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The map label for this gene is hgdC [H]

Identifier: 83589997

GI number: 83589997

Start: 1180172

End: 1181134

Strand: Reverse

Name: hgdC [H]

Synonym: Moth_1149

Alternate gene names: 83589997

Gene position: 1181134-1180172 (Counterclockwise)

Preceding gene: 83589998

Following gene: 83589996

Centisome position: 44.93

GC content: 57.74

Gene sequence:

>963_bases
ATGCAGCCCTGTTACCTGGGTATTGATGTCGGTTCCGTCAGCACCAACGTGGTAGTCATTAGCGCCACAGGAGAGATTTT
AAGCAGCCTGTATTTAAGGACCCACGGCCAGCCTATCCAGGCCATCAAGGAGGGCCTGCGCCAGACGATGGCAGCCCTCC
CCGGGGATGTCGAGATAGCCGGAGCCGGTACTACCGGCAGCGGCCGCACCCTGGCGGGAGCAATTATCGGCGCAGATATT
ATCAAAAACGAAATTACCGCCCATGCCGTCGCTTCCCGCCAGGAGGTCCCGGATGTCCAGACCATCCTGGAGATTGGGGG
CCAGGACTCGAAGATTATCATCCTACGCCAGGGAGTAGTTACCGATTTTGCCATGAATACCGTCTGTGCCGCCGGTACAG
GGTCCTTTCTGGATCAACAGGCGGCCCGGCTGGGGATTCCCATTGAACACTTCGGCGACCTGGCTCTAAAATCCCGCAAC
CCGGTGCGTATTGCCGGCAGGTGTACGGTCTTTGCCGAGTCCGATATGATTCATAAACAGCAGATGGGGCACAATACAGA
AGATATCATTGGCGGGCTGTGTGAGGCCCTGGTTCGCAACTACCTGAACAATGTCGCCAAAGGTAAGGAGATCCTGCCGC
CCATTGTCTTCCAGGGCGGGGTGGCTGCCAATGCCGGAATCCGGGCTGCCTTCGCCAAGGCCTTGGGGCAGGAGATCATC
GTTCCCCGTCACTTTGCCGTTATGGGCGCCCTGGGGGCAGCCCTCCTGGCCCGGGATTATGTAGCCAAACACCCGGGAAC
AAGATTCAAGGGCTTTGAGGTTTCCGAGGAGGACTACCAGGCCCGGAGTTTTATCTGCCAGGGATGTTCCAACCTGTGTG
AAATTGTCAACATCGAAGCCGACGGGCAGTTAATTGCCCGCTGGGGCAGTCGCTGTGGCAAATGGGATACCCTGGGTGAA
TGA

Upstream 100 bases:

>100_bases
ACCATTGATGAGCAAACCGGCCGGGCCGGGGTGGAGACCCGGCTGGAAGCCTTTGTCGATCTTTTACGCCAGCGTCGCGA
GCAAATGGAGGCAAGGAGTA

Downstream 100 bases:

>100_bases
AAGGAGTAATGCTGTATGCGCGAGAGCACCTTTTCCTTCTGGCAGGATACCAATTTCAATGCCCTGCCCGACCAGCCCTT
GAGTGCTGCCGGCAATGCCT

Product: CoA enzyme activase

Products: NA

Alternate protein names: 2-hydroxyglutaryl-CoA dehydratase component A [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MQPCYLGIDVGSVSTNVVVISATGEILSSLYLRTHGQPIQAIKEGLRQTMAALPGDVEIAGAGTTGSGRTLAGAIIGADI
IKNEITAHAVASRQEVPDVQTILEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIEHFGDLALKSRN
PVRIAGRCTVFAESDMIHKQQMGHNTEDIIGGLCEALVRNYLNNVAKGKEILPPIVFQGGVAANAGIRAAFAKALGQEII
VPRHFAVMGALGAALLARDYVAKHPGTRFKGFEVSEEDYQARSFICQGCSNLCEIVNIEADGQLIARWGSRCGKWDTLGE

Sequences:

>Translated_320_residues
MQPCYLGIDVGSVSTNVVVISATGEILSSLYLRTHGQPIQAIKEGLRQTMAALPGDVEIAGAGTTGSGRTLAGAIIGADI
IKNEITAHAVASRQEVPDVQTILEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIEHFGDLALKSRN
PVRIAGRCTVFAESDMIHKQQMGHNTEDIIGGLCEALVRNYLNNVAKGKEILPPIVFQGGVAANAGIRAAFAKALGQEII
VPRHFAVMGALGAALLARDYVAKHPGTRFKGFEVSEEDYQARSFICQGCSNLCEIVNIEADGQLIARWGSRCGKWDTLGE
>Mature_320_residues
MQPCYLGIDVGSVSTNVVVISATGEILSSLYLRTHGQPIQAIKEGLRQTMAALPGDVEIAGAGTTGSGRTLAGAIIGADI
IKNEITAHAVASRQEVPDVQTILEIGGQDSKIIILRQGVVTDFAMNTVCAAGTGSFLDQQAARLGIPIEHFGDLALKSRN
PVRIAGRCTVFAESDMIHKQQMGHNTEDIIGGLCEALVRNYLNNVAKGKEILPPIVFQGGVAANAGIRAAFAKALGQEII
VPRHFAVMGALGAALLARDYVAKHPGTRFKGFEVSEEDYQARSFICQGCSNLCEIVNIEADGQLIARWGSRCGKWDTLGE

Specific function: Required for the activation of (R)-2-hydroxyglutaryl-CoA dehydratase. This protein is extremely sensitive towards oxygen [H]

COG id: COG1924

COG function: function code I; Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yjiL and M.jannaschii MJ0004 and MJ0800 [H]

Homologues:

Organism=Escherichia coli, GI87082426, Length=261, Percent_Identity=34.4827586206897, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002731
- InterPro:   IPR008275 [H]

Pfam domain/function: PF01869 BcrAD_BadFG [H]

EC number: NA

Molecular weight: Translated: 33895; Mature: 33895

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPCYLGIDVGSVSTNVVVISATGEILSSLYLRTHGQPIQAIKEGLRQTMAALPGDVEIA
CCCEEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
GAGTTGSGRTLAGAIIGADIIKNEITAHAVASRQEVPDVQTILEIGGQDSKIIILRQGVV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCH
TDFAMNTVCAAGTGSFLDQQAARLGIPIEHFGDLALKSRNPVRIAGRCTVFAESDMIHKQ
HHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCHHCCCCCCEEEEEEEEEEECCHHHHHH
QMGHNTEDIIGGLCEALVRNYLNNVAKGKEILPPIVFQGGVAANAGIRAAFAKALGQEII
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCHHHHHHHHHHCHHCC
VPRHFAVMGALGAALLARDYVAKHPGTRFKGFEVSEEDYQARSFICQGCSNLCEIVNIEA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
DGQLIARWGSRCGKWDTLGE
CCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MQPCYLGIDVGSVSTNVVVISATGEILSSLYLRTHGQPIQAIKEGLRQTMAALPGDVEIA
CCCEEEEEEECCCCCCEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEE
GAGTTGSGRTLAGAIIGADIIKNEITAHAVASRQEVPDVQTILEIGGQDSKIIILRQGVV
ECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCH
TDFAMNTVCAAGTGSFLDQQAARLGIPIEHFGDLALKSRNPVRIAGRCTVFAESDMIHKQ
HHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHCCHHCCCCCCEEEEEEEEEEECCHHHHHH
QMGHNTEDIIGGLCEALVRNYLNNVAKGKEILPPIVFQGGVAANAGIRAAFAKALGQEII
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHCCCCCCCCCHHHHHHHHHHCHHCC
VPRHFAVMGALGAALLARDYVAKHPGTRFKGFEVSEEDYQARSFICQGCSNLCEIVNIEA
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEECCC
DGQLIARWGSRCGKWDTLGE
CCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8365476; 2659350; 7607244; 11106419; 11243821 [H]