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The map label for this gene is mtaD [H]

Identifier: 83590072

GI number: 83590072

Start: 1261375

End: 1262700

Strand: Reverse

Name: mtaD [H]

Synonym: Moth_1224

Alternate gene names: 83590072

Gene position: 1262700-1261375 (Counterclockwise)

Preceding gene: 83590073

Following gene: 83590071

Centisome position: 48.03

GC content: 58.45

Gene sequence:

>1326_bases
ATGACTATATTAATCAAAAACGGCACCCTGGTCACCATGAACCCCCAGCGGGAGGTGTATCAGGGAAACATCTATATTGA
AGACGATCGCATTGCCGCCATCGGCCAGACGCCGGCCACCGCCGACCGGATCATCGAGGCTAAGGGCCAGTTAGTCATCC
CCGGCCTCGTCCAGCCCCATATCCACCTCTGTCAGACCCTCTTCCGCGGCCGCGCCGACGACCTGGAACTCCTGGACTGG
TTGCGCCTGCGTATCTGGCCCCTGGAGGGTGCCCACGATCCCGAGTCCCTTTATTACTCCGCCCTCCTCGGCATAGGTGA
ACTCTTCCTGAGCGGGACCACTACCATCGTGGATATGGAAACCGTCCACCATACAGAGGCAGCCATCGAGGCCATCGCCC
AAAGCGGCATCCGAGCCATCACCGGCAAAGTGATGATGGATTTTGGCGAAGACGTTCCGGAGACCCTCAGGGAAACCACG
GAGGCATCCCTGCAGGAGAGCGTCCAATTGCTTGAGAAGTGGCACGGGCACGATAACGGCCGCATCCAGTACGCCTTCGA
GCCCCGCTTTGTGGTCTCCTGTACCGAGGAATTATTATTAAAGGTCCGGGATCTCGCCCGCAAGTACGGTGTTAAAATCC
ATACCCACGCCTCGGAAAACTTGGGTGAATGCGCCCTGGTGGAAAAGCTCCACCACCGGCGTAACGTCCTCTATCTTGAC
GATATCGGCCTCACCGGCCCCGGCCTCATCCTTGTCCACTGCATCTGGCTCGATGAAGAAGAGAAAGATATTCTGGCTCG
CACTGGTACCAAGGTGGTTCATTGCCCTTCCTCTAACTTAAAGATGGCTTCCGGTATCTGCCCCGTACCGGATCTTTTGA
GCCGGGGGACGGTGGTTTCCCTGGCCGCCGATGGCGCGCCCTGCAATAACAACCTGGACGCTTTCATGGAAATGCGGCTG
GCGGCGCTAATTCAAAAGCCTGTCCACGGCCCTACGTCCATGCCGGCGTCTGTAATCTTTGAAATGGCCACCCTGGGTGG
GGCCCGAGCCATGGGAATGGAAAAGGAAATCGGCAGCCTGGAAGTGGGGAAGAAGGCTGACCTGGCCCTGGTCTCCGTGG
ATGGCCTCCATACCCAGCCAGAAGACGGCGTTAACGTCTACACCCAGCTGGTCTACCAGGCTAAAGGGTCGGACGTCACC
CTGACCATGGTCGACGGCAAAATCGTCATGGAGAAGGGCGAACTGAAGACCATAGATGTCGATGAAGTCCGGCGGAAGGC
CAACCAGGCCATCCAGCGTGTCGCCCACAGAGCCGGGCTGGCTTAG

Upstream 100 bases:

>100_bases
TTAACGCTATCTACGATGCTATCGGCGTCCGCATTACCGAGCTACCGGCTACACCGGAAAAAATTTTGGCCGCACTGCGG
GCAAAAGAAGGAGAGAGACA

Downstream 100 bases:

>100_bases
CTTTTTAATACACATATAATCTGAATTAGTACCCCTGGACATCCTACCCAGGTTATGATAAAATAGCCTTAAAATGAATA
TGTTCCAGGCAAATACGGGA

Product: N-ethylammeline chlorohydrolase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 441; Mature: 440

Protein sequence:

>441_residues
MTILIKNGTLVTMNPQREVYQGNIYIEDDRIAAIGQTPATADRIIEAKGQLVIPGLVQPHIHLCQTLFRGRADDLELLDW
LRLRIWPLEGAHDPESLYYSALLGIGELFLSGTTTIVDMETVHHTEAAIEAIAQSGIRAITGKVMMDFGEDVPETLRETT
EASLQESVQLLEKWHGHDNGRIQYAFEPRFVVSCTEELLLKVRDLARKYGVKIHTHASENLGECALVEKLHHRRNVLYLD
DIGLTGPGLILVHCIWLDEEEKDILARTGTKVVHCPSSNLKMASGICPVPDLLSRGTVVSLAADGAPCNNNLDAFMEMRL
AALIQKPVHGPTSMPASVIFEMATLGGARAMGMEKEIGSLEVGKKADLALVSVDGLHTQPEDGVNVYTQLVYQAKGSDVT
LTMVDGKIVMEKGELKTIDVDEVRRKANQAIQRVAHRAGLA

Sequences:

>Translated_441_residues
MTILIKNGTLVTMNPQREVYQGNIYIEDDRIAAIGQTPATADRIIEAKGQLVIPGLVQPHIHLCQTLFRGRADDLELLDW
LRLRIWPLEGAHDPESLYYSALLGIGELFLSGTTTIVDMETVHHTEAAIEAIAQSGIRAITGKVMMDFGEDVPETLRETT
EASLQESVQLLEKWHGHDNGRIQYAFEPRFVVSCTEELLLKVRDLARKYGVKIHTHASENLGECALVEKLHHRRNVLYLD
DIGLTGPGLILVHCIWLDEEEKDILARTGTKVVHCPSSNLKMASGICPVPDLLSRGTVVSLAADGAPCNNNLDAFMEMRL
AALIQKPVHGPTSMPASVIFEMATLGGARAMGMEKEIGSLEVGKKADLALVSVDGLHTQPEDGVNVYTQLVYQAKGSDVT
LTMVDGKIVMEKGELKTIDVDEVRRKANQAIQRVAHRAGLA
>Mature_440_residues
TILIKNGTLVTMNPQREVYQGNIYIEDDRIAAIGQTPATADRIIEAKGQLVIPGLVQPHIHLCQTLFRGRADDLELLDWL
RLRIWPLEGAHDPESLYYSALLGIGELFLSGTTTIVDMETVHHTEAAIEAIAQSGIRAITGKVMMDFGEDVPETLRETTE
ASLQESVQLLEKWHGHDNGRIQYAFEPRFVVSCTEELLLKVRDLARKYGVKIHTHASENLGECALVEKLHHRRNVLYLDD
IGLTGPGLILVHCIWLDEEEKDILARTGTKVVHCPSSNLKMASGICPVPDLLSRGTVVSLAADGAPCNNNLDAFMEMRLA
ALIQKPVHGPTSMPASVIFEMATLGGARAMGMEKEIGSLEVGKKADLALVSVDGLHTQPEDGVNVYTQLVYQAKGSDVTL
TMVDGKIVMEKGELKTIDVDEVRRKANQAIQRVAHRAGLA

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Homo sapiens, GI4758426, Length=335, Percent_Identity=30.7462686567164, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1789249, Length=399, Percent_Identity=32.3308270676692, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082177, Length=462, Percent_Identity=25.3246753246753, Blast_Score=99, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17540282, Length=408, Percent_Identity=23.2843137254902, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6319963, Length=354, Percent_Identity=28.8135593220339, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24643849, Length=390, Percent_Identity=29.2307692307692, Blast_Score=150, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 48412; Mature: 48281

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILIKNGTLVTMNPQREVYQGNIYIEDDRIAAIGQTPATADRIIEAKGQLVIPGLVQPH
CEEEEECCEEEEECCCCCEEECCEEEECCCEEEECCCCCHHHHHHHCCCCEEECCCCCHH
IHLCQTLFRGRADDLELLDWLRLRIWPLEGAHDPESLYYSALLGIGELFLSGTTTIVDME
HHHHHHHHCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEH
TVHHTEAAIEAIAQSGIRAITGKVMMDFGEDVPETLRETTEASLQESVQLLEKWHGHDNG
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RIQYAFEPRFVVSCTEELLLKVRDLARKYGVKIHTHASENLGECALVEKLHHRRNVLYLD
EEEEEECCCEEEHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
DIGLTGPGLILVHCIWLDEEEKDILARTGTKVVHCPSSNLKMASGICPVPDLLSRGTVVS
CCCCCCCCEEEEEEEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHCCCCEEE
LAADGAPCNNNLDAFMEMRLAALIQKPVHGPTSMPASVIFEMATLGGARAMGMEKEIGSL
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHCCCHHCCCCC
EVGKKADLALVSVDGLHTQPEDGVNVYTQLVYQAKGSDVTLTMVDGKIVMEKGELKTIDV
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHEECCCEEEEEEECCEEEEECCCEEEECH
DEVRRKANQAIQRVAHRAGLA
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TILIKNGTLVTMNPQREVYQGNIYIEDDRIAAIGQTPATADRIIEAKGQLVIPGLVQPH
EEEEECCEEEEECCCCCEEECCEEEECCCEEEECCCCCHHHHHHHCCCCEEECCCCCHH
IHLCQTLFRGRADDLELLDWLRLRIWPLEGAHDPESLYYSALLGIGELFLSGTTTIVDME
HHHHHHHHCCCCCCHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEH
TVHHTEAAIEAIAQSGIRAITGKVMMDFGEDVPETLRETTEASLQESVQLLEKWHGHDNG
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RIQYAFEPRFVVSCTEELLLKVRDLARKYGVKIHTHASENLGECALVEKLHHRRNVLYLD
EEEEEECCCEEEHHHHHHHHHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHCCEEEEE
DIGLTGPGLILVHCIWLDEEEKDILARTGTKVVHCPSSNLKMASGICPVPDLLSRGTVVS
CCCCCCCCEEEEEEEECCCCCHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHCCCCEEE
LAADGAPCNNNLDAFMEMRLAALIQKPVHGPTSMPASVIFEMATLGGARAMGMEKEIGSL
EEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHCCCHHCCCCC
EVGKKADLALVSVDGLHTQPEDGVNVYTQLVYQAKGSDVTLTMVDGKIVMEKGELKTIDV
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHEECCCEEEEEEECCEEEEECCCEEEECH
DEVRRKANQAIQRVAHRAGLA
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA