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The map label for this gene is mcpA [H]

Identifier: 83594892

GI number: 83594892

Start: 4105626

End: 4107317

Strand: Reverse

Name: mcpA [H]

Synonym: Rru_A3563

Alternate gene names: 83594892

Gene position: 4107317-4105626 (Counterclockwise)

Preceding gene: 83594894

Following gene: 83594890

Centisome position: 94.36

GC content: 55.44

Gene sequence:

>1692_bases
ATGATGTCCGTTATCAATAATATAAAAATCCCCATGAAACTGGCCGGTGCGTTTTTTACGCTCATTTTCATATTTTTGTT
CAGTGGCGTGATATCGCTTTACTTGATGAATGATATGGATGATGCAACAGCCGATATAACGGATAATTGGCACCTCACGA
TTACCAGCTTGGATAATATCGAAAAAACCCTGATTGAATACCGGCGTTGGGAACAAACCTTGGCTGCGGCAAGAACACCA
GATCAAAGTGATCGAGCCGATAAGATGCTTACCAAGACTCGTGTGGTGTTGTCGGAAATTTCTAAAAATCATTTGAAGTA
TCTTGCTAGTAAAAGAGAAGCTGATATTTATAATGAATTCGTTTCATATCTCCAGCCATTCTTTCAAGAAAGCGATAAGG
CCCGAGAATTTGCTAAAAAAGGCGATGCAAGCCAAGTAAATACCGTTCTCTTGGGCGAAAGCTATGTGATTATTGGAAAA
ATGCAAACGGTCCTGGATAGTCTTGTCCAACTGAACGCCGAGGGAATGAAAGCCGCGAACCAGCGGCAAGACGACAGCTA
TGAAACGGCCAAGATCGTCACTTATTTCGTCTTGACCTTCGCCACCATAATCGCCGTGCTAGCGGGTTTGATTTTACGAT
CGGCGATCGCCAAGCCGGTGTCGGCGATGACCGAGGCGATGAAGCGCTTGGCCGAGGGCGACAAGAGCATCGATATTCCG
GCAAGGGGGCGCCGCGACGAAATCGGCGCCATGGCTGAAGCCGTTCAGGTGTTCAAGGAGAACGCCATCCGCGCCGACCG
TTTGGCGGAGGATCAGCGCAAGGAGCAGGCCGCCCGCACGGCGCGCGCCCAAACTATCGAAACGCTGACGACGAATTTCG
ACGGTAAAATATCAAACCTGCTGACGCTGGTTGAGGGGGCTCTCACCGAACTCAACGCCACCGCCCAGACGATGCAGAGC
AATTCGGAACGGGCTAGCCAACAGGCCACGACCGTGGCTGCGGCATCGGAACAGGCCTCGACCAATGTTCAAACCGTGGC
CAGCGCCGCCGAGGAGCTTTCCAATGCCATCGTCGAGATCGGTCGTCAGGTCGAACGCTCGAGCGCGACATCGAAGGCGG
CCTCCGAAGAGGCGGAACGGACCAACAAGATCGTTCTTAGTCTGGCCGACAGCTCGCTCAAGATCGGTGACGTCATCGGC
CTGATCAATGATATCGCCAGCCAGACCAATCTTCTGGCGCTGAACGCCACGATCGAGGCGGCCCGCGCCGGCGACGCCGG
GAAAGGCTTCGCCGTGGTCGCCGGCGAGGTGAAATCCCTGGCCAATCAAACGGCCAAAGCCACCGAGGGAATTACCGCCC
AGATCGGCAGTGTCCAGTCGGCCACCCAGGAAGCGGTGACCGCCATTAACGGCATTTCAACCCGCATCGGCGAAATCAAC
GAGATTTCAACGGGGATCGCCGCCGCGGTCGAGGAACAATCGGCGGCGACGGGCGAAATCGCCCGAAATGCCCAGCAGGC
GGCCCAGGGAACCCAGGAGATTTCGGCCAATAACGCCGGCATGACCCAGACCTCCAGGGAAACCGGCGCGGCGTCGGGGC
GGGTGCTGTCCGCGGCTCAGGCCTTGGAAAAGGAAACCGCCAGTCTCAAGGACGTCGTCGCCAGCTTTTTGGACGGTGTG
CGATCGGCCTGA

Upstream 100 bases:

>100_bases
GGTTTCCGCTCCGCGGAGGCAAGGAGAAAGCCTGTCCGCGTTTCCAGAGGGTGGGTTAAGGGCGTTCGTGCATGATCTTT
ATAGGGTAAGGAGAAGCGTG

Downstream 100 bases:

>100_bases
GGTCCTCGCCCGCGGTCTTGGGCGGCACAAACGCAAAAGGGCTCTTTCCTATAAGGGAAGAGCCCCGCCGCCGCGCCCTC
CCGGCCAAGCCGGTGGTCAG

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MMSVINNIKIPMKLAGAFFTLIFIFLFSGVISLYLMNDMDDATADITDNWHLTITSLDNIEKTLIEYRRWEQTLAAARTP
DQSDRADKMLTKTRVVLSEISKNHLKYLASKREADIYNEFVSYLQPFFQESDKAREFAKKGDASQVNTVLLGESYVIIGK
MQTVLDSLVQLNAEGMKAANQRQDDSYETAKIVTYFVLTFATIIAVLAGLILRSAIAKPVSAMTEAMKRLAEGDKSIDIP
ARGRRDEIGAMAEAVQVFKENAIRADRLAEDQRKEQAARTARAQTIETLTTNFDGKISNLLTLVEGALTELNATAQTMQS
NSERASQQATTVAAASEQASTNVQTVASAAEELSNAIVEIGRQVERSSATSKAASEEAERTNKIVLSLADSSLKIGDVIG
LINDIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTAKATEGITAQIGSVQSATQEAVTAINGISTRIGEIN
EISTGIAAAVEEQSAATGEIARNAQQAAQGTQEISANNAGMTQTSRETGAASGRVLSAAQALEKETASLKDVVASFLDGV
RSA

Sequences:

>Translated_563_residues
MMSVINNIKIPMKLAGAFFTLIFIFLFSGVISLYLMNDMDDATADITDNWHLTITSLDNIEKTLIEYRRWEQTLAAARTP
DQSDRADKMLTKTRVVLSEISKNHLKYLASKREADIYNEFVSYLQPFFQESDKAREFAKKGDASQVNTVLLGESYVIIGK
MQTVLDSLVQLNAEGMKAANQRQDDSYETAKIVTYFVLTFATIIAVLAGLILRSAIAKPVSAMTEAMKRLAEGDKSIDIP
ARGRRDEIGAMAEAVQVFKENAIRADRLAEDQRKEQAARTARAQTIETLTTNFDGKISNLLTLVEGALTELNATAQTMQS
NSERASQQATTVAAASEQASTNVQTVASAAEELSNAIVEIGRQVERSSATSKAASEEAERTNKIVLSLADSSLKIGDVIG
LINDIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTAKATEGITAQIGSVQSATQEAVTAINGISTRIGEIN
EISTGIAAAVEEQSAATGEIARNAQQAAQGTQEISANNAGMTQTSRETGAASGRVLSAAQALEKETASLKDVVASFLDGV
RSA
>Mature_563_residues
MMSVINNIKIPMKLAGAFFTLIFIFLFSGVISLYLMNDMDDATADITDNWHLTITSLDNIEKTLIEYRRWEQTLAAARTP
DQSDRADKMLTKTRVVLSEISKNHLKYLASKREADIYNEFVSYLQPFFQESDKAREFAKKGDASQVNTVLLGESYVIIGK
MQTVLDSLVQLNAEGMKAANQRQDDSYETAKIVTYFVLTFATIIAVLAGLILRSAIAKPVSAMTEAMKRLAEGDKSIDIP
ARGRRDEIGAMAEAVQVFKENAIRADRLAEDQRKEQAARTARAQTIETLTTNFDGKISNLLTLVEGALTELNATAQTMQS
NSERASQQATTVAAASEQASTNVQTVASAAEELSNAIVEIGRQVERSSATSKAASEEAERTNKIVLSLADSSLKIGDVIG
LINDIASQTNLLALNATIEAARAGDAGKGFAVVAGEVKSLANQTAKATEGITAQIGSVQSATQEAVTAINGISTRIGEIN
EISTGIAAAVEEQSAATGEIARNAQQAAQGTQEISANNAGMTQTSRETGAASGRVLSAAQALEKETASLKDVVASFLDGV
RSA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788195, Length=188, Percent_Identity=36.1702127659575, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI2367378, Length=343, Percent_Identity=25.9475218658892, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI1788194, Length=345, Percent_Identity=29.8550724637681, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1789453, Length=331, Percent_Identity=29.0030211480363, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787690, Length=389, Percent_Identity=25.4498714652956, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60182; Mature: 60182

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSVINNIKIPMKLAGAFFTLIFIFLFSGVISLYLMNDMDDATADITDNWHLTITSLDNI
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHH
EKTLIEYRRWEQTLAAARTPDQSDRADKMLTKTRVVLSEISKNHLKYLASKREADIYNEF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSYLQPFFQESDKAREFAKKGDASQVNTVLLGESYVIIGKMQTVLDSLVQLNAEGMKAAN
HHHHHHHHHCCHHHHHHHHCCCCHHCCEEEECCCEEEEHHHHHHHHHHHHHCHHHHHHHC
QRQDDSYETAKIVTYFVLTFATIIAVLAGLILRSAIAKPVSAMTEAMKRLAEGDKSIDIP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARGRRDEIGAMAEAVQVFKENAIRADRLAEDQRKEQAARTARAQTIETLTTNFDGKISNL
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LTLVEGALTELNATAQTMQSNSERASQQATTVAAASEQASTNVQTVASAAEELSNAIVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRQVERSSATSKAASEEAERTNKIVLSLADSSLKIGDVIGLINDIASQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECHHHH
ARAGDAGKGFAVVAGEVKSLANQTAKATEGITAQIGSVQSATQEAVTAINGISTRIGEIN
HHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EISTGIAAAVEEQSAATGEIARNAQQAAQGTQEISANNAGMTQTSRETGAASGRVLSAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHCCCCCHHHHHHH
ALEKETASLKDVVASFLDGVRSA
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMSVINNIKIPMKLAGAFFTLIFIFLFSGVISLYLMNDMDDATADITDNWHLTITSLDNI
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECHHHH
EKTLIEYRRWEQTLAAARTPDQSDRADKMLTKTRVVLSEISKNHLKYLASKREADIYNEF
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSYLQPFFQESDKAREFAKKGDASQVNTVLLGESYVIIGKMQTVLDSLVQLNAEGMKAAN
HHHHHHHHHCCHHHHHHHHCCCCHHCCEEEECCCEEEEHHHHHHHHHHHHHCHHHHHHHC
QRQDDSYETAKIVTYFVLTFATIIAVLAGLILRSAIAKPVSAMTEAMKRLAEGDKSIDIP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ARGRRDEIGAMAEAVQVFKENAIRADRLAEDQRKEQAARTARAQTIETLTTNFDGKISNL
CCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LTLVEGALTELNATAQTMQSNSERASQQATTVAAASEQASTNVQTVASAAEELSNAIVEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GRQVERSSATSKAASEEAERTNKIVLSLADSSLKIGDVIGLINDIASQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECHHHH
ARAGDAGKGFAVVAGEVKSLANQTAKATEGITAQIGSVQSATQEAVTAINGISTRIGEIN
HHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCHH
EISTGIAAAVEEQSAATGEIARNAQQAAQGTQEISANNAGMTQTSRETGAASGRVLSAAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCHHHCCCCCHHHHHHH
ALEKETASLKDVVASFLDGVRSA
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]