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The map label for this gene is etfA [H]

Identifier: 83594408

GI number: 83594408

Start: 3543846

End: 3544781

Strand: Direct

Name: etfA [H]

Synonym: Rru_A3078

Alternate gene names: 83594408

Gene position: 3543846-3544781 (Clockwise)

Preceding gene: 83594407

Following gene: 83594409

Centisome position: 81.41

GC content: 67.41

Gene sequence:

>936_bases
ATGGCTTTGCTGGTAATCGCCGAACACGACAACGCGTCGCTCAAGCCCGCCACCCTCAATACGGTGGCCGCCGCCGCCCA
GTTGGGTGGTGACATTCACGTTCTGGTCGCCGGCCAGACCTGCGCCGCCGCCGCCGAGGCCGCCGCCAAGGTGGCCGGGG
TAACCAAGGTCTTGGTCGCCGACGACGCGGTCTATGCCCATCCCTTGGCCGAAAGCCTGACCCCGCTGATCGTGTCGCTG
GCCAGGGAGTATTCCCACGTCCTCGCCCCGGCGACGACGACGGGCAAGAACATCCTGCCGCGAGTCGCCGCCCTTCTCGA
TGTCGCCCAGGTTTCCGACATCACCGCCGTGATCGCCGAGGATACCTTCGTGCGGCCGATCTACGCCGGCAACGCCCTGG
CCACCGTGCGCAGCGCCGACAGCCCCAAGGTCATCACCGTCCGCACCACCGCCTTCGATCCGGCCAACGCCGACGGCGGC
CAGGGGGTGGTTGAAAGCATCTCGGCCACCGCCAGCTCCGGCCTGTCGAGCTTCGTCGGCCAGGAACTGTCGAAATCGGC
CCGCCCCGAGCTGACCAGCGCCCGCGTCATCATTTCCGGCGGCCGTGGCATGGGGTCGGGGGAGAACTTCGCCCTGATCG
AAGCCCTGGCCGACAAGCTGGGCGCCGCCGTCGGCGCCAGCCGCGCCGCCGTCGATGCCGGCTATGTGCCCAACGACTAT
CAGGTCGGCCAGACCGGCAAGATCGTCGCCCCGGATCTTTATGTCGCCGTGGGGATCTCGGGCGCCATCCAGCATCTGGC
GGGCATGAAGGACAGCAAGGTCATCGTCGCCATCAACAAGGACGAGGAAGCTCCCATCTTCCAGGTCGCCGACTACGGGC
TGGTCGCCGACCTGTTTCAGGCCGTGCCCGCGCTGACCGCCGCATTAGACAAATAA

Upstream 100 bases:

>100_bases
CTGAAGGTGGAAGAGCCCGCCAGCCGCAAGGCCGGCGTCCGCGTGCCCGACGTGGCCACATTGGTCGAAAAGCTCAAGAC
CGAGGCGAAGGTGATCTGAC

Downstream 100 bases:

>100_bases
TCCCGGGGGACGATCCGTCCCCGCAAGCGGAAAGGCTCCAAGATGGTCGAAAAGATTGGCGTGATCGGCGCTGGCCAGAT
GGGCAATGGTATCGCCCATA

Product: electron transfer flavoprotein

Products: NA

Alternate protein names: Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS [H]

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MALLVIAEHDNASLKPATLNTVAAAAQLGGDIHVLVAGQTCAAAAEAAAKVAGVTKVLVADDAVYAHPLAESLTPLIVSL
AREYSHVLAPATTTGKNILPRVAALLDVAQVSDITAVIAEDTFVRPIYAGNALATVRSADSPKVITVRTTAFDPANADGG
QGVVESISATASSGLSSFVGQELSKSARPELTSARVIISGGRGMGSGENFALIEALADKLGAAVGASRAAVDAGYVPNDY
QVGQTGKIVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFQAVPALTAALDK

Sequences:

>Translated_311_residues
MALLVIAEHDNASLKPATLNTVAAAAQLGGDIHVLVAGQTCAAAAEAAAKVAGVTKVLVADDAVYAHPLAESLTPLIVSL
AREYSHVLAPATTTGKNILPRVAALLDVAQVSDITAVIAEDTFVRPIYAGNALATVRSADSPKVITVRTTAFDPANADGG
QGVVESISATASSGLSSFVGQELSKSARPELTSARVIISGGRGMGSGENFALIEALADKLGAAVGASRAAVDAGYVPNDY
QVGQTGKIVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFQAVPALTAALDK
>Mature_310_residues
ALLVIAEHDNASLKPATLNTVAAAAQLGGDIHVLVAGQTCAAAAEAAAKVAGVTKVLVADDAVYAHPLAESLTPLIVSLA
REYSHVLAPATTTGKNILPRVAALLDVAQVSDITAVIAEDTFVRPIYAGNALATVRSADSPKVITVRTTAFDPANADGGQ
GVVESISATASSGLSSFVGQELSKSARPELTSARVIISGGRGMGSGENFALIEALADKLGAAVGASRAAVDAGYVPNDYQ
VGQTGKIVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFQAVPALTAALDK

Specific function: The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI4503607, Length=310, Percent_Identity=62.258064516129, Blast_Score=376, Evalue=1e-104,
Organism=Homo sapiens, GI189181759, Length=276, Percent_Identity=62.3188405797101, Blast_Score=333, Evalue=1e-91,
Organism=Escherichia coli, GI1786226, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1787990, Length=261, Percent_Identity=32.183908045977, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082157, Length=221, Percent_Identity=34.3891402714932, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17506929, Length=309, Percent_Identity=58.8996763754045, Blast_Score=352, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6325261, Length=297, Percent_Identity=44.1077441077441, Blast_Score=249, Evalue=6e-67,
Organism=Drosophila melanogaster, GI17136898, Length=309, Percent_Identity=64.7249190938511, Blast_Score=389, Evalue=1e-108,
Organism=Drosophila melanogaster, GI24652801, Length=309, Percent_Identity=64.7249190938511, Blast_Score=389, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 31448; Mature: 31317

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS ; PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALLVIAEHDNASLKPATLNTVAAAAQLGGDIHVLVAGQTCAAAAEAAAKVAGVTKVLVA
CEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
DDAVYAHPLAESLTPLIVSLAREYSHVLAPATTTGKNILPRVAALLDVAQVSDITAVIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEC
DTFVRPIYAGNALATVRSADSPKVITVRTTAFDPANADGGQGVVESISATASSGLSSFVG
CCEECEEECCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QELSKSARPELTSARVIISGGRGMGSGENFALIEALADKLGAAVGASRAAVDAGYVPNDY
HHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKIVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFQ
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
AVPALTAALDK
HHHHHHHHHCC
>Mature Secondary Structure 
ALLVIAEHDNASLKPATLNTVAAAAQLGGDIHVLVAGQTCAAAAEAAAKVAGVTKVLVA
EEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHEEEEEE
DDAVYAHPLAESLTPLIVSLAREYSHVLAPATTTGKNILPRVAALLDVAQVSDITAVIAE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEC
DTFVRPIYAGNALATVRSADSPKVITVRTTAFDPANADGGQGVVESISATASSGLSSFVG
CCEECEEECCCCEEEEECCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHH
QELSKSARPELTSARVIISGGRGMGSGENFALIEALADKLGAAVGASRAAVDAGYVPNDY
HHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
QVGQTGKIVAPDLYVAVGISGAIQHLAGMKDSKVIVAINKDEEAPIFQVADYGLVADLFQ
EECCCCCEECCCEEEEECHHHHHHHHHCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHH
AVPALTAALDK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]