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The map label for this gene is glmU [H]

Identifier: 83594360

GI number: 83594360

Start: 3488824

End: 3490254

Strand: Reverse

Name: glmU [H]

Synonym: Rru_A3030

Alternate gene names: 83594360

Gene position: 3490254-3488824 (Counterclockwise)

Preceding gene: 83594370

Following gene: 83594359

Centisome position: 80.18

GC content: 69.11

Gene sequence:

>1431_bases
GTGATCGCCGCCGTTCCCCCGCCCATCGTCGCCGCGCCTGCGCTTCCTGCCGCAGACCCGGATCCCGCAACAATAACCGC
TGGTTTTCCGATGACCAAGACCGCAGCCGTCATTCTCGCCGCCGGACAGGGCACGCGGATGAAATCCGCGCTTCCCAAGG
TTCTCCACCCGCTGGCCGGCCGGCCGATGGTCGCCCATCTGATCCACGCCCTGGGAGCGGTGGCGCCCAGCCGCACGGTG
GTGGTTATCGGCCCGGGGATGGAAAGCGTGGCCGATCGCGTCGCCCCGCTGCCCACCGTGCTGCAGGCCGAGCGCCTGGG
CACCGCCCATGCGGTGGCCCAGGCCGGGGAAGCCTTGGCCGGTTTTGACGGCACCGTGCTGATCCTGTATGGCGATACGC
CGCTGATCACCCCGGAAACCCTGACCCGCATGGTCGAGGCCCGGCTGGCCGCCGAGGATCCGGCGGTGGTGGTCCTAGGC
TTCCGTCCGGCCGATCCCTTGCAGTATGGCCGGCTGATCACCAGCCCGGCCGGCTTGGAGGCGATCGTTGAATACAAGGA
CGCCACGGCCGAGCAGCGGGCGATCGGCCTGTGCAATTCCGGGGTGATGGCGGTCGATGGCCGGGTGTTGTTCGCCCTGC
TCGCGGCGGTGGGCAACGACAACGCCAAGGGTGAATACTACCTGACCGATATCGTCGCCCTCGCCCGGGGGATGGGCCGC
GCCTGCGCCGTGGTCGAAGGTGCGGCCGAGGAACTGCTGGGCGTCAACAGCCGGTCGGAGCTGGCCGCCGCCGAGGCGGT
GATCCAGGGCCGGCTGCGCGAGAAGGCGATGGAGGGCGGGGCGACCCTGACCGCGCCCGAAACCGTGTTCTTCAGCGCCG
ATACCCGCCTGGGCCGCGATGTCAGCATCGGCCCCTTCGTCACCTTCGGCCCGGGCGTCGAGATCGGCGATGGCGTCGAG
ATCAAGGGCTTTTGCCATATCGAAGGGGCACGGGTGGCGGCAAAGGCGACGCTGGGCCCCTATGCCCGCCTGCGGCCCGG
CGCGACGATCGCCGAGGGCGCCCATGTCGGCAATTTCGTTGAGATCAAGAACAGCGCCGTCGAACAGGGCGCCAAGGTCA
ATCACCTGACCTATATCGGCGATGCCCGGGTGGGGGCGCGGGCCAATATCGGCGCCGGCACCATCACCTGCAATTACGAC
GGCTTTGGCAAATACCATACCGACATCGGCGAAGGCGCCTTCATCGGTTCGAACACCGCCCTGGTGGCGCCGGTGAGCAT
CGGCGCCGGGGCGATCATCGGCGCCGGATCGACCATCGCCCGCGATGTCGAGGCCGACGCCCTGGCCCTGACCCGGGGCC
CCCACGAGGTCCGTCCCGGCTGGGCGGCCAAGTTCCGCGCGCATATGCGCCGGCTGACCGGCAAAAATTAG

Upstream 100 bases:

>100_bases
TGTAACGGACCGTAATAAAGTTTGATTTTGTGCGCTGCCGAAGCCTGTGGCACCTTGCGGCCACGAAGGATGGGGCGCCT
CCGGGCCGGGAGGGGGTCTG

Downstream 100 bases:

>100_bases
CTCGCGGGGGTTCCCCGGCGGTATTTCGTGTTTTCTAAGGAGTGGCTCCACCCATGTGCGGCATCATCGGCATTATCGGC
GTCAAGGACGTGGTTCCCTC

Product: glucosamine-1-phosphate N-acetyltransferase / UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MIAAVPPPIVAAPALPAADPDPATITAGFPMTKTAAVILAAGQGTRMKSALPKVLHPLAGRPMVAHLIHALGAVAPSRTV
VVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALAGFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLG
FRPADPLQYGRLITSPAGLEAIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGR
ACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRDVSIGPFVTFGPGVEIGDGVE
IKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFVEIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYD
GFGKYHTDIGEGAFIGSNTALVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN

Sequences:

>Translated_476_residues
MIAAVPPPIVAAPALPAADPDPATITAGFPMTKTAAVILAAGQGTRMKSALPKVLHPLAGRPMVAHLIHALGAVAPSRTV
VVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALAGFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLG
FRPADPLQYGRLITSPAGLEAIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGR
ACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRDVSIGPFVTFGPGVEIGDGVE
IKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFVEIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYD
GFGKYHTDIGEGAFIGSNTALVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN
>Mature_476_residues
MIAAVPPPIVAAPALPAADPDPATITAGFPMTKTAAVILAAGQGTRMKSALPKVLHPLAGRPMVAHLIHALGAVAPSRTV
VVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALAGFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLG
FRPADPLQYGRLITSPAGLEAIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGR
ACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRDVSIGPFVTFGPGVEIGDGVE
IKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFVEIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYD
GFGKYHTDIGEGAFIGSNTALVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=447, Percent_Identity=44.9664429530201, Blast_Score=341, Evalue=5e-95,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR018357
- InterPro:   IPR001228
- InterPro:   IPR011004 [H]

Pfam domain/function: PF01128 IspD [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 48796; Mature: 48796

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAAVPPPIVAAPALPAADPDPATITAGFPMTKTAAVILAAGQGTRMKSALPKVLHPLAG
CCCCCCCCCEECCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
RPMVAHLIHALGAVAPSRTVVVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALA
CHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCHHC
GFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLGFRPADPLQYGRLITSPAGLE
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCEECCCCCHH
AIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGR
HHHHHHHCCHHHHHHEECCCCEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
ACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCC
VSIGPFVTFGPGVEIGDGVEIKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFV
CCCCCEEEECCCCCCCCCEEEEEEEEECCCEEEEECCCCCHHHCCCCCCEECCCCCCCEE
EIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYDGFGKYHTDIGEGAFIGSNTA
EECCHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCE
LVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN
EEEEEECCCCEEEECCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIAAVPPPIVAAPALPAADPDPATITAGFPMTKTAAVILAAGQGTRMKSALPKVLHPLAG
CCCCCCCCCEECCCCCCCCCCCCEEEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCC
RPMVAHLIHALGAVAPSRTVVVIGPGMESVADRVAPLPTVLQAERLGTAHAVAQAGEALA
CHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCHHHHHHHHCCHHHHHHHHCCHHC
GFDGTVLILYGDTPLITPETLTRMVEARLAAEDPAVVVLGFRPADPLQYGRLITSPAGLE
CCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHCCEECCCCCHH
AIVEYKDATAEQRAIGLCNSGVMAVDGRVLFALLAAVGNDNAKGEYYLTDIVALARGMGR
HHHHHHHCCHHHHHHEECCCCEEEECHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCC
ACAVVEGAAEELLGVNSRSELAAAEAVIQGRLREKAMEGGATLTAPETVFFSADTRLGRD
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEEECCCCCCCC
VSIGPFVTFGPGVEIGDGVEIKGFCHIEGARVAAKATLGPYARLRPGATIAEGAHVGNFV
CCCCCEEEECCCCCCCCCEEEEEEEEECCCEEEEECCCCCHHHCCCCCCEECCCCCCCEE
EIKNSAVEQGAKVNHLTYIGDARVGARANIGAGTITCNYDGFGKYHTDIGEGAFIGSNTA
EECCHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCEEECCCCE
LVAPVSIGAGAIIGAGSTIARDVEADALALTRGPHEVRPGWAAKFRAHMRRLTGKN
EEEEEECCCCEEEECCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA