Click here to switch to the map view.

The map label for this gene is lspA [H]

Identifier: 83594297

GI number: 83594297

Start: 3418623

End: 3419105

Strand: Direct

Name: lspA [H]

Synonym: Rru_A2967

Alternate gene names: 83594297

Gene position: 3418623-3419105 (Clockwise)

Preceding gene: 83594296

Following gene: 83594298

Centisome position: 78.54

GC content: 64.8

Gene sequence:

>483_bases
ATGGCCCCGGCCCTGTCGCTCGCCGCCCTGGTCATCGCCCTGGATCAGGCCACCAAATGGGCGATCCTGACCTGGGTGAT
GGACCCGCCCCGGGTCATCGATGTCACCGGATTTTTCAATCTGGTGCTGGTGTGGAATCGCGGCATCAGCTTCGGGGTGA
TGAACAACCACGGCGAATGGAATGCCGCGATCTTGTCGGCGCTGGCCCTGGTCATCGCCGGCAGCCTGACTTGGTGGCTG
CGGCGGGCGGAAACCCGCTGGCAGCGGCTGGCCCTGCCGCTGATCATCGGCGGCGCCATCGGCAATGTCATCGACCGGCT
GATCCACGGGGCGGTGGTCGATTTCGTCGATCTCAGCATCGCCGGATATCATTGGCCGGCCTTCAATGTCGCCGATGCGG
CGATCACCGTCGGTGCTATTCTCCTGCTGATCGATACGCTGGTCCATCGCCCGCCGGTGGGCACGGATAAGGCCGGGGGT
TGA

Upstream 100 bases:

>100_bases
CGGTGCTGGGAGATCCTGCCCGATGTCGGCACCCACGCCCACGAGGGCCTGTGCGGGCGCTGCGACGAGGTCGTTTCCTC
GCTGACGGCGGGCTGAGCCC

Downstream 100 bases:

>100_bases
GCCCGGTCATCAAGGCGAGTAACAAGAACCCGTCCTTTCTCGGAATCAGGCAAGCAGGTCCGTCATGAACCCCTTCGCAC
GCACTCTTGTGGCCGCCGCC

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 160; Mature: 159

Protein sequence:

>160_residues
MAPALSLAALVIALDQATKWAILTWVMDPPRVIDVTGFFNLVLVWNRGISFGVMNNHGEWNAAILSALALVIAGSLTWWL
RRAETRWQRLALPLIIGGAIGNVIDRLIHGAVVDFVDLSIAGYHWPAFNVADAAITVGAILLLIDTLVHRPPVGTDKAGG

Sequences:

>Translated_160_residues
MAPALSLAALVIALDQATKWAILTWVMDPPRVIDVTGFFNLVLVWNRGISFGVMNNHGEWNAAILSALALVIAGSLTWWL
RRAETRWQRLALPLIIGGAIGNVIDRLIHGAVVDFVDLSIAGYHWPAFNVADAAITVGAILLLIDTLVHRPPVGTDKAGG
>Mature_159_residues
APALSLAALVIALDQATKWAILTWVMDPPRVIDVTGFFNLVLVWNRGISFGVMNNHGEWNAAILSALALVIAGSLTWWLR
RAETRWQRLALPLIIGGAIGNVIDRLIHGAVVDFVDLSIAGYHWPAFNVADAAITVGAILLLIDTLVHRPPVGTDKAGG

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=108, Percent_Identity=37.037037037037, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17221; Mature: 17090

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPALSLAALVIALDQATKWAILTWVMDPPRVIDVTGFFNLVLVWNRGISFGVMNNHGEW
CCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHEEHHEECCCCEEEEECCCCCH
NAAILSALALVIAGSLTWWLRRAETRWQRLALPLIIGGAIGNVIDRLIHGAVVDFVDLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGYHWPAFNVADAAITVGAILLLIDTLVHRPPVGTDKAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
APALSLAALVIALDQATKWAILTWVMDPPRVIDVTGFFNLVLVWNRGISFGVMNNHGEW
CCHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEEHHHHEEHHEECCCCEEEEECCCCCH
NAAILSALALVIAGSLTWWLRRAETRWQRLALPLIIGGAIGNVIDRLIHGAVVDFVDLSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
AGYHWPAFNVADAAITVGAILLLIDTLVHRPPVGTDKAGG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA