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The map label for this gene is ade

Identifier: 83589328

GI number: 83589328

Start: 465936

End: 467726

Strand: Reverse

Name: ade

Synonym: Moth_0463

Alternate gene names: 83589328

Gene position: 467726-465936 (Counterclockwise)

Preceding gene: 83589333

Following gene: 83589327

Centisome position: 17.79

GC content: 63.09

Gene sequence:

>1791_bases
GTGCTCCCAACCAGGCGTCCCCTGGCTGAAGTCACCAGAGAACTGGTGGCTGTGGCTACCGGAAAACTCCCTGCCGACAC
CGTTATCAAGGGCGGCAAAGTAGTAAACGTTTTTACCGGCGAAATACTGCCCTGGGATATCGCCATCAAAAATGGCCGCA
TTGCCAGCGTCGGTGACGTATCCGCGGCTGTGGGGCCGGAAACGGAGGTGATTGACGCCAGCGGCTATTACCTTTGCCCG
GGTTTCATGGATGGCCATGTCCATGTGGAAAGCAGTATGGTGACGGTGACCCAGTTCGCCCGGGCCGTCCTCCCCGGCGG
CACCACGGCGATTTTTATGGACCCCCATGAGATTGCCAATGTCCTGGGGATGGACGGGGTAAAGCTGATGGTGGACGAGG
GCCGGGAACTCCCCTTAAAGGTCTTTGCCACCATGCCTTCCTGTGTTCCGGCTGCGCCCGGATTTGAGGACGCCGGTGCC
AGCTTTGGGCCGGAAGAGGTGGCCGCCGCCATGCAGTGGCCCGGTATCTGCGGCCTGGGGGAAATGATGAACTTCCCCGG
TGTCCTGGCCGGTGATCCGGCCGTCCACGGCGAACTAAGGGCCACCCTGGCGGCCGGTAAACCCATCACCGGACACTTCG
CCATGCCCGCCGACTTTCAGGGCCTGGCCGGCTATACGGCCGCCGGCATCTCTTCCTGCCACGAATCCACCCGTACCGAA
GACGCCCTCAACCGCCTGCGCCTCGGCATGTATGCCATGATGCGGGAGGGATCGGCCTGGCACGATATCAAGGCCACCAT
TAAGAGTCTGACAGAAACCCGGGTCGACAGCCGCCGGGCCATGCTGGTGAGCGACGACACCCACCCGGAAACCCTGTTAT
CCACCGGGCACTTAAACCATGTGGTCCGCCGGGCCATCGAAGAGGGCCTGAACCCCATCCGGGCCATCCAGGCGGTAACC
ATTAATACGGCCGAGTGCTTTGGCGTAGCCCAGGACCTGGGGGCCATTGCGCCGGGGCGTTATGCCGATATCCTCTTCTT
GAAGGACCTGGCCCGGGTAGCGATAGATAAGGTTATGGTCGACGGCCGGGTGGTTGCCGCCGGGGGCAGGCTCCTGGTGG
ACCTGCCGGCAGTCGCCTACCCCGATAGGGTGCGCCATTCGGTACACTTAAAGGAACCTCTGACCCCCTGGCATTTCCGG
ATCAACGCCCCGGCCGGCAAAAGCCGGGTTCAGGTCCGGGTAATGGAAATTATTGAAGCCAATGTCAACACCCGCCACCT
GACAGTCACCGTACCGGTGGTGGACGGCCAGGTCACAGCCGGGGTCGAGGCCGACCTGGCCAAAGTGGCGGTTGTCGAGC
GCCACGGCGGCAACGGCAGTATCGGCCTGGGCTTTGTCCGGGGTTTCGGCTTTAAAGCCGGCGCCGTGGCCTCTACGGTG
GCCCACGACAGCCACAACCTCCTCATTGTTGGTATGAATGACGCCGATATGGCCCTGGCGGGCAACACCCTGGCTGGATG
CGGCGGTGGTATGGTGGCCGTCAGGGACGGCCAGGTTCTGGCCCTCCTGCCCCTGCCCATTGCCGGCCTGATGTCGGACA
GGCCGGTGGAAGAGGTGGCCGCCCGGTTGGCAGCCGTCCACCGGGCCTGGCAGGAACTGGGGTGCCGGCTGGTGTCGCCC
TTTATGACCATGGCCCTCCTTTCCCTGCCGGTCCTGCCGGAGTTACGCCTGACCAACCGCGGCCTGGTAGACACCCTGCA
GTTTAAAATGGTTGACTTGATAACCGGTTGA

Upstream 100 bases:

>100_bases
TAAAAATAAACCTGCAGTAAAGTATTGTTAAATAAATCTTGTCATTTTTTTGATGTAGCTCTATACTGAAATTAACTCTA
TGATAAGGAGATGGCTGTCA

Downstream 100 bases:

>100_bases
ATCTCCTCACCCCGGCCCCTGGCCGGGGCTTTTCTTTAGCTGCCCGGGGCTCCGGATTATCCGGAACTCCCTTGCTTCCT
ACCCCTTTAAAGGTGTAGGA

Product: adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MLPTRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILPWDIAIKNGRIASVGDVSAAVGPETEVIDASGYYLCP
GFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIANVLGMDGVKLMVDEGRELPLKVFATMPSCVPAAPGFEDAGA
SFGPEEVAAAMQWPGICGLGEMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRTE
DALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLNHVVRRAIEEGLNPIRAIQAVT
INTAECFGVAQDLGAIAPGRYADILFLKDLARVAIDKVMVDGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFR
INAPAGKSRVQVRVMEIIEANVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGFKAGAVASTV
AHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVEEVAARLAAVHRAWQELGCRLVSP
FMTMALLSLPVLPELRLTNRGLVDTLQFKMVDLITG

Sequences:

>Translated_596_residues
MLPTRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILPWDIAIKNGRIASVGDVSAAVGPETEVIDASGYYLCP
GFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIANVLGMDGVKLMVDEGRELPLKVFATMPSCVPAAPGFEDAGA
SFGPEEVAAAMQWPGICGLGEMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRTE
DALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLNHVVRRAIEEGLNPIRAIQAVT
INTAECFGVAQDLGAIAPGRYADILFLKDLARVAIDKVMVDGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFR
INAPAGKSRVQVRVMEIIEANVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGFKAGAVASTV
AHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVEEVAARLAAVHRAWQELGCRLVSP
FMTMALLSLPVLPELRLTNRGLVDTLQFKMVDLITG
>Mature_596_residues
MLPTRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILPWDIAIKNGRIASVGDVSAAVGPETEVIDASGYYLCP
GFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIANVLGMDGVKLMVDEGRELPLKVFATMPSCVPAAPGFEDAGA
SFGPEEVAAAMQWPGICGLGEMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRTE
DALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLNHVVRRAIEEGLNPIRAIQAVT
INTAECFGVAQDLGAIAPGRYADILFLKDLARVAIDKVMVDGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFR
INAPAGKSRVQVRVMEIIEANVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGFKAGAVASTV
AHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVEEVAARLAAVHRAWQELGCRLVSP
FMTMALLSLPVLPELRLTNRGLVDTLQFKMVDLITG

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family

Homologues:

Organism=Escherichia coli, GI1790098, Length=587, Percent_Identity=35.6047700170358, Blast_Score=323, Evalue=3e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ADEC_MOOTA (Q2RL95)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_429337.1
- ProteinModelPortal:   Q2RL95
- STRING:   Q2RL95
- GeneID:   3830892
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_0463
- NMPDR:   fig|264732.9.peg.442
- eggNOG:   COG1001
- HOGENOM:   HBG725357
- OMA:   VGLGEMM
- PhylomeDB:   Q2RL95
- ProtClustDB:   CLSK2773060
- BioCyc:   MTHE264732:MOTH_0463-MONOMER
- HAMAP:   MF_01518
- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01178

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.4.2

Molecular weight: Translated: 63031; Mature: 63031

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILPWDIAIKNGRIASVGDV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCEEEEEEEEECCEEEECCCC
SAAVGPETEVIDASGYYLCPGFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIAN
HHCCCCCCEEEECCCCEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECHHHHHH
VLGMDGVKLMVDEGRELPLKVFATMPSCVPAAPGFEDAGASFGPEEVAAAMQWPGICGLG
HHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCH
EMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRTE
HHHCCCCEECCCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHH
DALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLNH
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHH
VVRRAIEEGLNPIRAIQAVTINTAECFGVAQDLGAIAPGRYADILFLKDLARVAIDKVMV
HHHHHHHHCCCHHHHEEEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
DGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFRINAPAGKSRVQVRVMEIIEA
CCEEEEECCEEEEECCCCCCCHHHHCEEEECCCCCCEEEEEECCCCCCHHHEEEEHHHHC
NVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGFKAGAVASTV
CCCCEEEEEEEEEECCCEECCCHHHHHEEEEEEECCCCCCEEEHHHHCCCCCCCHHHHHH
AHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVEEVA
EECCCCEEEEECCCCCEEEECCCEECCCCCEEEEECCCEEEEECCCHHHHCCCCCHHHHH
ARLAAVHRAWQELGCRLVSPFMTMALLSLPVLPELRLTNRGLVDTLQFKMVDLITG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPTRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILPWDIAIKNGRIASVGDV
CCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCEEEEEEECCEEEEEEEEECCEEEECCCC
SAAVGPETEVIDASGYYLCPGFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIAN
HHCCCCCCEEEECCCCEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECHHHHHH
VLGMDGVKLMVDEGRELPLKVFATMPSCVPAAPGFEDAGASFGPEEVAAAMQWPGICGLG
HHCCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCH
EMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRTE
HHHCCCCEECCCCCCCCHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHH
DALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLNH
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCHHHH
VVRRAIEEGLNPIRAIQAVTINTAECFGVAQDLGAIAPGRYADILFLKDLARVAIDKVMV
HHHHHHHHCCCHHHHEEEEEEECHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHC
DGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFRINAPAGKSRVQVRVMEIIEA
CCEEEEECCEEEEECCCCCCCHHHHCEEEECCCCCCEEEEEECCCCCCHHHEEEEHHHHC
NVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGFKAGAVASTV
CCCCEEEEEEEEEECCCEECCCHHHHHEEEEEEECCCCCCEEEHHHHCCCCCCCHHHHHH
AHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVEEVA
EECCCCEEEEECCCCCEEEECCCEECCCCCEEEEECCCEEEEECCCHHHHCCCCCHHHHH
ARLAAVHRAWQELGCRLVSPFMTMALLSLPVLPELRLTNRGLVDTLQFKMVDLITG
HHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA