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The map label for this gene is aspS

Identifier: 83590512

GI number: 83590512

Start: 1712258

End: 1714060

Strand: Reverse

Name: aspS

Synonym: Moth_1676

Alternate gene names: 83590512

Gene position: 1714060-1712258 (Counterclockwise)

Preceding gene: 83590513

Following gene: 83590511

Centisome position: 65.2

GC content: 63.45

Gene sequence:

>1803_bases
ATGGTAGTGGTTGAGGGTTTGGCCGGACTCCACCGCAGCCACGGCTGCGGGGAGTTGACGGCGGCTGATGCCGGCAAGGA
AGTCACCCTGATGGGCTGGGTCCACCGGCGCCGGGATCACGGCGGCCTGATTTTTATTGACCTCCGGGATCGCTCCGGCC
TGGTGCAGGTAGTTTGCGACCCGAAGTCCGGGCCGGCCTTTCAAAAGGCAGAAGAAGTACGCAACGAGTATGTGGTGGCC
GTCAGGGGCCTGGTGCGCCGTCGGCCCGAGGGGACTGTCAACCCCAAACTGCCTACCGGCGAAATCGAAGTGGTGGCCGA
GGAATTTCGCCTGCTAAACCGGGCCAAGACGCCGCCCTTTTATATCGACGACGGCATTGATGTGGATGAAGCCTTACGCC
TGCGTTACCGGTACCTGGACCTGCGCCGGCCGGAGATGCAGCGGCTCCTTTACCTGCGTTACCGGACTACCAGGGCCATC
CGCGACTTCCTGGACGCCCGCGGTTTCTGGGAGATTGAAACCCCCATGCTGACCCGCAGCACACCGGAAGGGGCCCGGGA
CTTCCTGGTGCCCAGCCGGCTGCGACCCGGGGAGTTCTTCGCCCTGCCCCAATCCCCCCAGCTTTTCAAACAGATCCTCA
TGGTGGCCGGGGTAGAGCGGTACTTTCAGATCGTCCGCTGCTTCCGGGATGAGGACCTGCGGGCCGACCGCCAGCCGGAG
TTTACCCAGCTGGATATGGAGATGTCCTTTGTCCAGCGGGAGGATATCCTCAAACTAGTCGAGGAACTCATGGCCTATGT
TTTCCGGGAGACCCTGGGAGTGGAGCTGGCCCTGCCCCTGCCACGCCTAACTTACCGGGAGGCCATGGACCGTTACGGCT
CCGACAAGCCCGATATCCGTTTCGGTATGGAGATAGTAGACGTATCCGACCTGGTGGCCGGCTGCGGCTTTAAAGTTTTT
GCCGAGGCCGTTGCCCGCGGGGGCGTGGTACGCGGTCTCTGCGCCCCGGGCTGCGCCGGGTACTCCCGTCGGGAACTGGA
TGAGCTGACCAGGCAGGCGGCGGTCTTCGGCGCTAAAGGGCTGGCCTGGATGGCCGTCACCCCCGAGGGCATCCGTTCCC
CCATTGCCAAGTTCTTCACCTCCGGCGAGCTGGAGGGCCTGGTCGCCCGCCTGGCAGGCAAGCCCGGCGACCTCCTCCTC
TTTGTGGCCGATACGGAAACGACGGCCGCCACGGCCCTGGGAGCCCTGCGCCTGGAAATGGGGCGGCGCCTGCACCTCTA
TGATCCGGAACAGCTGGCCTTTACCTGGGTGACGGAGTTTCCCCTCCTGGAATACAGTGCAGAAGAGAAGCGTTATGTAG
CCGTGCACCATCCCTTTACCATGCCCATGGAAGAAGACTGGCCCCTGCTGGACAGCGACCCCCTGCGGGTCCGGGCCCTG
GCCTACGACCTGGTCTTAAACGGCGTCGAGCTGGGCGGGGGCAGTATCCGGATTCACCGCCGGGACATCCAGGAGAAGAT
GTTTAATCTGCTGGGCTTTACCCCGGAGGCCGCACGGGATAAATTCGGGTTTTTGCTGGATGCCTTTGAATACGGTACCC
CGCCCCACGGCGGCATCGCCTTTGGCCTGGACCGGATGCTGATGCTTATGGCCCGGCGGGATACTATCCGCGATTGCATC
CCTTTCCCCAAGACCCAGAGCGGCACCTGCCTGATGACGGCGGCCCCCTCGGGCGTATCCCCGGAGCAACTCCAGGAACT
CCACCTACGGAGCACGGCACGAAAGAGTACCAATCCTGCCTGA

Upstream 100 bases:

>100_bases
CCCGGGGCCGGGTTTCAGTACGCCGCCTGGACGCCGGCAGCCAGGAAGAGGTCCCCCTGGCAGCGGTAGTAGATTATTGC
AGGAAAATGAAGGAGAGTGG

Downstream 100 bases:

>100_bases
AACGCCTGATCCGGTAACAGGTGGCATGGCCCGGTACTTGCAAAAACTTTAAGTTTATGTTAATATCATTGGTGTCAAGG
GAAAACGAAAAGATTTTTAC

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MVVVEGLAGLHRSHGCGELTAADAGKEVTLMGWVHRRRDHGGLIFIDLRDRSGLVQVVCDPKSGPAFQKAEEVRNEYVVA
VRGLVRRRPEGTVNPKLPTGEIEVVAEEFRLLNRAKTPPFYIDDGIDVDEALRLRYRYLDLRRPEMQRLLYLRYRTTRAI
RDFLDARGFWEIETPMLTRSTPEGARDFLVPSRLRPGEFFALPQSPQLFKQILMVAGVERYFQIVRCFRDEDLRADRQPE
FTQLDMEMSFVQREDILKLVEELMAYVFRETLGVELALPLPRLTYREAMDRYGSDKPDIRFGMEIVDVSDLVAGCGFKVF
AEAVARGGVVRGLCAPGCAGYSRRELDELTRQAAVFGAKGLAWMAVTPEGIRSPIAKFFTSGELEGLVARLAGKPGDLLL
FVADTETTAATALGALRLEMGRRLHLYDPEQLAFTWVTEFPLLEYSAEEKRYVAVHHPFTMPMEEDWPLLDSDPLRVRAL
AYDLVLNGVELGGGSIRIHRRDIQEKMFNLLGFTPEAARDKFGFLLDAFEYGTPPHGGIAFGLDRMLMLMARRDTIRDCI
PFPKTQSGTCLMTAAPSGVSPEQLQELHLRSTARKSTNPA

Sequences:

>Translated_600_residues
MVVVEGLAGLHRSHGCGELTAADAGKEVTLMGWVHRRRDHGGLIFIDLRDRSGLVQVVCDPKSGPAFQKAEEVRNEYVVA
VRGLVRRRPEGTVNPKLPTGEIEVVAEEFRLLNRAKTPPFYIDDGIDVDEALRLRYRYLDLRRPEMQRLLYLRYRTTRAI
RDFLDARGFWEIETPMLTRSTPEGARDFLVPSRLRPGEFFALPQSPQLFKQILMVAGVERYFQIVRCFRDEDLRADRQPE
FTQLDMEMSFVQREDILKLVEELMAYVFRETLGVELALPLPRLTYREAMDRYGSDKPDIRFGMEIVDVSDLVAGCGFKVF
AEAVARGGVVRGLCAPGCAGYSRRELDELTRQAAVFGAKGLAWMAVTPEGIRSPIAKFFTSGELEGLVARLAGKPGDLLL
FVADTETTAATALGALRLEMGRRLHLYDPEQLAFTWVTEFPLLEYSAEEKRYVAVHHPFTMPMEEDWPLLDSDPLRVRAL
AYDLVLNGVELGGGSIRIHRRDIQEKMFNLLGFTPEAARDKFGFLLDAFEYGTPPHGGIAFGLDRMLMLMARRDTIRDCI
PFPKTQSGTCLMTAAPSGVSPEQLQELHLRSTARKSTNPA
>Mature_600_residues
MVVVEGLAGLHRSHGCGELTAADAGKEVTLMGWVHRRRDHGGLIFIDLRDRSGLVQVVCDPKSGPAFQKAEEVRNEYVVA
VRGLVRRRPEGTVNPKLPTGEIEVVAEEFRLLNRAKTPPFYIDDGIDVDEALRLRYRYLDLRRPEMQRLLYLRYRTTRAI
RDFLDARGFWEIETPMLTRSTPEGARDFLVPSRLRPGEFFALPQSPQLFKQILMVAGVERYFQIVRCFRDEDLRADRQPE
FTQLDMEMSFVQREDILKLVEELMAYVFRETLGVELALPLPRLTYREAMDRYGSDKPDIRFGMEIVDVSDLVAGCGFKVF
AEAVARGGVVRGLCAPGCAGYSRRELDELTRQAAVFGAKGLAWMAVTPEGIRSPIAKFFTSGELEGLVARLAGKPGDLLL
FVADTETTAATALGALRLEMGRRLHLYDPEQLAFTWVTEFPLLEYSAEEKRYVAVHHPFTMPMEEDWPLLDSDPLRVRAL
AYDLVLNGVELGGGSIRIHRRDIQEKMFNLLGFTPEAARDKFGFLLDAFEYGTPPHGGIAFGLDRMLMLMARRDTIRDCI
PFPKTQSGTCLMTAAPSGVSPEQLQELHLRSTARKSTNPA

Specific function: Unknown

COG id: COG0173

COG function: function code J; Aspartyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI40789249, Length=591, Percent_Identity=42.8087986463621, Blast_Score=443, Evalue=1e-124,
Organism=Homo sapiens, GI45439306, Length=273, Percent_Identity=28.2051282051282, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI194272210, Length=268, Percent_Identity=27.9850746268657, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI5031815, Length=268, Percent_Identity=27.9850746268657, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI4758762, Length=247, Percent_Identity=29.5546558704453, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI226491502, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI1788173, Length=593, Percent_Identity=49.4097807757167, Blast_Score=576, Evalue=1e-165,
Organism=Escherichia coli, GI1790571, Length=320, Percent_Identity=30.3125, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1789256, Length=337, Percent_Identity=29.080118694362, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566633, Length=595, Percent_Identity=35.7983193277311, Blast_Score=330, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI71994340, Length=245, Percent_Identity=25.3061224489796, Blast_Score=86, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17551876, Length=278, Percent_Identity=25.8992805755396, Blast_Score=86, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17535925, Length=249, Percent_Identity=25.7028112449799, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17535927, Length=258, Percent_Identity=25.1937984496124, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71984122, Length=301, Percent_Identity=27.5747508305648, Blast_Score=81, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6325153, Length=647, Percent_Identity=33.3848531684699, Blast_Score=292, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6323011, Length=275, Percent_Identity=28.7272727272727, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6321807, Length=313, Percent_Identity=24.6006389776358, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6320242, Length=261, Percent_Identity=28.735632183908, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324256, Length=162, Percent_Identity=27.7777777777778, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24584738, Length=589, Percent_Identity=38.7096774193548, Blast_Score=383, Evalue=1e-106,
Organism=Drosophila melanogaster, GI17136276, Length=264, Percent_Identity=28.4090909090909, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24640851, Length=252, Percent_Identity=30.1587301587302, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24640849, Length=252, Percent_Identity=30.1587301587302, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI19921528, Length=236, Percent_Identity=30.0847457627119, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: 1320 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYD_MOOTA (Q2RHW1)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430521.1
- ProteinModelPortal:   Q2RHW1
- SMR:   Q2RHW1
- STRING:   Q2RHW1
- GeneID:   3831947
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1676
- NMPDR:   fig|264732.9.peg.1674
- eggNOG:   COG0173
- HOGENOM:   HBG396032
- OMA:   AFPKTQQ
- PhylomeDB:   Q2RHW1
- ProtClustDB:   PRK00476
- BioCyc:   MTHE264732:MOTH_1676-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_B
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020564
- InterPro:   IPR004524
- InterPro:   IPR018153
- InterPro:   IPR002312
- InterPro:   IPR004115
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.30.1360.30
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PANTHER:   PTHR22594:SF5
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00459

Pfam domain/function: PF02938 GAD; PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 67679; Mature: 67679

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVVEGLAGLHRSHGCGELTAADAGKEVTLMGWVHRRRDHGGLIFIDLRDRSGLVQVVCD
CEEECCHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCEEEEEEC
PKSGPAFQKAEEVRNEYVVAVRGLVRRRPEGTVNPKLPTGEIEVVAEEFRLLNRAKTPPF
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
YIDDGIDVDEALRLRYRYLDLRRPEMQRLLYLRYRTTRAIRDFLDARGFWEIETPMLTRS
EECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECC
TPEGARDFLVPSRLRPGEFFALPQSPQLFKQILMVAGVERYFQIVRCFRDEDLRADRQPE
CCCCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FTQLDMEMSFVQREDILKLVEELMAYVFRETLGVELALPLPRLTYREAMDRYGSDKPDIR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCE
FGMEIVDVSDLVAGCGFKVFAEAVARGGVVRGLCAPGCAGYSRRELDELTRQAAVFGAKG
ECEEEECHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
LAWMAVTPEGIRSPIAKFFTSGELEGLVARLAGKPGDLLLFVADTETTAATALGALRLEM
EEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
GRRLHLYDPEQLAFTWVTEFPLLEYSAEEKRYVAVHHPFTMPMEEDWPLLDSDPLRVRAL
CCEEEEECCHHHEEEEEECCCCEECCCCCCEEEEEECCEECCCCCCCCCCCCCCCCHHHH
AYDLVLNGVELGGGSIRIHRRDIQEKMFNLLGFTPEAARDKFGFLLDAFEYGTPPHGGIA
HHHHHHCCEEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
FGLDRMLMLMARRDTIRDCIPFPKTQSGTCLMTAAPSGVSPEQLQELHLRSTARKSTNPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MVVVEGLAGLHRSHGCGELTAADAGKEVTLMGWVHRRRDHGGLIFIDLRDRSGLVQVVCD
CEEECCHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHCCCCCEEEEEECCCCCEEEEEEC
PKSGPAFQKAEEVRNEYVVAVRGLVRRRPEGTVNPKLPTGEIEVVAEEFRLLNRAKTPPF
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCE
YIDDGIDVDEALRLRYRYLDLRRPEMQRLLYLRYRTTRAIRDFLDARGFWEIETPMLTRS
EECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEECC
TPEGARDFLVPSRLRPGEFFALPQSPQLFKQILMVAGVERYFQIVRCFRDEDLRADRQPE
CCCCHHHCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FTQLDMEMSFVQREDILKLVEELMAYVFRETLGVELALPLPRLTYREAMDRYGSDKPDIR
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHCCCCCCCE
FGMEIVDVSDLVAGCGFKVFAEAVARGGVVRGLCAPGCAGYSRRELDELTRQAAVFGAKG
ECEEEECHHHHHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCC
LAWMAVTPEGIRSPIAKFFTSGELEGLVARLAGKPGDLLLFVADTETTAATALGALRLEM
EEEEEECCHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHH
GRRLHLYDPEQLAFTWVTEFPLLEYSAEEKRYVAVHHPFTMPMEEDWPLLDSDPLRVRAL
CCEEEEECCHHHEEEEEECCCCEECCCCCCEEEEEECCEECCCCCCCCCCCCCCCCHHHH
AYDLVLNGVELGGGSIRIHRRDIQEKMFNLLGFTPEAARDKFGFLLDAFEYGTPPHGGIA
HHHHHHCCEEECCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCHH
FGLDRMLMLMARRDTIRDCIPFPKTQSGTCLMTAAPSGVSPEQLQELHLRSTARKSTNPA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA