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The map label for this gene is cobT [H]

Identifier: 83590557

GI number: 83590557

Start: 1764781

End: 1765869

Strand: Reverse

Name: cobT [H]

Synonym: Moth_1721

Alternate gene names: 83590557

Gene position: 1765869-1764781 (Counterclockwise)

Preceding gene: 83590558

Following gene: 83590556

Centisome position: 67.17

GC content: 62.26

Gene sequence:

>1089_bases
ATGATGGGATTAAAGCTGGAGGAGACGGTTAAAGGGATCATGCCTGTCAACGATGCCTGGCGCCGGAAGGCCCGTGAGCA
CTTAAACAACCTGGCCATTCCGGTAGGAAGCCTGGGAAGGCTGCTGGACATCGCCGAACAACTGGCCGCCATAAAGGAAA
GCCTGAAGCCTTCGACGGGTAGCAAGGTGGTCGTCACCATGGCCGGGGACCACGGCGTTGTTGAGGAAGGGGTCAGCACC
TGTCCCCAGAGAGTGACCCTCCAGATGGTTTACAATTTTGTAGCCGGCGGGGCCGGGATCAATGCCCTGGCCGGGGCGGC
CGGGGCCAGGGTAGTGGTTGTGGATATGGGCGTGGCCGGAGATCTGAAGGACCTGGTGGAGCAGGGGAAGATCCTTTCCC
GCAAGGTGGATTACGGAACGCGCAATATGACCAGGGGCCCTGCCATGACCAGGCAACAGGCGGTGCAGGCCCTGGAGACC
GGCATCAACATCGCCGGAGACCTGGTCAATGAAGGCGTTGAACTGCTGGGAACAGGGGATATGGGGATCGGCAACACCAC
CCCGAGCAGCGCCATTCTGGCGGCCCTTTCCGGCCTGCCGGTCCGGGAGGTGACGGGGAGGGGCACCGGGATCGACGACG
AGACCCTGGCAAGGAAGGTCCAGGTGATCGAGAGGGCCCTTGCCCTGAACAGGCCGGACCCGGGTGACCCAGTAGACGTT
CTGGCCAAGGTGGGCGGTTTCGAGATCGGGGGAATTGCGGGGTTGATTCTCGGGGCGGCCTACTACCGGGTGCCAGTTGT
GGTGGACGGATTTATATCCACCGCCGGTGCCCTCCTGGCGAAACAACTCGCCCCCCGGGCGGTTGATTACATGATCGCCG
CCCACCGGTCCATGGAGTACGGGCACAGGTATATGCTCAAAGAGCTCGGCCTGCGGCCGCTGCTCGATTTAGACATGCGC
CTGGGAGAGGGTACAGGGGCTGCCCTGGCCATGTGCATTGTAGAAGGGGCGGCGCGGGTGATCGGCGAGATGCTCACCTT
TGAAGATGCCGGGGTCGCCAGAAATAAGTCCAGGGAGTATGCGGTATGA

Upstream 100 bases:

>100_bases
GGGGAAGACGGGGTTTGTGCTGCCTGTGGGACGAACTGCGCAGCCCTGGTGGCCGCCCGTTATTTCGGGATGAACTGAGG
CGTGAAAACCAGGGGGGAAA

Downstream 100 bases:

>100_bases
AACCAGGCTTTCTCAAGTATGACCCCCAGGCCCCTTGCCCCCAGTACCTGGAGGATCTGGCTACCGGTTACTGGTTTTCG
GAAGTCCTCTTCACCGCCGT

Product: nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MMGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTGSKVVVTMAGDHGVVEEGVST
CPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAGDLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALET
GINIAGDLVNEGVELLGTGDMGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDV
LAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEYGHRYMLKELGLRPLLDLDMR
LGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREYAV

Sequences:

>Translated_362_residues
MMGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTGSKVVVTMAGDHGVVEEGVST
CPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAGDLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALET
GINIAGDLVNEGVELLGTGDMGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDV
LAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEYGHRYMLKELGLRPLLDLDMR
LGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREYAV
>Mature_362_residues
MMGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTGSKVVVTMAGDHGVVEEGVST
CPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAGDLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALET
GINIAGDLVNEGVELLGTGDMGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDV
LAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEYGHRYMLKELGLRPLLDLDMR
LGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREYAV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=340, Percent_Identity=42.3529411764706, Blast_Score=249, Evalue=2e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 38010; Mature: 38010

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTG
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SKVVVTMAGDHGVVEEGVSTCPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCC
DLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALETGINIAGDLVNEGVELLGTGD
CHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHEEECCC
MGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDV
CCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHRYMLKELGLRPLLDLDMRLGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREY
HHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AV
CC
>Mature Secondary Structure
MMGLKLEETVKGIMPVNDAWRRKAREHLNNLAIPVGSLGRLLDIAEQLAAIKESLKPSTG
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
SKVVVTMAGDHGVVEEGVSTCPQRVTLQMVYNFVAGGAGINALAGAAGARVVVVDMGVAG
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEEEEECCCCC
DLKDLVEQGKILSRKVDYGTRNMTRGPAMTRQQAVQALETGINIAGDLVNEGVELLGTGD
CHHHHHHHCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCHHEEECCC
MGIGNTTPSSAILAALSGLPVREVTGRGTGIDDETLARKVQVIERALALNRPDPGDPVDV
CCCCCCCCHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHH
LAKVGGFEIGGIAGLILGAAYYRVPVVVDGFISTAGALLAKQLAPRAVDYMIAAHRSMEY
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHRYMLKELGLRPLLDLDMRLGEGTGAALAMCIVEGAARVIGEMLTFEDAGVARNKSREY
HHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
AV
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA