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The map label for this gene is cbiJ [H]

Identifier: 83590071

GI number: 83590071

Start: 1259921

End: 1260715

Strand: Reverse

Name: cbiJ [H]

Synonym: Moth_1223

Alternate gene names: 83590071

Gene position: 1260715-1259921 (Counterclockwise)

Preceding gene: 83590072

Following gene: 161611346

Centisome position: 47.96

GC content: 53.84

Gene sequence:

>795_bases
TTGATTTTGGTGGTAGGGAGTACCGGGGAGGGAAGGCAGTTAACCCGCAGCCTCCGGGAGGCCGGTTATCAAATTGTAAC
CTGGGCTGACAGTACCTACGGAGAGCAGCTGGCCCGGCAGGATGGGGCGGTAGCAATATTAACAGGTCCTTTTACGGAGG
ATAATCTAGCTGCCCTGGAGAGTAACAGGCAGTTGGAAGCAGTCATTGATGCCACCCTACCTTATCCCAACCATATATCC
CGGACCCTGGAAGCCTGGTGCCGGCAACAACAGATATATTACCTGCGTTTTTTACGTGCCGAGACAAGGCTGCCGGATGA
CAATCTCATCTATCAGGTGGCCACCTGGGACGAAGCCGCTCGAACAGCCGCACGGCTGGGAGAGACCATTTTTTTAACAA
CCGGTACCAATAACCTGGAAGTTTTCGTCAAAAACCCGCTGCTAAAAGGCAAGCGAATCGTGGTCCGGGTATTACCTGAA
CACCAGGTAATTAAAAAATGCCAGGACTTGGGCTTGACGCCCCGCGACATTATCGCCATGCAGGGGCCTTTCTCCAAAGA
AATAAATAAAGCCATGTTTAAAGCCTGCAAGGCTGGCGTCGTCGTCACCCGCGATGCCGGCCCGGCTGGCGGCACCGAGG
CCAAAATCGCCGCCGCCCTGGCGCTAAAAATACCGGTAGTAGTAATCAAGCGGCCTGCCATTCAGTACCGTTACCCTGTC
TATACAGCTTCTGAAGCCGTCGCCCTGCTGCAAAAGATAGCGCCTCCGCAATTAGATGTGGGAAATGAGACGTGA

Upstream 100 bases:

>100_bases
GGGAGGTGGTGTATTGAGGCATGCCTGTTTGACGGCAGCACCATTCGCTCCCCGGCATTATTGCCGGGGATTTTAGTTTT
CGCAAGGAGGGCATGGCCTC

Downstream 100 bases:

>100_bases
AGGGGGTACATACGATGTTCCGCCGTACAACCTGGTTAACACTGTATCTTCTCCTGGCTATGGCCGCGCTGGCCCGGCCG
GCCTTTGCCATGCATATCGC

Product: precorrin-6A reductase

Products: Precorrin 6A; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MILVVGSTGEGRQLTRSLREAGYQIVTWADSTYGEQLARQDGAVAILTGPFTEDNLAALESNRQLEAVIDATLPYPNHIS
RTLEAWCRQQQIYYLRFLRAETRLPDDNLIYQVATWDEAARTAARLGETIFLTTGTNNLEVFVKNPLLKGKRIVVRVLPE
HQVIKKCQDLGLTPRDIIAMQGPFSKEINKAMFKACKAGVVVTRDAGPAGGTEAKIAAALALKIPVVVIKRPAIQYRYPV
YTASEAVALLQKIAPPQLDVGNET

Sequences:

>Translated_264_residues
MILVVGSTGEGRQLTRSLREAGYQIVTWADSTYGEQLARQDGAVAILTGPFTEDNLAALESNRQLEAVIDATLPYPNHIS
RTLEAWCRQQQIYYLRFLRAETRLPDDNLIYQVATWDEAARTAARLGETIFLTTGTNNLEVFVKNPLLKGKRIVVRVLPE
HQVIKKCQDLGLTPRDIIAMQGPFSKEINKAMFKACKAGVVVTRDAGPAGGTEAKIAAALALKIPVVVIKRPAIQYRYPV
YTASEAVALLQKIAPPQLDVGNET
>Mature_264_residues
MILVVGSTGEGRQLTRSLREAGYQIVTWADSTYGEQLARQDGAVAILTGPFTEDNLAALESNRQLEAVIDATLPYPNHIS
RTLEAWCRQQQIYYLRFLRAETRLPDDNLIYQVATWDEAARTAARLGETIFLTTGTNNLEVFVKNPLLKGKRIVVRVLPE
HQVIKKCQDLGLTPRDIIAMQGPFSKEINKAMFKACKAGVVVTRDAGPAGGTEAKIAAALALKIPVVVIKRPAIQYRYPV
YTASEAVALLQKIAPPQLDVGNET

Specific function: Catalyzes the reduction of the macrocycle of cobalt- precorrin-6X into cobalt-precorrin-6Y [H]

COG id: COG2099

COG function: function code H; Precorrin-6x reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin-6x reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003723 [H]

Pfam domain/function: PF02571 CbiJ [H]

EC number: 1.3.1.54

Molecular weight: Translated: 29074; Mature: 29074

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS51014 COBK_CBIJ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVVGSTGEGRQLTRSLREAGYQIVTWADSTYGEQLARQDGAVAILTGPFTEDNLAALE
CEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHH
SNRQLEAVIDATLPYPNHISRTLEAWCRQQQIYYLRFLRAETRLPDDNLIYQVATWDEAA
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
RTAARLGETIFLTTGTNNLEVFVKNPLLKGKRIVVRVLPEHQVIKKCQDLGLTPRDIIAM
HHHHHCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHEEE
QGPFSKEINKAMFKACKAGVVVTRDAGPAGGTEAKIAAALALKIPVVVIKRPAIQYRYPV
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEECCE
YTASEAVALLQKIAPPQLDVGNET
EEHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MILVVGSTGEGRQLTRSLREAGYQIVTWADSTYGEQLARQDGAVAILTGPFTEDNLAALE
CEEEEECCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCEEEEECCCCCCCHHHHH
SNRQLEAVIDATLPYPNHISRTLEAWCRQQQIYYLRFLRAETRLPDDNLIYQVATWDEAA
CCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHH
RTAARLGETIFLTTGTNNLEVFVKNPLLKGKRIVVRVLPEHQVIKKCQDLGLTPRDIIAM
HHHHHCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCHHHHEEE
QGPFSKEINKAMFKACKAGVVVTRDAGPAGGTEAKIAAALALKIPVVVIKRPAIQYRYPV
CCCCHHHHHHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCEEEECCE
YTASEAVALLQKIAPPQLDVGNET
EEHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 6B; NADP+

Specific reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]