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The map label for this gene is tsaA [H]

Identifier: 83594229

GI number: 83594229

Start: 3339713

End: 3340327

Strand: Direct

Name: tsaA [H]

Synonym: Rru_A2897

Alternate gene names: 83594229

Gene position: 3339713-3340327 (Clockwise)

Preceding gene: 83594223

Following gene: 83594230

Centisome position: 76.73

GC content: 63.41

Gene sequence:

>615_bases
ATGACCGAAAGTGTTGGTACCCTGACCGGCCGGCCGGTCCCTGATTTCACCGCCCCGGCGGTGCTGGCGGACAATTCCAT
TGTCGAAGATTTCTGTTTGAAGGACTATCTGGCGGGGTTTTATGGCCTGATTTTCTTCTATCCGCTGGATTTCACCTTCG
TCTGTCCCTCGGAAATCCTCGCCCACGACCACCGCCTGCCCGCCTTCGCCGCCAAGGAGGCCAAGGTGGTGGCGATTTCG
GTCGATTCCCAATACAGCCATCTCGCCTGGAAGAAGACGCCGATCGCCGAGGGCGGCCTGGGCCCGATCGGCTTTCCGAT
GGTGGCCGACATCAGCAAGGCGATCGCCCGCTCGTTCGGGGTGCTGCTGGAAACCGGCGTCGCCTTGCGCGCCAGCTTCC
TGGTCGATCGCGGCGGCATCGTCCGCCATCAAACGGTCAATGACCTGCCTTTGGGCCGCAATGTCGATGAAACCCTGCGC
ATGATCGACGCCCTGCGCTTTCACGACGCCCATGGCCAAGTCTGCCCCGCCGGCTGGAAGACCGGCGATCCGGGGATGAC
CGCCAGCCCCGAGGGGGTCGCGGCCTATCTTTCGGCCAACGCCGAGCGCCTTTAG

Upstream 100 bases:

>100_bases
AAAGCGCGCTGCACGGGTGGAAGCCCCTGTGGGCGGGGGTGGCTCGTATCGGGGCGCTTTTTATGGAGCCCCATCGCCAA
AATCCAGGGATTTATCCGCG

Downstream 100 bases:

>100_bases
GACCGGGACGCGGTAAGGCCCCTTCCGCCCCGGGCGCGGTACCCGGGCGCGGTTACCGCTTTTGCTTTACCCCGGCGGAC
GGGCCCTCTATCCTTTATAC

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: 26 kDa antigen; Thioredoxin reductase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MTESVGTLTGRPVPDFTAPAVLADNSIVEDFCLKDYLAGFYGLIFFYPLDFTFVCPSEILAHDHRLPAFAAKEAKVVAIS
VDSQYSHLAWKKTPIAEGGLGPIGFPMVADISKAIARSFGVLLETGVALRASFLVDRGGIVRHQTVNDLPLGRNVDETLR
MIDALRFHDAHGQVCPAGWKTGDPGMTASPEGVAAYLSANAERL

Sequences:

>Translated_204_residues
MTESVGTLTGRPVPDFTAPAVLADNSIVEDFCLKDYLAGFYGLIFFYPLDFTFVCPSEILAHDHRLPAFAAKEAKVVAIS
VDSQYSHLAWKKTPIAEGGLGPIGFPMVADISKAIARSFGVLLETGVALRASFLVDRGGIVRHQTVNDLPLGRNVDETLR
MIDALRFHDAHGQVCPAGWKTGDPGMTASPEGVAAYLSANAERL
>Mature_203_residues
TESVGTLTGRPVPDFTAPAVLADNSIVEDFCLKDYLAGFYGLIFFYPLDFTFVCPSEILAHDHRLPAFAAKEAKVVAISV
DSQYSHLAWKKTPIAEGGLGPIGFPMVADISKAIARSFGVLLETGVALRASFLVDRGGIVRHQTVNDLPLGRNVDETLRM
IDALRFHDAHGQVCPAGWKTGDPGMTASPEGVAAYLSANAERL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=192, Percent_Identity=47.3958333333333, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI32455266, Length=192, Percent_Identity=47.3958333333333, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI32455264, Length=192, Percent_Identity=47.3958333333333, Blast_Score=189, Evalue=2e-48,
Organism=Homo sapiens, GI32189392, Length=192, Percent_Identity=45.8333333333333, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI5453549, Length=188, Percent_Identity=47.8723404255319, Blast_Score=183, Evalue=1e-46,
Organism=Homo sapiens, GI5802974, Length=185, Percent_Identity=45.945945945946, Blast_Score=177, Evalue=7e-45,
Organism=Homo sapiens, GI32483377, Length=186, Percent_Identity=45.6989247311828, Blast_Score=176, Evalue=9e-45,
Organism=Homo sapiens, GI4758638, Length=191, Percent_Identity=30.8900523560209, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI33188454, Length=81, Percent_Identity=49.3827160493827, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786822, Length=153, Percent_Identity=34.640522875817, Blast_Score=96, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17554494, Length=200, Percent_Identity=48.5, Blast_Score=176, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=47.6190476190476, Blast_Score=172, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=47.6190476190476, Blast_Score=171, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI25153706, Length=185, Percent_Identity=28.1081081081081, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=42.1052631578947, Blast_Score=160, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6320661, Length=173, Percent_Identity=42.1965317919075, Blast_Score=147, Evalue=9e-37,
Organism=Saccharomyces cerevisiae, GI6319407, Length=175, Percent_Identity=29.7142857142857, Blast_Score=86, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24656348, Length=191, Percent_Identity=44.5026178010471, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI17864676, Length=191, Percent_Identity=44.5026178010471, Blast_Score=186, Evalue=8e-48,
Organism=Drosophila melanogaster, GI17157991, Length=192, Percent_Identity=44.7916666666667, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24641739, Length=192, Percent_Identity=44.7916666666667, Blast_Score=178, Evalue=2e-45,
Organism=Drosophila melanogaster, GI17738015, Length=182, Percent_Identity=44.5054945054945, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21357347, Length=186, Percent_Identity=45.1612903225806, Blast_Score=164, Evalue=3e-41,
Organism=Drosophila melanogaster, GI24581278, Length=159, Percent_Identity=31.4465408805031, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17975518, Length=184, Percent_Identity=31.5217391304348, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24652434, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24652436, Length=184, Percent_Identity=30.9782608695652, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 21919; Mature: 21788

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESVGTLTGRPVPDFTAPAVLADNSIVEDFCLKDYLAGFYGLIFFYPLDFTFVCPSEIL
CCCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHH
AHDHRLPAFAAKEAKVVAISVDSQYSHLAWKKTPIAEGGLGPIGFPMVADISKAIARSFG
HCCCCCCCEECCCCEEEEEEECCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VLLETGVALRASFLVDRGGIVRHQTVNDLPLGRNVDETLRMIDALRFHDAHGQVCPAGWK
HHHHHCHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
TGDPGMTASPEGVAAYLSANAERL
CCCCCCCCCCCHHEEEECCCCCCC
>Mature Secondary Structure 
TESVGTLTGRPVPDFTAPAVLADNSIVEDFCLKDYLAGFYGLIFFYPLDFTFVCPSEIL
CCCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCHHHH
AHDHRLPAFAAKEAKVVAISVDSQYSHLAWKKTPIAEGGLGPIGFPMVADISKAIARSFG
HCCCCCCCEECCCCEEEEEEECCCCCHHEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
VLLETGVALRASFLVDRGGIVRHQTVNDLPLGRNVDETLRMIDALRFHDAHGQVCPAGWK
HHHHHCHHHHHHHHHCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCC
TGDPGMTASPEGVAAYLSANAERL
CCCCCCCCCCCHHEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 1987145 [H]