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The map label for this gene is hhoB [H]

Identifier: 83589364

GI number: 83589364

Start: 517103

End: 518146

Strand: Reverse

Name: hhoB [H]

Synonym: Moth_0500

Alternate gene names: 83589364

Gene position: 518146-517103 (Counterclockwise)

Preceding gene: 83589365

Following gene: 83589362

Centisome position: 19.71

GC content: 50.1

Gene sequence:

>1044_bases
ATGAAATCAATCAATGTGAACACTGTGCTGGCCGTTATGCTGAGCGGTTTGTTAATCATGGCCGGGGGTTTTGGTCTGGC
CAGGATTTACGATAACATGCATAATCAAGTGGTTGCAGAGGCATCTAAACTCGGTCCTATCGAGGAGAACCACTCTGAGT
CGGCCAAGTCCCAGGATTTAAAAAGCATTATTGCCGAGAATCAAAAGCTAGTAGTGTGTCTAGAGGTTGAGCTTGATTAC
GGTAAGGTACAGGGTTCCGGATTTCTTTATAACCGGCAGGGGGATGTAATAACCAATGCCCACGTGGTGGGTGACGCCAG
AACTTGCCGGGTCAAATTGTCCGATGGCACAGTTTATCAAGGCACAGTTATCGGGCGTGGGGAACAAATTGATGTGGCTC
TGGTCAGGGTGCCGGAACTGGCTGGTAAGGAACCAATGAAAATTGCCCGGGATAGAATGGCAGAAGTGGGAGATGAAGTG
ATCGCCCTGGGCAGTCCCCTTGGATTACAAAATACCGCCACCACAGGAATCATCAGCGGTGTCAACCGGGATTTAGATAT
CGGGGATTATCATTATAAGGGGCTATACCAAATTTCTGCCCCCATCTCGCATGGCAGTAGCGGAGGACCGTTACTGGATC
GACATACCGGCGAGGTGCTGGGTGTTAATTCCGCCGGGGCCGAGGGAGAAAATATCGGCTTTAGCATACCCATCACCCAG
GTTTTACCCCTGGTGGAAAACTGGTCAAAAAACCCCAGTACAGCACCGGTGCAGCCAACCACCGGTACTGTCGGGAAAAT
TTCCGAGAAAGAATTAGCCACTGCTGCATCCTACCTGGTTGAGGACTTTTACACTTGTGTCAATAACGGGGATTATGTAG
GGGCCTATGCTCTGCTGGGAAGTGACTGGCAGGCCAAACAGCCCTATGAGAAGTTCCGGGCCGGCTATTTAAATACACTT
TCAGTCTCAGACGCATTTTTAAAACCAGGCCGCCATTCGGCAACTCCTCAATTACTTGACTGGAATGCCAGTGTCGCTCC
TTGA

Upstream 100 bases:

>100_bases
GGATCAGGGTAGCTTTGACAACACTTCTTACGGGTTGTGGCAGGGTAATCGAGTAAAAATTAACAGGATCACCTGGTATT
TAAGGTAGTGGGAGAGGCTT

Downstream 100 bases:

>100_bases
TCCAGCGGGCCTCAACGGCATCAAAACGAATAACCACTTCATGGACAAGAATTGAGGATTTACGAGTTGTGGCGGTTAAC
CAGGACAGTGCAGAGATTAG

Product: peptidase S1 and S6, chymotrypsin/Hap

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MKSINVNTVLAVMLSGLLIMAGGFGLARIYDNMHNQVVAEASKLGPIEENHSESAKSQDLKSIIAENQKLVVCLEVELDY
GKVQGSGFLYNRQGDVITNAHVVGDARTCRVKLSDGTVYQGTVIGRGEQIDVALVRVPELAGKEPMKIARDRMAEVGDEV
IALGSPLGLQNTATTGIISGVNRDLDIGDYHYKGLYQISAPISHGSSGGPLLDRHTGEVLGVNSAGAEGENIGFSIPITQ
VLPLVENWSKNPSTAPVQPTTGTVGKISEKELATAASYLVEDFYTCVNNGDYVGAYALLGSDWQAKQPYEKFRAGYLNTL
SVSDAFLKPGRHSATPQLLDWNASVAP

Sequences:

>Translated_347_residues
MKSINVNTVLAVMLSGLLIMAGGFGLARIYDNMHNQVVAEASKLGPIEENHSESAKSQDLKSIIAENQKLVVCLEVELDY
GKVQGSGFLYNRQGDVITNAHVVGDARTCRVKLSDGTVYQGTVIGRGEQIDVALVRVPELAGKEPMKIARDRMAEVGDEV
IALGSPLGLQNTATTGIISGVNRDLDIGDYHYKGLYQISAPISHGSSGGPLLDRHTGEVLGVNSAGAEGENIGFSIPITQ
VLPLVENWSKNPSTAPVQPTTGTVGKISEKELATAASYLVEDFYTCVNNGDYVGAYALLGSDWQAKQPYEKFRAGYLNTL
SVSDAFLKPGRHSATPQLLDWNASVAP
>Mature_347_residues
MKSINVNTVLAVMLSGLLIMAGGFGLARIYDNMHNQVVAEASKLGPIEENHSESAKSQDLKSIIAENQKLVVCLEVELDY
GKVQGSGFLYNRQGDVITNAHVVGDARTCRVKLSDGTVYQGTVIGRGEQIDVALVRVPELAGKEPMKIARDRMAEVGDEV
IALGSPLGLQNTATTGIISGVNRDLDIGDYHYKGLYQISAPISHGSSGGPLLDRHTGEVLGVNSAGAEGENIGFSIPITQ
VLPLVENWSKNPSTAPVQPTTGTVGKISEKELATAASYLVEDFYTCVNNGDYVGAYALLGSDWQAKQPYEKFRAGYLNTL
SVSDAFLKPGRHSATPQLLDWNASVAP

Specific function: A putative protease, its function overlaps that of the related putative proteases HtrA and HhoA [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=163, Percent_Identity=36.8098159509202, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI24308541, Length=160, Percent_Identity=38.125, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI22129776, Length=186, Percent_Identity=32.7956989247312, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7019477, Length=158, Percent_Identity=41.1392405063291, Blast_Score=76, Evalue=4e-14,
Organism=Escherichia coli, GI1786356, Length=162, Percent_Identity=35.8024691358025, Blast_Score=95, Evalue=8e-21,
Organism=Escherichia coli, GI1789630, Length=163, Percent_Identity=34.3558282208589, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789629, Length=161, Percent_Identity=36.6459627329193, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646839, Length=169, Percent_Identity=36.6863905325444, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 37018; Mature: 37018

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSINVNTVLAVMLSGLLIMAGGFGLARIYDNMHNQVVAEASKLGPIEENHSESAKSQDL
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KSIIAENQKLVVCLEVELDYGKVQGSGFLYNRQGDVITNAHVVGDARTCRVKLSDGTVYQ
HHHHHCCCEEEEEEEEEECCCEEECCEEEEECCCCEEEEEEEECCCEEEEEEECCCEEEE
GTVIGRGEQIDVALVRVPELAGKEPMKIARDRMAEVGDEVIALGSPLGLQNTATTGIISG
EEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHC
VNRDLDIGDYHYKGLYQISAPISHGSSGGPLLDRHTGEVLGVNSAGAEGENIGFSIPITQ
CCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCHHH
VLPLVENWSKNPSTAPVQPTTGTVGKISEKELATAASYLVEDFYTCVNNGDYVGAYALLG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
SDWQAKQPYEKFRAGYLNTLSVSDAFLKPGRHSATPQLLDWNASVAP
CCCCCCCCHHHHHCCCCEEEECCHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MKSINVNTVLAVMLSGLLIMAGGFGLARIYDNMHNQVVAEASKLGPIEENHSESAKSQDL
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
KSIIAENQKLVVCLEVELDYGKVQGSGFLYNRQGDVITNAHVVGDARTCRVKLSDGTVYQ
HHHHHCCCEEEEEEEEEECCCEEECCEEEEECCCCEEEEEEEECCCEEEEEEECCCEEEE
GTVIGRGEQIDVALVRVPELAGKEPMKIARDRMAEVGDEVIALGSPLGLQNTATTGIISG
EEEECCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHC
VNRDLDIGDYHYKGLYQISAPISHGSSGGPLLDRHTGEVLGVNSAGAEGENIGFSIPITQ
CCCCCCCCCEECCEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCHHH
VLPLVENWSKNPSTAPVQPTTGTVGKISEKELATAASYLVEDFYTCVNNGDYVGAYALLG
HHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEC
SDWQAKQPYEKFRAGYLNTLSVSDAFLKPGRHSATPQLLDWNASVAP
CCCCCCCCHHHHHCCCCEEEECCHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]