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The map label for this gene is hepT [H]

Identifier: 83589030

GI number: 83589030

Start: 158942

End: 159904

Strand: Reverse

Name: hepT [H]

Synonym: Moth_0158

Alternate gene names: 83589030

Gene position: 159904-158942 (Counterclockwise)

Preceding gene: 83589051

Following gene: 83589010

Centisome position: 6.08

GC content: 67.6

Gene sequence:

>963_bases
TTGAACCTGGCGGAAACCCGGCGGGTCCTGGCCGAAGCCGTAGCCGCCACGGACCCCAGGCTGCAGGAACTTTTGGACTA
CGCCCTGGAAGGCGGTAAAGGCCTGCGACCCACCCTGGTTTTTTTATGCGCCCGTTTCGGTATCTATGACGCCCTGGAGG
CCGGGCGGGTGGCGGCGGCCATCGAGCTGGTTCACCTGGCTTCCCTGGTCCACGACGATATCCTCGACGGGGCGGCGGTG
CGGCGCAACCGCCCCGCCCTCTACCGCGCCTACGGGACGGTGCCCGCCGTCCTCACCGGCGATTACCTCTTTGCCACCGC
CTTCGGCCTCCTGGCCAAGGGCAAGAAGGCCGTCCTCTATACGGTGACGGAGGCCATTCGCTCCATGTGCAGCGGCGAGA
TCGGGCAGCTGAAGGGCGGGCTTGCCGGCCCGGAGGCCTACTTTACCTATATTGGCCAGAAGACGGCCGCCCTGATAAGC
GCCGCCTGCCGCTGCGGCGCCATCCTGGGCCGGGTGAAACGAAACCAACAGGAATGCCTGGCGCAGTTCGGCTGGCACCT
GGGCCTGGCCTACCAGATTGTCGACGACTGCCTGGATCTCTTCGGGTCCCCGGAAAGGATGGGCAAGCCCTGCCGCCAGG
ACCTGGCCCGGGGCCTCCTGACCCTGCCGGTTTTACGTTTCCTCGCGGTCACGCCGGATGCCGCCTGCTGGCGGGAAAGG
CTGGCCCGCGGCCTCGAGGCGGCAGAAATGGAGGAACTGGTTGAAGCCGCCCGGGGTCTCGGCTGTGATACCTACACCGC
TGCCGTGGCGGCTGATGAGGTTACCCGGGCCCTGACGGCCCTGGACCGGTTGCCGGTAAACCCGGTCCAGGATGAGCTGG
CCCTCCTGGCCGCCCGGACCCTGGCCCCCCTGGAGGACCCGGATTGTCCGGCCGCATACCCCGGTATGACTGCTGCCGGT
TAA

Upstream 100 bases:

>100_bases
ACGGCTTTTAGCAAATACTAGCATTGCCGGGAAGTCCGGTACCGGCACTCGTGGTGAGCGTGCCAGCGGGGACAACTTTT
TATGACAGGAGTGAACTACT

Downstream 100 bases:

>100_bases
ACTACGCCCGCCCGGCGCAAGACCCGGCAGAGGCGGTAGAGGTTGCGGGAGAAGGGGCCGGCGGTCCGGAGGATTGCCTG
CCGGGCCGGGAGCTGCTCCT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: HEPPP synthase subunit 2 [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MNLAETRRVLAEAVAATDPRLQELLDYALEGGKGLRPTLVFLCARFGIYDALEAGRVAAAIELVHLASLVHDDILDGAAV
RRNRPALYRAYGTVPAVLTGDYLFATAFGLLAKGKKAVLYTVTEAIRSMCSGEIGQLKGGLAGPEAYFTYIGQKTAALIS
AACRCGAILGRVKRNQQECLAQFGWHLGLAYQIVDDCLDLFGSPERMGKPCRQDLARGLLTLPVLRFLAVTPDAACWRER
LARGLEAAEMEELVEAARGLGCDTYTAAVAADEVTRALTALDRLPVNPVQDELALLAARTLAPLEDPDCPAAYPGMTAAG

Sequences:

>Translated_320_residues
MNLAETRRVLAEAVAATDPRLQELLDYALEGGKGLRPTLVFLCARFGIYDALEAGRVAAAIELVHLASLVHDDILDGAAV
RRNRPALYRAYGTVPAVLTGDYLFATAFGLLAKGKKAVLYTVTEAIRSMCSGEIGQLKGGLAGPEAYFTYIGQKTAALIS
AACRCGAILGRVKRNQQECLAQFGWHLGLAYQIVDDCLDLFGSPERMGKPCRQDLARGLLTLPVLRFLAVTPDAACWRER
LARGLEAAEMEELVEAARGLGCDTYTAAVAADEVTRALTALDRLPVNPVQDELALLAARTLAPLEDPDCPAAYPGMTAAG
>Mature_320_residues
MNLAETRRVLAEAVAATDPRLQELLDYALEGGKGLRPTLVFLCARFGIYDALEAGRVAAAIELVHLASLVHDDILDGAAV
RRNRPALYRAYGTVPAVLTGDYLFATAFGLLAKGKKAVLYTVTEAIRSMCSGEIGQLKGGLAGPEAYFTYIGQKTAALIS
AACRCGAILGRVKRNQQECLAQFGWHLGLAYQIVDDCLDLFGSPERMGKPCRQDLARGLLTLPVLRFLAVTPDAACWRER
LARGLEAAEMEELVEAARGLGCDTYTAAVAADEVTRALTALDRLPVNPVQDELALLAARTLAPLEDPDCPAAYPGMTAAG

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=290, Percent_Identity=31.7241379310345, Blast_Score=124, Evalue=1e-28,
Organism=Escherichia coli, GI1789578, Length=316, Percent_Identity=31.6455696202532, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI1786623, Length=222, Percent_Identity=33.7837837837838, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17505681, Length=233, Percent_Identity=32.1888412017167, Blast_Score=107, Evalue=6e-24,
Organism=Saccharomyces cerevisiae, GI6319475, Length=304, Percent_Identity=29.2763157894737, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24651612, Length=285, Percent_Identity=31.2280701754386, Blast_Score=124, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 34194; Mature: 34194

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAETRRVLAEAVAATDPRLQELLDYALEGGKGLRPTLVFLCARFGIYDALEAGRVAAA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IELVHLASLVHDDILDGAAVRRNRPALYRAYGTVPAVLTGDYLFATAFGLLAKGKKAVLY
HHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
TVTEAIRSMCSGEIGQLKGGLAGPEAYFTYIGQKTAALISAACRCGAILGRVKRNQQECL
HHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQFGWHLGLAYQIVDDCLDLFGSPERMGKPCRQDLARGLLTLPVLRFLAVTPDAACWRER
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LARGLEAAEMEELVEAARGLGCDTYTAAVAADEVTRALTALDRLPVNPVQDELALLAART
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAPLEDPDCPAAYPGMTAAG
HCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLAETRRVLAEAVAATDPRLQELLDYALEGGKGLRPTLVFLCARFGIYDALEAGRVAAA
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IELVHLASLVHDDILDGAAVRRNRPALYRAYGTVPAVLTGDYLFATAFGLLAKGKKAVLY
HHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHH
TVTEAIRSMCSGEIGQLKGGLAGPEAYFTYIGQKTAALISAACRCGAILGRVKRNQQECL
HHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQFGWHLGLAYQIVDDCLDLFGSPERMGKPCRQDLARGLLTLPVLRFLAVTPDAACWRER
HHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LARGLEAAEMEELVEAARGLGCDTYTAAVAADEVTRALTALDRLPVNPVQDELALLAART
HHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LAPLEDPDCPAAYPGMTAAG
HCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7629164 [H]