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The map label for this gene is feoB2 [H]

Identifier: 83590252

GI number: 83590252

Start: 1452318

End: 1453709

Strand: Reverse

Name: feoB2 [H]

Synonym: Moth_1405

Alternate gene names: 83590252

Gene position: 1453709-1452318 (Counterclockwise)

Preceding gene: 83590253

Following gene: 83590250

Centisome position: 55.3

GC content: 61.14

Gene sequence:

>1392_bases
ATGGCTAATATGGAAACCCGGCGGCTCTTAAGCCAGGCCAGGAGCTTGACGGAGGGGCTGGAGGAAAACCTGCGGGACAG
GATTGTTACTGCCCTTTATGCCCGGGCGGAGGGCATCGCTGCCCGGGTCATTAAAAAGAACCCTTCCCCGCGCCGTGACT
GGGACCGGCGGTTGGATACCGTTTTGACTTCCCGGCTGTGGGGTTATCCCTTAATGCTGATCCTGCTGGCTGCCGTTTTC
TGGCTTACTGTTAGCGGTGCCAACTACCCCTCAGCGCTCCTGGGCCGACTCCTCTTCGGTTTCCAGGATATCCTGTCGGG
CTTATTTGGCCGACTGGGGGCACCGGACTGGTTGCACGGCATCCTCGTCCTGGGGATGTACCGTACCCTGGCCTGGGTGG
TTTCTGTGATGCTGCCTCCCATGGCCATTTTCTTCCCCCTGTTTACCCTGCTGGAAGACCTGGGGTACCTGCCCCGGGTG
GCTTTTAATCTGGATCACCTCTTTCACAGGGCCGGCGCCCACGGGAAACAGGCCCTGACCATGTGCATGGGCTTCGGCTG
CAACGCCGCCGGCGTTGTCGGCTGTCGTATTATCGAATCGCCCCGGGAGCGTTTAATCGCCATCCTGACCAATAACTTCG
CTCCCTGTAACGGCCGCTTTCCGACCCTGATAGCCCTGGCCACCATTTTTCTAGGCGGCCTTGTCGCTCCGTCCGGCAGG
GCAGCCGTGGCCGCCCTCAGTGTCGCCGGGATTGTTTTACTGGGTATCCTCCTCATGTTTCTCACTTCCTGGCTCCTCTC
CCGGACGATCCTAAAGGGAGTTCCCTCTGCCTTTACCCTGGAACTGCCCCCCTACCGGCCGCCCCAGGTCCTGCGGGTCA
TTGTCCGTTCCGTCTTTGACCGCACCCTCTTCGTCCTGGCCCGGGCCGTCGTCGTTGCCGCCCCAGCCGGGGCCCTCACC
TGGGCCCTGGCCAACATCCACGTGGGGGGAGTCAGTATTATCGCCCACCTGGCGGGGTGGTTGCAGCCCCTGGGGCGGGT
CGTAGGCCTGGACGGCTATATCCTCCTGGCCTTCATCCTGGGCCTGCCGGCCAACGAGATCGTCATTCCCATTTTACTGA
TGGGTTACCTGGCGACGGGCATGCTCACCGACCTGGATAGCCTGGCGGCCCTGGGCAGCGTGCTCACCAGCCACGGCTGG
ACCACCGTCACCGCCCTGAATATGATGCTCTTTTCCCTCCTGCACTGGCCCTGCACTACCACCCTGCTGACTATATATAA
GGAAACTAAGGGCCTTAAATGGCCCCTCCTGGCGGCGTTAATCCCTACCGCCATGGGACTTTTAGCCTGCTTCCTGGTAA
AGACGCTGGCAAACCTGGCTGGCCTTTTCTAA

Upstream 100 bases:

>100_bases
TGGAGGGCGATGAGGGGATCTTGATGGCGCTCAAGCAACACCTGGGAATCCCTGTCTCCCAACTAGAAGTTAAGCTGCAG
CTTAAAGGGGTGCCGGCCTG

Downstream 100 bases:

>100_bases
AGAAGACGTGGCTGCAGCCCGCCCCGGGGCCGGCGTTAGTCGCTGCTGTGGCGGAATAACCAGGCCCTCAGGTCCTCCAG
CCTTTCCCCTTCAGGATACT

Product: nucleoside recognition

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 462

Protein sequence:

>463_residues
MANMETRRLLSQARSLTEGLEENLRDRIVTALYARAEGIAARVIKKNPSPRRDWDRRLDTVLTSRLWGYPLMLILLAAVF
WLTVSGANYPSALLGRLLFGFQDILSGLFGRLGAPDWLHGILVLGMYRTLAWVVSVMLPPMAIFFPLFTLLEDLGYLPRV
AFNLDHLFHRAGAHGKQALTMCMGFGCNAAGVVGCRIIESPRERLIAILTNNFAPCNGRFPTLIALATIFLGGLVAPSGR
AAVAALSVAGIVLLGILLMFLTSWLLSRTILKGVPSAFTLELPPYRPPQVLRVIVRSVFDRTLFVLARAVVVAAPAGALT
WALANIHVGGVSIIAHLAGWLQPLGRVVGLDGYILLAFILGLPANEIVIPILLMGYLATGMLTDLDSLAALGSVLTSHGW
TTVTALNMMLFSLLHWPCTTTLLTIYKETKGLKWPLLAALIPTAMGLLACFLVKTLANLAGLF

Sequences:

>Translated_463_residues
MANMETRRLLSQARSLTEGLEENLRDRIVTALYARAEGIAARVIKKNPSPRRDWDRRLDTVLTSRLWGYPLMLILLAAVF
WLTVSGANYPSALLGRLLFGFQDILSGLFGRLGAPDWLHGILVLGMYRTLAWVVSVMLPPMAIFFPLFTLLEDLGYLPRV
AFNLDHLFHRAGAHGKQALTMCMGFGCNAAGVVGCRIIESPRERLIAILTNNFAPCNGRFPTLIALATIFLGGLVAPSGR
AAVAALSVAGIVLLGILLMFLTSWLLSRTILKGVPSAFTLELPPYRPPQVLRVIVRSVFDRTLFVLARAVVVAAPAGALT
WALANIHVGGVSIIAHLAGWLQPLGRVVGLDGYILLAFILGLPANEIVIPILLMGYLATGMLTDLDSLAALGSVLTSHGW
TTVTALNMMLFSLLHWPCTTTLLTIYKETKGLKWPLLAALIPTAMGLLACFLVKTLANLAGLF
>Mature_462_residues
ANMETRRLLSQARSLTEGLEENLRDRIVTALYARAEGIAARVIKKNPSPRRDWDRRLDTVLTSRLWGYPLMLILLAAVFW
LTVSGANYPSALLGRLLFGFQDILSGLFGRLGAPDWLHGILVLGMYRTLAWVVSVMLPPMAIFFPLFTLLEDLGYLPRVA
FNLDHLFHRAGAHGKQALTMCMGFGCNAAGVVGCRIIESPRERLIAILTNNFAPCNGRFPTLIALATIFLGGLVAPSGRA
AVAALSVAGIVLLGILLMFLTSWLLSRTILKGVPSAFTLELPPYRPPQVLRVIVRSVFDRTLFVLARAVVVAAPAGALTW
ALANIHVGGVSIIAHLAGWLQPLGRVVGLDGYILLAFILGLPANEIVIPILLMGYLATGMLTDLDSLAALGSVLTSHGWT
TVTALNMMLFSLLHWPCTTTLLTIYKETKGLKWPLLAALIPTAMGLLACFLVKTLANLAGLF

Specific function: Not involved in Fe(2+) uptake but is involved in manganese uptake. Could be GTP-driven [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=284, Percent_Identity=29.5774647887324, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 50196; Mature: 50065

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ANMETRRLLSQARSLTEGLEENLRDRIVTALYARAEGIAARVIKKNPSPRRDWDRRLDT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH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HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]