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The map label for this gene is moaC

Identifier: 83594145

GI number: 83594145

Start: 3246427

End: 3246927

Strand: Direct

Name: moaC

Synonym: Rru_A2813

Alternate gene names: 83594145

Gene position: 3246427-3246927 (Clockwise)

Preceding gene: 83594144

Following gene: 83594146

Centisome position: 74.58

GC content: 68.46

Gene sequence:

>501_bases
ATGACGGACCCCGCCCCCGCCACTGCCGACGGGCTGACCCATTTCGATACGGCGGGCAACGCCGTGATGGTCGATGTCTC
GGCCAAGGATGAGACCGAACGGGTGGCCGTGGCCGGCGGCTGCGTGGAAATGGCGCCGGCCACCCTGCGCGCCATCATCG
AGCGCGGCCTGAAAAAGGGCGACGTGCTGAGCGTGGCCCAGTTGGCCGGCATCATGGGCGCCAAGCGCACCCCCGATCTG
ATCCCGCTGTGCCATCCTTTGGCCCTGACCAAGGTCGCCGTCGAGCTGACCCCCGACCCCGACCATGACCGGGTGGTGAT
CACCGCCACCTGCGCCCTGCGCGGGCGGACCGGCGTCGAGATGGAGGCGCTGACCGCCGTCGCCGTCGCCGGACTCACGG
TTTATGACATGTGCAAGGCCGTCGATAAGGGCATGCGCCTGACCGATATCCGGCTGCTGTCCAAAACCGGCGGCAAGTCG
GGGACCTGGACCGCCTCCTAA

Upstream 100 bases:

>100_bases
TCCGCGGCCTTGCCACCACCCGCCTCGCCCGCCGGATGGCGCGGACACATCCCTGAGCCGCCCCGCCGGTGCTGGAGTTT
CGACCACAGGAGTTTCCCCG

Downstream 100 bases:

>100_bases
TCGTGACGCGGTGAGCGGGGACCAGATCTCGCGCTCGCCGCTCCAGGGGATTTTCTCTGGGCTTCGCGCTCGCCGGGGCG
GGCCCCATGACCAAAGGACA

Product: GTP cyclohydrolase subunit MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKGDVLSVAQLAGIMGAKRTPDL
IPLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVEMEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKS
GTWTAS

Sequences:

>Translated_166_residues
MTDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKGDVLSVAQLAGIMGAKRTPDL
IPLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVEMEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKS
GTWTAS
>Mature_165_residues
TDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKGDVLSVAQLAGIMGAKRTPDLI
PLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVEMEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKSG
TWTAS

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family

Homologues:

Organism=Escherichia coli, GI1787001, Length=152, Percent_Identity=59.2105263157895, Blast_Score=171, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32566331, Length=153, Percent_Identity=50.3267973856209, Blast_Score=146, Evalue=5e-36,
Organism=Drosophila melanogaster, GI28574490, Length=148, Percent_Identity=54.7297297297297, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI28574492, Length=137, Percent_Identity=54.7445255474453, Blast_Score=139, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOAC_RHORT (Q2RQI5)

Other databases:

- EMBL:   CP000230
- RefSeq:   YP_427897.1
- ProteinModelPortal:   Q2RQI5
- SMR:   Q2RQI5
- STRING:   Q2RQI5
- GeneID:   3836253
- GenomeReviews:   CP000230_GR
- KEGG:   rru:Rru_A2813
- NMPDR:   fig|1085.1.peg.458
- eggNOG:   COG0315
- HOGENOM:   HBG605231
- OMA:   PMCHPLM
- PhylomeDB:   Q2RQI5
- ProtClustDB:   CLSK745126
- BioCyc:   RRUB269796:RRU_A2813-MONOMER
- HAMAP:   MF_01224_B
- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820
- Gene3D:   G3DSA:3.30.70.640
- TIGRFAMs:   TIGR00581

Pfam domain/function: PF01967 MoaC; SSF55040 MoaC

EC number: NA

Molecular weight: Translated: 17227; Mature: 17096

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: ACT_SITE 136-136

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKG
CCCCCCCCCCCCEEECCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCC
DVLSVAQLAGIMGAKRTPDLIPLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVE
CHHHHHHHHHHHCCCCCCCCCCHHCHHEEEEEEEEECCCCCCCEEEEEEEEEECCCCCCC
MEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKSGTWTAS
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TDPAPATADGLTHFDTAGNAVMVDVSAKDETERVAVAGGCVEMAPATLRAIIERGLKKG
CCCCCCCCCCCEEECCCCCEEEEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCC
DVLSVAQLAGIMGAKRTPDLIPLCHPLALTKVAVELTPDPDHDRVVITATCALRGRTGVE
CHHHHHHHHHHHCCCCCCCCCCHHCHHEEEEEEEEECCCCCCCEEEEEEEEEECCCCCCC
MEALTAVAVAGLTVYDMCKAVDKGMRLTDIRLLSKTGGKSGTWTAS
HHHHHHHHHHHHHHHHHHHHHHCCCEEHHEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA