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The map label for this gene is trpB [H]

Identifier: 83594756

GI number: 83594756

Start: 3944688

End: 3945914

Strand: Direct

Name: trpB [H]

Synonym: Rru_A3427

Alternate gene names: 83594756

Gene position: 3944688-3945914 (Clockwise)

Preceding gene: 83594755

Following gene: 83594757

Centisome position: 90.62

GC content: 66.01

Gene sequence:

>1227_bases
ATGACCACCATGCCAAACACCTACCGCTCCGGCCCCGATGATCGCGGTCATTTCGGACTGCACGGCGGGCGCTATGTCGC
CGAAACCCTGATGCCGCTGATCCTCGATCTGGAAAAGGCTTGGGAAGCGACCCGCGATGATCCGGCGTTCAAGGCCGAGC
TGGGCGGCTATCTCGCCACCTATGTCGGCCGGCCGAGCCCGCTGTACTTCGCCCGCCGTCTGACCGAGGCCCTGGGCGGG
GCAAAGATCTATTTCAAGCGCGAAGACCTCAACCATACGGGCGCCCATAAGATCAACAATTGCATGGGGCAGATCCTGCT
CGCCAGGCGCATGGGCAAGACGCGGATCATCGCCGAAACCGGCGCCGGCCAGCATGGGGTGGCCACCGCCACCGTCTGCG
CCCTGTTTGGCATGCCCTGCGTGATTTACATGGGCGCCACCGATATCGAGCGTCAGGCGCCCAATGTGTTCCGCATGAAG
CTGCTTGGCGCCGAGGTCCGCCCGGTGACCAGCGGCGCGGGCACCCTCAAGGACGCGATGAACGACGCCATGCGCGACTG
GGTCGCCAATGTCGCCGACACCTATTACCTGATCGGCACGGCGGCCGGCCCCCATCCCTATCCGGCGATGGTCCGCGACC
TGCAGAAGGTCATCGGCGAGGAAGCCCGCGCCCAGGTGCTCGAGGCCGAGGGTCGGCTGCCCGACACCCTGATCGCCTGC
ATCGGCGGCGGCTCCAACGCCATCGGCCTGTTCCACCCCTTCCTGGACGATCCCGACGTGCGCATCATCGGTGTCGAGGC
CGCCGGCGAGGGCTTGGACAAGCGCCATGCCGCCTCAATGGCCGGGGGGCGTCTGGGCGTGCTGCATGGCAACCGCACCT
ATCTGCTTCAGGACGGCGCCGGCCAGATCACCGAGGCCCATTCGATTTCCGCCGGCCTGGATTATCCCGGCGTCGGCCCC
GAGCACGCCTGGCTCAAGGACAGCGGCCGGGTCGAGTATGTGCCGATCACCGACGACGAGGCGGTTCACGCCTTCCAGGA
AACCACCAAGCTCGAAGGGATCATTCCGGCCCTGGAAAGCAGCCACGCCATCGCCCATGCCATGAAGATCGCCCCCACCC
TGCCGGCCGATCATCTGATGGTGGTCAGCCTGTCGGGGCGCGGCGACAAGGACGTGGGGACGATCGCCAAGGTTCTGGGC
AGTGATTTCAAGGGAATGATGCCGTGA

Upstream 100 bases:

>100_bases
CTCTTGGCGCCGGCCCGACGGGGCCGCATAAAAGAGCGGCGCTCTTGGCGCCGGGTGATGGGCTGCGCTATAACCAGCAC
CCGCCAGGAAGGGATCTCCG

Downstream 100 bases:

>100_bases
GCGCCACCACGCCGACCACCGATCGCCTCTCCCGCCGCTTCGCCGCCCTCAAGGCCGAAGGCCGGGGGGGCCTTGTCACC
TATGTCATGGCCGGCGATCC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MTTMPNTYRSGPDDRGHFGLHGGRYVAETLMPLILDLEKAWEATRDDPAFKAELGGYLATYVGRPSPLYFARRLTEALGG
AKIYFKREDLNHTGAHKINNCMGQILLARRMGKTRIIAETGAGQHGVATATVCALFGMPCVIYMGATDIERQAPNVFRMK
LLGAEVRPVTSGAGTLKDAMNDAMRDWVANVADTYYLIGTAAGPHPYPAMVRDLQKVIGEEARAQVLEAEGRLPDTLIAC
IGGGSNAIGLFHPFLDDPDVRIIGVEAAGEGLDKRHAASMAGGRLGVLHGNRTYLLQDGAGQITEAHSISAGLDYPGVGP
EHAWLKDSGRVEYVPITDDEAVHAFQETTKLEGIIPALESSHAIAHAMKIAPTLPADHLMVVSLSGRGDKDVGTIAKVLG
SDFKGMMP

Sequences:

>Translated_408_residues
MTTMPNTYRSGPDDRGHFGLHGGRYVAETLMPLILDLEKAWEATRDDPAFKAELGGYLATYVGRPSPLYFARRLTEALGG
AKIYFKREDLNHTGAHKINNCMGQILLARRMGKTRIIAETGAGQHGVATATVCALFGMPCVIYMGATDIERQAPNVFRMK
LLGAEVRPVTSGAGTLKDAMNDAMRDWVANVADTYYLIGTAAGPHPYPAMVRDLQKVIGEEARAQVLEAEGRLPDTLIAC
IGGGSNAIGLFHPFLDDPDVRIIGVEAAGEGLDKRHAASMAGGRLGVLHGNRTYLLQDGAGQITEAHSISAGLDYPGVGP
EHAWLKDSGRVEYVPITDDEAVHAFQETTKLEGIIPALESSHAIAHAMKIAPTLPADHLMVVSLSGRGDKDVGTIAKVLG
SDFKGMMP
>Mature_407_residues
TTMPNTYRSGPDDRGHFGLHGGRYVAETLMPLILDLEKAWEATRDDPAFKAELGGYLATYVGRPSPLYFARRLTEALGGA
KIYFKREDLNHTGAHKINNCMGQILLARRMGKTRIIAETGAGQHGVATATVCALFGMPCVIYMGATDIERQAPNVFRMKL
LGAEVRPVTSGAGTLKDAMNDAMRDWVANVADTYYLIGTAAGPHPYPAMVRDLQKVIGEEARAQVLEAEGRLPDTLIACI
GGGSNAIGLFHPFLDDPDVRIIGVEAAGEGLDKRHAASMAGGRLGVLHGNRTYLLQDGAGQITEAHSISAGLDYPGVGPE
HAWLKDSGRVEYVPITDDEAVHAFQETTKLEGIIPALESSHAIAHAMKIAPTLPADHLMVVSLSGRGDKDVGTIAKVLGS
DFKGMMP

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=401, Percent_Identity=54.3640897755611, Blast_Score=439, Evalue=1e-124,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=54.1666666666667, Blast_Score=440, Evalue=1e-124,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43681; Mature: 43549

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMPNTYRSGPDDRGHFGLHGGRYVAETLMPLILDLEKAWEATRDDPAFKAELGGYLAT
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHH
YVGRPSPLYFARRLTEALGGAKIYFKREDLNHTGAHKINNCMGQILLARRMGKTRIIAET
HCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GAGQHGVATATVCALFGMPCVIYMGATDIERQAPNVFRMKLLGAEVRPVTSGAGTLKDAM
CCCCCCHHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEHHHHCCCCCCCCCCCHHHHHHH
NDAMRDWVANVADTYYLIGTAAGPHPYPAMVRDLQKVIGEEARAQVLEAEGRLPDTLIAC
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEE
IGGGSNAIGLFHPFLDDPDVRIIGVEAAGEGLDKRHAASMAGGRLGVLHGNRTYLLQDGA
ECCCCCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCEEEEEECCC
GQITEAHSISAGLDYPGVGPEHAWLKDSGRVEYVPITDDEAVHAFQETTKLEGIIPALES
CCCCHHHCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
SHAIAHAMKIAPTLPADHLMVVSLSGRGDKDVGTIAKVLGSDFKGMMP
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TTMPNTYRSGPDDRGHFGLHGGRYVAETLMPLILDLEKAWEATRDDPAFKAELGGYLAT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHH
YVGRPSPLYFARRLTEALGGAKIYFKREDLNHTGAHKINNCMGQILLARRMGKTRIIAET
HCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEC
GAGQHGVATATVCALFGMPCVIYMGATDIERQAPNVFRMKLLGAEVRPVTSGAGTLKDAM
CCCCCCHHHHHHHHHHCCCEEEEECCCHHHHCCCCCEEHHHHCCCCCCCCCCCHHHHHHH
NDAMRDWVANVADTYYLIGTAAGPHPYPAMVRDLQKVIGEEARAQVLEAEGRLPDTLIAC
HHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEE
IGGGSNAIGLFHPFLDDPDVRIIGVEAAGEGLDKRHAASMAGGRLGVLHGNRTYLLQDGA
ECCCCCCEEEECCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEECCEEEEEECCC
GQITEAHSISAGLDYPGVGPEHAWLKDSGRVEYVPITDDEAVHAFQETTKLEGIIPALES
CCCCHHHCCCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHC
SHAIAHAMKIAPTLPADHLMVVSLSGRGDKDVGTIAKVLGSDFKGMMP
CHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA