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The map label for this gene is rfbD [C]

Identifier: 83594066

GI number: 83594066

Start: 3162319

End: 3163224

Strand: Direct

Name: rfbD [C]

Synonym: Rru_A2734

Alternate gene names: 83594066

Gene position: 3162319-3163224 (Clockwise)

Preceding gene: 83594065

Following gene: 83594067

Centisome position: 72.65

GC content: 68.98

Gene sequence:

>906_bases
GTGGCGGAAAAGCGTATCCTTGTCCTTGGCGCCCATGGCATGGCCGGCCACGTGTTGCTCGCCGGTCTGCGGGCCGCCGG
TCATGACTGCTGGGGAACCGTCCGCGACGCCCTGCCCGCGCCCTCCCAGCCGTCCGCCGATCCCCAACTGGTTGGCGGCG
TCGACGCCATGGCCCCCGGGTCCTTAGCGGACCTGCTCGATGCGCTTCGTCCCGCCGTCGTCGTCAACGCCATCGGCATC
ATCAAGCAACGCCCCGAAGCCCAGGACCCGGTTGTCGCCATCACCGTCAACGCCCTGTTCCCCCAGATCCTTGCCAATCT
CTGCCGGGCCCGCACCCTGCGCCTGATCCACCTGTCCACCGATTGCGTGTTTTCGGGAACGGCCGGCGGCTATGACGAAG
ACAGCCCCGCCGCGCCGCCCGATCTGTATGGACGCTCAAAGCTGCTGGGCGAGGTCGACGGGCCGGGGTGCCTGACCCTG
CGCACCTCGATCATCGGCCCCGGCCTGCGCCCCGGGCCTGGGCTGGTCGACTGGCTGCTCGCCCAGCGCGGCGGCCGGGT
TACCGGTTATGCCAAGGCCCTGTTCAGCGGCCTGACCACCGTTGATCTCTGCGCCCTGATCGCCCGGCTGATATCCGACT
TTCCGCGGCTTGATGGGCTTTACCACGCCGCCGCCGCCCCCATTTCCAAATACGACCTGCTTCACCTGCTCAACGACGCC
CTGGCCCTTGATCTGACCATTCTACGCGACGAAAGCGTCGTCGTGGACCGCAGCCTATCGGCCGCCCGCCTGAGCGCCGC
GACCGGGTGGAGCGCCCCCCCCTGGCCGATCATGGTTTCCCATCTGGCCGCGCACATCGCCGCGACGGCGCCCGCCAAAA
CCGCTGAAGGATCCCCCCCGCCGTGA

Upstream 100 bases:

>100_bases
ATCCCGATATTTTCCGACGGCTTTGTTCTATTATTGACTATTCCTAACAAGATCCGGGCTGATCGCTTTTTTTTCAGGAA
GAAGGGAGGGTGAGTTTACT

Downstream 100 bases:

>100_bases
AAACCAATCTGGAGCACTGGGTCACCCTTCAGGAAAAGGGATATTTCGAAAACCATCCCTTTTACCAGGAGCGGCAGGTC
AACGACGACGCCGCCCGCGT

Product: dTDP-4-dehydrorhamnose reductase

Products: dTDP-4-dehydro-6-deoxy-L-mannose; NADPH; H+

Alternate protein names: Carbohydrate Oxidoreductase; NAD-Dependent Epimerase/Dehydratase; Reductase; LPS Biosynthesis Related Reductase; TDP-4-Keto-L-Rhamnose Reductase.; DTDP-4-Keto-L-Rhamnose Reductase; Dtdp-4-Dehydrorhamnose Reductase Protein; Sugar Oxidoreductase; NAD Dependent Epimerase/Dehydratase

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MAEKRILVLGAHGMAGHVLLAGLRAAGHDCWGTVRDALPAPSQPSADPQLVGGVDAMAPGSLADLLDALRPAVVVNAIGI
IKQRPEAQDPVVAITVNALFPQILANLCRARTLRLIHLSTDCVFSGTAGGYDEDSPAAPPDLYGRSKLLGEVDGPGCLTL
RTSIIGPGLRPGPGLVDWLLAQRGGRVTGYAKALFSGLTTVDLCALIARLISDFPRLDGLYHAAAAPISKYDLLHLLNDA
LALDLTILRDESVVVDRSLSAARLSAATGWSAPPWPIMVSHLAAHIAATAPAKTAEGSPPP

Sequences:

>Translated_301_residues
MAEKRILVLGAHGMAGHVLLAGLRAAGHDCWGTVRDALPAPSQPSADPQLVGGVDAMAPGSLADLLDALRPAVVVNAIGI
IKQRPEAQDPVVAITVNALFPQILANLCRARTLRLIHLSTDCVFSGTAGGYDEDSPAAPPDLYGRSKLLGEVDGPGCLTL
RTSIIGPGLRPGPGLVDWLLAQRGGRVTGYAKALFSGLTTVDLCALIARLISDFPRLDGLYHAAAAPISKYDLLHLLNDA
LALDLTILRDESVVVDRSLSAARLSAATGWSAPPWPIMVSHLAAHIAATAPAKTAEGSPPP
>Mature_300_residues
AEKRILVLGAHGMAGHVLLAGLRAAGHDCWGTVRDALPAPSQPSADPQLVGGVDAMAPGSLADLLDALRPAVVVNAIGII
KQRPEAQDPVVAITVNALFPQILANLCRARTLRLIHLSTDCVFSGTAGGYDEDSPAAPPDLYGRSKLLGEVDGPGCLTLR
TSIIGPGLRPGPGLVDWLLAQRGGRVTGYAKALFSGLTTVDLCALIARLISDFPRLDGLYHAAAAPISKYDLLHLLNDAL
ALDLTILRDESVVVDRSLSAARLSAATGWSAPPWPIMVSHLAAHIAATAPAKTAEGSPPP

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG1091

COG function: function code M; dTDP-4-dehydrorhamnose reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.1.1.133

Molecular weight: Translated: 31239; Mature: 31108

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKRILVLGAHGMAGHVLLAGLRAAGHDCWGTVRDALPAPSQPSADPQLVGGVDAMAPG
CCCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCC
SLADLLDALRPAVVVNAIGIIKQRPEAQDPVVAITVNALFPQILANLCRARTLRLIHLST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEEEEEEC
DCVFSGTAGGYDEDSPAAPPDLYGRSKLLGEVDGPGCLTLRTSIIGPGLRPGPGLVDWLL
CEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHCCCCCCCCCHHHHHHH
AQRGGRVTGYAKALFSGLTTVDLCALIARLISDFPRLDGLYHAAAAPISKYDLLHLLNDA
HHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LALDLTILRDESVVVDRSLSAARLSAATGWSAPPWPIMVSHLAAHIAATAPAKTAEGSPP
HHHEEEEECCCCEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
P
C
>Mature Secondary Structure 
AEKRILVLGAHGMAGHVLLAGLRAAGHDCWGTVRDALPAPSQPSADPQLVGGVDAMAPG
CCCEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCC
SLADLLDALRPAVVVNAIGIIKQRPEAQDPVVAITVNALFPQILANLCRARTLRLIHLST
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHEEEEEEEC
DCVFSGTAGGYDEDSPAAPPDLYGRSKLLGEVDGPGCLTLRTSIIGPGLRPGPGLVDWLL
CEEEECCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHCCCCCCCCCHHHHHHH
AQRGGRVTGYAKALFSGLTTVDLCALIARLISDFPRLDGLYHAAAAPISKYDLLHLLNDA
HHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
LALDLTILRDESVVVDRSLSAARLSAATGWSAPPWPIMVSHLAAHIAATAPAKTAEGSPP
HHHEEEEECCCCEEEECCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-6-deoxy-L-mannose; NADP+

Specific reaction: dTDP-6-deoxy-L-mannose + NADP+ = dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA