Click here to switch to the map view.

The map label for this gene is cobM [H]

Identifier: 83594713

GI number: 83594713

Start: 3901411

End: 3902172

Strand: Direct

Name: cobM [H]

Synonym: Rru_A3384

Alternate gene names: 83594713

Gene position: 3901411-3902172 (Clockwise)

Preceding gene: 83594712

Following gene: 83594714

Centisome position: 89.63

GC content: 68.9

Gene sequence:

>762_bases
ATGACCGTCCATTTCATCGGCGCCGGTCCCGGCGCCCCCGATCTGATCACCCTGCGCGGGCTGAGGCTGATCCAGTCCTG
CCCCGTGGTGCTGTTCGCCGGTAGCTTGATCCCGCGCGAGGTGGTGGCCGAGGCCGGGGCGGAGGCGCGGGTGATCGATT
CCTCGGCCCTACATCTTGATGAGATCATCGCGGTGATGGCCGAGGCCACGGCGCGCGGCGAGGATATCGCCCGCCTGCAT
TCGGGCGATCCCAGCCTGTATGGGGCGATCGCCGAGCAGATCCGCCGCTTGCGCGGCCTGGGGATCGCCTATGACATCTG
CCCGGGCGTGCCGTCCTATGCGGCGGCGGCGGCGGCCCTTGGCAATGAGCTGACCCTGCCCGAGGTCTGCCAGACGGTGA
TCCTCACCCGTACCTCGGTCCGCGCCTCGCCGATGCCCGCCGGCGAGGATCTGGAAAGCCTGGGGCGGAGCGGCGCCCTG
CTCGCCATCCATCTATCGATCGCCAATCTGGCCGAGGTCGAAGCCAAACTGACCCCGCTTTATGGCGCCGATTGCCCGGT
GGCGGTGGTCTATCGGGCAAGCTGGCCCGATCAGACGGTGGTACGCGGCACCCTGGCCGATATCGCCGGCAAGATCGCTG
GCGTCGGCATCACCCGCACCGCGCTGATCCTGGTTGGGCGCGGCCTGGGCAGCGAGGATTTCGCCAATAGCCGACTGTAT
GCCGCCGACTGCGGCCACGCCTTTCGGTCGGCCTCGGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGCCAAAACCCGCTCCCAGCGCGCCACCTGCGCGTTGGCCCGCACGCCGCTCGACGCCCCGTCTTTTTCGGGGACG
CCCGCCAAGGAGATGACCCC

Downstream 100 bases:

>100_bases
TCGATGCGCTACCGCCCTTTGGCGCTCTGGATCCGCGACGCCCGGCGCTCCAGTTAGGCGGCGGGGTGAGGTCGGCGGCC
AAGGGGCTTGGCCGTCTGGT

Product: precorrin-4 C11-methyltransferase

Products: NA

Alternate protein names: Precorrin-3 methylase [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTVHFIGAGPGAPDLITLRGLRLIQSCPVVLFAGSLIPREVVAEAGAEARVIDSSALHLDEIIAVMAEATARGEDIARLH
SGDPSLYGAIAEQIRRLRGLGIAYDICPGVPSYAAAAAALGNELTLPEVCQTVILTRTSVRASPMPAGEDLESLGRSGAL
LAIHLSIANLAEVEAKLTPLYGADCPVAVVYRASWPDQTVVRGTLADIAGKIAGVGITRTALILVGRGLGSEDFANSRLY
AADCGHAFRSASA

Sequences:

>Translated_253_residues
MTVHFIGAGPGAPDLITLRGLRLIQSCPVVLFAGSLIPREVVAEAGAEARVIDSSALHLDEIIAVMAEATARGEDIARLH
SGDPSLYGAIAEQIRRLRGLGIAYDICPGVPSYAAAAAALGNELTLPEVCQTVILTRTSVRASPMPAGEDLESLGRSGAL
LAIHLSIANLAEVEAKLTPLYGADCPVAVVYRASWPDQTVVRGTLADIAGKIAGVGITRTALILVGRGLGSEDFANSRLY
AADCGHAFRSASA
>Mature_252_residues
TVHFIGAGPGAPDLITLRGLRLIQSCPVVLFAGSLIPREVVAEAGAEARVIDSSALHLDEIIAVMAEATARGEDIARLHS
GDPSLYGAIAEQIRRLRGLGIAYDICPGVPSYAAAAAALGNELTLPEVCQTVILTRTSVRASPMPAGEDLESLGRSGALL
AIHLSIANLAEVEAKLTPLYGADCPVAVVYRASWPDQTVVRGTLADIAGKIAGVGITRTALILVGRGLGSEDFANSRLYA
ADCGHAFRSASA

Specific function: Catalyzes the methylation of C-11 in precorrin-4 to form precorrin-5 [H]

COG id: COG2875

COG function: function code H; Precorrin-4 methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789768, Length=243, Percent_Identity=28.8065843621399, Blast_Score=80, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6322922, Length=260, Percent_Identity=23.4615384615385, Blast_Score=66, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR014776
- InterPro:   IPR006362
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.133 [H]

Molecular weight: Translated: 26161; Mature: 26030

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVHFIGAGPGAPDLITLRGLRLIQSCPVVLFAGSLIPREVVAEAGAEARVIDSSALHLD
CEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEECCHHHHHH
EIIAVMAEATARGEDIARLHSGDPSLYGAIAEQIRRLRGLGIAYDICPGVPSYAAAAAAL
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
GNELTLPEVCQTVILTRTSVRASPMPAGEDLESLGRSGALLAIHLSIANLAEVEAKLTPL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCC
YGADCPVAVVYRASWPDQTVVRGTLADIAGKIAGVGITRTALILVGRGLGSEDFANSRLY
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHEEEHEEECCCCCCCCCCCEEE
AADCGHAFRSASA
EHHHHHHHHCCCC
>Mature Secondary Structure 
TVHFIGAGPGAPDLITLRGLRLIQSCPVVLFAGSLIPREVVAEAGAEARVIDSSALHLD
EEEEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCHHHHHHHCCCCEEEECCHHHHHH
EIIAVMAEATARGEDIARLHSGDPSLYGAIAEQIRRLRGLGIAYDICPGVPSYAAAAAAL
HHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHH
GNELTLPEVCQTVILTRTSVRASPMPAGEDLESLGRSGALLAIHLSIANLAEVEAKLTPL
CCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCEEEEEEEHHHHHHHHHHHCCC
YGADCPVAVVYRASWPDQTVVRGTLADIAGKIAGVGITRTALILVGRGLGSEDFANSRLY
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHEEEHEEECCCCCCCCCCCEEE
AADCGHAFRSASA
EHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]