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The map label for this gene is wecG [H]

Identifier: 83595046

GI number: 83595046

Start: 4267371

End: 4268156

Strand: Direct

Name: wecG [H]

Synonym: Rru_A3717

Alternate gene names: 83595046

Gene position: 4267371-4268156 (Clockwise)

Preceding gene: 83595045

Following gene: 83595047

Centisome position: 98.04

GC content: 68.58

Gene sequence:

>786_bases
ATGACGACGGCGGACACCAGGACCGGGGATCTGCCGCCGGGCGTGTCTTATCTGGGCATCGCCTATTCGGGGCTGACCCT
GGAGCAGGCGGCGGCGGCGCTGGCCGCCCGCCCGGCCGGGGCCGCCTTCGCCTATGTGGTGACGCCCAACGCCCAGCATG
TCGTCCATCTCAACCGCGGCGAGCCGTTTTTCACCCTGGCCTATCGCGACGCCTGGCTGCGGCTGTCCGACAGCCGGGTG
CTGGCGGCGTTGACCAAGCTGATTGGCGGCCCCCGCCTGCCGGTGGCCACCGGCAGCGATTTGACGGCCCTGTTGTTTCA
GAGCGTCATCACCGCCGATGACCCTTTGGTGGTGATCGGCGGAACCGCCGAGACCGATGAGCGCCTGCGCGCCATGTTCG
GCCTGCGCCATCTGGTCAGCCACCGCCCGCCGATGGGCGTCTTGCGCAATCCCCAGGCCATCGCCGCCTGCGTGGAGTTC
ATCGCCGCCCATCCCGCCCGCTTCGTCTTCTTCGCCGTCGGCTCGCCCCAGTCCGAGGTGATCGCCCAGCATGCCTTCGC
CAGTGGCCGGGCGACCGGCAGTGGGTTGTGCATCGGCGGGGCCTTGTTGTTCCTGACCGGTCAGGTCAAGCGCGCGCCCT
TGTGGATGCGTCGGCTGGCCCTGGAATGGCTCTATCGGCTGTTGGCCAATCCGCGCGGCCATTTCCGCCGGGTTTTCGTC
GACTCGCTGCCGCTGGTCGGCTTGGTTCTGGCCGATCGCTTCAAAACAAGGCGGTCGGCCAAGTGA

Upstream 100 bases:

>100_bases
TTTTCGTGCCGCGCAGTTCGATCGCCGAGCTTGACCTGTGGGTCGATCAGTATCTCAACCGGGCGATCCCGTTCAGTCGG
GCCCTGACCTATACCTTGCC

Downstream 100 bases:

>100_bases
GCGGCGGGCGCGGGCGGGTTCTGGCCCTCAAGGCGGGCGGCGGACGCATTCGCCCGCTTGCCGGCACTGACGCGCCACCC
CTTCCCCGGCCGATGGTCGG

Product: glycosyl transferase WecB/TagA/CpsF

Products: C55-PP-GlcNAc-ManNAcA; UDP [C]

Alternate protein names: UDP-ManNAcA transferase [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MTTADTRTGDLPPGVSYLGIAYSGLTLEQAAAALAARPAGAAFAYVVTPNAQHVVHLNRGEPFFTLAYRDAWLRLSDSRV
LAALTKLIGGPRLPVATGSDLTALLFQSVITADDPLVVIGGTAETDERLRAMFGLRHLVSHRPPMGVLRNPQAIAACVEF
IAAHPARFVFFAVGSPQSEVIAQHAFASGRATGSGLCIGGALLFLTGQVKRAPLWMRRLALEWLYRLLANPRGHFRRVFV
DSLPLVGLVLADRFKTRRSAK

Sequences:

>Translated_261_residues
MTTADTRTGDLPPGVSYLGIAYSGLTLEQAAAALAARPAGAAFAYVVTPNAQHVVHLNRGEPFFTLAYRDAWLRLSDSRV
LAALTKLIGGPRLPVATGSDLTALLFQSVITADDPLVVIGGTAETDERLRAMFGLRHLVSHRPPMGVLRNPQAIAACVEF
IAAHPARFVFFAVGSPQSEVIAQHAFASGRATGSGLCIGGALLFLTGQVKRAPLWMRRLALEWLYRLLANPRGHFRRVFV
DSLPLVGLVLADRFKTRRSAK
>Mature_260_residues
TTADTRTGDLPPGVSYLGIAYSGLTLEQAAAALAARPAGAAFAYVVTPNAQHVVHLNRGEPFFTLAYRDAWLRLSDSRVL
AALTKLIGGPRLPVATGSDLTALLFQSVITADDPLVVIGGTAETDERLRAMFGLRHLVSHRPPMGVLRNPQAIAACVEFI
AAHPARFVFFAVGSPQSEVIAQHAFASGRATGSGLCIGGALLFLTGQVKRAPLWMRRLALEWLYRLLANPRGHFRRVFVD
SLPLVGLVLADRFKTRRSAK

Specific function: Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA (Lipid II), the second lipid-linked intermediate involved in ECA synthesis [H]

COG id: COG1922

COG function: function code M; Teichoic acid biosynthesis proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023085
- InterPro:   IPR004629 [H]

Pfam domain/function: PF03808 Glyco_tran_WecB [H]

EC number: 2.4.1.- [C]

Molecular weight: Translated: 28092; Mature: 27961

Theoretical pI: Translated: 11.08; Mature: 11.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTADTRTGDLPPGVSYLGIAYSGLTLEQAAAALAARPAGAAFAYVVTPNAQHVVHLNRG
CCCCCCCCCCCCCCCHHHHHEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCC
EPFFTLAYRDAWLRLSDSRVLAALTKLIGGPRLPVATGSDLTALLFQSVITADDPLVVIG
CCEEEEEEECEEEEECCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEC
GTAETDERLRAMFGLRHLVSHRPPMGVLRNPQAIAACVEFIAAHPARFVFFAVGSPQSEV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
IAQHAFASGRATGSGLCIGGALLFLTGQVKRAPLWMRRLALEWLYRLLANPRGHFRRVFV
HHHHHHHCCCCCCCCEEHHHHHEEHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DSLPLVGLVLADRFKTRRSAK
HCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTADTRTGDLPPGVSYLGIAYSGLTLEQAAAALAARPAGAAFAYVVTPNAQHVVHLNRG
CCCCCCCCCCCCCCHHHHHEECCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCC
EPFFTLAYRDAWLRLSDSRVLAALTKLIGGPRLPVATGSDLTALLFQSVITADDPLVVIG
CCEEEEEEECEEEEECCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHCCCCCEEEEC
GTAETDERLRAMFGLRHLVSHRPPMGVLRNPQAIAACVEFIAAHPARFVFFAVGSPQSEV
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCHHHH
IAQHAFASGRATGSGLCIGGALLFLTGQVKRAPLWMRRLALEWLYRLLANPRGHFRRVFV
HHHHHHHCCCCCCCCEEHHHHHEEHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
DSLPLVGLVLADRFKTRRSAK
HCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-acetyl-D-mannosaminuronic-acid; undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate [C]

Specific reaction: UDP-N-acetyl-D-mannosaminuronic-acid + undecaprenyl-N-acetyl-alpha-D-glucosaminyl-pyrophosphate = C55-PP-GlcNAc-ManNAcA + UDP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA