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The map label for this gene is dnaQ [H]

Identifier: 83594940

GI number: 83594940

Start: 4150517

End: 4151209

Strand: Reverse

Name: dnaQ [H]

Synonym: Rru_A3611

Alternate gene names: 83594940

Gene position: 4151209-4150517 (Counterclockwise)

Preceding gene: 83594941

Following gene: 83594937

Centisome position: 95.37

GC content: 65.22

Gene sequence:

>693_bases
ATGCGTGAAATCGTTCTGGATACGGAAACCACCGGGCTGGATCCGGCGACCGGCGACCGGCTGGTGGAAATCGGCTGCAT
CGAGCTGATCAACCACATGCCGAGCGGCAATGACCTGCATCTTTACGTCAATCCCGAGCGCGACATGCCGCCCGAAGCCT
TCCGCGTTCATGGCCTGTCCGAGGCGTTTCTCGCCGATAAGCCGCTGTTTGCCGAGGTCGTCGACGAATTCCTGGCCTTT
ATCGGCGAGGATCGGCTGATCATCCATAACGCCGCCTTCGACATGAAATTCCTCAATGCCGAATTGGCCCGCCTGAAGCG
GCCGCCGCTGCCGATGAGCCGAGCGCTCGATACCCTGCGCATGGCCCAGGCGCGCTTTCCCGGGGCTCAGGCCAGTCTGG
ACGCCCTCTGTCGGCGTTTTGGCGTCGATACCTCGTCGCGCACCAAGCATGGCGCCCTGATCGACTGCGTGCTGCTGGCC
GAGGTTTATCTGGAACTGATCGGCGGGCGTGAGCCCGGGCTCGCCCTGTCGGCCGACAAGCGCCGCGACGGGGCGGCGGT
GCAGGTGGCCCGCCCGTTCCGCGCGCCACGGCCCCATGCCGCCAGCCCCGAAGAACTGGCCGCCCACGAGGAGTTTCTGA
AAAAGGTCAAGGATCCGATCTGGCGGCGCGACGCGCCCAATCCCCCGTCGTAA

Upstream 100 bases:

>100_bases
CTGGGGCCACGGCCGGCCTTGCGGGCCCTGCGCGCAAACCTCACAATGGCCCGATCGGGCGTGCGCCGCTGGCGCCGCGG
CAAGAGGACCTATCGACCCC

Downstream 100 bases:

>100_bases
CAACGGCGGCAGGAGAAAGTTTCCCGGCGTTTTGAGCAAATCCCAAGCGATCTGGACCGGATCGCGGCGACGATTTGCTT
GACGATCAAGATGGTGGAGC

Product: DNA polymerase III, subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MREIVLDTETTGLDPATGDRLVEIGCIELINHMPSGNDLHLYVNPERDMPPEAFRVHGLSEAFLADKPLFAEVVDEFLAF
IGEDRLIIHNAAFDMKFLNAELARLKRPPLPMSRALDTLRMAQARFPGAQASLDALCRRFGVDTSSRTKHGALIDCVLLA
EVYLELIGGREPGLALSADKRRDGAAVQVARPFRAPRPHAASPEELAAHEEFLKKVKDPIWRRDAPNPPS

Sequences:

>Translated_230_residues
MREIVLDTETTGLDPATGDRLVEIGCIELINHMPSGNDLHLYVNPERDMPPEAFRVHGLSEAFLADKPLFAEVVDEFLAF
IGEDRLIIHNAAFDMKFLNAELARLKRPPLPMSRALDTLRMAQARFPGAQASLDALCRRFGVDTSSRTKHGALIDCVLLA
EVYLELIGGREPGLALSADKRRDGAAVQVARPFRAPRPHAASPEELAAHEEFLKKVKDPIWRRDAPNPPS
>Mature_230_residues
MREIVLDTETTGLDPATGDRLVEIGCIELINHMPSGNDLHLYVNPERDMPPEAFRVHGLSEAFLADKPLFAEVVDEFLAF
IGEDRLIIHNAAFDMKFLNAELARLKRPPLPMSRALDTLRMAQARFPGAQASLDALCRRFGVDTSSRTKHGALIDCVLLA
EVYLELIGGREPGLALSADKRRDGAAVQVARPFRAPRPHAASPEELAAHEEFLKKVKDPIWRRDAPNPPS

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=236, Percent_Identity=42.7966101694915, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1788149, Length=167, Percent_Identity=29.940119760479, Blast_Score=70, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25491; Mature: 25491

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVLDTETTGLDPATGDRLVEIGCIELINHMPSGNDLHLYVNPERDMPPEAFRVHGLS
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCH
EAFLADKPLFAEVVDEFLAFIGEDRLIIHNAAFDMKFLNAELARLKRPPLPMSRALDTLR
HHHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MAQARFPGAQASLDALCRRFGVDTSSRTKHGALIDCVLLAEVYLELIGGREPGLALSADK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCC
RRDGAAVQVARPFRAPRPHAASPEELAAHEEFLKKVKDPIWRRDAPNPPS
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MREIVLDTETTGLDPATGDRLVEIGCIELINHMPSGNDLHLYVNPERDMPPEAFRVHGLS
CCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHCCCH
EAFLADKPLFAEVVDEFLAFIGEDRLIIHNAAFDMKFLNAELARLKRPPLPMSRALDTLR
HHHHCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MAQARFPGAQASLDALCRRFGVDTSSRTKHGALIDCVLLAEVYLELIGGREPGLALSADK
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCC
RRDGAAVQVARPFRAPRPHAASPEELAAHEEFLKKVKDPIWRRDAPNPPS
CCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]