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The map label for this gene is lysX [H]

Identifier: 83594096

GI number: 83594096

Start: 3198383

End: 3199852

Strand: Reverse

Name: lysX [H]

Synonym: Rru_A2764

Alternate gene names: 83594096

Gene position: 3199852-3198383 (Counterclockwise)

Preceding gene: 83594097

Following gene: 83594095

Centisome position: 73.51

GC content: 61.9

Gene sequence:

>1470_bases
ATGCTTTTCATTTTGTCCGAACGCAAGCCCGAGACCTTCCCGGCGGACGTGGCCGATCTGATTGTCGCCCCCCGCGAGTT
CATTTCCCGCCCGGCGCTGTTTTCGGCCCCGGGGACCCGCATCATCAATCTGGCCAGCGATTGCTCCTATCTGGGGCTGG
GCTATTACGCCTCGCTGCTGGCGGCGGCGCGCGGCCTGAAGGTGCTGCCCGCCGTTGCCGCCATCGTCAATCTGAACCGC
AAATCCCTGCGCCAGATCCTGATGCGCGGTCTGAACGACGCGCTTGATATCCGCATGGGAGACCTGGGCGAAACCGAAGC
CCAGCCATTCGAGGTGTTCATCGCCTTTGGCGCCACCCCCGATGCGCGCTTTGGCAAGTTGGCCCGTCAGGTGTGGGAGG
CATTTCAGTTTCCGCTGATGGTGATGACCATCGCTCCGGTGGCGGGCGGGTCGGGCTGGCAGATCCAGGATATCGAGCCG
CGCTCGGCCAAGGATCTTCCCGAAGACCGCGAGAGCTTTTTCCAAGAGCAACTGGCCAAGGCGCTGAAGGACGAATGGAA
ACCGCCCAAGCCGCGCAAGGCGCCGAAATGGTCGCTGGCGGTGCTGTATAACCGCGAGGATCCCCTGCCGCCCTCGACGG
CGCCGACGCTACGCAAGCTGAGCCGGGCGGCGGCCAGGGCCGGGGTCGAGGTGGAGGTGATCGGCAAGAAGGATCTGCCG
CGTCTGGCGGAATTCGACGCCCTGTTCATCCGCGAGACGACCAACGTCAACCACCACACCTTCACCTTCGCCCGCACCGC
CGAGGAAAACGGCATGCCGGTGATCGATGATTCGCTGTCGATCCTGCGCTGTACCAACAAGGTCTATCTGGCCGAGCTGC
TGGCGGCCAATAATCTGCCGACCCCGGAAACCCGGGTGATCGATCGCCAGCGGCTGAAAACGGTTGAACGCTATCTGAGC
TACCCGATCGTCCTCAAGATCCCCGACGGCAGTTTTTCGCGTGGGGTGGTCAAGGTCGAAGACCGGGCCGCGCTGCTTGA
TGTCGGCCATAAGCTGCTGGGCTCGTCGGATCTGATCCTCGCCCAGGAATTCGTACCCACCGCCTTTGATTGGCGGGTTG
GCGTGCTCAACGGCCAGCCGCTGTTCGTCTGCCAGTATCTGATGAGCCGCAAGCATTGGCAGATCGTTAATCACAACGCC
AATGGCAAGACCGAACTGGGAAGCTGTAAGACCCTGGATATCGATCAAGCCCCCCACGAGGTCATCGCCCTTGCCCTGCG
CGCGGCCAATCTGATGGGCAACGGGCTTTATGGCGTCGATATCAAACAAACCGAAAAGGGCTGTCTGGTGATCGAGGTCA
ACGACAACCCCAATATCGATACCGGCATCGAGGATCAGGTGCTTAAGGGCGCCTTGTACGACACGCTGATCGGCGAGTTC
GTGCGTCGCCTCGAAGAGGCGCGGAGTTAG

Upstream 100 bases:

>100_bases
CCATTCCCCGGCGCGATTTTCAGGCGATGGCTCGCTATGGCCGTTCCCGGCTGCGCGCCGCCGTGGTGATACGCCGCGCC
ACCTTCTGACGGACCCACAA

Downstream 100 bases:

>100_bases
TCGCCTCGAAGAGGCGCGGAGTTAGAATCTCGAAGAGGCGCGGAGCTAGAGTCTCGAAGAGGCGCGGGGCGAGAGTCATC
TATCGGTCAGGGATAACCAC

Product: hypothetical protein

Products: NA

Alternate protein names: AAA--lysW ligase lysX [H]

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MLFILSERKPETFPADVADLIVAPREFISRPALFSAPGTRIINLASDCSYLGLGYYASLLAAARGLKVLPAVAAIVNLNR
KSLRQILMRGLNDALDIRMGDLGETEAQPFEVFIAFGATPDARFGKLARQVWEAFQFPLMVMTIAPVAGGSGWQIQDIEP
RSAKDLPEDRESFFQEQLAKALKDEWKPPKPRKAPKWSLAVLYNREDPLPPSTAPTLRKLSRAAARAGVEVEVIGKKDLP
RLAEFDALFIRETTNVNHHTFTFARTAEENGMPVIDDSLSILRCTNKVYLAELLAANNLPTPETRVIDRQRLKTVERYLS
YPIVLKIPDGSFSRGVVKVEDRAALLDVGHKLLGSSDLILAQEFVPTAFDWRVGVLNGQPLFVCQYLMSRKHWQIVNHNA
NGKTELGSCKTLDIDQAPHEVIALALRAANLMGNGLYGVDIKQTEKGCLVIEVNDNPNIDTGIEDQVLKGALYDTLIGEF
VRRLEEARS

Sequences:

>Translated_489_residues
MLFILSERKPETFPADVADLIVAPREFISRPALFSAPGTRIINLASDCSYLGLGYYASLLAAARGLKVLPAVAAIVNLNR
KSLRQILMRGLNDALDIRMGDLGETEAQPFEVFIAFGATPDARFGKLARQVWEAFQFPLMVMTIAPVAGGSGWQIQDIEP
RSAKDLPEDRESFFQEQLAKALKDEWKPPKPRKAPKWSLAVLYNREDPLPPSTAPTLRKLSRAAARAGVEVEVIGKKDLP
RLAEFDALFIRETTNVNHHTFTFARTAEENGMPVIDDSLSILRCTNKVYLAELLAANNLPTPETRVIDRQRLKTVERYLS
YPIVLKIPDGSFSRGVVKVEDRAALLDVGHKLLGSSDLILAQEFVPTAFDWRVGVLNGQPLFVCQYLMSRKHWQIVNHNA
NGKTELGSCKTLDIDQAPHEVIALALRAANLMGNGLYGVDIKQTEKGCLVIEVNDNPNIDTGIEDQVLKGALYDTLIGEF
VRRLEEARS
>Mature_489_residues
MLFILSERKPETFPADVADLIVAPREFISRPALFSAPGTRIINLASDCSYLGLGYYASLLAAARGLKVLPAVAAIVNLNR
KSLRQILMRGLNDALDIRMGDLGETEAQPFEVFIAFGATPDARFGKLARQVWEAFQFPLMVMTIAPVAGGSGWQIQDIEP
RSAKDLPEDRESFFQEQLAKALKDEWKPPKPRKAPKWSLAVLYNREDPLPPSTAPTLRKLSRAAARAGVEVEVIGKKDLP
RLAEFDALFIRETTNVNHHTFTFARTAEENGMPVIDDSLSILRCTNKVYLAELLAANNLPTPETRVIDRQRLKTVERYLS
YPIVLKIPDGSFSRGVVKVEDRAALLDVGHKLLGSSDLILAQEFVPTAFDWRVGVLNGQPLFVCQYLMSRKHWQIVNHNA
NGKTELGSCKTLDIDQAPHEVIALALRAANLMGNGLYGVDIKQTEKGCLVIEVNDNPNIDTGIEDQVLKGALYDTLIGEF
VRRLEEARS

Specific function: Catalyzes the ATP-dependent binding between the amino group of alpha-aminoadipate (AAA) and the gamma-carboxyl group of the C-terminal glutamate residue of lysW (Probable) [H]

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011870
- InterPro:   IPR016185
- InterPro:   IPR004666 [H]

Pfam domain/function: PF08443 RimK [H]

EC number: NA

Molecular weight: Translated: 54255; Mature: 54255

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFILSERKPETFPADVADLIVAPREFISRPALFSAPGTRIINLASDCSYLGLGYYASLL
CEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHH
AAARGLKVLPAVAAIVNLNRKSLRQILMRGLNDALDIRMGDLGETEAQPFEVFIAFGATP
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCEEEEEEECCCC
DARFGKLARQVWEAFQFPLMVMTIAPVAGGSGWQIQDIEPRSAKDLPEDRESFFQEQLAK
CHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
ALKDEWKPPKPRKAPKWSLAVLYNREDPLPPSTAPTLRKLSRAAARAGVEVEVIGKKDLP
HHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
RLAEFDALFIRETTNVNHHTFTFARTAEENGMPVIDDSLSILRCTNKVYLAELLAANNLP
HHHHHCEEEEEECCCCCCEEEEEEEECCCCCCCEECCCCHHHHHCCHHHHHHHHHHCCCC
TPETRVIDRQRLKTVERYLSYPIVLKIPDGSFSRGVVKVEDRAALLDVGHKLLGSSDLIL
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEE
AQEFVPTAFDWRVGVLNGQPLFVCQYLMSRKHWQIVNHNANGKTELGSCKTLDIDQAPHE
HHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEECCCCCHHH
VIALALRAANLMGNGLYGVDIKQTEKGCLVIEVNDNPNIDTGIEDQVLKGALYDTLIGEF
HHHHHHHHHHHHCCCEEECEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
VRRLEEARS
HHHHHHHCC
>Mature Secondary Structure
MLFILSERKPETFPADVADLIVAPREFISRPALFSAPGTRIINLASDCSYLGLGYYASLL
CEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCEECCCCCEEEEECCCCCHHHHHHHHHHH
AAARGLKVLPAVAAIVNLNRKSLRQILMRGLNDALDIRMGDLGETEAQPFEVFIAFGATP
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCHHHEEEECCCCCCCCCCEEEEEEECCCC
DARFGKLARQVWEAFQFPLMVMTIAPVAGGSGWQIQDIEPRSAKDLPEDRESFFQEQLAK
CHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
ALKDEWKPPKPRKAPKWSLAVLYNREDPLPPSTAPTLRKLSRAAARAGVEVEVIGKKDLP
HHHHCCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCC
RLAEFDALFIRETTNVNHHTFTFARTAEENGMPVIDDSLSILRCTNKVYLAELLAANNLP
HHHHHCEEEEEECCCCCCEEEEEEEECCCCCCCEECCCCHHHHHCCHHHHHHHHHHCCCC
TPETRVIDRQRLKTVERYLSYPIVLKIPDGSFSRGVVKVEDRAALLDVGHKLLGSSDLIL
CCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEECCHHHHHHHHHHHHCCCCEEE
AQEFVPTAFDWRVGVLNGQPLFVCQYLMSRKHWQIVNHNANGKTELGSCKTLDIDQAPHE
HHHHCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEEECCCCCCCCCCCCEEECCCCCHHH
VIALALRAANLMGNGLYGVDIKQTEKGCLVIEVNDNPNIDTGIEDQVLKGALYDTLIGEF
HHHHHHHHHHHHCCCEEECEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
VRRLEEARS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11427726; 12042311 [H]