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The map label for this gene is 83589838

Identifier: 83589838

GI number: 83589838

Start: 1016102

End: 1017415

Strand: Reverse

Name: 83589838

Synonym: Moth_0989

Alternate gene names: NA

Gene position: 1017415-1016102 (Counterclockwise)

Preceding gene: 83589839

Following gene: 83589789

Centisome position: 38.7

GC content: 57.23

Gene sequence:

>1314_bases
ATGTATAAAGCCAAGCGCCGCCTGGGCCTGGTTTTCTTCCCTGCCTTTGACTGGGCCATCAGCCCTACCCACCCTGAGCG
GGAAGAGCGCCTCCTCTATACCCAGGACCAGGTGTTCGAAGAAGGCATCCTGGACATCGAAGGCATCAGGGAATATCGCC
CTCGCCTGGCCAGTACCGGCGATGTAGAGCGGGTGCATATCTGTGTGCCGGATGTCCAATCCCGGACGACGGAATCCCAC
CTCATTGCCGCCGGCGGGGCCATTGTTGCCGCTGAAGCCGTTTTAAAGGGAGAAGTAGATAAGGCCTTTGCCATTATCCG
GCCGCCGGGGCATCACTCCTTCCGCATCGTCCATGGCGCCAGGGGTTTTTGTAATATAAATATGGAGGCCATTATGCTTG
AGTATATTCGCCGGCATTACGGCCCCAAACGGATAGCCATTGTCGATACCGACTGCCACCATGGGGACGGCAGCCAGGAT
ATCTACTGGCACGACAAGGATACCCTTTATATCTCCCTACACCAGGACGGCCGTACCCTTTTCCCGGGTACCGGCTTCCT
GAACGAATTCGGCGGCCCCAATGCCTTCGGCTATACCCTTAACCTTCCCCTGCCCCCTGACACCGGGGAAGAGGGGTTCC
TTTATGCCCTGGAACATTTTATCCTGCCGGTGCTAGCCGAATTTAAGCCGGATCTGGTCATCAACTCCGCCGGCCAGGAT
AACCATTATACCGACCCGATAACCAACATGCGTTTTTCAGCCCAGGGTTACGCCCGCCTTAACGACCGCCTGCAACCGGA
TATCGCCGTCCTGGAGGGAGGTTATTCCATCGAAGGCGCCCTGCCCTACGTCAACGCAGGCATTATCCTGGCCCTGGCCG
GCCTCGATTACTCAAGGGTCCGCGAACCTGACTACACTCCGGAAAAGGTGGCTCAATCGCCCCGCGTCAGTGAGTATATC
GCCCGCCTCTGCGACGAGTCCTACCAGGCCTGGCAGCAGAGGGATACCCTCCGGGAAGAGTATATCCGGGGTAAAAAAGA
AATCAGCCGCCGGCGCCGTATTTTCTACGACACCGAGGGGCTGATGGAAACCCAGCAAGAAACGACCCGCGTTTGCCATG
ATTGCGGCGGCGTGACCTGGATTGATTCCCGTACCGACCAGGGCCGCCACATTCTGGCCATCTTTATACCTCGGGACGCC
TGTCCCCGCTGCCAGGAAGAAGGCCATGCCCTCTTTGAAAGCAGCCAGACCATTGATTACCCGGACGGAGTCTTTCTCCA
GGACCGTTTGGAAGATAAGTTGTTCAAGAAATAA

Upstream 100 bases:

>100_bases
TCCTTTAACATGGTCTCCGGCTTTTATACCACGGGCAAAAACATCAGAGTCAAAGTCCAGGTTAAACCCCAGGTCAGCCC
CCTGGAGGGAGGTGAGCATA

Downstream 100 bases:

>100_bases
TTCTAGAGCCGGGGATGAAAACCCCCGGCTTTTTGCTGATTTGAACCCCCCCTGCCCTCACGGCATTCGGTGACACATGG
TGCTGCCTATTGGGAAGAGC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MYKAKRRLGLVFFPAFDWAISPTHPEREERLLYTQDQVFEEGILDIEGIREYRPRLASTGDVERVHICVPDVQSRTTESH
LIAAGGAIVAAEAVLKGEVDKAFAIIRPPGHHSFRIVHGARGFCNINMEAIMLEYIRRHYGPKRIAIVDTDCHHGDGSQD
IYWHDKDTLYISLHQDGRTLFPGTGFLNEFGGPNAFGYTLNLPLPPDTGEEGFLYALEHFILPVLAEFKPDLVINSAGQD
NHYTDPITNMRFSAQGYARLNDRLQPDIAVLEGGYSIEGALPYVNAGIILALAGLDYSRVREPDYTPEKVAQSPRVSEYI
ARLCDESYQAWQQRDTLREEYIRGKKEISRRRRIFYDTEGLMETQQETTRVCHDCGGVTWIDSRTDQGRHILAIFIPRDA
CPRCQEEGHALFESSQTIDYPDGVFLQDRLEDKLFKK

Sequences:

>Translated_437_residues
MYKAKRRLGLVFFPAFDWAISPTHPEREERLLYTQDQVFEEGILDIEGIREYRPRLASTGDVERVHICVPDVQSRTTESH
LIAAGGAIVAAEAVLKGEVDKAFAIIRPPGHHSFRIVHGARGFCNINMEAIMLEYIRRHYGPKRIAIVDTDCHHGDGSQD
IYWHDKDTLYISLHQDGRTLFPGTGFLNEFGGPNAFGYTLNLPLPPDTGEEGFLYALEHFILPVLAEFKPDLVINSAGQD
NHYTDPITNMRFSAQGYARLNDRLQPDIAVLEGGYSIEGALPYVNAGIILALAGLDYSRVREPDYTPEKVAQSPRVSEYI
ARLCDESYQAWQQRDTLREEYIRGKKEISRRRRIFYDTEGLMETQQETTRVCHDCGGVTWIDSRTDQGRHILAIFIPRDA
CPRCQEEGHALFESSQTIDYPDGVFLQDRLEDKLFKK
>Mature_437_residues
MYKAKRRLGLVFFPAFDWAISPTHPEREERLLYTQDQVFEEGILDIEGIREYRPRLASTGDVERVHICVPDVQSRTTESH
LIAAGGAIVAAEAVLKGEVDKAFAIIRPPGHHSFRIVHGARGFCNINMEAIMLEYIRRHYGPKRIAIVDTDCHHGDGSQD
IYWHDKDTLYISLHQDGRTLFPGTGFLNEFGGPNAFGYTLNLPLPPDTGEEGFLYALEHFILPVLAEFKPDLVINSAGQD
NHYTDPITNMRFSAQGYARLNDRLQPDIAVLEGGYSIEGALPYVNAGIILALAGLDYSRVREPDYTPEKVAQSPRVSEYI
ARLCDESYQAWQQRDTLREEYIRGKKEISRRRRIFYDTEGLMETQQETTRVCHDCGGVTWIDSRTDQGRHILAIFIPRDA
CPRCQEEGHALFESSQTIDYPDGVFLQDRLEDKLFKK

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795204, Length=252, Percent_Identity=34.1269841269841, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI17158039, Length=252, Percent_Identity=34.1269841269841, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI30795202, Length=252, Percent_Identity=34.1269841269841, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI13128864, Length=206, Percent_Identity=38.3495145631068, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI20070354, Length=210, Percent_Identity=38.0952380952381, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI148539870, Length=272, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI153085395, Length=243, Percent_Identity=31.6872427983539, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI169234807, Length=272, Percent_Identity=29.4117647058824, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI62750347, Length=208, Percent_Identity=34.6153846153846, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI62750349, Length=208, Percent_Identity=34.6153846153846, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI226529806, Length=210, Percent_Identity=34.2857142857143, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI8923769, Length=199, Percent_Identity=29.1457286432161, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI262073088, Length=162, Percent_Identity=30.2469135802469, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13128860, Length=201, Percent_Identity=26.3681592039801, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI13128862, Length=287, Percent_Identity=24.0418118466899, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI293336691, Length=179, Percent_Identity=25.6983240223464, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193209491, Length=208, Percent_Identity=36.5384615384615, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17540334, Length=293, Percent_Identity=27.3037542662116, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193206283, Length=293, Percent_Identity=27.3037542662116, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17540332, Length=293, Percent_Identity=27.3037542662116, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI25154020, Length=242, Percent_Identity=35.1239669421488, Blast_Score=104, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25154022, Length=217, Percent_Identity=35.0230414746544, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17537347, Length=241, Percent_Identity=31.5352697095436, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17508561, Length=201, Percent_Identity=27.363184079602, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534739, Length=221, Percent_Identity=28.0542986425339, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17561978, Length=200, Percent_Identity=27.5, Blast_Score=73, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324307, Length=266, Percent_Identity=31.203007518797, Blast_Score=122, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6321244, Length=201, Percent_Identity=25.8706467661692, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323999, Length=201, Percent_Identity=26.865671641791, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24642146, Length=363, Percent_Identity=28.6501377410468, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24642144, Length=363, Percent_Identity=28.6501377410468, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24642142, Length=363, Percent_Identity=28.6501377410468, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281360899, Length=363, Percent_Identity=28.6501377410468, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI281360799, Length=171, Percent_Identity=36.8421052631579, Blast_Score=109, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24641720, Length=171, Percent_Identity=36.8421052631579, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281360801, Length=171, Percent_Identity=36.8421052631579, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644244, Length=293, Percent_Identity=23.2081911262799, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24657891, Length=204, Percent_Identity=27.4509803921569, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 49739; Mature: 49739

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKAKRRLGLVFFPAFDWAISPTHPEREERLLYTQDQVFEEGILDIEGIREYRPRLASTG
CCCCCCCCCEEEEECCCCEECCCCCCHHHCEEECHHHHHHHCCCCHHHHHHHHHHCCCCC
DVERVHICVPDVQSRTTESHLIAAGGAIVAAEAVLKGEVDKAFAIIRPPGHHSFRIVHGA
CCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECC
RGFCNINMEAIMLEYIRRHYGPKRIAIVDTDCHHGDGSQDIYWHDKDTLYISLHQDGRTL
CCEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEECCCCEE
FPGTGFLNEFGGPNAFGYTLNLPLPPDTGEEGFLYALEHFILPVLAEFKPDLVINSAGQD
CCCCCHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
NHYTDPITNMRFSAQGYARLNDRLQPDIAVLEGGYSIEGALPYVNAGIILALAGLDYSRV
CCCCCCCCCCEECCCCHHHHCCCCCCCEEEEECCCEECCCCCEECCCEEEEEECCCHHHC
REPDYTPEKVAQSPRVSEYIARLCDESYQAWQQRDTLREEYIRGKKEISRRRRIFYDTEG
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEECCHH
LMETQQETTRVCHDCGGVTWIDSRTDQGRHILAIFIPRDACPRCQEEGHALFESSQTIDY
HHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCHHHCCCHHHCCCCCCCC
PDGVFLQDRLEDKLFKK
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYKAKRRLGLVFFPAFDWAISPTHPEREERLLYTQDQVFEEGILDIEGIREYRPRLASTG
CCCCCCCCCEEEEECCCCEECCCCCCHHHCEEECHHHHHHHCCCCHHHHHHHHHHCCCCC
DVERVHICVPDVQSRTTESHLIAAGGAIVAAEAVLKGEVDKAFAIIRPPGHHSFRIVHGA
CCCEEEEECCCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECC
RGFCNINMEAIMLEYIRRHYGPKRIAIVDTDCHHGDGSQDIYWHDKDTLYISLHQDGRTL
CCEEECCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCEEEECCCEEEEEEECCCCEE
FPGTGFLNEFGGPNAFGYTLNLPLPPDTGEEGFLYALEHFILPVLAEFKPDLVINSAGQD
CCCCCHHHHCCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCC
NHYTDPITNMRFSAQGYARLNDRLQPDIAVLEGGYSIEGALPYVNAGIILALAGLDYSRV
CCCCCCCCCCEECCCCHHHHCCCCCCCEEEEECCCEECCCCCEECCCEEEEEECCCHHHC
REPDYTPEKVAQSPRVSEYIARLCDESYQAWQQRDTLREEYIRGKKEISRRRRIFYDTEG
CCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCEEECCHH
LMETQQETTRVCHDCGGVTWIDSRTDQGRHILAIFIPRDACPRCQEEGHALFESSQTIDY
HHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEECCCCCCCHHHCCCHHHCCCCCCCC
PDGVFLQDRLEDKLFKK
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]