| Definition | Moorella thermoacetica ATCC 39073, complete genome. |
|---|---|
| Accession | NC_007644 |
| Length | 2,628,784 |
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The map label for this gene is nrdZ [H]
Identifier: 83589985
GI number: 83589985
Start: 1164651
End: 1166948
Strand: Reverse
Name: nrdZ [H]
Synonym: Moth_1137
Alternate gene names: 83589985
Gene position: 1166948-1164651 (Counterclockwise)
Preceding gene: 83589986
Following gene: 83589983
Centisome position: 44.39
GC content: 55.35
Gene sequence:
>2298_bases ATGAAAATTACCGACAATGCCCGGACTATCCTCGAAAAACGCTACCTGAAGAAAGAAAACGGCGTTCCGGTGGAAACACC GGAAGAGATGTTCCGCCGGGTAGCAGCAGCAGTGGCAGGGGCCGAAAGGATTTTTAATCCCGCCCTCACAGAAGCTCAGG TGGAAGAATATGCCGACCGCTTCTACCGGCTCATGACCAGTTGGGACTTTCTCCCCAACAGCCCGACCTTGATGAATGCC GGCCGGGAGCTGGGCCAACTCTCGGCTTGTTTTGTGTTACCCGTGGATGACAGCATGGATGCCATTTTTACGGCTGTGAA GGATGCGGCCCTGATTCATAAGAGCGGGGGAGGGACAGGCTTTTCCTTTAGCCGTCTGCGTCCCAAGAACAGTCCTGTCC GCTCCACCGGCGGTGTCGCCTCTGGTCCTGTGTCCTTTATGAAGGTCTTTAATGCTGCCACCGAAGCCATTAAGCAGGGA GGGACCAGACGGGGGGCCAACATGGGCATCCTGCGGGTTGATCACCCAGACATCCTGGAGTTTATCTCCTGCAAAGAAAA TAACAATGAACTGACTAACTTTAACATCTCTGTAGGCCTGACCAGGGAATTCATGGACGCCCTGGCCCGGGACGATTACT ATGAACTAAAATTCGAAGGCCGGGTGTATCAAAGGTTAAAAGCGCAAGAGGTATTTGCCGAGATTGTCAACCATGCCTGG GCGAACGGGGAGCCGGGCATCATCTTTTTGGACCGCCTCAATGAGGATAATCCCACCCCCGAGCTGGGCGAAATCGAGGC TACCAACCCCTGTGGTGAACAACCGCTCCTCCCCTACGAGGCCTGTAACCTTGGCTCCGTGAACCTGGCTAATATGGTCC GGGATGGGGGAGTTAACTGGGACAAGCTGGCCGATACGGTCCGCCTGGCGGTACGCTTCCTGGACAATGTCATTGAGATT AATGAGTTCCCCCTGGAAAAGATTAGCGTCATGGTCCGAGGAAATCGCAAGATCGGCCTGGGGGTCATGGGGTGGGCCGA TATGCTCTTCCAGCTCCGGCTACCCTACGATTCCGAAGAAGCCGTGGAACTGGGCCGTAAAGTTATGGCCTTTATCCAGA AGGAGGCCCATGGAGCTTCCCGGGATCTGGCGGGCGAGCGAGGCAGCTTCCCGAACATTGATAAAAGCATTTACCGGGGG CAACAGCTCCGCAACGCCACCTGCACCACCATTGCCCCGACCGGTACCATCAGTATGATTGCCGGCACCACTTCGGGTAT TGAACCTGTCTTTGCCCTGGCTTATACCAAAAACGTACTGGACGGGGCCAGCCTGGTAGAAGTAAATCCTGTTTTCCAGG CTTATGTCGAAGAAAACTTTCCTCCGGAACAAGCCCGGTCGATTTTTAATCGCATCGCCGCCGGTGCCAGGGTTAGTGAA ATTGAATATATCCCGCCGGAGATGCGCCGGGTGTTTGTTACCGCCCTGGAGATCAGCCCGGAATGGCATATACGTATGCA AGCAGCCTTCCAGGCCAGTACTGATAACGCCGTTTCCAAAACAGTTAACTTCCCCTCCGAGGCCACCAGGGAGGATGTGC GCCGAGCCTATGAACTGGCCTATCAGCTGGGATGCAAAGGCGTTACCGTTTACCGCTCCGGCAGCCGGGAAAAGGAGGTC CTGATTACAGGGGCTAAAAATAAACCTGTCAGGGATAGGGAACCGGCCAGGGAGAAAACCTATCCCCGGCCGCGGCCCAA GCGTACCTGTGGTGTCACCGAGCAGGTGAAGACCGGATGCGGTAAAATGTACATTACCGTCAATTATGATCGTGAAGGTT TAATCGAAACCTTTGCCACCACCGGTTCCTCCGGCGGCTGCAGTGGTTTTACCGAAGGTGTCAGCCGGCTTATTTCCCTG GCCCTGCGGGCCAACATCGCCCCGGAGGCCATAATCGACCAGCTTACTTCCGTCAGTTGTCCTAACTTTTTACGCCGCCG GGCCACCGATAAAAGTATAATTGGCAAGTCTTGCCCGGATATCATCGGCCGCGTCCTGGCCCGGGAGTTGAAAAACTGGC ACGACCACGGTCCCTATCAGGTACCTCCCGATTTCAGCGATAAAGCCCTGGCCGAAATTAGTGCCACCGCCGATGCTGCG ACTCCGGTTCTAAATCCCCTGAGCGCCGCCGAGGAGGCCGAGCTTATCGCCAGGGGTATCTGCCCCGAATGTGGCTCAAC CCTCTATTTCCAGGAAGGTTGTGTTACCTGTAGCTGCGGTTTCAGTAAATGCGGTTAA
Upstream 100 bases:
>100_bases CAGCATCCATTTACCTGCATCTTAAAAACTGGAACCAGTGGATAAAGTGGATAACATTGTAGATAACTTCTATTGATGTC ATATTATGGATGGTGGAGAA
Downstream 100 bases:
>100_bases AAAACGGCCCCTTAAGGCCGTAATAGAGTTCCCGCTAACTGGGATTTAAATAGTGAAGGGCTTTAGCCGTTATAAGAACT AACATGTACAACCTGGTAAC
Product: ribonucleotide-diphosphate reductase subunit alpha
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 765; Mature: 765
Protein sequence:
>765_residues MKITDNARTILEKRYLKKENGVPVETPEEMFRRVAAAVAGAERIFNPALTEAQVEEYADRFYRLMTSWDFLPNSPTLMNA GRELGQLSACFVLPVDDSMDAIFTAVKDAALIHKSGGGTGFSFSRLRPKNSPVRSTGGVASGPVSFMKVFNAATEAIKQG GTRRGANMGILRVDHPDILEFISCKENNNELTNFNISVGLTREFMDALARDDYYELKFEGRVYQRLKAQEVFAEIVNHAW ANGEPGIIFLDRLNEDNPTPELGEIEATNPCGEQPLLPYEACNLGSVNLANMVRDGGVNWDKLADTVRLAVRFLDNVIEI NEFPLEKISVMVRGNRKIGLGVMGWADMLFQLRLPYDSEEAVELGRKVMAFIQKEAHGASRDLAGERGSFPNIDKSIYRG QQLRNATCTTIAPTGTISMIAGTTSGIEPVFALAYTKNVLDGASLVEVNPVFQAYVEENFPPEQARSIFNRIAAGARVSE IEYIPPEMRRVFVTALEISPEWHIRMQAAFQASTDNAVSKTVNFPSEATREDVRRAYELAYQLGCKGVTVYRSGSREKEV LITGAKNKPVRDREPAREKTYPRPRPKRTCGVTEQVKTGCGKMYITVNYDREGLIETFATTGSSGGCSGFTEGVSRLISL ALRANIAPEAIIDQLTSVSCPNFLRRRATDKSIIGKSCPDIIGRVLARELKNWHDHGPYQVPPDFSDKALAEISATADAA TPVLNPLSAAEEAELIARGICPECGSTLYFQEGCVTCSCGFSKCG
Sequences:
>Translated_765_residues MKITDNARTILEKRYLKKENGVPVETPEEMFRRVAAAVAGAERIFNPALTEAQVEEYADRFYRLMTSWDFLPNSPTLMNA GRELGQLSACFVLPVDDSMDAIFTAVKDAALIHKSGGGTGFSFSRLRPKNSPVRSTGGVASGPVSFMKVFNAATEAIKQG GTRRGANMGILRVDHPDILEFISCKENNNELTNFNISVGLTREFMDALARDDYYELKFEGRVYQRLKAQEVFAEIVNHAW ANGEPGIIFLDRLNEDNPTPELGEIEATNPCGEQPLLPYEACNLGSVNLANMVRDGGVNWDKLADTVRLAVRFLDNVIEI NEFPLEKISVMVRGNRKIGLGVMGWADMLFQLRLPYDSEEAVELGRKVMAFIQKEAHGASRDLAGERGSFPNIDKSIYRG QQLRNATCTTIAPTGTISMIAGTTSGIEPVFALAYTKNVLDGASLVEVNPVFQAYVEENFPPEQARSIFNRIAAGARVSE IEYIPPEMRRVFVTALEISPEWHIRMQAAFQASTDNAVSKTVNFPSEATREDVRRAYELAYQLGCKGVTVYRSGSREKEV LITGAKNKPVRDREPAREKTYPRPRPKRTCGVTEQVKTGCGKMYITVNYDREGLIETFATTGSSGGCSGFTEGVSRLISL ALRANIAPEAIIDQLTSVSCPNFLRRRATDKSIIGKSCPDIIGRVLARELKNWHDHGPYQVPPDFSDKALAEISATADAA TPVLNPLSAAEEAELIARGICPECGSTLYFQEGCVTCSCGFSKCG >Mature_765_residues MKITDNARTILEKRYLKKENGVPVETPEEMFRRVAAAVAGAERIFNPALTEAQVEEYADRFYRLMTSWDFLPNSPTLMNA GRELGQLSACFVLPVDDSMDAIFTAVKDAALIHKSGGGTGFSFSRLRPKNSPVRSTGGVASGPVSFMKVFNAATEAIKQG GTRRGANMGILRVDHPDILEFISCKENNNELTNFNISVGLTREFMDALARDDYYELKFEGRVYQRLKAQEVFAEIVNHAW ANGEPGIIFLDRLNEDNPTPELGEIEATNPCGEQPLLPYEACNLGSVNLANMVRDGGVNWDKLADTVRLAVRFLDNVIEI NEFPLEKISVMVRGNRKIGLGVMGWADMLFQLRLPYDSEEAVELGRKVMAFIQKEAHGASRDLAGERGSFPNIDKSIYRG QQLRNATCTTIAPTGTISMIAGTTSGIEPVFALAYTKNVLDGASLVEVNPVFQAYVEENFPPEQARSIFNRIAAGARVSE IEYIPPEMRRVFVTALEISPEWHIRMQAAFQASTDNAVSKTVNFPSEATREDVRRAYELAYQLGCKGVTVYRSGSREKEV LITGAKNKPVRDREPAREKTYPRPRPKRTCGVTEQVKTGCGKMYITVNYDREGLIETFATTGSSGGCSGFTEGVSRLISL ALRANIAPEAIIDQLTSVSCPNFLRRRATDKSIIGKSCPDIIGRVLARELKNWHDHGPYQVPPDFSDKALAEISATADAA TPVLNPLSAAEEAELIARGICPECGSTLYFQEGCVTCSCGFSKCG
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-cone domain [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=579, Percent_Identity=28.1519861830743, Blast_Score=202, Evalue=1e-51, Organism=Escherichia coli, GI1789030, Length=587, Percent_Identity=27.2572402044293, Blast_Score=137, Evalue=3e-33, Organism=Escherichia coli, GI2367133, Length=530, Percent_Identity=23.9622641509434, Blast_Score=111, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17555242, Length=586, Percent_Identity=28.4982935153584, Blast_Score=198, Evalue=9e-51, Organism=Saccharomyces cerevisiae, GI6320914, Length=579, Percent_Identity=28.1519861830743, Blast_Score=182, Evalue=1e-46, Organism=Saccharomyces cerevisiae, GI6322123, Length=569, Percent_Identity=26.3620386643234, Blast_Score=177, Evalue=4e-45, Organism=Drosophila melanogaster, GI17352481, Length=577, Percent_Identity=27.9029462738302, Blast_Score=198, Evalue=1e-50,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005144 - InterPro: IPR013344 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 [H]
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 84183; Mature: 84183
Theoretical pI: Translated: 5.71; Mature: 5.71
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.2 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 2.2 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 4.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKITDNARTILEKRYLKKENGVPVETPEEMFRRVAAAVAGAERIFNPALTEAQVEEYADR CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH FYRLMTSWDFLPNSPTLMNAGRELGQLSACFVLPVDDSMDAIFTAVKDAALIHKSGGGTG HHHHHHHCCCCCCCCHHHHCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCC FSFSRLRPKNSPVRSTGGVASGPVSFMKVFNAATEAIKQGGTRRGANMGILRVDHPDILE CCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHH FISCKENNNELTNFNISVGLTREFMDALARDDYYELKFEGRVYQRLKAQEVFAEIVNHAW HHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC ANGEPGIIFLDRLNEDNPTPELGEIEATNPCGEQPLLPYEACNLGSVNLANMVRDGGVNW CCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCCCH DKLADTVRLAVRFLDNVIEINEFPLEKISVMVRGNRKIGLGVMGWADMLFQLRLPYDSEE HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHEECCCCCHH AVELGRKVMAFIQKEAHGASRDLAGERGSFPNIDKSIYRGQQLRNATCTTIAPTGTISMI HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCEEEE AGTTSGIEPVFALAYTKNVLDGASLVEVNPVFQAYVEENFPPEQARSIFNRIAAGARVSE ECCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHCCCEECC IEYIPPEMRRVFVTALEISPEWHIRMQAAFQASTDNAVSKTVNFPSEATREDVRRAYELA CCCCCHHHHHHHHHHEEECCCEEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHH YQLGCKGVTVYRSGSREKEVLITGAKNKPVRDREPAREKTYPRPRPKRTCGVTEQVKTGC HHHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHCCC GKMYITVNYDREGLIETFATTGSSGGCSGFTEGVSRLISLALRANIAPEAIIDQLTSVSC CEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC PNFLRRRATDKSIIGKSCPDIIGRVLARELKNWHDHGPYQVPPDFSDKALAEISATADAA HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH TPVLNPLSAAEEAELIARGICPECGSTLYFQEGCVTCSCGFSKCG HHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCCC >Mature Secondary Structure MKITDNARTILEKRYLKKENGVPVETPEEMFRRVAAAVAGAERIFNPALTEAQVEEYADR CCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH FYRLMTSWDFLPNSPTLMNAGRELGQLSACFVLPVDDSMDAIFTAVKDAALIHKSGGGTG HHHHHHHCCCCCCCCHHHHCCHHHCCCEEEEEEECCCCHHHHHHHHHHHHHEEECCCCCC FSFSRLRPKNSPVRSTGGVASGPVSFMKVFNAATEAIKQGGTRRGANMGILRVDHPDILE CCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHH FISCKENNNELTNFNISVGLTREFMDALARDDYYELKFEGRVYQRLKAQEVFAEIVNHAW HHHCCCCCCCEEEEEEEECCHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHC ANGEPGIIFLDRLNEDNPTPELGEIEATNPCGEQPLLPYEACNLGSVNLANMVRDGGVNW CCCCCCEEEEEECCCCCCCCCCCCEECCCCCCCCCCCCHHCCCCCCCHHHHHHHCCCCCH DKLADTVRLAVRFLDNVIEINEFPLEKISVMVRGNRKIGLGVMGWADMLFQLRLPYDSEE HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEHHHHHHHHHHEECCCCCHH AVELGRKVMAFIQKEAHGASRDLAGERGSFPNIDKSIYRGQQLRNATCTTIAPTGTISMI HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCEEEE AGTTSGIEPVFALAYTKNVLDGASLVEVNPVFQAYVEENFPPEQARSIFNRIAAGARVSE ECCCCCCCHHHHHHHHHHHCCCCCEEEECHHHHHHHHCCCCHHHHHHHHHHHHCCCEECC IEYIPPEMRRVFVTALEISPEWHIRMQAAFQASTDNAVSKTVNFPSEATREDVRRAYELA CCCCCHHHHHHHHHHEEECCCEEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHHH YQLGCKGVTVYRSGSREKEVLITGAKNKPVRDREPAREKTYPRPRPKRTCGVTEQVKTGC HHHCCCCEEEEECCCCCCEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHCCC GKMYITVNYDREGLIETFATTGSSGGCSGFTEGVSRLISLALRANIAPEAIIDQLTSVSC CEEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC PNFLRRRATDKSIIGKSCPDIIGRVLARELKNWHDHGPYQVPPDFSDKALAEISATADAA HHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH TPVLNPLSAAEEAELIARGICPECGSTLYFQEGCVTCSCGFSKCG HHHCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]