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The map label for this gene is gcp

Identifier: 83594898

GI number: 83594898

Start: 4114465

End: 4115454

Strand: Direct

Name: gcp

Synonym: Rru_A3569

Alternate gene names: 83594898

Gene position: 4114465-4115454 (Clockwise)

Preceding gene: 83594893

Following gene: 83594899

Centisome position: 94.52

GC content: 72.02

Gene sequence:

>990_bases
ATGGCCGAAGCACTCCTCTCCCAGGTTGAGGAGCACCGCCCCTATGGCGGGGTCGTGCCCGAAATCGCCGCGCGCTCACA
CCTTGACCACGTGGACTCCCTGGTGATCCGCGCCCTTGGCGAGGCCGGGCTGACGGTTCACGACATCGACGCCGTCGCCG
CCACCGGCGGACCCGGGCTGATCGGCGGGGTGATCGTCGGCGTGATGACGGCCAAGGCCATCGCCCAGGTGGCGGGCAAG
CCGTTCATCGCCGTCAACCATCTGGAAGGCCACGCCCTGACCGTGCGGATGACCGCCGGCATCGATTTCCCCTATCTGCT
GCTTCTGGCCTCGGGCGGGCATTGCCAGCTTCTGGCGGTCGAGGGGGTGGGGCGGGCCAAGCGCCTGGGCACCACCATCG
ACGACGCCGCCGGCGAGGCCTTCGACAAGGTGGCCAAGATGCTGGGCCTGGGTTATCCGGGCGGACCGGCGGTGGAGCGG
GCGGCCCGGCGCGGCGATCCCCGGCGCTTTCGCCTGCCGCGCCCCCTGCTCGACCGCCCGGGCTGCGACCTGTCTTTCTC
GGGGCTGAAGACCGCCGTGCGCCAGACCGTGGAAAAGCTGCCGCCCGGGCCGTTGAGCGAGGGCGATATCGCCGATCTCT
GCGCCAGTTTCCAGGCCGCCGTCGCCGACTGTCTGGCCGACCGCTGCCGGGTGGCCGCCGGGATCTTCAGCGCCCGCCAT
GGCCGTGGCCGGCCGCTGGTGGTGGCCGGCGGCGTGGCGGCCAACGCCAGCTTGCGCGCCGCCCTGACCGAGGTCGCCCG
CCAAGCCGATATGACCTTCGTCGCCCCGCCCTTGGCGCTGTGCACCGACAACGCGGCGATGATCGCCTGGGTCGGCGTCG
AGCGCCTGCGCCTGGGGCTGGTCGACACCATGGACTTCAAACCCCGCCCGCGCTGGCCGCTCGACCCCGACGCGCCCAAG
GCGGCCGGAGCCGGAGGCGTAAAAGCTTAA

Upstream 100 bases:

>100_bases
AATGAGCATGCCCTTTCGCGTTCTCGGAATCGAGACAAGTTGTGACGAAACCGCCGCCGCGGTGGTCGAACCGGCCGCCG
ACGGGCGCGGTGGGCGAATT

Downstream 100 bases:

>100_bases
TAACATGCCGGAGGCGTGAAGGCGTAAAGACGCGCCGGAGGCGGGGAAGGGAAGGAGGCGGCGATGGTCAAGCCCGGTTT
ATACGAACGGGATTTCTATG

Product: O-sialoglycoprotein endopeptidase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MAEALLSQVEEHRPYGGVVPEIAARSHLDHVDSLVIRALGEAGLTVHDIDAVAATGGPGLIGGVIVGVMTAKAIAQVAGK
PFIAVNHLEGHALTVRMTAGIDFPYLLLLASGGHCQLLAVEGVGRAKRLGTTIDDAAGEAFDKVAKMLGLGYPGGPAVER
AARRGDPRRFRLPRPLLDRPGCDLSFSGLKTAVRQTVEKLPPGPLSEGDIADLCASFQAAVADCLADRCRVAAGIFSARH
GRGRPLVVAGGVAANASLRAALTEVARQADMTFVAPPLALCTDNAAMIAWVGVERLRLGLVDTMDFKPRPRWPLDPDAPK
AAGAGGVKA

Sequences:

>Translated_329_residues
MAEALLSQVEEHRPYGGVVPEIAARSHLDHVDSLVIRALGEAGLTVHDIDAVAATGGPGLIGGVIVGVMTAKAIAQVAGK
PFIAVNHLEGHALTVRMTAGIDFPYLLLLASGGHCQLLAVEGVGRAKRLGTTIDDAAGEAFDKVAKMLGLGYPGGPAVER
AARRGDPRRFRLPRPLLDRPGCDLSFSGLKTAVRQTVEKLPPGPLSEGDIADLCASFQAAVADCLADRCRVAAGIFSARH
GRGRPLVVAGGVAANASLRAALTEVARQADMTFVAPPLALCTDNAAMIAWVGVERLRLGLVDTMDFKPRPRWPLDPDAPK
AAGAGGVKA
>Mature_328_residues
AEALLSQVEEHRPYGGVVPEIAARSHLDHVDSLVIRALGEAGLTVHDIDAVAATGGPGLIGGVIVGVMTAKAIAQVAGKP
FIAVNHLEGHALTVRMTAGIDFPYLLLLASGGHCQLLAVEGVGRAKRLGTTIDDAAGEAFDKVAKMLGLGYPGGPAVERA
ARRGDPRRFRLPRPLLDRPGCDLSFSGLKTAVRQTVEKLPPGPLSEGDIADLCASFQAAVADCLADRCRVAAGIFSARHG
RGRPLVVAGGVAANASLRAALTEVARQADMTFVAPPLALCTDNAAMIAWVGVERLRLGLVDTMDFKPRPRWPLDPDAPKA
AGAGGVKA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=346, Percent_Identity=36.4161849710983, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI8923380, Length=290, Percent_Identity=31.3793103448276, Blast_Score=121, Evalue=7e-28,
Organism=Escherichia coli, GI1789445, Length=317, Percent_Identity=46.0567823343849, Blast_Score=254, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI17557464, Length=290, Percent_Identity=32.4137931034483, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71995670, Length=307, Percent_Identity=30.9446254071661, Blast_Score=104, Evalue=5e-23,
Organism=Saccharomyces cerevisiae, GI6320099, Length=324, Percent_Identity=31.4814814814815, Blast_Score=133, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=305, Percent_Identity=26.5573770491803, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20129063, Length=318, Percent_Identity=38.0503144654088, Blast_Score=180, Evalue=1e-45,
Organism=Drosophila melanogaster, GI21357207, Length=297, Percent_Identity=28.956228956229, Blast_Score=112, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_RHORT (Q2RND2)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428650.1
- ProteinModelPortal:   Q2RND2
- SMR:   Q2RND2
- STRING:   Q2RND2
- MEROPS:   M22.001
- GeneID:   3837025
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3569
- NMPDR:   fig|1085.1.peg.1928
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- BioCyc:   RRUB269796:RRU_A3569-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 34122; Mature: 33991

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEALLSQVEEHRPYGGVVPEIAARSHLDHVDSLVIRALGEAGLTVHDIDAVAATGGPGL
CHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCHH
IGGVIVGVMTAKAIAQVAGKPFIAVNHLEGHALTVRMTAGIDFPYLLLLASGGHCQLLAV
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHEEEEEECCCCEEEEEE
EGVGRAKRLGTTIDDAAGEAFDKVAKMLGLGYPGGPAVERAARRGDPRRFRLPRPLLDRP
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCHHCCC
GCDLSFSGLKTAVRQTVEKLPPGPLSEGDIADLCASFQAAVADCLADRCRVAAGIFSARH
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGRPLVVAGGVAANASLRAALTEVARQADMTFVAPPLALCTDNAAMIAWVGVERLRLGL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCEEEEEHHHHHHHHHH
VDTMDFKPRPRWPLDPDAPKAAGAGGVKA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AEALLSQVEEHRPYGGVVPEIAARSHLDHVDSLVIRALGEAGLTVHDIDAVAATGGPGL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCHH
IGGVIVGVMTAKAIAQVAGKPFIAVNHLEGHALTVRMTAGIDFPYLLLLASGGHCQLLAV
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCHHEEEEEECCCCEEEEEE
EGVGRAKRLGTTIDDAAGEAFDKVAKMLGLGYPGGPAVERAARRGDPRRFRLPRPLLDRP
CCCCHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEECCCCHHCCC
GCDLSFSGLKTAVRQTVEKLPPGPLSEGDIADLCASFQAAVADCLADRCRVAAGIFSARH
CCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GRGRPLVVAGGVAANASLRAALTEVARQADMTFVAPPLALCTDNAAMIAWVGVERLRLGL
CCCCEEEEECCCCCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCEEEEEHHHHHHHHHH
VDTMDFKPRPRWPLDPDAPKAAGAGGVKA
HHCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA