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The map label for this gene is rnr [H]

Identifier: 83594533

GI number: 83594533

Start: 3692386

End: 3694914

Strand: Direct

Name: rnr [H]

Synonym: Rru_A3203

Alternate gene names: 83594533

Gene position: 3692386-3694914 (Clockwise)

Preceding gene: 83594532

Following gene: 83594534

Centisome position: 84.83

GC content: 69.79

Gene sequence:

>2529_bases
ATGCCATCGCTGGCTCCTCTCTGGCATGATGGCGCGGACCCCGGGAACGGGATCCGCGCCCGCCGCGTTTTTCCCCAAGA
CAGCCTTTGGCTTTCCCGGCCAAACCGGCGTTTTCCCGACCCTAAGGACAGCCCTTTGACCCCCAAGGCCCCCAAGCACG
TCCCCTTCCCCAGCCGCGAGCAGGTGCTGGAGTTCATCCGCGCCGCCAACGGCGAGGTCGACCGACGCGAGATCGCCAGG
GCCTTCCACATCACCGGACCAGAGCGCGCCGATCTGCGCACCCTGCTTAAGGAGTTGGAGAGCGAGGGCGCCCTGCAGCG
CGGCCGTGGCCGCCGCATCGCCCCGCCGGGCAGCCTGCCCGAGGTGGCGGTGCTGATCGTCGCCCGGGCGGACGCCGAGG
GGGATCTGTTCTGCAAGCCCGAGCATTGGCCAGAGGACGAGGAGCCGCCGCGCATCCTGCTGTGGCCCGAGCCCCATCAC
GCCCGGCGCCCGGGGGTCGGCGCCGAGATCGGCGTGGGCGACCGCATCCTCGCCCGCCTGACCCGCATCGGCGACGCGCG
TTATGACGCCCGCACGATCCGCCGGCTGGCGGCCGCCCCCTCGCGCCTGCTGGGCGTGCTGGCCCTGGCCCGCGACGGCC
TGCGCCTGCGCCCGACCAACCGCCGCGACCGCGACGAATATCTGGTCGCCCCCGAGGATGCCGGCGGGGCCGAACCCGGC
GAGTTGGTCGAGGCCGAACTGCTGCCCTCGCGCCGCCTTGGCCTGCGTCGGGCCAAGGTGATCGAGCGGCTGGGCGGCCG
CGAGGGGCCGCGCTCGATCAGTCTGGTCGTTGTCCATAGCCACGACATCCCCGTTGATTTCCCGCCCGAGGCCCTGGCCG
AAGCCGAGGCCGCCGTGGGCGTCGACCTGCGCGGCCGCGAAGACCTGCGCGCCGTGCCGCTGGTCACCATCGACGGCGAG
GACGCCCGCGACTTCGACGACGCGGTCTTCGCCGAACCCGATGACGACCCGGCCAATCCCGGCGGCTGGCGGGCGCTGGT
CGCCATCGCCGATGTCGCCCATTACGTTCGCATCGGCGCTGCCCTCGACAAGGCGGCGCGCGAGCGCGGCAATTCGGTTT
ATTTCCCCGACCGCGTCGTGCCGATGCTGCCCGAGGCGCTGTCGAACGGCTGGTGTTCCTTGCGCCCCAATGAGGATCGC
GGCTGCCTCGCGGTGTGGATGATCTTCGACGCCGAGGGCAACAAGCTGCGCCACCGCTTCCTGCGCGGCCTGATGCGCTC
GGCCGCCCGCCTGACCTATACCCAGGTTCAGGCCGCCCGCGACGGCCATGCCGACGATCTGACCGCGCCCTTGCAAGAGC
GTGTCATCGCCCCGCTCTACGGCGTTTTCCAAGCGCTTCTGGGCGCGCGCAGCCGGCGCGGCACGCTGGAACTCGACCTG
CCCGAACGCAAGGTGGTGCTTGATGACGGCGGCGAGGTGGCGCGCATCGAGCCGCGCCTGCGCTTTGACAGCCACAAGCT
GATCGAAGAACTGATGATCGCGGCCAATGTCAGCGCCGCCGAGACCCTGGAGGAAAAGCGCCGCCCCTGCATGTACCGCG
TCCACGACCAGCCGGCGCCCGATAAGCTGGTGGCTTTGGGCGAATTTCTCGAGTCGCTCGATATTCCCTTTCATAAGGGA
TCAATCAATCGGTCGGGCCAATTCAATGGCGTGCTGAAAGCCGCCCGCGGCACGCCCCACGAGCATATGGTCAATGAGGT
GGTTCTGCGCTCGCAAGCCCAGGCCGAATACAGCCCCGATAACATCGGTCATTTTGGCCTCGCCCTGCGCCGCTACGCCC
ATTTCACCTCGCCGATCCGCCGCTATGCCGACCTGTTGGTCCACCGCGCGCTGATCGCCGGCCTGGGCCTGGGCGACGAC
GGCCTGCGACCGGGCGCCGAAGAGGATTTCGTCGAGACCGCCGCCCATATCACCGCCACCGAGCGCCGCGCCGCCCAGGC
CGAACGCGACGCCGTCAACCGCTATACGGTCAGTTTCCTGGCCGCCAAGGTCGGGGCGACCTTCGCCGGCCGAATCAATG
GCGTCACCCGCGCCGGGTTGTTCGTCACCCTGGAGGACACCGGCGCCGACGGGCTGATCCCGATCGGCAGCCTGCCCAAC
GACTACTATGTCCATGATGATGCCCATCATTGTCTGCGCGGCCAGCGCGACGGCCTGGAATTCCACCTGGGGGCGCCGGT
CGAGGTTCTGCTGCGCGAGGCCAATCCGGTCAGCGGCGGGCTGGTCTTCGGCTTGCTTCAAGGCGGGGTCGCCGGCGCCG
CCAAGGGGCGGGGCTTCTCTGGAAAAACCAAAGGTCGCGACGGCCTTGGCAAGACCCGCTTGAAGGAGCGCGGCGCGGCG
GCGAAGCTCAAGAAAGGGGCGCGCGGCAAGCCCAAGGCGGCCGGGCGCGACGCCTTGGCCGGCGAGCCGGTCGGGAGCGG
CCCCAAGAAACGCCCGCCCACCACGACCTCCCGTCGTAAAACCCGTTGA

Upstream 100 bases:

>100_bases
TCGGCCGAAGACGCCCCGGCCAAGGCGCCGCGCAAGAGCAAGGCCAAACCGGCGAGCGCCGATCCGGACTGAAAGCGGCG
GCTTTTGCCCGCGAAGGGCG

Downstream 100 bases:

>100_bases
TACCACGTGTTTTTGAAAAGGAATATTTCCGAAAAAGCCCATAGACAGGGGAGCGCATCTTGCCTAACCCTGAAGGCAGG
ATGACAGCGTCGATCGCGGC

Product: RNAse R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MPSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSREQVLEFIRAANGEVDRREIAR
AFHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLPEVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHH
ARRPGVGAEIGVGDRILARLTRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPG
ELVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVGVDLRGREDLRAVPLVTIDGE
DARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGAALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDR
GCLAVWMIFDAEGNKLRHRFLRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDL
PERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAPDKLVALGEFLESLDIPFHKG
SINRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPDNIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDD
GLRPGAEEDFVETAAHITATERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPN
DYYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFSGKTKGRDGLGKTRLKERGAA
AKLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRKTR

Sequences:

>Translated_842_residues
MPSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSREQVLEFIRAANGEVDRREIAR
AFHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLPEVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHH
ARRPGVGAEIGVGDRILARLTRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPG
ELVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVGVDLRGREDLRAVPLVTIDGE
DARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGAALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDR
GCLAVWMIFDAEGNKLRHRFLRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDL
PERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAPDKLVALGEFLESLDIPFHKG
SINRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPDNIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDD
GLRPGAEEDFVETAAHITATERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPN
DYYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFSGKTKGRDGLGKTRLKERGAA
AKLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRKTR
>Mature_841_residues
PSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSREQVLEFIRAANGEVDRREIARA
FHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLPEVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHHA
RRPGVGAEIGVGDRILARLTRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPGE
LVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVGVDLRGREDLRAVPLVTIDGED
ARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGAALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDRG
CLAVWMIFDAEGNKLRHRFLRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDLP
ERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAPDKLVALGEFLESLDIPFHKGS
INRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPDNIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDDG
LRPGAEEDFVETAAHITATERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPND
YYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFSGKTKGRDGLGKTRLKERGAAA
KLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRKTR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=485, Percent_Identity=25.360824742268, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI190014623, Length=485, Percent_Identity=25.360824742268, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI134288890, Length=380, Percent_Identity=31.3157894736842, Blast_Score=154, Evalue=5e-37,
Organism=Homo sapiens, GI219521928, Length=491, Percent_Identity=28.1059063136456, Blast_Score=133, Evalue=9e-31,
Organism=Homo sapiens, GI19115966, Length=491, Percent_Identity=28.1059063136456, Blast_Score=132, Evalue=1e-30,
Organism=Escherichia coli, GI87082383, Length=731, Percent_Identity=35.9781121751026, Blast_Score=388, Evalue=1e-109,
Organism=Escherichia coli, GI1787542, Length=417, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI17553506, Length=461, Percent_Identity=27.5488069414317, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI212645896, Length=483, Percent_Identity=29.1925465838509, Blast_Score=150, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6324552, Length=440, Percent_Identity=29.3181818181818, Blast_Score=151, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24649634, Length=552, Percent_Identity=27.8985507246377, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24654592, Length=462, Percent_Identity=26.8398268398268, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19922976, Length=462, Percent_Identity=26.8398268398268, Blast_Score=136, Evalue=5e-32,
Organism=Drosophila melanogaster, GI24654597, Length=462, Percent_Identity=26.8398268398268, Blast_Score=136, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 92043; Mature: 91912

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSRE
CCCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QVLEFIRAANGEVDRREIARAFHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLP
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCC
EVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHHARRPGVGAEIGVGDRILARL
CEEEEEEEECCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
TRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPG
HHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCCH
ELVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVG
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHC
VDLRGREDLRAVPLVTIDGEDARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGA
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDRGCLAVWMIFDAEGNKLRHRF
HHHHHHHHCCCEEECCCCHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEECCCHHHHHHH
LRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
PERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAP
CCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCC
DKLVALGEFLESLDIPFHKGSINRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
NIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDDGLRPGAEEDFVETAAHITAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
ERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEEEECCCCCCEEECCCCCC
DYYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFS
CCEEECCHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
GKTKGRDGLGKTRLKERGAAAKLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRK
CCCCCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TR
CC
>Mature Secondary Structure 
PSLAPLWHDGADPGNGIRARRVFPQDSLWLSRPNRRFPDPKDSPLTPKAPKHVPFPSRE
CCCCCCCCCCCCCCCCCEEEEECCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCHH
QVLEFIRAANGEVDRREIARAFHITGPERADLRTLLKELESEGALQRGRGRRIAPPGSLP
HHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCC
EVAVLIVARADAEGDLFCKPEHWPEDEEPPRILLWPEPHHARRPGVGAEIGVGDRILARL
CEEEEEEEECCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHH
TRIGDARYDARTIRRLAAAPSRLLGVLALARDGLRLRPTNRRDRDEYLVAPEDAGGAEPG
HHHCCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCEECCCCCCCCCCEEECCCCCCCCCCH
ELVEAELLPSRRLGLRRAKVIERLGGREGPRSISLVVVHSHDIPVDFPPEALAEAEAAVG
HHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHC
VDLRGREDLRAVPLVTIDGEDARDFDDAVFAEPDDDPANPGGWRALVAIADVAHYVRIGA
CCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ALDKAARERGNSVYFPDRVVPMLPEALSNGWCSLRPNEDRGCLAVWMIFDAEGNKLRHRF
HHHHHHHHCCCEEECCCCHHHHHHHHHCCCEEECCCCCCCCEEEEEEEEECCCHHHHHHH
LRGLMRSAARLTYTQVQAARDGHADDLTAPLQERVIAPLYGVFQALLGARSRRGTLELDL
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
PERKVVLDDGGEVARIEPRLRFDSHKLIEELMIAANVSAAETLEEKRRPCMYRVHDQPAP
CCCEEEEECCCCEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCC
DKLVALGEFLESLDIPFHKGSINRSGQFNGVLKAARGTPHEHMVNEVVLRSQAQAEYSPD
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
NIGHFGLALRRYAHFTSPIRRYADLLVHRALIAGLGLGDDGLRPGAEEDFVETAAHITAT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
ERRAAQAERDAVNRYTVSFLAAKVGATFAGRINGVTRAGLFVTLEDTGADGLIPIGSLPN
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCEEECCEEEEEECCCCCCEEECCCCCC
DYYVHDDAHHCLRGQRDGLEFHLGAPVEVLLREANPVSGGLVFGLLQGGVAGAAKGRGFS
CCEEECCHHHHHCCCCCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
GKTKGRDGLGKTRLKERGAAAKLKKGARGKPKAAGRDALAGEPVGSGPKKRPPTTTSRRK
CCCCCCCCCCHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]