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The map label for this gene is adrA [H]

Identifier: 83593563

GI number: 83593563

Start: 2587054

End: 2588706

Strand: Reverse

Name: adrA [H]

Synonym: Rru_A2228

Alternate gene names: 83593563

Gene position: 2588706-2587054 (Counterclockwise)

Preceding gene: 83593564

Following gene: 83593558

Centisome position: 59.47

GC content: 71.08

Gene sequence:

>1653_bases
ATGAGCATGTTTGACTTGCAAGATCGGTTGCGCGGCGCCGTCAGCGCTTTCGTCGAGGGGGCGATCGTCAGCGCCGAGGC
CATCGCCCCCCGGCTTGATCTGTTGCGGGCCAGCGGATGGGCCGATGAGGACGCGGCGGCCGATGTCTCGCATTTCGTTC
ACCGTCTGGCCGGCACCGCCGGCACCTTGGGATTTGGCGATCTCGGGCGGACCGCCGGCGCCCTGGAAACCCTGATCGCC
GATATCGGCGAGGTGCGACTGGCCGAGGGAGCGGCGGCCGTCGCCCCCGATATCCTGGCCCAGGCCGACTTGCTGGCCGA
TATCATTCTCGCCGGGCTGAAGGGCGTCGCGGTCGGCGGCTCCGATCTGCTGGCGGCGGCGATGACGCCGGCGCCGGGTT
TGGCCGGCTCGCCCGACCCGGCGGTGGTGGCGACCATCGGCGCCGGACCGGCGCTGCTCGACATGGTGCGCGCCACTGGC
ACCACCGCCATCGAAATCGCCTCGCCCGACGCCTTGGAAGCCCTGTCGGTCGTCTGCCCCGGCGGGGTGATCGTCAATCT
GGAGGCGATGGACGGCGACGACGCGTGGCGCGGACCGCTTGATGGTCTGCGCGCCCAGGGCGTTCCGGTTCTGGCGGTCG
GCGGAACGGGCGATTTTCCCTGGGGGCTGCGAGCCTGCCGCCTTGGCGTCGACGCCTATCTGCCCCTGGATGATCCGGGC
GAAGTGCTTGACCGGCTGGCGCGGATGCGCCTCACCCGCCACGCCGAACCGCTGCGCGTGCTGGTGCTTGATGACGACGC
GGTGTTGGCGGGGGTTTACGCGACGATCCTGGGGGCGGCCGGTCTGGAGGCCGAGGGGATGACCGATCCCGCCCAGATCC
TGGAACGGCTGGAGGCTTTCGAGCCCGATGTGCTGGTGACCGATCTGCACATGCCCGGCTGTTCGGGCGCCGAGGTCGCC
GCCCTGGTTCGCCACCGCGCCCAATACGCCACGATGCCGATTATCTTCCTGTCACGGGAACAAGATCTGGGGCTGCAGCT
TGGGGCCCTGAGCCCGGGGGCGGATTTCTTCCTGCCCAAGCCGGTGCGGCCCGATTTCCTGGTTTCGGCGGTCCGCTCGC
GGGCCCGGCGCGGGCGCGGATTGGCCGAGATGATGCGGCGCGACGGGTTGAGCCGGCTGTTCACCCATTCCACCATTCTT
GACGGCCTGGAGCGCGAGGGGGCGCGGGCCGGCCGCACCGGGGCGCCGCTGTCCTTCGCCCTGCTCGATCTCGATCACTT
CAAGGCGATCAACCAGACCCATGGCCACGCGACGGGCGATCAGGTGATCGTGACCCTGGCCCGGGTGATGCGGCGCGCCC
TGCGTGGGTGCGACCTGCTGGGGCGCTGCGGCGGCGAGGAATTCGCCGTCATCCTGCCCGGAACCCCGGCCGAGCAAGCG
GTCGGCGTCATTGAGGATCTGCGGGCCCTGTTTCGCGGCCAAACCCTGCGAGCCCCCACCGGCGAGGTTCGCGCCACCTT
CAGCGCCGGCGTCGCCGGCACGCCGGCCGGGGCGCCCCCCCTATCGGCCACGGCGCTGTTCACCGCCGCCGACAAGGCCC
TGGCCGAGGCCAAGGCGCGCGGCCGCGACCGCGTGGTGCTGGCGGAAAGCTAG

Upstream 100 bases:

>100_bases
GAGTGCTGATGGCCGAACCCGGTTGCCTTGGCTTGATCACCAAACCTTTCGATCCGCTGACCCTGGCGGACTCCCTGCGC
CAGCTATGGATGGCCCGGTC

Downstream 100 bases:

>100_bases
GGGGAGAGGGCTGTTTGCCGCGGTGATCGTCAGGCCACCCATTCTTTTCGCAAGAGGGCGTACTGCATCGTGTTTTCGAA
GACCGGCACGCCTTCGTCAT

Product: response regulator receiver modulated diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSMFDLQDRLRGAVSAFVEGAIVSAEAIAPRLDLLRASGWADEDAAADVSHFVHRLAGTAGTLGFGDLGRTAGALETLIA
DIGEVRLAEGAAAVAPDILAQADLLADIILAGLKGVAVGGSDLLAAAMTPAPGLAGSPDPAVVATIGAGPALLDMVRATG
TTAIEIASPDALEALSVVCPGGVIVNLEAMDGDDAWRGPLDGLRAQGVPVLAVGGTGDFPWGLRACRLGVDAYLPLDDPG
EVLDRLARMRLTRHAEPLRVLVLDDDAVLAGVYATILGAAGLEAEGMTDPAQILERLEAFEPDVLVTDLHMPGCSGAEVA
ALVRHRAQYATMPIIFLSREQDLGLQLGALSPGADFFLPKPVRPDFLVSAVRSRARRGRGLAEMMRRDGLSRLFTHSTIL
DGLEREGARAGRTGAPLSFALLDLDHFKAINQTHGHATGDQVIVTLARVMRRALRGCDLLGRCGGEEFAVILPGTPAEQA
VGVIEDLRALFRGQTLRAPTGEVRATFSAGVAGTPAGAPPLSATALFTAADKALAEAKARGRDRVVLAES

Sequences:

>Translated_550_residues
MSMFDLQDRLRGAVSAFVEGAIVSAEAIAPRLDLLRASGWADEDAAADVSHFVHRLAGTAGTLGFGDLGRTAGALETLIA
DIGEVRLAEGAAAVAPDILAQADLLADIILAGLKGVAVGGSDLLAAAMTPAPGLAGSPDPAVVATIGAGPALLDMVRATG
TTAIEIASPDALEALSVVCPGGVIVNLEAMDGDDAWRGPLDGLRAQGVPVLAVGGTGDFPWGLRACRLGVDAYLPLDDPG
EVLDRLARMRLTRHAEPLRVLVLDDDAVLAGVYATILGAAGLEAEGMTDPAQILERLEAFEPDVLVTDLHMPGCSGAEVA
ALVRHRAQYATMPIIFLSREQDLGLQLGALSPGADFFLPKPVRPDFLVSAVRSRARRGRGLAEMMRRDGLSRLFTHSTIL
DGLEREGARAGRTGAPLSFALLDLDHFKAINQTHGHATGDQVIVTLARVMRRALRGCDLLGRCGGEEFAVILPGTPAEQA
VGVIEDLRALFRGQTLRAPTGEVRATFSAGVAGTPAGAPPLSATALFTAADKALAEAKARGRDRVVLAES
>Mature_549_residues
SMFDLQDRLRGAVSAFVEGAIVSAEAIAPRLDLLRASGWADEDAAADVSHFVHRLAGTAGTLGFGDLGRTAGALETLIAD
IGEVRLAEGAAAVAPDILAQADLLADIILAGLKGVAVGGSDLLAAAMTPAPGLAGSPDPAVVATIGAGPALLDMVRATGT
TAIEIASPDALEALSVVCPGGVIVNLEAMDGDDAWRGPLDGLRAQGVPVLAVGGTGDFPWGLRACRLGVDAYLPLDDPGE
VLDRLARMRLTRHAEPLRVLVLDDDAVLAGVYATILGAAGLEAEGMTDPAQILERLEAFEPDVLVTDLHMPGCSGAEVAA
LVRHRAQYATMPIIFLSREQDLGLQLGALSPGADFFLPKPVRPDFLVSAVRSRARRGRGLAEMMRRDGLSRLFTHSTILD
GLEREGARAGRTGAPLSFALLDLDHFKAINQTHGHATGDQVIVTLARVMRRALRGCDLLGRCGGEEFAVILPGTPAEQAV
GVIEDLRALFRGQTLRAPTGEVRATFSAGVAGTPAGAPPLSATALFTAADKALAEAKARGRDRVVLAES

Specific function: Unknown

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=319, Percent_Identity=31.0344827586207, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=171, Percent_Identity=35.0877192982456, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=35.4037267080745, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=36.3636363636364, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87081881, Length=131, Percent_Identity=39.6946564885496, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787802, Length=186, Percent_Identity=28.494623655914, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787816, Length=141, Percent_Identity=31.2056737588652, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788085, Length=185, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788381, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790299, Length=112, Percent_Identity=34.8214285714286, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 56970; Mature: 56839

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS50894 HPT ; PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMFDLQDRLRGAVSAFVEGAIVSAEAIAPRLDLLRASGWADEDAAADVSHFVHRLAGTA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
GTLGFGDLGRTAGALETLIADIGEVRLAEGAAAVAPDILAQADLLADIILAGLKGVAVGG
CCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SDLLAAAMTPAPGLAGSPDPAVVATIGAGPALLDMVRATGTTAIEIASPDALEALSVVCP
HHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCC
GGVIVNLEAMDGDDAWRGPLDGLRAQGVPVLAVGGTGDFPWGLRACRLGVDAYLPLDDPG
CCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCEECCCCCHH
EVLDRLARMRLTRHAEPLRVLVLDDDAVLAGVYATILGAAGLEAEGMTDPAQILERLEAF
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
EPDVLVTDLHMPGCSGAEVAALVRHRAQYATMPIIFLSREQDLGLQLGALSPGADFFLPK
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCC
PVRPDFLVSAVRSRARRGRGLAEMMRRDGLSRLFTHSTILDGLEREGARAGRTGAPLSFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LLDLDHFKAINQTHGHATGDQVIVTLARVMRRALRGCDLLGRCGGEEFAVILPGTPAEQA
EECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHH
VGVIEDLRALFRGQTLRAPTGEVRATFSAGVAGTPAGAPPLSATALFTAADKALAEAKAR
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GRDRVVLAES
CCCCEEEECC
>Mature Secondary Structure 
SMFDLQDRLRGAVSAFVEGAIVSAEAIAPRLDLLRASGWADEDAAADVSHFVHRLAGTA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
GTLGFGDLGRTAGALETLIADIGEVRLAEGAAAVAPDILAQADLLADIILAGLKGVAVGG
CCCCCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECC
SDLLAAAMTPAPGLAGSPDPAVVATIGAGPALLDMVRATGTTAIEIASPDALEALSVVCP
HHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHCCCCEEEECCCHHHHHHHHCCC
GGVIVNLEAMDGDDAWRGPLDGLRAQGVPVLAVGGTGDFPWGLRACRLGVDAYLPLDDPG
CCEEEEEEECCCCCCCCCCHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCEECCCCCHH
EVLDRLARMRLTRHAEPLRVLVLDDDAVLAGVYATILGAAGLEAEGMTDPAQILERLEAF
HHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
EPDVLVTDLHMPGCSGAEVAALVRHRAQYATMPIIFLSREQDLGLQLGALSPGADFFLPK
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCCCCCCCCC
PVRPDFLVSAVRSRARRGRGLAEMMRRDGLSRLFTHSTILDGLEREGARAGRTGAPLSFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEE
LLDLDHFKAINQTHGHATGDQVIVTLARVMRRALRGCDLLGRCGGEEFAVILPGTPAEQA
EECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEECCCCHHHH
VGVIEDLRALFRGQTLRAPTGEVRATFSAGVAGTPAGAPPLSATALFTAADKALAEAKAR
HHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHC
GRDRVVLAES
CCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]