAAGAAAGGGTGGAGCTGG
TCAGGACCGTCACCAGGGATATACCCGGTGTAACGGTAAAGTCTTTTTCTGGACTCCTGGTCGATTTTGCCCGCCGGGAA
GAGGCCGTGGCTATCGTCAGGGGGCTGCGGGCAGTTTCCGATTTTGAATATGAATTCCAGATGTCGATAATGAATAAAAA
GCTGGCCAGTGACCTGGAGACGGTTTTTCTCATGACGGCTACCGAGTATTCCTTCTTAAGCTCAAGTATCATTCGCCAGG
CAGCCTCCCTGGGGGGGTGTATCCATGGCCTGGTGCCACCTGAAGTCGAGCGAGTTTTGCTAAAACGTTACGGTTTTTTG
TAG

Upstream 100 bases:

>100_bases
GACGACTGGGTTCGAGACGCTAGTAAACTTTGCGCGAAGCCGATAGTTCCGGCGGCGGTGAACGGGATGCCATATAATCG
GAGGAGGAGGTGATAGCCAG

Downstream 100 bases:

>100_bases
GGAGGTGAGTTGATGGAGGACAGGGAAAGCGTTACCGCTGCCGACTTTATTGTCATCAAAGCCCTGGAGAACGGCGTAAC
CATTATCGGCCTGACCCGGG

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 160; Mature: 160

Protein sequence:

>160_residues
MKVAVYPGTFDPITNGHLDIIRRAVSIFDRVVVGVAADNYKKTLFSLEERVELVRTVTRDIPGVTVKSFSGLLVDFARRE
EAVAIVRGLRAVSDFEYEFQMSIMNKKLASDLETVFLMTATEYSFLSSSIIRQAASLGGCIHGLVPPEVERVLLKRYGFL

Sequences:

>Translated_160_residues
MKVAVYPGTFDPITNGHLDIIRRAVSIFDRVVVGVAADNYKKTLFSLEERVELVRTVTRDIPGVTVKSFSGLLVDFARRE
EAVAIVRGLRAVSDFEYEFQMSIMNKKLASDLETVFLMTATEYSFLSSSIIRQAASLGGCIHGLVPPEVERVLLKRYGFL
>Mature_160_residues
MKVAVYPGTFDPITNGHLDIIRRAVSIFDRVVVGVAADNYKKTLFSLEERVELVRTVTRDIPGVTVKSFSGLLVDFARRE
EAVAIVRGLRAVSDFEYEFQMSIMNKKLASDLETVFLMTATEYSFLSSSIIRQAASLGGCIHGLVPPEVERVLLKRYGFL

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=155, Percent_Identity=47.741935483871, Blast_Score=166, Evalue=7e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_MOOTA (Q2RHB8)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430714.1
- HSSP:   Q9WZK0
- ProteinModelPortal:   Q2RHB8
- SMR:   Q2RHB8
- STRING:   Q2RHB8
- GeneID:   3831502
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1871
- NMPDR:   fig|264732.9.peg.1877
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- PhylomeDB:   Q2RHB8
- ProtClustDB:   PRK00168
- BioCyc:   MTHE264732:MOTH_1871-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17864; Mature: 17864

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAVYPGTFDPITNGHLDIIRRAVSIFDRVVVGVAADNYKKTLFSLEERVELVRTVTRD
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IPGVTVKSFSGLLVDFARREEAVAIVRGLRAVSDFEYEFQMSIMNKKLASDLETVFLMTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEYSFLSSSIIRQAASLGGCIHGLVPPEVERVLLKRYGFL
HHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MKVAVYPGTFDPITNGHLDIIRRAVSIFDRVVVGVAADNYKKTLFSLEERVELVRTVTRD
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IPGVTVKSFSGLLVDFARREEAVAIVRGLRAVSDFEYEFQMSIMNKKLASDLETVFLMTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
TEYSFLSSSIIRQAASLGGCIHGLVPPEVERVLLKRYGFL
HHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA