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The map label for this gene is aiiA [H]

Identifier: 83590104

GI number: 83590104

Start: 1298827

End: 1299588

Strand: Reverse

Name: aiiA [H]

Synonym: Moth_1256

Alternate gene names: 83590104

Gene position: 1299588-1298827 (Counterclockwise)

Preceding gene: 83590105

Following gene: 83590101

Centisome position: 49.44

GC content: 49.61

Gene sequence:

>762_bases
ATGGGAATTAACCCCTTACAAGTTGTTGCTCTTAAGATGGGCGAACTCTATGTCGACAAATCGACCCTGACCTATGCCAA
GGACTTCGGTAAAATGATTACCATTCCCATCTGGGCGGCAGCCATTATCGGCGCGGAGGCAAAAATCGTTGTCGACACCG
GCATCCACGACCGGAACTGGGTAAATGAGCACGTGGATCCCTGTCAGCAGCAGGAAGATGAAAAGATGGCTGTAGCTTTG
AAAAAGGCTACCGGATGGGACCCGGAAGAAGTGGATATCGTTATCAATACCCATTTACACTATGACCATGTTGGAAATAA
CCGTATCTTTAAAAATGCCGTTTTCTATGTCCAACAATTGGAATGGGAATATGCCTTCCATCCATTGAAAAGCCAGGAAT
GGATTTACAACGACACCCGCTTCCTTTACGACCAGCGGGGTGTGGACTTCTTCGCCTGGCGATTTGTCAACGGCTATGCC
GATGTGGTCCCCGGGGTCAAACTCATTCCAACCCCCGGGCACACTCCGGGCCACCAGTCGGTACTGGTGAAAACAGCCGA
GGGTGTGGTCTGTGTTTCCGGTGACGTTGTCAACCTGGTAGAAAATATTAATGAGGACCGGCCAGTGGGTATAGTAACCG
ATGTTGGCGCCAACTTTGAAAGCTTTGCCAGAATCCGTCAGTACGCCGATTATATCCTGGCCGGCCATGATCCAGGAATC
CAGAAATTCCAGCGGGAACACTTCCCGGCAATTAAAAAATAA

Upstream 100 bases:

>100_bases
ATGGGAGTAGTATTACAATTGTTTACAGTTGAAAAAGCAGGTATTTTTGCCAAATCGGATGAATCTATCTTCGTTAAGTA
ATTACCGGGAGGCAGTAAGT

Downstream 100 bases:

>100_bases
CGCAAAGGCGTTTTATCCCTTCTCAAACACCTCGTCCGCCAGGGAGCGGACTTCTTTTTTGCGCCTGGCGGTGGCTTCCG
GGTCCAAGACGACGGCAAGC

Product: Beta-lactamase-like

Products: NA

Alternate protein names: AHL-lactonase AiiA [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MGINPLQVVALKMGELYVDKSTLTYAKDFGKMITIPIWAAAIIGAEAKIVVDTGIHDRNWVNEHVDPCQQQEDEKMAVAL
KKATGWDPEEVDIVINTHLHYDHVGNNRIFKNAVFYVQQLEWEYAFHPLKSQEWIYNDTRFLYDQRGVDFFAWRFVNGYA
DVVPGVKLIPTPGHTPGHQSVLVKTAEGVVCVSGDVVNLVENINEDRPVGIVTDVGANFESFARIRQYADYILAGHDPGI
QKFQREHFPAIKK

Sequences:

>Translated_253_residues
MGINPLQVVALKMGELYVDKSTLTYAKDFGKMITIPIWAAAIIGAEAKIVVDTGIHDRNWVNEHVDPCQQQEDEKMAVAL
KKATGWDPEEVDIVINTHLHYDHVGNNRIFKNAVFYVQQLEWEYAFHPLKSQEWIYNDTRFLYDQRGVDFFAWRFVNGYA
DVVPGVKLIPTPGHTPGHQSVLVKTAEGVVCVSGDVVNLVENINEDRPVGIVTDVGANFESFARIRQYADYILAGHDPGI
QKFQREHFPAIKK
>Mature_252_residues
GINPLQVVALKMGELYVDKSTLTYAKDFGKMITIPIWAAAIIGAEAKIVVDTGIHDRNWVNEHVDPCQQQEDEKMAVALK
KATGWDPEEVDIVINTHLHYDHVGNNRIFKNAVFYVQQLEWEYAFHPLKSQEWIYNDTRFLYDQRGVDFFAWRFVNGYAD
VVPGVKLIPTPGHTPGHQSVLVKTAEGVVCVSGDVVNLVENINEDRPVGIVTDVGANFESFARIRQYADYILAGHDPGIQ
KFQREHFPAIKK

Specific function: Catalyzes hydrolysis of N-hexanoyl-(S)-homoserine lactone, but not the R-enantiomer. Hydrolyzes short- and long- chain N-acyl homoserine lactones with or without 3-oxo substitution at C3, has maximum activity on C10-AHL [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: =3.1.1.81 [H]

Molecular weight: Translated: 28651; Mature: 28520

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGINPLQVVALKMGELYVDKSTLTYAKDFGKMITIPIWAAAIIGAEAKIVVDTGIHDRNW
CCCCHHHHHEEECCCEEECCCHHHHHHHCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCC
VNEHVDPCQQQEDEKMAVALKKATGWDPEEVDIVINTHLHYDHVGNNRIFKNAVFYVQQL
CHHHCCHHHHHCCCHHHEEEECCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHH
EWEYAFHPLKSQEWIYNDTRFLYDQRGVDFFAWRFVNGYADVVPGVKLIPTPGHTPGHQS
HHHHHCCCCCCCCEEECCCEEEEECCCCEEEEEEHHCCHHHHCCCCEEEECCCCCCCCCE
VLVKTAEGVVCVSGDVVNLVENINEDRPVGIVTDVGANFESFARIRQYADYILAGHDPGI
EEEEECCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCCCH
QKFQREHFPAIKK
HHHHHHCCCCCCC
>Mature Secondary Structure 
GINPLQVVALKMGELYVDKSTLTYAKDFGKMITIPIWAAAIIGAEAKIVVDTGIHDRNW
CCCHHHHHEEECCCEEECCCHHHHHHHCCCEEEHHHHHHHHHCCCEEEEEECCCCCCCC
VNEHVDPCQQQEDEKMAVALKKATGWDPEEVDIVINTHLHYDHVGNNRIFKNAVFYVQQL
CHHHCCHHHHHCCCHHHEEEECCCCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHH
EWEYAFHPLKSQEWIYNDTRFLYDQRGVDFFAWRFVNGYADVVPGVKLIPTPGHTPGHQS
HHHHHCCCCCCCCEEECCCEEEEECCCCEEEEEEHHCCHHHHCCCCEEEECCCCCCCCCE
VLVKTAEGVVCVSGDVVNLVENINEDRPVGIVTDVGANFESFARIRQYADYILAGHDPGI
EEEEECCCEEEECCHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHEEECCCCCH
QKFQREHFPAIKK
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11916693; 12147491 [H]