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The map label for this gene is hyuA [H]

Identifier: 83589839

GI number: 83589839

Start: 1017408

End: 1019081

Strand: Reverse

Name: hyuA [H]

Synonym: Moth_0990

Alternate gene names: 83589839

Gene position: 1019081-1017408 (Counterclockwise)

Preceding gene: 83589844

Following gene: 83589838

Centisome position: 38.77

GC content: 60.45

Gene sequence:

>1674_bases
ATGTATGTAGGCCTGGATATGGGTGGTACCCATACCGATGTCGTCCTCATAGCCGACGGCCGGGTGCAACGCTACTGCAA
GACACCGACCGACCCTGAAGATTACCTCCATACCGTTACCAGGGCCCTGGACGAGGTCCTGGAGGATGTTGCAACCGGCG
ATGTACAGCGCCTGAACCTCAGCACCACTGTCTGCACCAATGCCATCGTGACCGGCAGGACCAGCCCGGTAGGCTTGCTC
CTGGAACCGGGGCCGGGATTAAATCCCGCCGGGCTGACCTGCGGCGCTAAAAATTTTATCCTCTCGGGCGCCATCGATCA
TCGCGGTCGCCCTACCTCTTCCCTGGTAGCAACCGAAATCGAAGCTGCCGATAAAGAGCTAAGGAAAGCAGCCATCCGTC
ACCTGGCCATAGTAGGTAAGTTTTCCACCCGCAACCCGGAACATGAATTGCAGATCAAGGAAGCCCTTTCCCCGACCTAT
GACTTTATCACCCTGGGCCATCGCCTGTCGGGACGTTTGAACTACCCCAGGCGGGTTTTTACCGCCTATCTGAACAGTGC
CGTAGCATCTATCTATGATGCCTTTGCCACCGCCATAAATGCCTATGCCGATGGCAGGCAACTGCCAGTAGTACCGGATA
TACTAAAAGCCGATGGTGGCACCCTCTCCCTGGCCGCATCCCGGTCCCTCCCGGTGGAGACCATCCTCTCCGGTCCCTCG
GCCAGTATTATGGGAGCCCTGGCCCTGGCGCCCTCTTCCCGGGATACTATTATTCTCGATATCGGCGGTACGACCACTGA
TATCGCCTTCCTGGCCGACGGTGTCCCCCTCTTTGAACCTTTAGGCATAACCCTGGCCGGTTACCCAACCCTGGTACGCG
CCCTTTACAGTTATTCCTTGGGTCTGGGCGGCGACAGCTGCCTGCGGGTCAGGGACGGGCGCCTGAGCATCGGTCCGGAG
CGCCTGGGGCCGGCCCTGGCCCTGGGCGGCCCCGCCCCTACTCCCACCGACGCCCTGATTACCATGGGCCGCCTGGACCT
GGGGGATAAAGGGGCTGCCCGCCGGGGCCTGGATCAGTTAGGGGATCAACTGGGCCTCAATACCGGGGAGGTGGCTAATG
CCATTATCAAACAAATGGCCGGCGAGATTGCCCGCCAGACCCGGGCCCTCCTTGAGAGAATTAATAGCCGCCCGGTATAT
ACCGTGCGGGAAGTCCTGGAGGACAAAAAACTACGCCCGGAACAGGTAATCGTCATCGGTGCCCCGGCGCCCCTCCTGGC
GGCCGAGCTGGAAGCCGCTTTCGGCCTCCCGGTGGTAGCACCCTCCCTGGCCGGGGTTGCCAATGCCATTGGCGCCGCCC
TGAGCCAGCCCACTACGGAAATCACCCTCCAGGCCGATACAGAGCAGGGCTTCCTGACGATTCCCGAAGAGGGCATCAGG
GAGAAAGTCCAACGCGGTTTCAACCTGGAGGCAGCCCGCCAGCGGGCCCTGGCAGCCCTGCAGGATCGCCTGCGGCGCCT
GGCACCGGCGGCAGCCGGTTCCGAATTGGAAGTAGTTGAGGAACAATCCTTTAACATGGTCTCCGGCTTTTATACCACGG
GCAAAAACATCAGAGTCAAAGTCCAGGTTAAACCCCAGGTCAGCCCCCTGGAGGGAGGTGAGCATAATGTATAA

Upstream 100 bases:

>100_bases
AATTATAACCTTTTTATACCAGTTGCCCTGCATCCGGCATTGCCCGGAAGACTTGCAACCTTTGGCCTACAGGTCTAAAA
TAAAACGGGAGGCGAGGCAA

Downstream 100 bases:

>100_bases
AGCCAAGCGCCGCCTGGGCCTGGTTTTCTTCCCTGCCTTTGACTGGGCCATCAGCCCTACCCACCCTGAGCGGGAAGAGC
GCCTCCTCTATACCCAGGAC

Product: hydantoinase/oxoprolinase

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MYVGLDMGGTHTDVVLIADGRVQRYCKTPTDPEDYLHTVTRALDEVLEDVATGDVQRLNLSTTVCTNAIVTGRTSPVGLL
LEPGPGLNPAGLTCGAKNFILSGAIDHRGRPTSSLVATEIEAADKELRKAAIRHLAIVGKFSTRNPEHELQIKEALSPTY
DFITLGHRLSGRLNYPRRVFTAYLNSAVASIYDAFATAINAYADGRQLPVVPDILKADGGTLSLAASRSLPVETILSGPS
ASIMGALALAPSSRDTIILDIGGTTTDIAFLADGVPLFEPLGITLAGYPTLVRALYSYSLGLGGDSCLRVRDGRLSIGPE
RLGPALALGGPAPTPTDALITMGRLDLGDKGAARRGLDQLGDQLGLNTGEVANAIIKQMAGEIARQTRALLERINSRPVY
TVREVLEDKKLRPEQVIVIGAPAPLLAAELEAAFGLPVVAPSLAGVANAIGAALSQPTTEITLQADTEQGFLTIPEEGIR
EKVQRGFNLEAARQRALAALQDRLRRLAPAAAGSELEVVEEQSFNMVSGFYTTGKNIRVKVQVKPQVSPLEGGEHNV

Sequences:

>Translated_557_residues
MYVGLDMGGTHTDVVLIADGRVQRYCKTPTDPEDYLHTVTRALDEVLEDVATGDVQRLNLSTTVCTNAIVTGRTSPVGLL
LEPGPGLNPAGLTCGAKNFILSGAIDHRGRPTSSLVATEIEAADKELRKAAIRHLAIVGKFSTRNPEHELQIKEALSPTY
DFITLGHRLSGRLNYPRRVFTAYLNSAVASIYDAFATAINAYADGRQLPVVPDILKADGGTLSLAASRSLPVETILSGPS
ASIMGALALAPSSRDTIILDIGGTTTDIAFLADGVPLFEPLGITLAGYPTLVRALYSYSLGLGGDSCLRVRDGRLSIGPE
RLGPALALGGPAPTPTDALITMGRLDLGDKGAARRGLDQLGDQLGLNTGEVANAIIKQMAGEIARQTRALLERINSRPVY
TVREVLEDKKLRPEQVIVIGAPAPLLAAELEAAFGLPVVAPSLAGVANAIGAALSQPTTEITLQADTEQGFLTIPEEGIR
EKVQRGFNLEAARQRALAALQDRLRRLAPAAAGSELEVVEEQSFNMVSGFYTTGKNIRVKVQVKPQVSPLEGGEHNV
>Mature_557_residues
MYVGLDMGGTHTDVVLIADGRVQRYCKTPTDPEDYLHTVTRALDEVLEDVATGDVQRLNLSTTVCTNAIVTGRTSPVGLL
LEPGPGLNPAGLTCGAKNFILSGAIDHRGRPTSSLVATEIEAADKELRKAAIRHLAIVGKFSTRNPEHELQIKEALSPTY
DFITLGHRLSGRLNYPRRVFTAYLNSAVASIYDAFATAINAYADGRQLPVVPDILKADGGTLSLAASRSLPVETILSGPS
ASIMGALALAPSSRDTIILDIGGTTTDIAFLADGVPLFEPLGITLAGYPTLVRALYSYSLGLGGDSCLRVRDGRLSIGPE
RLGPALALGGPAPTPTDALITMGRLDLGDKGAARRGLDQLGDQLGLNTGEVANAIIKQMAGEIARQTRALLERINSRPVY
TVREVLEDKKLRPEQVIVIGAPAPLLAAELEAAFGLPVVAPSLAGVANAIGAALSQPTTEITLQADTEQGFLTIPEEGIR
EKVQRGFNLEAARQRALAALQDRLRRLAPAAAGSELEVVEEQSFNMVSGFYTTGKNIRVKVQVKPQVSPLEGGEHNV

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI133901900, Length=384, Percent_Identity=24.21875, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 58963; Mature: 58963

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYVGLDMGGTHTDVVLIADGRVQRYCKTPTDPEDYLHTVTRALDEVLEDVATGDVQRLNL
CEEEECCCCCCEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
STTVCTNAIVTGRTSPVGLLLEPGPGLNPAGLTCGAKNFILSGAIDHRGRPTSSLVATEI
HHHHHHCCEEECCCCCCEEEECCCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHH
EAADKELRKAAIRHLAIVGKFSTRNPEHELQIKEALSPTYDFITLGHRLSGRLNYPRRVF
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCHHHHHHCHHHCCCCCCHHHHH
TAYLNSAVASIYDAFATAINAYADGRQLPVVPDILKADGGTLSLAASRSLPVETILSGPS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHCCCC
ASIMGALALAPSSRDTIILDIGGTTTDIAFLADGVPLFEPLGITLAGYPTLVRALYSYSL
HHHHHHHEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHC
GLGGDSCLRVRDGRLSIGPERLGPALALGGPAPTPTDALITMGRLDLGDKGAARRGLDQL
CCCCCCEEEEECCCCCCCHHHHCCEEEECCCCCCCCHHHEEECCCCCCCCCHHHHHHHHH
GDQLGLNTGEVANAIIKQMAGEIARQTRALLERINSRPVYTVREVLEDKKLRPEQVIVIG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEE
APAPLLAAELEAAFGLPVVAPSLAGVANAIGAALSQPTTEITLQADTEQGFLTIPEEGIR
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCHHHHH
EKVQRGFNLEAARQRALAALQDRLRRLAPAAAGSELEVVEEQSFNMVSGFYTTGKNIRVK
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCEEEEEEECCCCEEEE
VQVKPQVSPLEGGEHNV
EEECCCCCCCCCCCCCC
>Mature Secondary Structure
MYVGLDMGGTHTDVVLIADGRVQRYCKTPTDPEDYLHTVTRALDEVLEDVATGDVQRLNL
CEEEECCCCCCEEEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
STTVCTNAIVTGRTSPVGLLLEPGPGLNPAGLTCGAKNFILSGAIDHRGRPTSSLVATEI
HHHHHHCCEEECCCCCCEEEECCCCCCCCCCCCCCCCHHEEECCCCCCCCCCHHHHHHHH
EAADKELRKAAIRHLAIVGKFSTRNPEHELQIKEALSPTYDFITLGHRLSGRLNYPRRVF
HHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCCCHHHHHHCHHHCCCCCCHHHHH
TAYLNSAVASIYDAFATAINAYADGRQLPVVPDILKADGGTLSLAASRSLPVETILSGPS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCEEEEEECCCCCHHHHHCCCC
ASIMGALALAPSSRDTIILDIGGTTTDIAFLADGVPLFEPLGITLAGYPTLVRALYSYSL
HHHHHHHEECCCCCCEEEEECCCCCHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHC
GLGGDSCLRVRDGRLSIGPERLGPALALGGPAPTPTDALITMGRLDLGDKGAARRGLDQL
CCCCCCEEEEECCCCCCCHHHHCCEEEECCCCCCCCHHHEEECCCCCCCCCHHHHHHHHH
GDQLGLNTGEVANAIIKQMAGEIARQTRALLERINSRPVYTVREVLEDKKLRPEQVIVIG
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEE
APAPLLAAELEAAFGLPVVAPSLAGVANAIGAALSQPTTEITLQADTEQGFLTIPEEGIR
CCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCHHHHH
EKVQRGFNLEAARQRALAALQDRLRRLAPAAAGSELEVVEEQSFNMVSGFYTTGKNIRVK
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHCCCCEEEEEEECCCCEEEE
VQVKPQVSPLEGGEHNV
EEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]