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The map label for this gene is moeA [H]

Identifier: 83590654

GI number: 83590654

Start: 1879495

End: 1880790

Strand: Reverse

Name: moeA [H]

Synonym: Moth_1820

Alternate gene names: 83590654

Gene position: 1880790-1879495 (Counterclockwise)

Preceding gene: 83590655

Following gene: 83590653

Centisome position: 71.55

GC content: 67.36

Gene sequence:

>1296_bases
GTGGCTGGAGTAAACGCTTCCTTTAGCCTGGAGGAAGGGCGGGAACTCCTCCTGGCCGGGTTAAAACCGACGGGAAGGGT
GAAAATAAAACTGGCTGAGGCCCCGGGCCGCATCCTGGCGGAACCGGTGGTGGCGCCGTGCTCCTTCCCGCCTTTCCCGC
GTTCCCGGGTGGACGGTTACGCCCTGGGACTGCCCCCGGCCGCCGGCGGGGCATCGGGAAAAATCTACCGGCTGGTGGCT
ACAGTAGCGGCAGGTAGCTGCCCGGCTGTCACCCTGGGACCGGGTACGGCGGCGGCTATTTTCACCGGCGCCCGGCTCCC
GGAAGGCACAATAACCGTTATTCCCAGAGAACTGGCGGAGCGCCAGGGGGACCTGGTCATAGTGCCGGAGCTGCCCCCGG
GGGGCAGGTTCATGGAAGCTGCCGGATCGGAGGTGGCGGCCGGGGAAAGGGTCCTGGCCGCCGGCACTGAACTGGGACCG
GCGGAAATCGGCCTCCTGGCCGCCCTGGGCCTTACGGAAATAACCGTCTACCGTAGTCCCAGGGCGGTCCTGGCGTCCAG
CGGCAGCGAACTGGTGGAATTGCCTGGCCTCCGGGGAGGCTGCCCCGGCGGCCGGCAGGCAGGTGGCGAGGCGATAAGCC
CTGTTGCCAGCCAGGTTCGAGCACTCGGGCCCCGCATTTATAATAGTAATTTCTATGCGCTGGCGGCAGCCGCCAGCCGC
GATGGCGCTCGGGTAATCCCCCTCGGGCCGCTGGCCGATGAACTGGAGGAACAGGTAGAGGCTTACCGGAAAGCCCTGGA
GGAGGGCGATGTACTTCTAACTACCGGTGGAGCCGGCGGTAGCATCCGTGACCTGACGGCGGCGGCCTTTACCGGTGCCG
GGGGAGAAATCCTCTTTACGACAATCCGGATGCGCCCGGGCCGGCGGGTGATAGCCGCCCGCCGGGGGGATAAATTACTC
CTGGGCCTGCCGGGCAATCCACCGGCAGCGCTGGTGGCTTACTACCTCCTGGCGGCACCGGTGATTCGCGCCCTGGGGGG
GAGGGAAGTCCTACCGGCAACCTTCCCGGCGGTACTGACGGCGGCCATAGATAAACCGAGGCCCGAACGGGCCTTTATCT
GGGCCCGGGCCTGGCCCGGTACGACCGGCTGGCAGGTAGCGCCCCTGCCGCGTCGCCCGGGGGGTATCCGCGCCGCTATT
GGGGCCAACGCCCTCATTGACCTCCCCGCCGGCCCGGCTCCTGGAGCCGGGGAAGAGGTAAGGGTGGTGCTGCTTACTGC
CCGGGGTTCACAATAA

Upstream 100 bases:

>100_bases
CTGGCAGCCTTCGAAGCCTGCCTGCTAAGGCAAGAATACCAGGCCTTTGCCTTTTACCCCGGCGTCAGGGCGCAGTACAT
ATTTAAGGATGGAAACAGCC

Downstream 100 bases:

>100_bases
GGCCTGCCTGATAATAAGTAGATTGCCTGATAGTCTTAGGGGGTACAATCATGAGCGATTCCAAAGATAAGCGGATCCCG
GTTATCTCTGTTGTCGGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MAGVNASFSLEEGRELLLAGLKPTGRVKIKLAEAPGRILAEPVVAPCSFPPFPRSRVDGYALGLPPAAGGASGKIYRLVA
TVAAGSCPAVTLGPGTAAAIFTGARLPEGTITVIPRELAERQGDLVIVPELPPGGRFMEAAGSEVAAGERVLAAGTELGP
AEIGLLAALGLTEITVYRSPRAVLASSGSELVELPGLRGGCPGGRQAGGEAISPVASQVRALGPRIYNSNFYALAAAASR
DGARVIPLGPLADELEEQVEAYRKALEEGDVLLTTGGAGGSIRDLTAAAFTGAGGEILFTTIRMRPGRRVIAARRGDKLL
LGLPGNPPAALVAYYLLAAPVIRALGGREVLPATFPAVLTAAIDKPRPERAFIWARAWPGTTGWQVAPLPRRPGGIRAAI
GANALIDLPAGPAPGAGEEVRVVLLTARGSQ

Sequences:

>Translated_431_residues
MAGVNASFSLEEGRELLLAGLKPTGRVKIKLAEAPGRILAEPVVAPCSFPPFPRSRVDGYALGLPPAAGGASGKIYRLVA
TVAAGSCPAVTLGPGTAAAIFTGARLPEGTITVIPRELAERQGDLVIVPELPPGGRFMEAAGSEVAAGERVLAAGTELGP
AEIGLLAALGLTEITVYRSPRAVLASSGSELVELPGLRGGCPGGRQAGGEAISPVASQVRALGPRIYNSNFYALAAAASR
DGARVIPLGPLADELEEQVEAYRKALEEGDVLLTTGGAGGSIRDLTAAAFTGAGGEILFTTIRMRPGRRVIAARRGDKLL
LGLPGNPPAALVAYYLLAAPVIRALGGREVLPATFPAVLTAAIDKPRPERAFIWARAWPGTTGWQVAPLPRRPGGIRAAI
GANALIDLPAGPAPGAGEEVRVVLLTARGSQ
>Mature_430_residues
AGVNASFSLEEGRELLLAGLKPTGRVKIKLAEAPGRILAEPVVAPCSFPPFPRSRVDGYALGLPPAAGGASGKIYRLVAT
VAAGSCPAVTLGPGTAAAIFTGARLPEGTITVIPRELAERQGDLVIVPELPPGGRFMEAAGSEVAAGERVLAAGTELGPA
EIGLLAALGLTEITVYRSPRAVLASSGSELVELPGLRGGCPGGRQAGGEAISPVASQVRALGPRIYNSNFYALAAAASRD
GARVIPLGPLADELEEQVEAYRKALEEGDVLLTTGGAGGSIRDLTAAAFTGAGGEILFTTIRMRPGRRVIAARRGDKLLL
GLPGNPPAALVAYYLLAAPVIRALGGREVLPATFPAVLTAAIDKPRPERAFIWARAWPGTTGWQVAPLPRRPGGIRAAIG
ANALIDLPAGPAPGAGEEVRVVLLTARGSQ

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Homo sapiens, GI66932975, Length=410, Percent_Identity=29.7560975609756, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI10880983, Length=410, Percent_Identity=29.7560975609756, Blast_Score=129, Evalue=7e-30,
Organism=Escherichia coli, GI1787049, Length=346, Percent_Identity=30.635838150289, Blast_Score=125, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI25147659, Length=421, Percent_Identity=29.6912114014252, Blast_Score=128, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17562606, Length=396, Percent_Identity=25.7575757575758, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17136978, Length=396, Percent_Identity=25.7575757575758, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24638841, Length=396, Percent_Identity=25.7575757575758, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 43960; Mature: 43829

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGVNASFSLEEGRELLLAGLKPTGRVKIKLAEAPGRILAEPVVAPCSFPPFPRSRVDGY
CCCCCCCCCHHCCCEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCE
ALGLPPAAGGASGKIYRLVATVAAGSCPAVTLGPGTAAAIFTGARLPEGTITVIPRELAE
EEECCCCCCCCCCEEEEEEEHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEHHHHH
RQGDLVIVPELPPGGRFMEAAGSEVAAGERVLAAGTELGPAEIGLLAALGLTEITVYRSP
HCCCEEEEECCCCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEEECC
RAVLASSGSELVELPGLRGGCPGGRQAGGEAISPVASQVRALGPRIYNSNFYALAAAASR
CCEEECCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEEECCC
DGARVIPLGPLADELEEQVEAYRKALEEGDVLLTTGGAGGSIRDLTAAAFTGAGGEILFT
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEE
TIRMRPGRRVIAARRGDKLLLGLPGNPPAALVAYYLLAAPVIRALGGREVLPATFPAVLT
EEEECCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AAIDKPRPERAFIWARAWPGTTGWQVAPLPRRPGGIRAAIGANALIDLPAGPAPGAGEEV
HHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCE
RVVLLTARGSQ
EEEEEEECCCC
>Mature Secondary Structure 
AGVNASFSLEEGRELLLAGLKPTGRVKIKLAEAPGRILAEPVVAPCSFPPFPRSRVDGY
CCCCCCCCHHCCCEEEEECCCCCCEEEEEEECCCCCEECCCCCCCCCCCCCCCCCCCCE
ALGLPPAAGGASGKIYRLVATVAAGSCPAVTLGPGTAAAIFTGARLPEGTITVIPRELAE
EEECCCCCCCCCCEEEEEEEHHHCCCCCEEEECCCCEEEEEECCCCCCCCEEEEEHHHHH
RQGDLVIVPELPPGGRFMEAAGSEVAAGERVLAAGTELGPAEIGLLAALGLTEITVYRSP
HCCCEEEEECCCCCCCCHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCEEEEEEECC
RAVLASSGSELVELPGLRGGCPGGRQAGGEAISPVASQVRALGPRIYNSNFYALAAAASR
CCEEECCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCEEECCCEEEEEEECCC
DGARVIPLGPLADELEEQVEAYRKALEEGDVLLTTGGAGGSIRDLTAAAFTGAGGEILFT
CCCEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHCCCCCCEEEEE
TIRMRPGRRVIAARRGDKLLLGLPGNPPAALVAYYLLAAPVIRALGGREVLPATFPAVLT
EEEECCCCEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AAIDKPRPERAFIWARAWPGTTGWQVAPLPRRPGGIRAAIGANALIDLPAGPAPGAGEEV
HHHCCCCCCCEEEEEEECCCCCCCEEECCCCCCCCEEEECCCCEEEECCCCCCCCCCCCE
RVVLLTARGSQ
EEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8682795; 11759840 [H]