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The map label for this gene is dgdA [H]

Identifier: 83594339

GI number: 83594339

Start: 3466179

End: 3467510

Strand: Direct

Name: dgdA [H]

Synonym: Rru_A3009

Alternate gene names: 83594339

Gene position: 3466179-3467510 (Clockwise)

Preceding gene: 83594337

Following gene: 83594341

Centisome position: 79.63

GC content: 67.57

Gene sequence:

>1332_bases
ATGAAACAGATCCTGGCGCTCAATGCCTTCGACATGAGCGACGCCCCCACCCTGAGCGACAGCGCTCAACGGTTGCTGGC
CAAGCGCAAGGCCCTGTTCGGCGCCGCATCGGTGTTGTTCTACGATAAGCCGCTGGAACTGGTGCGGGCCGAGGGCTGCT
GGCTTTTTGACGAGGCCGGCGAGCGCTATCTCGATGTTTACAACAACGTGCCCTCGGTCGGGCATTGCCACCCCCATGTG
GTGGCGGCGGTCGCCGACCAGTTGGCCAAGATCAACACCCATACCCGCTATCTGAACGAGGCCATCCATCGCTACGCCGA
GCGGCTGGTCGCCACGCTGCCGCCCAGCCTGTCGAATATCACCTTCACCTGCACCGGCAGCGAGAGCAACGATCTGGCCC
TGCGTCTGGCCAGCCACTACAGCGGCGGCCGGGGGGTGATCGTCACCGAGACCGCCTATCACGGCAATACGGCGGCGGTG
ACCGAGGTTTCGCCCAGTTCGGCCCGCGATCACGCCCTCGCCCCCCATGTCCGCGTGGTCCGCGCCCCCGATTCCTACCG
CGTCGCCCCCGAGGCCCTGGCCGCCCGCTTCGCCGGCGATGTCGCCGCCGCTATCGCCGATCTGGCCGATCACGGCATCA
CATTGTCGGCGCTGCTCGTCGATTCGATCTTTTCCAGCGATGGCGTCTACGCCGATCCCGCCGGTTTCCTGGCCGAGGCC
GTCGCCGTCGTCCACCGCCACGGCGGCCTGTTCATCGCCGATGAGGTTCAGCCCGGCTTCGGGCGCACCGGCAGCGCCCT
GTGGGGGTTCCAGCGCCATGGCGTCACGCCCGATATCGTCACCATGGGCAAGCCGATGGGCAATGGCCTGCCAATGGGCG
GGGTGGCGACCCGGCCCGAGATCCTCGACGCCTTCTGCGCCGAGGTCGGCTATTTCAACACCTTCGGCGGCTCTCCGGCC
GCCGGCGCCGCCGGTTCGGCCGTCCTTGACGTCATCGAGGGCGAGGGGCTGATGGCCAATGCCGAGGCCGTCGGCGCTTA
CCTGCGCGAGAGCCTGGGCGCCCTGGCCAAACGCTTCCCGGTGATCGGCGATGTGCGCGGCGCCGGTTTGTTCGACGCCG
TCGAACTGGTCAGCGATCCCGAGGCCAAAACCCCCAGCCCCGAACTGGCCAGCGCCATCATCAACGGCCTGCGCCAGCGT
CATGTGCTGATCGGCGCCGCCGGTCCCTTCGGCAATATCCTGAAAGTCCGCCCGCCGCTGTGCTTCACCCGCGATCAGGT
CGATATCCTGGGCGCGGCGCTCGAAGAGGTATTGACCGAGATCGCGCCCTGA

Upstream 100 bases:

>100_bases
ACAAAGGCGCGATCCTCGCGTTTTTGTTCCATGCCTTAGAAACGCGGCGCCGCGGCTCGTCCGCCGCCCGCGACGGCCGC
AAAGCGGGAATGGGAAAGCC

Downstream 100 bases:

>100_bases
GCCCGGCCGCTCAGGGAACGATGACCTCGACCCCGGCGCGCTCGAGGATCAACCGCAGAGCGCCTTCGGGCCGCTGATCG
GTGACCAAGCGGCTGATCAC

Product: aminotransferase

Products: NA

Alternate protein names: DGD [H]

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKQILALNAFDMSDAPTLSDSAQRLLAKRKALFGAASVLFYDKPLELVRAEGCWLFDEAGERYLDVYNNVPSVGHCHPHV
VAAVADQLAKINTHTRYLNEAIHRYAERLVATLPPSLSNITFTCTGSESNDLALRLASHYSGGRGVIVTETAYHGNTAAV
TEVSPSSARDHALAPHVRVVRAPDSYRVAPEALAARFAGDVAAAIADLADHGITLSALLVDSIFSSDGVYADPAGFLAEA
VAVVHRHGGLFIADEVQPGFGRTGSALWGFQRHGVTPDIVTMGKPMGNGLPMGGVATRPEILDAFCAEVGYFNTFGGSPA
AGAAGSAVLDVIEGEGLMANAEAVGAYLRESLGALAKRFPVIGDVRGAGLFDAVELVSDPEAKTPSPELASAIINGLRQR
HVLIGAAGPFGNILKVRPPLCFTRDQVDILGAALEEVLTEIAP

Sequences:

>Translated_443_residues
MKQILALNAFDMSDAPTLSDSAQRLLAKRKALFGAASVLFYDKPLELVRAEGCWLFDEAGERYLDVYNNVPSVGHCHPHV
VAAVADQLAKINTHTRYLNEAIHRYAERLVATLPPSLSNITFTCTGSESNDLALRLASHYSGGRGVIVTETAYHGNTAAV
TEVSPSSARDHALAPHVRVVRAPDSYRVAPEALAARFAGDVAAAIADLADHGITLSALLVDSIFSSDGVYADPAGFLAEA
VAVVHRHGGLFIADEVQPGFGRTGSALWGFQRHGVTPDIVTMGKPMGNGLPMGGVATRPEILDAFCAEVGYFNTFGGSPA
AGAAGSAVLDVIEGEGLMANAEAVGAYLRESLGALAKRFPVIGDVRGAGLFDAVELVSDPEAKTPSPELASAIINGLRQR
HVLIGAAGPFGNILKVRPPLCFTRDQVDILGAALEEVLTEIAP
>Mature_443_residues
MKQILALNAFDMSDAPTLSDSAQRLLAKRKALFGAASVLFYDKPLELVRAEGCWLFDEAGERYLDVYNNVPSVGHCHPHV
VAAVADQLAKINTHTRYLNEAIHRYAERLVATLPPSLSNITFTCTGSESNDLALRLASHYSGGRGVIVTETAYHGNTAAV
TEVSPSSARDHALAPHVRVVRAPDSYRVAPEALAARFAGDVAAAIADLADHGITLSALLVDSIFSSDGVYADPAGFLAEA
VAVVHRHGGLFIADEVQPGFGRTGSALWGFQRHGVTPDIVTMGKPMGNGLPMGGVATRPEILDAFCAEVGYFNTFGGSPA
AGAAGSAVLDVIEGEGLMANAEAVGAYLRESLGALAKRFPVIGDVRGAGLFDAVELVSDPEAKTPSPELASAIINGLRQR
HVLIGAAGPFGNILKVRPPLCFTRDQVDILGAALEEVLTEIAP

Specific function: The dialkylglycine decarboxylase is of interest because it normally catalyzes both decarboxylation and amino transfer. It may be more properly described as a decarboxylating aminotransferase rather than an aminotransferring decarboxylase [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI37574042, Length=430, Percent_Identity=43.4883720930233, Blast_Score=350, Evalue=2e-96,
Organism=Homo sapiens, GI24119277, Length=426, Percent_Identity=41.3145539906103, Blast_Score=328, Evalue=5e-90,
Organism=Homo sapiens, GI226442705, Length=430, Percent_Identity=42.093023255814, Blast_Score=327, Evalue=2e-89,
Organism=Homo sapiens, GI226442709, Length=377, Percent_Identity=43.5013262599469, Blast_Score=308, Evalue=8e-84,
Organism=Homo sapiens, GI13994255, Length=450, Percent_Identity=35.7777777777778, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI4557809, Length=413, Percent_Identity=27.1186440677966, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI188536080, Length=465, Percent_Identity=24.0860215053763, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679950, Length=465, Percent_Identity=24.0860215053763, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38679946, Length=465, Percent_Identity=24.0860215053763, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI284507298, Length=216, Percent_Identity=32.4074074074074, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.1658291457286, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI145693181, Length=396, Percent_Identity=28.7878787878788, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1788044, Length=416, Percent_Identity=29.5673076923077, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1787560, Length=406, Percent_Identity=30.5418719211823, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1789759, Length=392, Percent_Identity=27.2959183673469, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1786991, Length=419, Percent_Identity=25.7756563245823, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786349, Length=322, Percent_Identity=27.9503105590062, Blast_Score=85, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=39.5454545454545, Blast_Score=315, Evalue=3e-86,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=37.3853211009174, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI25144271, Length=437, Percent_Identity=26.5446224256293, Blast_Score=124, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71992985, Length=135, Percent_Identity=40, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI25144274, Length=231, Percent_Identity=29.4372294372294, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541228, Length=454, Percent_Identity=24.4493392070485, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=404, Percent_Identity=26.7326732673267, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324432, Length=397, Percent_Identity=24.4332493702771, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356575, Length=434, Percent_Identity=41.705069124424, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI28574759, Length=453, Percent_Identity=37.7483443708609, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI161085790, Length=447, Percent_Identity=37.8076062639821, Blast_Score=281, Evalue=5e-76,
Organism=Drosophila melanogaster, GI21357415, Length=429, Percent_Identity=27.5058275058275, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI281366494, Length=448, Percent_Identity=23.8839285714286, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667139, Length=448, Percent_Identity=23.8839285714286, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24667143, Length=448, Percent_Identity=23.8839285714286, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =4.1.1.64 [H]

Molecular weight: Translated: 46524; Mature: 46524

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQILALNAFDMSDAPTLSDSAQRLLAKRKALFGAASVLFYDKPLELVRAEGCWLFDEAG
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCEEEHHHC
ERYLDVYNNVPSVGHCHPHVVAAVADQLAKINTHTRYLNEAIHRYAERLVATLPPSLSNI
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
TFTCTGSESNDLALRLASHYSGGRGVIVTETAYHGNTAAVTEVSPSSARDHALAPHVRVV
EEEEECCCCCCEEEEEECCCCCCCEEEEEECEECCCCEEEEECCCCCCCCCCCCCCEEEE
RAPDSYRVAPEALAARFAGDVAAAIADLADHGITLSALLVDSIFSSDGVYADPAGFLAEA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VAVVHRHGGLFIADEVQPGFGRTGSALWGFQRHGVTPDIVTMGKPMGNGLPMGGVATRPE
HHHHHHCCCEEEECCCCCCCCCCCCHHHCHHHCCCCCCHHCCCCCCCCCCCCCCCCCCHH
ILDAFCAEVGYFNTFGGSPAAGAAGSAVLDVIEGEGLMANAEAVGAYLRESLGALAKRFP
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHCC
VIGDVRGAGLFDAVELVSDPEAKTPSPELASAIINGLRQRHVLIGAAGPFGNILKVRPPL
CEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCEEEECCCC
CFTRDQVDILGAALEEVLTEIAP
EECCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKQILALNAFDMSDAPTLSDSAQRLLAKRKALFGAASVLFYDKPLELVRAEGCWLFDEAG
CCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHCCCCEEEHHHC
ERYLDVYNNVPSVGHCHPHVVAAVADQLAKINTHTRYLNEAIHRYAERLVATLPPSLSNI
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
TFTCTGSESNDLALRLASHYSGGRGVIVTETAYHGNTAAVTEVSPSSARDHALAPHVRVV
EEEEECCCCCCEEEEEECCCCCCCEEEEEECEECCCCEEEEECCCCCCCCCCCCCCEEEE
RAPDSYRVAPEALAARFAGDVAAAIADLADHGITLSALLVDSIFSSDGVYADPAGFLAEA
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHHHH
VAVVHRHGGLFIADEVQPGFGRTGSALWGFQRHGVTPDIVTMGKPMGNGLPMGGVATRPE
HHHHHHCCCEEEECCCCCCCCCCCCHHHCHHHCCCCCCHHCCCCCCCCCCCCCCCCCCHH
ILDAFCAEVGYFNTFGGSPAAGAAGSAVLDVIEGEGLMANAEAVGAYLRESLGALAKRFP
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCCCCCEECHHHHHHHHHHHHHHHHHHCC
VIGDVRGAGLFDAVELVSDPEAKTPSPELASAIINGLRQRHVLIGAAGPFGNILKVRPPL
CEECCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCEEEEECCCCCCCEEEECCCC
CFTRDQVDILGAALEEVLTEIAP
EECCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2180928; 8342040; 7947767; 7799433; 10556038 [H]