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The map label for this gene is hgdC [H]

Identifier: 83590217

GI number: 83590217

Start: 1415708

End: 1416667

Strand: Reverse

Name: hgdC [H]

Synonym: Moth_1370

Alternate gene names: 83590217

Gene position: 1416667-1415708 (Counterclockwise)

Preceding gene: 83590218

Following gene: 83590213

Centisome position: 53.89

GC content: 62.08

Gene sequence:

>960_bases
TTGACCTCTATCTACCTGGGCATCGACGTTGGATCAGTAAGCACCAACGTCATTGCCCTGGATATAGACGGTAACTTACT
CGCCTCCGTCTACCTTCGTACCCGCGGCCAGCCTATCCCGGCCATCCAGGAGGGTTTACGAGAGATTAGGGCTACCCTGG
GCCGAGAGGTGACTGTCGCTGGCGTCGGCACAACAGGCAGCGGCCGGGGCCTGGCGGCCGTCATGACAGGGGCTGATGTC
GTCAAAAACGAAATCACCGCCCATGCCGTAGCTGCCAGCCAGGTCGTACCCGGTGTCCAAACGGTGCTGGAGATCGGCGG
CCAGGACTCTAAAATAATCATCCTGCGCCAGGGCGTAGTCACCGACTTTGCCATGAATACCGTCTGTGCCGCCGGCACCG
GTTCCTTCCTGGACCAGCAGGCGGCCCGTTTGGGGATCCCCATCGAGAATTTCGGTCGCCTGGCCCTGGGTGCCAAGAAC
CCGGTGCGCATCGCTGGGCGCTGCGCCGTCTTTGCCGAATCCGATATGATCCATAAACAGCAACAGGGCCACCCCCTGGA
TGATATCGTCGCCGGCCTGTGCGAGGCCCTGGTACGCAACTACCTGAATAACGTCGGTAAGGGTAAGGAGATCCTGCCGC
CGGTAGTCTTCCAGGGCGGGGTGGCGGCCAACGCCGGTATGCGCCAGGCCTTCAGTCGCGCCCTGGGGACGGAGGTCATC
GTCCCGGAGCATTATGGTGTTATGGGCGCCTACGGGGCCGCCCTCCTGGCCCGGGAAGCCCGCCCGAAAACGAGCGCTTT
CCGGGGCTTTGAGCTTACCGAAAGGGACTTCCGGACCGGCGGTTTTGAATGCCGGGGGTGTGCCAATCACTGCGAAGTGG
TGGAATTAAGGGAAGGAAAAGAGGTCCTGGCCCGCTGGGGCGACCGCTGTGGCAAGTGGAGCAATGCTGTAGCCGTCTAG

Upstream 100 bases:

>100_bases
GGGCGTGAGAGCGGGGTAACAAAGCCCGCCGGGAGAACATTCCCTCCCCGGGAAGCAACATAACGTAATGGGGAAAGCTG
CTGAAAGGAGCTGATCCGAT

Downstream 100 bases:

>100_bases
GTCTAGGTCGCGGTTGGACCAGGGTTTAAATGTCAGTCAACCCCATTTTTATCCTTCCCTGGTGGCGGCAACCTGCAACT
TGTCCGCAGTGGAAGTAATG

Product: CoA enzyme activase

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTSIYLGIDVGSVSTNVIALDIDGNLLASVYLRTRGQPIPAIQEGLREIRATLGREVTVAGVGTTGSGRGLAAVMTGADV
VKNEITAHAVAASQVVPGVQTVLEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIENFGRLALGAKN
PVRIAGRCAVFAESDMIHKQQQGHPLDDIVAGLCEALVRNYLNNVGKGKEILPPVVFQGGVAANAGMRQAFSRALGTEVI
VPEHYGVMGAYGAALLAREARPKTSAFRGFELTERDFRTGGFECRGCANHCEVVELREGKEVLARWGDRCGKWSNAVAV

Sequences:

>Translated_319_residues
MTSIYLGIDVGSVSTNVIALDIDGNLLASVYLRTRGQPIPAIQEGLREIRATLGREVTVAGVGTTGSGRGLAAVMTGADV
VKNEITAHAVAASQVVPGVQTVLEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIENFGRLALGAKN
PVRIAGRCAVFAESDMIHKQQQGHPLDDIVAGLCEALVRNYLNNVGKGKEILPPVVFQGGVAANAGMRQAFSRALGTEVI
VPEHYGVMGAYGAALLAREARPKTSAFRGFELTERDFRTGGFECRGCANHCEVVELREGKEVLARWGDRCGKWSNAVAV
>Mature_318_residues
TSIYLGIDVGSVSTNVIALDIDGNLLASVYLRTRGQPIPAIQEGLREIRATLGREVTVAGVGTTGSGRGLAAVMTGADVV
KNEITAHAVAASQVVPGVQTVLEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIENFGRLALGAKNP
VRIAGRCAVFAESDMIHKQQQGHPLDDIVAGLCEALVRNYLNNVGKGKEILPPVVFQGGVAANAGMRQAFSRALGTEVIV
PEHYGVMGAYGAALLAREARPKTSAFRGFELTERDFRTGGFECRGCANHCEVVELREGKEVLARWGDRCGKWSNAVAV

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=263, Percent_Identity=33.4600760456274, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 33627; Mature: 33496

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIYLGIDVGSVSTNVIALDIDGNLLASVYLRTRGQPIPAIQEGLREIRATLGREVTVA
CCEEEEEEEECCCCCEEEEEEECCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEE
GVGTTGSGRGLAAVMTGADVVKNEITAHAVAASQVVPGVQTVLEIGGQDSKIIILRQGVV
EECCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCH
TDFAMNTVCAAGTGSFLDQQAARLGIPIENFGRLALGAKNPVRIAGRCAVFAESDMIHKQ
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCEEECCCCCEEEEEEEEEEECHHHHHHH
QQGHPLDDIVAGLCEALVRNYLNNVGKGKEILPPVVFQGGVAANAGMRQAFSRALGTEVI
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCEEE
VPEHYGVMGAYGAALLAREARPKTSAFRGFELTERDFRTGGFECRGCANHCEVVELREGK
CCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHCCCCCEECCCCCCCCEEEECCCH
EVLARWGDRCGKWSNAVAV
HHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSIYLGIDVGSVSTNVIALDIDGNLLASVYLRTRGQPIPAIQEGLREIRATLGREVTVA
CEEEEEEEECCCCCEEEEEEECCCEEEHHHHHCCCCCCHHHHHHHHHHHHHHCCEEEEE
GVGTTGSGRGLAAVMTGADVVKNEITAHAVAASQVVPGVQTVLEIGGQDSKIIILRQGVV
EECCCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCEEEEEECCCH
TDFAMNTVCAAGTGSFLDQQAARLGIPIENFGRLALGAKNPVRIAGRCAVFAESDMIHKQ
HHHHHHHHHHCCCCHHHHHHHHHCCCCHHHCCCEEECCCCCEEEEEEEEEEECHHHHHHH
QQGHPLDDIVAGLCEALVRNYLNNVGKGKEILPPVVFQGGVAANAGMRQAFSRALGTEVI
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHCCEEE
VPEHYGVMGAYGAALLAREARPKTSAFRGFELTERDFRTGGFECRGCANHCEVVELREGK
CCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHCCCCCEECCCCCCCCEEEECCCH
EVLARWGDRCGKWSNAVAV
HHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]