Click here to switch to the map view.

The map label for this gene is ubiE [H]

Identifier: 83590128

GI number: 83590128

Start: 1321803

End: 1322504

Strand: Reverse

Name: ubiE [H]

Synonym: Moth_1280

Alternate gene names: 83590128

Gene position: 1322504-1321803 (Counterclockwise)

Preceding gene: 83590129

Following gene: 83590127

Centisome position: 50.31

GC content: 59.83

Gene sequence:

>702_bases
ATGACCAAAGAGGAATACGTCCGCGGGATATTTGACACCATTGCTCACCGTTATGACCTTCTAAACACCCTGCTCAGCTT
TAATTGCGACCGGGGCTGGCGGCGTTTTACCGTTGCTCGCACGGGCCTTAAACCCGGTGACAGGGCCCTGGACGTCTGCT
GCGGTACCGGAATGCTTTCCCTGGAGCTGGCGCGGGCAGTCACCCCGGGGGGAAGGGTGGTAGGCGTGGATTTTTCCCCG
GCCATGCTCCAGGTGGCCCGGCGTCGCCTGGCCGCCAGTCCCTACGGCGCAGCGGTGGAACTGGTGGAAGGCAACGCTAT
GAACCTGCCCTTTGCCGATAATACCTTTGATTGCGCGACCATCGCCTTTGGCCTGCGCAATCTCCCCGATGTCAAGGGTG
GCCTGGCGGAGATGCAGCGGGTTGTCCGGCCCGGGGGCCGCGTGGTTTCCCTGGAATTGGCCAAACCATCACGTCCTATT
TTTAAACAGGTCTACTACCTTTATTTCGATCACCTGGTACCCCTCCTGGGACGCCTGGGCATCGGCCAGGACGGGCCCTA
CAGCTACCTGCCCCGGTCCCTCAAGGGTTACCCCCACCAGGAAGAAGTCCTGCAGTATTTTCACGACCTGGGCTTTACCG
GAGCCCGTTATTTTGAATTGACCGGTGGCATCGTAGCCGTCCACGTAGGCGTGAAGGTATAA

Upstream 100 bases:

>100_bases
GGGTCATAGCCGACCTGCCTCCAGGACCGGTACGGGAGGGACTGGGTGAAATCTTTTTATTTTTAAACGGCAGGCTACCT
GTGAAAAAAGTGATGGTTCT

Downstream 100 bases:

>100_bases
AGATAGAAACGCAAGCATTCACGTTGCTTTCCCGGGAGGGTAAGGTTATAATGGGTGTAGCCTGGGGAGGGAGGTGCAGT
AATGGAAGATAAGTCCATGA

Product: demethylmenaquinone methyltransferase / 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MTKEEYVRGIFDTIAHRYDLLNTLLSFNCDRGWRRFTVARTGLKPGDRALDVCCGTGMLSLELARAVTPGGRVVGVDFSP
AMLQVARRRLAASPYGAAVELVEGNAMNLPFADNTFDCATIAFGLRNLPDVKGGLAEMQRVVRPGGRVVSLELAKPSRPI
FKQVYYLYFDHLVPLLGRLGIGQDGPYSYLPRSLKGYPHQEEVLQYFHDLGFTGARYFELTGGIVAVHVGVKV

Sequences:

>Translated_233_residues
MTKEEYVRGIFDTIAHRYDLLNTLLSFNCDRGWRRFTVARTGLKPGDRALDVCCGTGMLSLELARAVTPGGRVVGVDFSP
AMLQVARRRLAASPYGAAVELVEGNAMNLPFADNTFDCATIAFGLRNLPDVKGGLAEMQRVVRPGGRVVSLELAKPSRPI
FKQVYYLYFDHLVPLLGRLGIGQDGPYSYLPRSLKGYPHQEEVLQYFHDLGFTGARYFELTGGIVAVHVGVKV
>Mature_232_residues
TKEEYVRGIFDTIAHRYDLLNTLLSFNCDRGWRRFTVARTGLKPGDRALDVCCGTGMLSLELARAVTPGGRVVGVDFSPA
MLQVARRRLAASPYGAAVELVEGNAMNLPFADNTFDCATIAFGLRNLPDVKGGLAEMQRVVRPGGRVVSLELAKPSRPIF
KQVYYLYFDHLVPLLGRLGIGQDGPYSYLPRSLKGYPHQEEVLQYFHDLGFTGARYFELTGGIVAVHVGVKV

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) [H]

COG id: COG2226

COG function: function code H; Methylase involved in ubiquinone/menaquinone biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI116063536, Length=260, Percent_Identity=32.6923076923077, Blast_Score=152, Evalue=3e-37,
Organism=Escherichia coli, GI48994983, Length=230, Percent_Identity=39.5652173913043, Blast_Score=181, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17557039, Length=232, Percent_Identity=30.6034482758621, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI25143945, Length=157, Percent_Identity=25.4777070063694, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323526, Length=247, Percent_Identity=29.9595141700405, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24641702, Length=246, Percent_Identity=32.9268292682927, Blast_Score=129, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 25699; Mature: 25568

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS01183 UBIE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKEEYVRGIFDTIAHRYDLLNTLLSFNCDRGWRRFTVARTGLKPGDRALDVCCGTGMLS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHHHHHHCCCHHH
LELARAVTPGGRVVGVDFSPAMLQVARRRLAASPYGAAVELVEGNAMNLPFADNTFDCAT
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCHHHH
IAFGLRNLPDVKGGLAEMQRVVRPGGRVVSLELAKPSRPIFKQVYYLYFDHLVPLLGRLG
HHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
IGQDGPYSYLPRSLKGYPHQEEVLQYFHDLGFTGARYFELTGGIVAVHVGVKV
CCCCCCHHHCCHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECC
>Mature Secondary Structure 
TKEEYVRGIFDTIAHRYDLLNTLLSFNCDRGWRRFTVARTGLKPGDRALDVCCGTGMLS
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCHHHHHHHHCCCHHH
LELARAVTPGGRVVGVDFSPAMLQVARRRLAASPYGAAVELVEGNAMNLPFADNTFDCAT
HHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCEEEEECCCEEECCCCCCCCHHHH
IAFGLRNLPDVKGGLAEMQRVVRPGGRVVSLELAKPSRPIFKQVYYLYFDHLVPLLGRLG
HHHHHHCCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
IGQDGPYSYLPRSLKGYPHQEEVLQYFHDLGFTGARYFELTGGIVAVHVGVKV
CCCCCCHHHCCHHHCCCCCHHHHHHHHHHCCCCCCEEEEECCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA