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The map label for this gene is paaK [H]

Identifier: 83589784

GI number: 83589784

Start: 966547

End: 967833

Strand: Reverse

Name: paaK [H]

Synonym: Moth_0933

Alternate gene names: 83589784

Gene position: 967833-966547 (Counterclockwise)

Preceding gene: 83589785

Following gene: 83589782

Centisome position: 36.82

GC content: 60.76

Gene sequence:

>1287_bases
ATGAGCCTGTCCGAAGCAAAAAACTGCCAACGCAAGTTCGACTACGATTGCCTGTACCGGCAGCAGGAACCGCACTTGCA
GGCCCTGGTGCAGCGCCTCTTTGCCCATTCCCCTTACTACCGGGAAAAGCTGGCGGCGGCCGGCCTTACACCCGGAGACA
TCCGGACGGTAGCCGACCTGGAGCATGTCCCCCTGACGGACAAATGGGAGCTACGCAATGGTAAACCCCTGGCCCTGATG
GCCGTTCCCGAAGAAAAAGTCGTCCGCATCCACTCCTCTTCGGGAACTACGGGTAAACCCATTATCATTCCCTACACGGC
CTACGACGTGGCCGTCTGGGCGCAGATGATGGCCCGCTGCTTCGCCATGGCCGGGGTCACCAACCGTGACCGGGTCCAGG
TTACCCCTGGGTACGGCCTCTGGACGGCGGGCATCGGCTTCCAGGCCGGTATTGAGTACCTGGGGGCCATGGTGATCCCC
ATGGGACCGGGGAATACTGAAAAACAACTGGAGATGATGGTCGATCTCCAGGCTACCGTCCTTGCGGCCACGGCTTCCTA
CGCTCTCTTCCTGGCCGAAGAGATCGACCGCCGGGGCCTTAAGGATCAACTGGCCCTACGGGTAGGGGTCCTGGGCTCCG
AGCGCTGGGGCGAGAAGATGCGGCAGCGAATTGAAGACCTTCTGGGCATCGAAACCTTTGATATTTACGGCTTAACGGAG
ATCTACGGCCCGGGCATCGGCATCGACTGCCCGGCCCATGAGGGTATTCATATGTGGACGGATCACCTGCTCCTGGAGGT
TATCGACCCGGCGACAGGCAAGCAATTACCTCCGGGGGAGACTGGTGAGCTGGTGATAACTACCCTCACCAAAGAGGGTA
TGCCCCTCCTCCGTTACCGCACCCACGACCTGACCTGCCTAAAGAGGGAAGCCTGCTCCTGCGGTTCGCCCTACCCCATG
ATTGAGCGCGTCCTGGGCCGGACCGACGACATGGTCAAGATCAAGGGTGTCAACATCTTCCCGGGCCAGGTAGATCATGT
CCTCCACCTCACCCCCGGCGCCGGGAGCGAGTACCAGCTTATCCTCACCCGGCAGGAAGGTAAAGACCGGCTGCTGGTAA
AAATAGAGTACCTGCCCGGTTATGATGGTGAGTCCACGGCAGCCGAGTGTCGCCGCCAGATCAAGACCCGGATCGGTATC
CTTGCCGACGTGGAAGCCGTGCCCCTGGGAACCCTGCCCCGCAGCGAAAAGAAAACCCGGCGCGTCTACGACTACCGGGA
GACTTAG

Upstream 100 bases:

>100_bases
AAACTCTACTGGCCGCGGCCTTAAAGCTTCTGCCGGACCGGGTCCACGACGTGAACCGACGGGCCTTTCAACTGGGAAAA
CAAGCCCTGGAGGTGTAAAT

Downstream 100 bases:

>100_bases
GTTCACGCTTTACCAAAGGAACAGGCCGGGTAGCGGCACTCGGGGCAGTTCTGGCAGAGGCCCCCGGCCGCCAGCCCGGC
TATATCATGCCGTTCCAACC

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSLSEAKNCQRKFDYDCLYRQQEPHLQALVQRLFAHSPYYREKLAAAGLTPGDIRTVADLEHVPLTDKWELRNGKPLALM
AVPEEKVVRIHSSSGTTGKPIIIPYTAYDVAVWAQMMARCFAMAGVTNRDRVQVTPGYGLWTAGIGFQAGIEYLGAMVIP
MGPGNTEKQLEMMVDLQATVLAATASYALFLAEEIDRRGLKDQLALRVGVLGSERWGEKMRQRIEDLLGIETFDIYGLTE
IYGPGIGIDCPAHEGIHMWTDHLLLEVIDPATGKQLPPGETGELVITTLTKEGMPLLRYRTHDLTCLKREACSCGSPYPM
IERVLGRTDDMVKIKGVNIFPGQVDHVLHLTPGAGSEYQLILTRQEGKDRLLVKIEYLPGYDGESTAAECRRQIKTRIGI
LADVEAVPLGTLPRSEKKTRRVYDYRET

Sequences:

>Translated_428_residues
MSLSEAKNCQRKFDYDCLYRQQEPHLQALVQRLFAHSPYYREKLAAAGLTPGDIRTVADLEHVPLTDKWELRNGKPLALM
AVPEEKVVRIHSSSGTTGKPIIIPYTAYDVAVWAQMMARCFAMAGVTNRDRVQVTPGYGLWTAGIGFQAGIEYLGAMVIP
MGPGNTEKQLEMMVDLQATVLAATASYALFLAEEIDRRGLKDQLALRVGVLGSERWGEKMRQRIEDLLGIETFDIYGLTE
IYGPGIGIDCPAHEGIHMWTDHLLLEVIDPATGKQLPPGETGELVITTLTKEGMPLLRYRTHDLTCLKREACSCGSPYPM
IERVLGRTDDMVKIKGVNIFPGQVDHVLHLTPGAGSEYQLILTRQEGKDRLLVKIEYLPGYDGESTAAECRRQIKTRIGI
LADVEAVPLGTLPRSEKKTRRVYDYRET
>Mature_427_residues
SLSEAKNCQRKFDYDCLYRQQEPHLQALVQRLFAHSPYYREKLAAAGLTPGDIRTVADLEHVPLTDKWELRNGKPLALMA
VPEEKVVRIHSSSGTTGKPIIIPYTAYDVAVWAQMMARCFAMAGVTNRDRVQVTPGYGLWTAGIGFQAGIEYLGAMVIPM
GPGNTEKQLEMMVDLQATVLAATASYALFLAEEIDRRGLKDQLALRVGVLGSERWGEKMRQRIEDLLGIETFDIYGLTEI
YGPGIGIDCPAHEGIHMWTDHLLLEVIDPATGKQLPPGETGELVITTLTKEGMPLLRYRTHDLTCLKREACSCGSPYPMI
ERVLGRTDDMVKIKGVNIFPGQVDHVLHLTPGAGSEYQLILTRQEGKDRLLVKIEYLPGYDGESTAAECRRQIKTRIGIL
ADVEAVPLGTLPRSEKKTRRVYDYRET

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=425, Percent_Identity=42.1176470588235, Blast_Score=320, Evalue=8e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47731; Mature: 47600

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSEAKNCQRKFDYDCLYRQQEPHLQALVQRLFAHSPYYREKLAAAGLTPGDIRTVADL
CCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCC
EHVPLTDKWELRNGKPLALMAVPEEKVVRIHSSSGTTGKPIIIPYTAYDVAVWAQMMARC
CCCCCCCCEECCCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
FAMAGVTNRDRVQVTPGYGLWTAGIGFQAGIEYLGAMVIPMGPGNTEKQLEMMVDLQATV
HHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHH
LAATASYALFLAEEIDRRGLKDQLALRVGVLGSERWGEKMRQRIEDLLGIETFDIYGLTE
HHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCEEEECCHHH
IYGPGIGIDCPAHEGIHMWTDHLLLEVIDPATGKQLPPGETGELVITTLTKEGMPLLRYR
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEE
THDLTCLKREACSCGSPYPMIERVLGRTDDMVKIKGVNIFPGQVDHVLHLTPGAGSEYQL
CCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCEECCCCCCEEEEECCCCCCCEEE
ILTRQEGKDRLLVKIEYLPGYDGESTAAECRRQIKTRIGILADVEAVPLGTLPRSEKKTR
EEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCHHHHH
RVYDYRET
HHCCCCCC
>Mature Secondary Structure 
SLSEAKNCQRKFDYDCLYRQQEPHLQALVQRLFAHSPYYREKLAAAGLTPGDIRTVADL
CCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHCC
EHVPLTDKWELRNGKPLALMAVPEEKVVRIHSSSGTTGKPIIIPYTAYDVAVWAQMMARC
CCCCCCCCEECCCCCEEEEEECCCCCEEEEECCCCCCCCCEEEEECHHHHHHHHHHHHHH
FAMAGVTNRDRVQVTPGYGLWTAGIGFQAGIEYLGAMVIPMGPGNTEKQLEMMVDLQATV
HHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHHCEEEEECCCCCCHHHHHHHHHHHHHH
LAATASYALFLAEEIDRRGLKDQLALRVGVLGSERWGEKMRQRIEDLLGIETFDIYGLTE
HHHHHHHHHHHHHHHHHCCCHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCEEEECCHHH
IYGPGIGIDCPAHEGIHMWTDHLLLEVIDPATGKQLPPGETGELVITTLTKEGMPLLRYR
HCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEE
THDLTCLKREACSCGSPYPMIERVLGRTDDMVKIKGVNIFPGQVDHVLHLTPGAGSEYQL
CCCHHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCEECCCCCCEEEEECCCCCCCEEE
ILTRQEGKDRLLVKIEYLPGYDGESTAAECRRQIKTRIGILADVEAVPLGTLPRSEKKTR
EEEECCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCHHHHH
RVYDYRET
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]