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The map label for this gene is pheA [H]

Identifier: 83590181

GI number: 83590181

Start: 1380498

End: 1381340

Strand: Reverse

Name: pheA [H]

Synonym: Moth_1334

Alternate gene names: 83590181

Gene position: 1381340-1380498 (Counterclockwise)

Preceding gene: 83590182

Following gene: 83590180

Centisome position: 52.55

GC content: 59.67

Gene sequence:

>843_bases
ATGAAAGGAATAGCTTATCTTGGCCCCCGGGGGACATACTCCCACGAGGCGGCAACCATCTGGGGGCAGAGGGCAGGCCA
GGACTCCTTCCTGGCCTGCCCCGATTTACCGGGAGTCCTGGCCGCTGTCCTCCAGGGGCAGGCTGCGGCAGCCATATTAC
CAGTAGAAAACTCCATCGAAGGGGCCGTCAACCTCACCCTGGACCTGGTCCTGGAAAACCCGGAACTCCAGGTAATCGGG
GAGGTCGTCCTCCCCGTTCACCACTGTTTAATAAGCCGCGCCGGGGACCTGGCCACAATCCGGGAGGTCTGGTCCCACCC
CCAGGCCCTGGCCCAGTGCCGCCATTACCTGGCCCAAAACTTACCGGGAGTCATAACCCGGCCGGCTACCAGCACGGCTG
CCGCTGCCGATCAGGCCCGGCAACAGCCGTACCTGGCGGCCATCGCTTCTAACTTTGCCGCCGAGGTATACCAGCTGCCG
GTTCTGGCTGCCGGTATTGAAGACTACCCAGATAATAAGACCCGGTTCTGGGTCCTGGGGAGGGAAAACCTCCACCTCCC
AGGACCCTATAAAACCTCCCTGGTGGTAGCGGCAGTGGCCAACAGGCCGGGAAGCCTCTATGCCATTTTAAAGGATTTTG
CCGCAGCAGGCATTAACCTGACAAGGATTGAATCCCGGCCCACCAAACAGGAACTGGGAGAGTACCTGTTTTTTATTGAT
TGCGAGGGCAGGGCCACGGAGCCTCCTTTAAGGGAGGTCCTGGTAGGCCTGAAAGCCAAAACGTCTTTATTATCAATTCT
CGGTTCCTATGCCCGCGATGGGGGTGGGACCAGTGGCCAGTAG

Upstream 100 bases:

>100_bases
ACGGCTCCCAGTCCCTGGACCCGGAACAGTTCGCCGCCCTGGTCAGGGAGATCCGGCCCATCATCACCGCCAGCGGGCGT
GAACTGGAGCGGCAGGCCGT

Downstream 100 bases:

>100_bases
CAAATCTGGTCCCGGGATAGAAAGGGTGGCTATCCTCGGTCTGGGGCTCATCGGCGGCTCCCTGGGCCTGGCCCTCCGCA
AAAGGGGGGTAAAAGAGGTG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKGIAYLGPRGTYSHEAATIWGQRAGQDSFLACPDLPGVLAAVLQGQAAAAILPVENSIEGAVNLTLDLVLENPELQVIG
EVVLPVHHCLISRAGDLATIREVWSHPQALAQCRHYLAQNLPGVITRPATSTAAAADQARQQPYLAAIASNFAAEVYQLP
VLAAGIEDYPDNKTRFWVLGRENLHLPGPYKTSLVVAAVANRPGSLYAILKDFAAAGINLTRIESRPTKQELGEYLFFID
CEGRATEPPLREVLVGLKAKTSLLSILGSYARDGGGTSGQ

Sequences:

>Translated_280_residues
MKGIAYLGPRGTYSHEAATIWGQRAGQDSFLACPDLPGVLAAVLQGQAAAAILPVENSIEGAVNLTLDLVLENPELQVIG
EVVLPVHHCLISRAGDLATIREVWSHPQALAQCRHYLAQNLPGVITRPATSTAAAADQARQQPYLAAIASNFAAEVYQLP
VLAAGIEDYPDNKTRFWVLGRENLHLPGPYKTSLVVAAVANRPGSLYAILKDFAAAGINLTRIESRPTKQELGEYLFFID
CEGRATEPPLREVLVGLKAKTSLLSILGSYARDGGGTSGQ
>Mature_280_residues
MKGIAYLGPRGTYSHEAATIWGQRAGQDSFLACPDLPGVLAAVLQGQAAAAILPVENSIEGAVNLTLDLVLENPELQVIG
EVVLPVHHCLISRAGDLATIREVWSHPQALAQCRHYLAQNLPGVITRPATSTAAAADQARQQPYLAAIASNFAAEVYQLP
VLAAGIEDYPDNKTRFWVLGRENLHLPGPYKTSLVVAAVANRPGSLYAILKDFAAAGINLTRIESRPTKQELGEYLFFID
CEGRATEPPLREVLVGLKAKTSLLSILGSYARDGGGTSGQ

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=273, Percent_Identity=33.3333333333333, Blast_Score=136, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6324013, Length=321, Percent_Identity=27.1028037383178, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 29872; Mature: 29872

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGIAYLGPRGTYSHEAATIWGQRAGQDSFLACPDLPGVLAAVLQGQAAAAILPVENSIE
CCCCEEECCCCCCCCCHHHHHCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCC
GAVNLTLDLVLENPELQVIGEVVLPVHHCLISRAGDLATIREVWSHPQALAQCRHYLAQN
CEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHC
LPGVITRPATSTAAAADQARQQPYLAAIASNFAAEVYQLPVLAAGIEDYPDNKTRFWVLG
CCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
RENLHLPGPYKTSLVVAAVANRPGSLYAILKDFAAAGINLTRIESRPTKQELGEYLFFID
CCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEEE
CEGRATEPPLREVLVGLKAKTSLLSILGSYARDGGGTSGQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKGIAYLGPRGTYSHEAATIWGQRAGQDSFLACPDLPGVLAAVLQGQAAAAILPVENSIE
CCCCEEECCCCCCCCCHHHHHCCCCCCCCEEECCCCHHHHHHHHCCCCCEEEEECCCCCC
GAVNLTLDLVLENPELQVIGEVVLPVHHCLISRAGDLATIREVWSHPQALAQCRHYLAQN
CEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHC
LPGVITRPATSTAAAADQARQQPYLAAIASNFAAEVYQLPVLAAGIEDYPDNKTRFWVLG
CCCEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEE
RENLHLPGPYKTSLVVAAVANRPGSLYAILKDFAAAGINLTRIESRPTKQELGEYLFFID
CCCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHCCEEEEEE
CEGRATEPPLREVLVGLKAKTSLLSILGSYARDGGGTSGQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]