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The map label for this gene is ruvC

Identifier: 83590538

GI number: 83590538

Start: 1739208

End: 1739711

Strand: Reverse

Name: ruvC

Synonym: Moth_1702

Alternate gene names: 83590538

Gene position: 1739711-1739208 (Counterclockwise)

Preceding gene: 83590539

Following gene: 83590537

Centisome position: 66.18

GC content: 63.1

Gene sequence:

>504_bases
ATGCTGATCCTGGGAATAGACCCGGGGACGGCGATTGTCGGTTACGGCCTGGTGGAGGCCCGGGCTGGACAAACCCGCGC
CCTGGTATACGATTGTATCCGGACACCGGCGGGGGAGGATCCCTGCCGGCGGCTGGCAACCATTTACGCCGGCATAAGGG
AGCTAATCGAGCGCTTGCAGCCAGAAACCATGGCCGTGGAAGAACTCTTCTTTAACAAAAACAGCAAGACAGCCCTAGCC
GTTGGCCAGGCCAGGGGCGTGATCCTTCTGGCCGCGGCCCATACCGGTCTGCCGGTGGCCGAGTATACCCCCCTGGAGGT
CAAGCAGGCAGTGGCCGGTTTCGGCCGGGCGCCCAAGGAACAGGTCCAGCGTATGGTCCAGGCTTTGCTGGGCCTGGAAG
AAAAACCCCGGCCAGATGATGTGGCCGATGCCCTGGCGGTAGCCGTATGTCATGCCAGCTTCGCGCCCTGGCGGCAAAGG
GAAAAGGAGGTGGCTGGCCGTTGA

Upstream 100 bases:

>100_bases
AGGCAGAGGTTTTTTTGAACCGGTACTCCTAAAGAAGATGGAGCATACCCAAACCAATAATAACCATTTTTGATAGAACC
ATATTTTCGGGGGAATAATT

Downstream 100 bases:

>100_bases
TCGGGTACCTGCGGGGTAGGTTACATCTGGTAACACCGGAGGGTATCCTCCTGGAGACCGGAGGGATCGGCTGGCTGGTA
CGTACAGTGACCAATCGTTC

Product: crossover junction endodeoxyribonuclease RuvC

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MLILGIDPGTAIVGYGLVEARAGQTRALVYDCIRTPAGEDPCRRLATIYAGIRELIERLQPETMAVEELFFNKNSKTALA
VGQARGVILLAAAHTGLPVAEYTPLEVKQAVAGFGRAPKEQVQRMVQALLGLEEKPRPDDVADALAVAVCHASFAPWRQR
EKEVAGR

Sequences:

>Translated_167_residues
MLILGIDPGTAIVGYGLVEARAGQTRALVYDCIRTPAGEDPCRRLATIYAGIRELIERLQPETMAVEELFFNKNSKTALA
VGQARGVILLAAAHTGLPVAEYTPLEVKQAVAGFGRAPKEQVQRMVQALLGLEEKPRPDDVADALAVAVCHASFAPWRQR
EKEVAGR
>Mature_167_residues
MLILGIDPGTAIVGYGLVEARAGQTRALVYDCIRTPAGEDPCRRLATIYAGIRELIERLQPETMAVEELFFNKNSKTALA
VGQARGVILLAAAHTGLPVAEYTPLEVKQAVAGFGRAPKEQVQRMVQALLGLEEKPRPDDVADALAVAVCHASFAPWRQR
EKEVAGR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=153, Percent_Identity=44.4444444444444, Blast_Score=124, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_MOOTA (Q2RHT5)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430547.1
- ProteinModelPortal:   Q2RHT5
- SMR:   Q2RHT5
- STRING:   Q2RHT5
- GeneID:   3833151
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1702
- NMPDR:   fig|264732.9.peg.1701
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   Q2RHT5
- BioCyc:   MTHE264732:MOTH_1702-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18047; Mature: 18047

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILGIDPGTAIVGYGLVEARAGQTRALVYDCIRTPAGEDPCRRLATIYAGIRELIERLQ
CEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
PETMAVEELFFNKNSKTALAVGQARGVILLAAAHTGLPVAEYTPLEVKQAVAGFGRAPKE
CHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHH
QVQRMVQALLGLEEKPRPDDVADALAVAVCHASFAPWRQREKEVAGR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MLILGIDPGTAIVGYGLVEARAGQTRALVYDCIRTPAGEDPCRRLATIYAGIRELIERLQ
CEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHC
PETMAVEELFFNKNSKTALAVGQARGVILLAAAHTGLPVAEYTPLEVKQAVAGFGRAPKE
CHHHHHHHHHHCCCCCEEEEEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCCCHH
QVQRMVQALLGLEEKPRPDDVADALAVAVCHASFAPWRQREKEVAGR
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA