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The map label for this gene is rnhB

Identifier: 83594539

GI number: 83594539

Start: 3699820

End: 3700476

Strand: Direct

Name: rnhB

Synonym: Rru_A3209

Alternate gene names: 83594539

Gene position: 3699820-3700476 (Clockwise)

Preceding gene: 83594535

Following gene: 83594540

Centisome position: 85.0

GC content: 71.99

Gene sequence:

>657_bases
ATGCCCGATCTTTCCCTGGAACGGGCCTGCGGCGGCCGGGTCGCCGGCGTTGACGAGGTGGGCCGGGGACCGCTGGCCGG
ACCGGTGGTCGCCGCCGCCGTCGTCATCGATGCCGGACGCGCCGATCCCGCCCTGCTCGCCCGCCTTGATGATTCCAAGA
AGCTGTCGGCCGCCCTGCGCCAACGGCTGGCTACGGCCCTGCTCGCCGATCCGGGGGTCGAGGTCGGCCTGGGCGAGGCC
AGCGTCGCCGAGATCGACCGGATCAATATCCTTCAGGCCACCTTCCTGGCGATGGGGCGGGCTTTGGCCAAACTGGCCCC
CCCCGTCGATCTGGCCCTGGTCGACGGCAACCGCCTGCCGCCCCTGCCCTGCCCCGGTCAGGCCGTGGTTCGCGGCGACG
GCCTGTCGCTGTCGATCGCGGCGGCCAGCATCGTCGCCAAGGTGCACCGCGACGCGGCCATGGCGACGCTGGCCCAGGCC
CTCCCCGGCTATGGCTGGGAACGCAACGCCGGCTATGGCACGGCCGAGCATCTGGCGGCCCTCGATCGCCTGGGAGCGAC
GCCCCATCACCGCGCCTCCTTCGCCCCGGTGCGCGAGGCCCTTGCCCGATCAGCGCTCCCGGGGCATAAGTGTGTAACGG
CCTTGACTTTTTCGTGA

Upstream 100 bases:

>100_bases
CCCCCCGGCCCTTGGACGGCCGGCGTTGACGGCGCCTTGGCAAGGGCTATGGTTGGCCCGGCCATTTCCGCTTTTTTCCC
AGTCGCAAAGGATTTCCGCC

Downstream 100 bases:

>100_bases
TGCCACTAACCTAGATCCGGTGGCCGAGTCGCAGCCGGACACCACATCCTGGGCTCCGGCCCTTTGGTTTGTCGTTTTCT
CGTGATCGGCTCGCAAGCAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MPDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALRQRLATALLADPGVEVGLGEA
SVAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLPPLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQA
LPGYGWERNAGYGTAEHLAALDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS

Sequences:

>Translated_218_residues
MPDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALRQRLATALLADPGVEVGLGEA
SVAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLPPLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQA
LPGYGWERNAGYGTAEHLAALDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS
>Mature_217_residues
PDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALRQRLATALLADPGVEVGLGEAS
VAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLPPLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQAL
PGYGWERNAGYGTAEHLAALDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=188, Percent_Identity=52.1276595744681, Blast_Score=164, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_RHORT (Q2RPE1)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_428291.1
- ProteinModelPortal:   Q2RPE1
- SMR:   Q2RPE1
- STRING:   Q2RPE1
- GeneID:   3836655
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A3209
- NMPDR:   fig|1085.1.peg.851
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q2RPE1
- ProtClustDB:   PRK00015
- BioCyc:   RRUB269796:RRU_A3209-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 22260; Mature: 22129

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALR
CCCCCCHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHH
QRLATALLADPGVEVGLGEASVAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLP
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
PLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQALPGYGWERNAGYGTAEHLAA
CCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECC
>Mature Secondary Structure 
PDLSLERACGGRVAGVDEVGRGPLAGPVVAAAVVIDAGRADPALLARLDDSKKLSAALR
CCCCCHHHCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHEECCCHHHHHHHHH
QRLATALLADPGVEVGLGEASVAEIDRINILQATFLAMGRALAKLAPPVDLALVDGNRLP
HHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCC
PLPCPGQAVVRGDGLSLSIAAASIVAKVHRDAAMATLAQALPGYGWERNAGYGTAEHLAA
CCCCCCCEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LDRLGATPHHRASFAPVREALARSALPGHKCVTALTFS
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA