Click here to switch to the map view.

The map label for this gene is tlyC [H]

Identifier: 83595102

GI number: 83595102

Start: 4321247

End: 4322203

Strand: Direct

Name: tlyC [H]

Synonym: Rru_A3773

Alternate gene names: 83595102

Gene position: 4321247-4322203 (Clockwise)

Preceding gene: 83595101

Following gene: 83595103

Centisome position: 99.27

GC content: 66.46

Gene sequence:

>957_bases
ATGAACGGTCATTCCGCCTCCGGCGACAGCCCCTCCCGTAGTCGCGATGGCGACTCGGGCGATAAATCGGACTCCGCCAG
TCGCGGCGGTCTGGCGAGTTTCCTGCGCGGGGTGTTCCGCCCGCGCAACGGCGATGGCGGATTGCGCGATTCTCTTGATG
AACTGATCGAGGACCGCGAGGACTCCGACCTGTCGATGACCGATCAGGAACGCGCGTTGCTGACCAATATCCTGCGGCTG
CGCGATATGACCGTCGAAGACATCATGGTGCCGCGCGCCGATGTGGTCGCCGTCGAGGTTTCCACCCCGGTCGATGTGGC
GATCGAGCGCATCGCCGCTTGCGGTCATTCCCGGCTGCCGGTCTATCGCGACACCCTCGACAACACCCTGGGCATGGTTC
ACGTCAAGGATTTCCTCCGCCGCAAGTCGGGTGACGCCGGCTCGCTCGAGCGGGTGCTGCGCGAGATCCTGTTCGCCGCG
CCCTCGGCCCGGGTCCTCGACCTGCTGCTCGAAATGCGGCTCAAGCGCATTCACATGGCCTTGATCGTCGATGAATACGG
CGGCATCGACGGCTTGGTGACGATCGAGGATCTGGTCGAACAGATCGTCGGCGAGATCGAAGACGAATACGACAGCGTGA
CCGAGCCCGAGCTGACCGTGCACGAGGATGGCACGGTGGTGGTCGACGCCCGGCTCGACCTCGAGGATTTCGAGGAGCGC
TGCGGCCGGTTGTTCACCGACGAGGAACGCGAGGAGATCGATACCCTGGGCGGGCTGGTCTTCCGGCTGGCCGGTCGGGT
GCCGGCGCGCGGCGAATTGGTGCTGCGCGAGGGCGGACCCGAGTTCGAGGTGATCGATGCCGATCCCCGGCGGATCCGCC
GGCTGCGCATTCGCGGCCTCAATCCGCTGCCCTCCCCCGACGCTCCGGCCGGCGGCCCCTCCGGGACCCCGGTTTAA

Upstream 100 bases:

>100_bases
CCCTGGATATGGAAGGCCTGGAGACGGCCATCCTCGGCGCGCGGGGGATCGCCGATCCCTATGCCGATGCCCGTGGACCC
GAGCAGGAAGGATCCGACCG

Downstream 100 bases:

>100_bases
CGTGCGCGCCCGGCTTGCGCGCTGGCGCGCCCAGGTGCGCGGGCTGAGCGGCTGGCGCGGTCGCGGCGCGGCCGTGCTGC
TTGGCCTGCTGGCCAGCGCC

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNGHSASGDSPSRSRDGDSGDKSDSASRGGLASFLRGVFRPRNGDGGLRDSLDELIEDREDSDLSMTDQERALLTNILRL
RDMTVEDIMVPRADVVAVEVSTPVDVAIERIAACGHSRLPVYRDTLDNTLGMVHVKDFLRRKSGDAGSLERVLREILFAA
PSARVLDLLLEMRLKRIHMALIVDEYGGIDGLVTIEDLVEQIVGEIEDEYDSVTEPELTVHEDGTVVVDARLDLEDFEER
CGRLFTDEEREEIDTLGGLVFRLAGRVPARGELVLREGGPEFEVIDADPRRIRRLRIRGLNPLPSPDAPAGGPSGTPV

Sequences:

>Translated_318_residues
MNGHSASGDSPSRSRDGDSGDKSDSASRGGLASFLRGVFRPRNGDGGLRDSLDELIEDREDSDLSMTDQERALLTNILRL
RDMTVEDIMVPRADVVAVEVSTPVDVAIERIAACGHSRLPVYRDTLDNTLGMVHVKDFLRRKSGDAGSLERVLREILFAA
PSARVLDLLLEMRLKRIHMALIVDEYGGIDGLVTIEDLVEQIVGEIEDEYDSVTEPELTVHEDGTVVVDARLDLEDFEER
CGRLFTDEEREEIDTLGGLVFRLAGRVPARGELVLREGGPEFEVIDADPRRIRRLRIRGLNPLPSPDAPAGGPSGTPV
>Mature_318_residues
MNGHSASGDSPSRSRDGDSGDKSDSASRGGLASFLRGVFRPRNGDGGLRDSLDELIEDREDSDLSMTDQERALLTNILRL
RDMTVEDIMVPRADVVAVEVSTPVDVAIERIAACGHSRLPVYRDTLDNTLGMVHVKDFLRRKSGDAGSLERVLREILFAA
PSARVLDLLLEMRLKRIHMALIVDEYGGIDGLVTIEDLVEQIVGEIEDEYDSVTEPELTVHEDGTVVVDARLDLEDFEER
CGRLFTDEEREEIDTLGGLVFRLAGRVPARGELVLREGGPEFEVIDADPRRIRRLRIRGLNPLPSPDAPAGGPSGTPV

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=197, Percent_Identity=31.9796954314721, Blast_Score=101, Evalue=9e-22,
Organism=Escherichia coli, GI1786879, Length=295, Percent_Identity=37.2881355932203, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI145693175, Length=247, Percent_Identity=27.1255060728745, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87082033, Length=232, Percent_Identity=28.8793103448276, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=26.7489711934156, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790664, Length=247, Percent_Identity=22.2672064777328, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34963; Mature: 34963

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGHSASGDSPSRSRDGDSGDKSDSASRGGLASFLRGVFRPRNGDGGLRDSLDELIEDRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
DSDLSMTDQERALLTNILRLRDMTVEDIMVPRADVVAVEVSTPVDVAIERIAACGHSRLP
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
VYRDTLDNTLGMVHVKDFLRRKSGDAGSLERVLREILFAAPSARVLDLLLEMRLKRIHMA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LIVDEYGGIDGLVTIEDLVEQIVGEIEDEYDSVTEPELTVHEDGTVVVDARLDLEDFEER
HEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCHHHHHHH
CGRLFTDEEREEIDTLGGLVFRLAGRVPARGELVLREGGPEFEVIDADPRRIRRLRIRGL
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCC
NPLPSPDAPAGGPSGTPV
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNGHSASGDSPSRSRDGDSGDKSDSASRGGLASFLRGVFRPRNGDGGLRDSLDELIEDRE
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCC
DSDLSMTDQERALLTNILRLRDMTVEDIMVPRADVVAVEVSTPVDVAIERIAACGHSRLP
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCCCC
VYRDTLDNTLGMVHVKDFLRRKSGDAGSLERVLREILFAAPSARVLDLLLEMRLKRIHMA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LIVDEYGGIDGLVTIEDLVEQIVGEIEDEYDSVTEPELTVHEDGTVVVDARLDLEDFEER
HEECCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEECCCHHHHHHH
CGRLFTDEEREEIDTLGGLVFRLAGRVPARGELVLREGGPEFEVIDADPRRIRRLRIRGL
HCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEECCCHHHHHHHHHCCC
NPLPSPDAPAGGPSGTPV
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA