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The map label for this gene is aer [C]

Identifier: 83594825

GI number: 83594825

Start: 4024109

End: 4026214

Strand: Reverse

Name: aer [C]

Synonym: Rru_A3496

Alternate gene names: 83594825

Gene position: 4026214-4024109 (Counterclockwise)

Preceding gene: 83594828

Following gene: 83594821

Centisome position: 92.5

GC content: 69.75

Gene sequence:

>2106_bases
ATGAAAGCCTCGTTCGCCACGGCCTATTCGCCTTCCGGGGGGATGGAGCGGTCCTTCGCTTCTCCCCCCTCCCCCTCGGC
CGCCTCTTCCGGTCGTGGCCGGTTTCTGGCACGGCTGAACCGCTCACCCTTGGCCGGGTTTTCCATCCCGATCGGCGCGC
GGATGGTGATTTTGGTGCTGCTTGGGCTTTTGGCTTTCGGCGGCGCCGTCGCCATCCATTTCGTCAGCGAGGCGGCCAGC
CGCGAGATCGAGGACCGCCGCGCCGTGCTGCGCGACATCGATCTTGGGGTCAAGGATATCGCCCTCAACGTCGCCGGCCT
GCGGCTGGCCCATCAGTCCTACGCCACCGAACGCGCCGAGGCGGTGGCCCGCTTCCGCGCGCTGGCCGAAGCCGCGCGGG
GCGATCTCGGCCGGGTCGGCGTTCTGGCGGCGGCCGCCGGGATCGGCGAGGCGGGTAAGCCGACGCTCGATCGCCTGATG
ACCGGGGCCGCCGCCTTGGAGGCCAAGATGGCCACGGCCGCCGCCGCCCAGGAAACCCTGGGCGTGGGCGAAGGCGAAGG
GCTGCGCGGTCACTTGTCCGGGGTGATCGCCGGCATCGAGGGCGAGCTTGCCCAATGGCCCAATGTCGGCCAGATCGCCG
TCAAGCTGGCCCAGGTCAAGCGCTTTGAACAGGGCTTTCTGATCGCCCCCGGGCCGGACGCCTTGGGCCGCTTGCGCAAG
GCCGCCAATGAATTCGACTTCGCCCTGATGGGCGGGCCTTTTGACGCCGATACGGCGACGCGGCTGTCCTCGGCGGTGGG
CGCCTATACCAAGGGGCTGACCGGCTATATCGCCGCCGTCGAAACCAGCAAGGCCGCCGGCGCCACCCTGACCGCCGCCC
TTGACGCTTTTGAGCGCGATCTGGCCGAGATCGTCGCCCTCGCCGATCAGGAAACCACCCTGGCCCGCCAGCGCTTCGTG
GAAACCCGCGCCCATATGCTGACCTTGCTGTCGTGGGGCGGGGGCGGCTTGCTGGTGCTGTTCGTTCTGGCCTCCGCTTT
GGTCGGCCAGTCGATCTATCGCCCTCTCGGGCGGATCGAACGGACGATGCTGGCCCTGGCCGCCGGGGAAAGCGACGTCG
AGGTGCCCGGACTCGGGCGTCGCGATGAAATCGGCCGCATGGCCGAGGCGGTCGCCGTTTTCAAGCGCAACGCCGCCGAG
GTTGATCGCTTGCATGCCGAGCGCCGGCGCGAGGGGGAAGAGGCCGAACGCCACCGGCGCGCCGCCCTGCTTGATCTGGC
CGATGGCTTCGAGCGCAGCGTCCGCCACCTCGCCACCGATCTTGACCGCGCGGCCCATCTGATCACCGACAAGGGGCGGC
GCATGGCCGACGAGGCCGGCGAAACCGACGAGGCCGGACGCGGCGTCGCCGATCTGATCGCCGCCGCCGCCCAAACCCTG
GCCGAGGTGGTGACGAGCGCCCATGAACTGGTGCGCTCGGCCGGGCTGGCGCGCGATCATCTGGCCCAATCGCAAAGCGC
CATCACCGGCGCCCTTGCCGAAACCACCGAGGCCGAAAGCCGCGTCGCCGCCCTGTCGGCGGCGGCCGAGCGCATCGGTC
AGGTGGTCGATCTGATCACCAGCGTCGCCGCCCAGACCAATCTTCTGGCGCTCAACGCCACCATCGAAGCCGCCCGCGCC
GGCGCGGCGGGCAAGGGCTTCGCCGTGGTCGCCGGCGAGGTCAAGACCCTTGCCCAGCAGACCAACCGGGCAACCGAGGA
AATCGCCGGCCATGTCGAGGATATCCGCCAAGCCATCGCCGGAACGGTCGAGGGTATCGGTCATATCTCCAGCGAGGTCG
GCCGGGTCTCGGGTTTGACCGAGGCCCTGTCGGCGGCGGTCGGCGCCCAGGAGGTGGCCATCGGCGGCATCGGCCAGGCC
CTGGACGGCACGGCGGCGACGATGACGACGGTTACGGGCAATCTGGAGCGCATGGGCGCAGTGATGGCGCGCTCGGCCCG
CTCGGCGCTGGAACTGCGCGAAACCGCCGAGGGGTTGGCCGATCAGAGCGCCGGCCTGGAACGCGAGCTCGATGGCTTTC
TCGAACGGATTCGCGGAACAAGTTGA

Upstream 100 bases:

>100_bases
CATTACCCTCCGAACCCCGGTGCTACGGTCCGCGCCAACCCGATGGCCAGCGTATCGCTGGGCGCGTCGTTTCATTTTCC
CGTTGCCCCATAGGGTGCCC

Downstream 100 bases:

>100_bases
GAATTAGCGTCACTTCGCAACCCGTTTGCAAAACAAGATGCATTTTGCAACAAGGGGTTCAGGCACCCGGACGGGTGCAA
ACGAAAAGGGAAATATGCGA

Product: chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MKASFATAYSPSGGMERSFASPPSPSAASSGRGRFLARLNRSPLAGFSIPIGARMVILVLLGLLAFGGAVAIHFVSEAAS
REIEDRRAVLRDIDLGVKDIALNVAGLRLAHQSYATERAEAVARFRALAEAARGDLGRVGVLAAAAGIGEAGKPTLDRLM
TGAAALEAKMATAAAAQETLGVGEGEGLRGHLSGVIAGIEGELAQWPNVGQIAVKLAQVKRFEQGFLIAPGPDALGRLRK
AANEFDFALMGGPFDADTATRLSSAVGAYTKGLTGYIAAVETSKAAGATLTAALDAFERDLAEIVALADQETTLARQRFV
ETRAHMLTLLSWGGGGLLVLFVLASALVGQSIYRPLGRIERTMLALAAGESDVEVPGLGRRDEIGRMAEAVAVFKRNAAE
VDRLHAERRREGEEAERHRRAALLDLADGFERSVRHLATDLDRAAHLITDKGRRMADEAGETDEAGRGVADLIAAAAQTL
AEVVTSAHELVRSAGLARDHLAQSQSAITGALAETTEAESRVAALSAAAERIGQVVDLITSVAAQTNLLALNATIEAARA
GAAGKGFAVVAGEVKTLAQQTNRATEEIAGHVEDIRQAIAGTVEGIGHISSEVGRVSGLTEALSAAVGAQEVAIGGIGQA
LDGTAATMTTVTGNLERMGAVMARSARSALELRETAEGLADQSAGLERELDGFLERIRGTS

Sequences:

>Translated_701_residues
MKASFATAYSPSGGMERSFASPPSPSAASSGRGRFLARLNRSPLAGFSIPIGARMVILVLLGLLAFGGAVAIHFVSEAAS
REIEDRRAVLRDIDLGVKDIALNVAGLRLAHQSYATERAEAVARFRALAEAARGDLGRVGVLAAAAGIGEAGKPTLDRLM
TGAAALEAKMATAAAAQETLGVGEGEGLRGHLSGVIAGIEGELAQWPNVGQIAVKLAQVKRFEQGFLIAPGPDALGRLRK
AANEFDFALMGGPFDADTATRLSSAVGAYTKGLTGYIAAVETSKAAGATLTAALDAFERDLAEIVALADQETTLARQRFV
ETRAHMLTLLSWGGGGLLVLFVLASALVGQSIYRPLGRIERTMLALAAGESDVEVPGLGRRDEIGRMAEAVAVFKRNAAE
VDRLHAERRREGEEAERHRRAALLDLADGFERSVRHLATDLDRAAHLITDKGRRMADEAGETDEAGRGVADLIAAAAQTL
AEVVTSAHELVRSAGLARDHLAQSQSAITGALAETTEAESRVAALSAAAERIGQVVDLITSVAAQTNLLALNATIEAARA
GAAGKGFAVVAGEVKTLAQQTNRATEEIAGHVEDIRQAIAGTVEGIGHISSEVGRVSGLTEALSAAVGAQEVAIGGIGQA
LDGTAATMTTVTGNLERMGAVMARSARSALELRETAEGLADQSAGLERELDGFLERIRGTS
>Mature_701_residues
MKASFATAYSPSGGMERSFASPPSPSAASSGRGRFLARLNRSPLAGFSIPIGARMVILVLLGLLAFGGAVAIHFVSEAAS
REIEDRRAVLRDIDLGVKDIALNVAGLRLAHQSYATERAEAVARFRALAEAARGDLGRVGVLAAAAGIGEAGKPTLDRLM
TGAAALEAKMATAAAAQETLGVGEGEGLRGHLSGVIAGIEGELAQWPNVGQIAVKLAQVKRFEQGFLIAPGPDALGRLRK
AANEFDFALMGGPFDADTATRLSSAVGAYTKGLTGYIAAVETSKAAGATLTAALDAFERDLAEIVALADQETTLARQRFV
ETRAHMLTLLSWGGGGLLVLFVLASALVGQSIYRPLGRIERTMLALAAGESDVEVPGLGRRDEIGRMAEAVAVFKRNAAE
VDRLHAERRREGEEAERHRRAALLDLADGFERSVRHLATDLDRAAHLITDKGRRMADEAGETDEAGRGVADLIAAAAQTL
AEVVTSAHELVRSAGLARDHLAQSQSAITGALAETTEAESRVAALSAAAERIGQVVDLITSVAAQTNLLALNATIEAARA
GAAGKGFAVVAGEVKTLAQQTNRATEEIAGHVEDIRQAIAGTVEGIGHISSEVGRVSGLTEALSAAVGAQEVAIGGIGQA
LDGTAATMTTVTGNLERMGAVMARSARSALELRETAEGLADQSAGLERELDGFLERIRGTS

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=312, Percent_Identity=26.6025641025641, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787690, Length=170, Percent_Identity=35.2941176470588, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367378, Length=124, Percent_Identity=38.7096774193548, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788195, Length=200, Percent_Identity=30, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788194, Length=128, Percent_Identity=36.71875, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 72637; Mature: 72637

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASFATAYSPSGGMERSFASPPSPSAASSGRGRFLARLNRSPLAGFSIPIGARMVILVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHH
LGLLAFGGAVAIHFVSEAASREIEDRRAVLRDIDLGVKDIALNVAGLRLAHQSYATERAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVARFRALAEAARGDLGRVGVLAAAAGIGEAGKPTLDRLMTGAAALEAKMATAAAAQETL
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGEGEGLRGHLSGVIAGIEGELAQWPNVGQIAVKLAQVKRFEQGFLIAPGPDALGRLRK
CCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHH
AANEFDFALMGGPFDADTATRLSSAVGAYTKGLTGYIAAVETSKAAGATLTAALDAFERD
HHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCHHHHHHHHHHHHH
LAEIVALADQETTLARQRFVETRAHMLTLLSWGGGGLLVLFVLASALVGQSIYRPLGRIE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RTMLALAAGESDVEVPGLGRRDEIGRMAEAVAVFKRNAAEVDRLHAERRREGEEAERHRR
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHH
AALLDLADGFERSVRHLATDLDRAAHLITDKGRRMADEAGETDEAGRGVADLIAAAAQTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AEVVTSAHELVRSAGLARDHLAQSQSAITGALAETTEAESRVAALSAAAERIGQVVDLIT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAQTNLLALNATIEAARAGAAGKGFAVVAGEVKTLAQQTNRATEEIAGHVEDIRQAIA
HHHHHHCEEEEECHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTVEGIGHISSEVGRVSGLTEALSAAVGAQEVAIGGIGQALDGTAATMTTVTGNLERMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHCCCCHHHHHHHHCCHHHHHH
VMARSARSALELRETAEGLADQSAGLERELDGFLERIRGTS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKASFATAYSPSGGMERSFASPPSPSAASSGRGRFLARLNRSPLAGFSIPIGARMVILVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHH
LGLLAFGGAVAIHFVSEAASREIEDRRAVLRDIDLGVKDIALNVAGLRLAHQSYATERAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AVARFRALAEAARGDLGRVGVLAAAAGIGEAGKPTLDRLMTGAAALEAKMATAAAAQETL
HHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVGEGEGLRGHLSGVIAGIEGELAQWPNVGQIAVKLAQVKRFEQGFLIAPGPDALGRLRK
CCCCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCEEECCCHHHHHHHHH
AANEFDFALMGGPFDADTATRLSSAVGAYTKGLTGYIAAVETSKAAGATLTAALDAFERD
HHHHCCEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHEEECCCCCCHHHHHHHHHHHHH
LAEIVALADQETTLARQRFVETRAHMLTLLSWGGGGLLVLFVLASALVGQSIYRPLGRIE
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RTMLALAAGESDVEVPGLGRRDEIGRMAEAVAVFKRNAAEVDRLHAERRREGEEAERHRR
HHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHH
AALLDLADGFERSVRHLATDLDRAAHLITDKGRRMADEAGETDEAGRGVADLIAAAAQTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHH
AEVVTSAHELVRSAGLARDHLAQSQSAITGALAETTEAESRVAALSAAAERIGQVVDLIT
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SVAAQTNLLALNATIEAARAGAAGKGFAVVAGEVKTLAQQTNRATEEIAGHVEDIRQAIA
HHHHHHCEEEEECHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTVEGIGHISSEVGRVSGLTEALSAAVGAQEVAIGGIGQALDGTAATMTTVTGNLERMGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHCCCCHHHHHHHHCCHHHHHH
VMARSARSALELRETAEGLADQSAGLERELDGFLERIRGTS
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]