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The map label for this gene is csd [H]

Identifier: 83590250

GI number: 83590250

Start: 1450441

End: 1451592

Strand: Reverse

Name: csd [H]

Synonym: Moth_1403

Alternate gene names: 83590250

Gene position: 1451592-1450441 (Counterclockwise)

Preceding gene: 83590252

Following gene: 83590249

Centisome position: 55.22

GC content: 63.19

Gene sequence:

>1152_bases
ATGATTTATCTCAATAATGCCGCCACCTCCTGGCCCAAGCCGGAGACTGTTTACCAGGCCCACGACGCTTATTTGCGCCA
TCTCAGCGGCAGCGTCAACCGCGGCGCCGGCGGGGCCTCCCTGGACGCCGGCCGGGCGGTCCTGGAGACCAGGGAACTCC
TGGCGGATTTCTTTAACATCCGCGAACCGGAGCAGGTCATCTTCACAGCCAACGCCACCGAAGCCCTCAACCTGGCCCTT
CAGGGGTTGCTGGAGCCGGGAGACCACGTGGTTATCAGCAGCCTGGAGCATAATGCCGTGGCGCGGCCCCTGCATACCCT
GCAGGATAAGGGGGTCGAATATACCATCGTCAACTGCGACGCCCGGGGCCGCCTCAATCCTTTAGATGTGGAAAGGGCCA
TCGGCCCCCGGACCAGGTTGATTTGCCTGACCCACGCTTCCAACGTAACCGGCACCATCCTACCTGTCAACGAAGTGGGG
GAGATCGCCCGGCGGCATCATCTCCAGTACCTGGTGGATACGGCCCAGACGGCGGGGGAAATCCCCGTGGATGTGGAGGC
GGCCGGGATTACCCTGCTGGCCTTCACCGGCCACAAGGGCCTGCTGGGCCCACCTGGGACCGGCGGGCTTTATATCCGTT
ACCCCGATACCGTCCGGCCCCTGATTTATGGCGGGACAGGCAGCAGGTCCGAACTCCTCACCCAGCCAGAGGTGCTGCCT
GATAAGTATGAGAGCGGCACCGTCAATGCCCCGGCCATAGCCGCCCTGGGGGCGGGGGTAAGGTTTATCCGGGAGACGGG
CTTGGACAATATCCGCCGCCATACCAGGGAATTGACAGCCCGGCTCCTGGAGGGGTTGCGCCGCCTGCCGGGGGTAACCC
TTTATGGCCCCACGGATTCGGGGGAGCGGGTACCGGTGGTTTCATTAAATATCCGCGGCCTCTCTCCCGGGGAGGCCAGC
GCCTGGCTGGCGGACCACTATGATATTGTCAGCCGCCCGGGGCTCCATTGCGCCCCCCTGGCCCACCAAACCATCGGCAC
CCTTAAGACGGGCACCCTGCGCCTGAGCCCTGGCTTTTTTAATACCGCTGCCGAAATCGATGCCGCCCTGGCAGCAATCA
AAGAACTGATGGAGGTCATGCAGGGTGAATGA

Upstream 100 bases:

>100_bases
CTATGGATACAGGGCAAGCAGGAACAACATAGAATAATATAAAAGGATAACAACCCCGGCCCAGCCCGGGCTGTGGAAGG
AGAAAGCAGAGGAATAATTG

Downstream 100 bases:

>100_bases
ACTGGTTCTTTTGACCTTTCCTTCCACCTTCTACGCCCTCAGGGCGGAAAAGGTTGTCCAGGGGGCCGGCCTCAGGGGCC
GGCTGATCCCCGTGCCCCGG

Product: cysteine desulphurase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MIYLNNAATSWPKPETVYQAHDAYLRHLSGSVNRGAGGASLDAGRAVLETRELLADFFNIREPEQVIFTANATEALNLAL
QGLLEPGDHVVISSLEHNAVARPLHTLQDKGVEYTIVNCDARGRLNPLDVERAIGPRTRLICLTHASNVTGTILPVNEVG
EIARRHHLQYLVDTAQTAGEIPVDVEAAGITLLAFTGHKGLLGPPGTGGLYIRYPDTVRPLIYGGTGSRSELLTQPEVLP
DKYESGTVNAPAIAALGAGVRFIRETGLDNIRRHTRELTARLLEGLRRLPGVTLYGPTDSGERVPVVSLNIRGLSPGEAS
AWLADHYDIVSRPGLHCAPLAHQTIGTLKTGTLRLSPGFFNTAAEIDAALAAIKELMEVMQGE

Sequences:

>Translated_383_residues
MIYLNNAATSWPKPETVYQAHDAYLRHLSGSVNRGAGGASLDAGRAVLETRELLADFFNIREPEQVIFTANATEALNLAL
QGLLEPGDHVVISSLEHNAVARPLHTLQDKGVEYTIVNCDARGRLNPLDVERAIGPRTRLICLTHASNVTGTILPVNEVG
EIARRHHLQYLVDTAQTAGEIPVDVEAAGITLLAFTGHKGLLGPPGTGGLYIRYPDTVRPLIYGGTGSRSELLTQPEVLP
DKYESGTVNAPAIAALGAGVRFIRETGLDNIRRHTRELTARLLEGLRRLPGVTLYGPTDSGERVPVVSLNIRGLSPGEAS
AWLADHYDIVSRPGLHCAPLAHQTIGTLKTGTLRLSPGFFNTAAEIDAALAAIKELMEVMQGE
>Mature_383_residues
MIYLNNAATSWPKPETVYQAHDAYLRHLSGSVNRGAGGASLDAGRAVLETRELLADFFNIREPEQVIFTANATEALNLAL
QGLLEPGDHVVISSLEHNAVARPLHTLQDKGVEYTIVNCDARGRLNPLDVERAIGPRTRLICLTHASNVTGTILPVNEVG
EIARRHHLQYLVDTAQTAGEIPVDVEAAGITLLAFTGHKGLLGPPGTGGLYIRYPDTVRPLIYGGTGSRSELLTQPEVLP
DKYESGTVNAPAIAALGAGVRFIRETGLDNIRRHTRELTARLLEGLRRLPGVTLYGPTDSGERVPVVSLNIRGLSPGEAS
AWLADHYDIVSRPGLHCAPLAHQTIGTLKTGTLRLSPGFFNTAAEIDAALAAIKELMEVMQGE

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=399, Percent_Identity=26.0651629072682, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI156713448, Length=443, Percent_Identity=25.0564334085779, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4557289, Length=312, Percent_Identity=25.3205128205128, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787970, Length=393, Percent_Identity=31.5521628498728, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789175, Length=391, Percent_Identity=29.156010230179, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI48994898, Length=348, Percent_Identity=27.2988505747126, Blast_Score=120, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI25143064, Length=304, Percent_Identity=27.6315789473684, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17533177, Length=250, Percent_Identity=28, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=395, Percent_Identity=27.5949367088608, Blast_Score=140, Evalue=4e-34,
Organism=Drosophila melanogaster, GI20129463, Length=383, Percent_Identity=28.4595300261097, Blast_Score=119, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 41148; Mature: 41148

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYLNNAATSWPKPETVYQAHDAYLRHLSGSVNRGAGGASLDAGRAVLETRELLADFFNI
CEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
REPEQVIFTANATEALNLALQGLLEPGDHVVISSLEHNAVARPLHTLQDKGVEYTIVNCD
CCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECC
ARGRLNPLDVERAIGPRTRLICLTHASNVTGTILPVNEVGEIARRHHLQYLVDTAQTAGE
CCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
IPVDVEAAGITLLAFTGHKGLLGPPGTGGLYIRYPDTVRPLIYGGTGSRSELLTQPEVLP
CCEEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCHHHCCCCCCCC
DKYESGTVNAPAIAALGAGVRFIRETGLDNIRRHTRELTARLLEGLRRLPGVTLYGPTDS
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
GERVPVVSLNIRGLSPGEASAWLADHYDIVSRPGLHCAPLAHQTIGTLKTGTLRLSPGFF
CCEEEEEEEEEECCCCCCCCHHHHHCHHHHCCCCCCCCHHHHHHHCCEECCEEEECCCCC
NTAAEIDAALAAIKELMEVMQGE
CHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIYLNNAATSWPKPETVYQAHDAYLRHLSGSVNRGAGGASLDAGRAVLETRELLADFFNI
CEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCC
REPEQVIFTANATEALNLALQGLLEPGDHVVISSLEHNAVARPLHTLQDKGVEYTIVNCD
CCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECC
ARGRLNPLDVERAIGPRTRLICLTHASNVTGTILPVNEVGEIARRHHLQYLVDTAQTAGE
CCCCCCCCCHHHHCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCC
IPVDVEAAGITLLAFTGHKGLLGPPGTGGLYIRYPDTVRPLIYGGTGSRSELLTQPEVLP
CCEEEEECCEEEEEEECCCCCCCCCCCCCEEEECCCCCCCEEECCCCCCHHHCCCCCCCC
DKYESGTVNAPAIAALGAGVRFIRETGLDNIRRHTRELTARLLEGLRRLPGVTLYGPTDS
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCC
GERVPVVSLNIRGLSPGEASAWLADHYDIVSRPGLHCAPLAHQTIGTLKTGTLRLSPGFF
CCEEEEEEEEEECCCCCCCCHHHHHCHHHHCCCCCCCCHHHHHHHCCEECCEEEECCCCC
NTAAEIDAALAAIKELMEVMQGE
CHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]