Click here to switch to the map view.

The map label for this gene is plsC [H]

Identifier: 83590177

GI number: 83590177

Start: 1376524

End: 1377105

Strand: Reverse

Name: plsC [H]

Synonym: Moth_1330

Alternate gene names: 83590177

Gene position: 1377105-1376524 (Counterclockwise)

Preceding gene: 83590178

Following gene: 83590176

Centisome position: 52.39

GC content: 56.01

Gene sequence:

>582_bases
TTGTTTTACCAGTTTGCCAAATTTGTCTGCTACTTATTTCTCCGCTTTATATGCCGCTGGGAAGTCCGGGGCCAGGAAAA
CATACCGGCCGAAGGGCCGGTGGTTATCGTCGCAAATCATGTCTCCTACCTGGACCCGGTGGTAGTCGGCGTTGCCTTTC
CGCGAATGGTACGTTTCATGGCCAAAGAGGAGCTTTTCCATATCCCCATCTTCAAGTACATTATAAGGGGCCTGCAGGCG
TTCCCTGTTCGCCGGGGCGAGTCGGACCGTGCGGCCTTGAAAACCGCCCTGCAGATTCTTCACCAGGGCCAGGTCCTGGG
TATATTTCCCGAAGGCACCCGCAGTCCTGACGGCCGCTTACTTCCCTTCCAGGCCGGGGCGGCGGTACTGGCCCTTAAAA
CCGGGGCCGTACTCCTGCCGGTGGCCATTAAAGATACCGACCGGGTCTTTCGCGGCGGCCACATCAAGATAACCTTTGGC
CGTCCCCTGAAAATAACAACCTCCGGGAGAAACTACACTTCCCAGCAAGTTCAGGACCTGACGTCAGCCGCCTACCAGGA
AGTAAAGAAAATGCTGGCTTAA

Upstream 100 bases:

>100_bases
CAGGTAATCCTTTTATAAACGCGTTCGGAAAGATAAGTGCCGGCCGCTAATCGCAAACAATGCCAGCCGATGGCAAAGCT
ATTTCCGGAGGATCCGCCAG

Downstream 100 bases:

>100_bases
AGGCCAGCTTTTTTTAGCGGGAGGCAGGATTTTGCGCCTTTTTCGCGAAATGTAAATAATGTTTGCCTGGAGTCAGCAAA
CTAATTCTTAGCCTGACCAG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferases

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; 1-acyl-G3P acyltransferase; Lysophosphatidic acid acyltransferase; LPAAT; Phosphatidic acid synthase; PA synthase [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MFYQFAKFVCYLFLRFICRWEVRGQENIPAEGPVVIVANHVSYLDPVVVGVAFPRMVRFMAKEELFHIPIFKYIIRGLQA
FPVRRGESDRAALKTALQILHQGQVLGIFPEGTRSPDGRLLPFQAGAAVLALKTGAVLLPVAIKDTDRVFRGGHIKITFG
RPLKITTSGRNYTSQQVQDLTSAAYQEVKKMLA

Sequences:

>Translated_193_residues
MFYQFAKFVCYLFLRFICRWEVRGQENIPAEGPVVIVANHVSYLDPVVVGVAFPRMVRFMAKEELFHIPIFKYIIRGLQA
FPVRRGESDRAALKTALQILHQGQVLGIFPEGTRSPDGRLLPFQAGAAVLALKTGAVLLPVAIKDTDRVFRGGHIKITFG
RPLKITTSGRNYTSQQVQDLTSAAYQEVKKMLA
>Mature_193_residues
MFYQFAKFVCYLFLRFICRWEVRGQENIPAEGPVVIVANHVSYLDPVVVGVAFPRMVRFMAKEELFHIPIFKYIIRGLQA
FPVRRGESDRAALKTALQILHQGQVLGIFPEGTRSPDGRLLPFQAGAAVLALKTGAVLLPVAIKDTDRVFRGGHIKITFG
RPLKITTSGRNYTSQQVQDLTSAAYQEVKKMLA

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cytoplasm. Note=Probably associated with the membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17564032, Length=199, Percent_Identity=28.1407035175879, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568319, Length=147, Percent_Identity=29.2517006802721, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281364648, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582856, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24582854, Length=168, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24641614, Length=163, Percent_Identity=32.5153374233129, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24641612, Length=163, Percent_Identity=32.5153374233129, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: 2.3.1.51

Molecular weight: Translated: 21651; Mature: 21651

Theoretical pI: Translated: 10.53; Mature: 10.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFYQFAKFVCYLFLRFICRWEVRGQENIPAEGPVVIVANHVSYLDPVVVGVAFPRMVRFM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
AKEELFHIPIFKYIIRGLQAFPVRRGESDRAALKTALQILHQGQVLGIFPEGTRSPDGRL
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCE
LPFQAGAAVLALKTGAVLLPVAIKDTDRVFRGGHIKITFGRPLKITTSGRNYTSQQVQDL
EEECCCCEEEEEECCCEEEEEEECCCCHHHCCCEEEEEECCCEEEEECCCCCHHHHHHHH
TSAAYQEVKKMLA
HHHHHHHHHHHHC
>Mature Secondary Structure
MFYQFAKFVCYLFLRFICRWEVRGQENIPAEGPVVIVANHVSYLDPVVVGVAFPRMVRFM
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHH
AKEELFHIPIFKYIIRGLQAFPVRRGESDRAALKTALQILHQGQVLGIFPEGTRSPDGRL
HHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCE
LPFQAGAAVLALKTGAVLLPVAIKDTDRVFRGGHIKITFGRPLKITTSGRNYTSQQVQDL
EEECCCCEEEEEECCCEEEEEEECCCCHHHCCCEEEEEECCCEEEEECCCCCHHHHHHHH
TSAAYQEVKKMLA
HHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]