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The map label for this gene is omp38 [H]

Identifier: 83594714

GI number: 83594714

Start: 3902293

End: 3903021

Strand: Direct

Name: omp38 [H]

Synonym: Rru_A3385

Alternate gene names: 83594714

Gene position: 3902293-3903021 (Clockwise)

Preceding gene: 83594713

Following gene: 83594715

Centisome position: 89.65

GC content: 70.78

Gene sequence:

>729_bases
ATGAAGGGCAATTCGCTGTGGACGATTCTGGCCGGCGCCTGGTTGGCTGGCGGCGGCATCGCCTCCCTTGGCTTCGGTCC
CGACAGGCTTCATCCGACCGCCTTGACCGGCGACGGCGGCGAGGTGCGGCTGCGCTATGCCGTGGTCGAAACCGGAAAAC
CCGGCACGGCGCTGTTTGACGCCTATGGCGCGGCCTTGCGGCGGGCCGGATTCGAGATTTCGCCCACTCATCAGGCGCCC
CCCCGCCTGCGCGCCCATCTTGACGGCCCCGATGGCCCCTTGCGGGCGGTGCTGACCCTTACCCAAGACTCCGAAAGCGC
CGGAACACCCCTTCATGTCTCGCTGACGGCGGCGCCGACCGATGCCGTGACGGTGGGGGGCACGGTCACCCCACCCTCGC
CGCGCCCCAGTCTTCATTTCGCCAGCGATCAGGCCGATCTTGACGACGACGCCGGCCCTTTGCTGGCCGAGGCGGCCCGC
GTGCTGAAACAAGATCCCCGGCTGTCGCTGATGGTGATGGGCCATACGGACGACCGCCACGCCCTGGATGAGGCCCTCGA
CCTGTCGGCGCGGCGGGCCGAGGCGGTGGTCGCCGCCCTGGTCGAGGACCACGGTGTCGAGCGCGGGCGCCTTGTCCCCC
GGGGGGCCGGTTGGCTGGCGCCCGTGGCGTCGAACCGCACCCAGGCCGGGCGGGCCCTCAACCGCCGGGTCGATCTGGCC
GAGATATGA

Upstream 100 bases:

>100_bases
GGCGCTCTGGATCCGCGACGCCCGGCGCTCCAGTTAGGCGGCGGGGTGAGGTCGGCGGCCAAGGGGCTTGGCCGTCTGGT
TTCGCGGGAGCGTGAGGTCG

Downstream 100 bases:

>100_bases
GACCGCCCGTTTGCGCGGCCTGGACGCGGCACGCGTCGGTTCGGTCTGGACGCGGCACGCGTCGGTTCGGTCTGGACGCG
GCACGCGTCGGTTCGGTCTG

Product: OmpA/MotB

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MKGNSLWTILAGAWLAGGGIASLGFGPDRLHPTALTGDGGEVRLRYAVVETGKPGTALFDAYGAALRRAGFEISPTHQAP
PRLRAHLDGPDGPLRAVLTLTQDSESAGTPLHVSLTAAPTDAVTVGGTVTPPSPRPSLHFASDQADLDDDAGPLLAEAAR
VLKQDPRLSLMVMGHTDDRHALDEALDLSARRAEAVVAALVEDHGVERGRLVPRGAGWLAPVASNRTQAGRALNRRVDLA
EI

Sequences:

>Translated_242_residues
MKGNSLWTILAGAWLAGGGIASLGFGPDRLHPTALTGDGGEVRLRYAVVETGKPGTALFDAYGAALRRAGFEISPTHQAP
PRLRAHLDGPDGPLRAVLTLTQDSESAGTPLHVSLTAAPTDAVTVGGTVTPPSPRPSLHFASDQADLDDDAGPLLAEAAR
VLKQDPRLSLMVMGHTDDRHALDEALDLSARRAEAVVAALVEDHGVERGRLVPRGAGWLAPVASNRTQAGRALNRRVDLA
EI
>Mature_242_residues
MKGNSLWTILAGAWLAGGGIASLGFGPDRLHPTALTGDGGEVRLRYAVVETGKPGTALFDAYGAALRRAGFEISPTHQAP
PRLRAHLDGPDGPLRAVLTLTQDSESAGTPLHVSLTAAPTDAVTVGGTVTPPSPRPSLHFASDQADLDDDAGPLLAEAAR
VLKQDPRLSLMVMGHTDDRHALDEALDLSARRAEAVVAALVEDHGVERGRLVPRGAGWLAPVASNRTQAGRALNRRVDLA
EI

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=103, Percent_Identity=36.8932038834951, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 25278; Mature: 25278

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00178 AA_TRNA_LIGASE_I ; PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGNSLWTILAGAWLAGGGIASLGFGPDRLHPTALTGDGGEVRLRYAVVETGKPGTALFD
CCCCEEEEEEEHHHHCCCCEEECCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCHHHHH
AYGAALRRAGFEISPTHQAPPRLRAHLDGPDGPLRAVLTLTQDSESAGTPLHVSLTAAPT
HHHHHHHHCCCEECCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCC
DAVTVGGTVTPPSPRPSLHFASDQADLDDDAGPLLAEAARVLKQDPRLSLMVMGHTDDRH
CEEEECCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHH
ALDEALDLSARRAEAVVAALVEDHGVERGRLVPRGAGWLAPVASNRTQAGRALNRRVDLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHH
EI
CC
>Mature Secondary Structure
MKGNSLWTILAGAWLAGGGIASLGFGPDRLHPTALTGDGGEVRLRYAVVETGKPGTALFD
CCCCEEEEEEEHHHHCCCCEEECCCCCCCCCCEEEECCCCCEEEEEEEEECCCCCHHHHH
AYGAALRRAGFEISPTHQAPPRLRAHLDGPDGPLRAVLTLTQDSESAGTPLHVSLTAAPT
HHHHHHHHCCCEECCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCC
DAVTVGGTVTPPSPRPSLHFASDQADLDDDAGPLLAEAARVLKQDPRLSLMVMGHTDDRH
CEEEECCEECCCCCCCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCHH
ALDEALDLSARRAEAVVAALVEDHGVERGRLVPRGAGWLAPVASNRTQAGRALNRRVDLA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHH
EI
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA