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The map label for this gene is hldD [H]

Identifier: 83594608

GI number: 83594608

Start: 3776040

End: 3777023

Strand: Reverse

Name: hldD [H]

Synonym: Rru_A3278

Alternate gene names: 83594608

Gene position: 3777023-3776040 (Counterclockwise)

Preceding gene: 83594615

Following gene: 83594607

Centisome position: 86.77

GC content: 65.24

Gene sequence:

>984_bases
ATGATTATCGTTACCGGTGGCGCCGGGTTCATCGGCTCCAATATTCTGGCCGGGCTGGAAGAGCGCGGCCATGGCGACCT
CGTTCTGGTCGACCGCCTGCGCGATGGCGTCAAATGGCGCAATGTGGCCAAGCGCGATCTGGCCGATATCGTCGCTCCCG
AAGCCTTGCCCGCCTTTCTCGACGGCCATCGCGGCGAGGTTTCGGCGATCCTTCACATGGGGGCGATCTCGGCGACGACC
GAGCGCGACGCCGATCGCATCATTGAAAACAACTTCCGTCTGTCGCGCGATCTGTGGCTGTGGTGCGCGGCCAATGGCGC
GCGCTTCGTCTATGCCAGCAGCGCCGCCACCTATGGCGATGGCGCCCTCGGGTTCGATGACGATTTTTCCCCGGCCGCCC
TGGCCCGCCTGCGTCCGCTCAACGCCTATGGCTGGTCCAAGCATCTGTTCGACCGCAAGGTGCGTCATTGGGTCGACTCC
GGGCCGGTGCCGCCGCAATGGGCCGGGCTGAAGTTCTTCAACGTCTATGGGCCCAACGAAACCCATAAGGGGCCGCAAAG
CAGCGTCGTCAGCCAGATCCATCCGGTGGCCCGGCGCGGCGAGTCCTTCGCCCTGTTCAAATCCCATGACCCGCGCTACG
CCGATGGTGGCCAGTTGCGCGATTTCGTCTGGATCGGCGATGTCGTCGATATCGTCCTCTGGCTGCTTGAAACGCCCAAG
GTCAGCGGCCTGTTCAACGTGGGCACCGGCCGCGCCCGCAGCTTCGCCGATCTGGCCGCCGCCGTTTATCGCGCCCTGGG
CGCCGAGCCGGCGCTGACCTATCGCGACATGCCCGAGGCGCTGCGCGACAAATACCAGTATTTCACCCAGGCCGAGATGG
GCCGGCTGCGCGCGGCGGGCTATCCCGGGCAGGCCACGCCTTTGGAAGAGGGGGTGCGGCGCTATGTTCAGGACTATCTG
GAACAAGCCGATCCCTTCCGCTGA

Upstream 100 bases:

>100_bases
GGCCGTTCGCCGGGGTGGCGGCGGGCCGATGGCGGGGCTATAAGGCGTCGATCCCTGGTTTTTTTCCGATCCATCGCGTC
GAACGGAAGGCTTTCCCCCC

Downstream 100 bases:

>100_bases
GCCGGGGCCGGCGCGCGGAAAGGCCACGAGCGGTTTTCCGCGCGAGCGCTGCCCTATCTTATTGAATTCAGGGCAAAGTC
TTTGTGCCAAAGGGGGGGCT

Product: ADP-glyceromanno-heptose 6-epimerase

Products: NA

Alternate protein names: ADP-L-glycero-beta-D-manno-heptose-6-epimerase; ADP-glyceromanno-heptose 6-epimerase; ADP-hep 6-epimerase; AGME [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MIIVTGGAGFIGSNILAGLEERGHGDLVLVDRLRDGVKWRNVAKRDLADIVAPEALPAFLDGHRGEVSAILHMGAISATT
ERDADRIIENNFRLSRDLWLWCAANGARFVYASSAATYGDGALGFDDDFSPAALARLRPLNAYGWSKHLFDRKVRHWVDS
GPVPPQWAGLKFFNVYGPNETHKGPQSSVVSQIHPVARRGESFALFKSHDPRYADGGQLRDFVWIGDVVDIVLWLLETPK
VSGLFNVGTGRARSFADLAAAVYRALGAEPALTYRDMPEALRDKYQYFTQAEMGRLRAAGYPGQATPLEEGVRRYVQDYL
EQADPFR

Sequences:

>Translated_327_residues
MIIVTGGAGFIGSNILAGLEERGHGDLVLVDRLRDGVKWRNVAKRDLADIVAPEALPAFLDGHRGEVSAILHMGAISATT
ERDADRIIENNFRLSRDLWLWCAANGARFVYASSAATYGDGALGFDDDFSPAALARLRPLNAYGWSKHLFDRKVRHWVDS
GPVPPQWAGLKFFNVYGPNETHKGPQSSVVSQIHPVARRGESFALFKSHDPRYADGGQLRDFVWIGDVVDIVLWLLETPK
VSGLFNVGTGRARSFADLAAAVYRALGAEPALTYRDMPEALRDKYQYFTQAEMGRLRAAGYPGQATPLEEGVRRYVQDYL
EQADPFR
>Mature_327_residues
MIIVTGGAGFIGSNILAGLEERGHGDLVLVDRLRDGVKWRNVAKRDLADIVAPEALPAFLDGHRGEVSAILHMGAISATT
ERDADRIIENNFRLSRDLWLWCAANGARFVYASSAATYGDGALGFDDDFSPAALARLRPLNAYGWSKHLFDRKVRHWVDS
GPVPPQWAGLKFFNVYGPNETHKGPQSSVVSQIHPVARRGESFALFKSHDPRYADGGQLRDFVWIGDVVDIVLWLLETPK
VSGLFNVGTGRARSFADLAAAVYRALGAEPALTYRDMPEALRDKYQYFTQAEMGRLRAAGYPGQATPLEEGVRRYVQDYL
EQADPFR

Specific function: Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose [H]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family. HldD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790049, Length=318, Percent_Identity=43.0817610062893, Blast_Score=231, Evalue=5e-62,
Organism=Caenorhabditis elegans, GI115532424, Length=343, Percent_Identity=24.4897959183673, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR011912
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.20 [H]

Molecular weight: Translated: 36192; Mature: 36192

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIVTGGAGFIGSNILAGLEERGHGDLVLVDRLRDGVKWRNVAKRDLADIVAPEALPAFL
CEEEECCCCHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHHHCHHHHHHHH
DGHRGEVSAILHMGAISATTERDADRIIENNFRLSRDLWLWCAANGARFVYASSAATYGD
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEECCCCEEEEECCCCCCCC
GALGFDDDFSPAALARLRPLNAYGWSKHLFDRKVRHWVDSGPVPPQWAGLKFFNVYGPNE
CCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
THKGPQSSVVSQIHPVARRGESFALFKSHDPRYADGGQLRDFVWIGDVVDIVLWLLETPK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHEEHHHHHHHHHHHHCCCC
VSGLFNVGTGRARSFADLAAAVYRALGAEPALTYRDMPEALRDKYQYFTQAEMGRLRAAG
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPGQATPLEEGVRRYVQDYLEQADPFR
CCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIIVTGGAGFIGSNILAGLEERGHGDLVLVDRLRDGVKWRNVAKRDLADIVAPEALPAFL
CEEEECCCCHHHHHHHHHHHHCCCCCEEEEHHHHCCHHHHHHHHHHHHHHHCHHHHHHHH
DGHRGEVSAILHMGAISATTERDADRIIENNFRLSRDLWLWCAANGARFVYASSAATYGD
CCCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCEEEEEECCCCEEEEECCCCCCCC
GALGFDDDFSPAALARLRPLNAYGWSKHLFDRKVRHWVDSGPVPPQWAGLKFFNVYGPNE
CCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCC
THKGPQSSVVSQIHPVARRGESFALFKSHDPRYADGGQLRDFVWIGDVVDIVLWLLETPK
CCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHEEHHHHHHHHHHHHCCCC
VSGLFNVGTGRARSFADLAAAVYRALGAEPALTYRDMPEALRDKYQYFTQAEMGRLRAAG
CCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YPGQATPLEEGVRRYVQDYLEQADPFR
CCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA