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The map label for this gene is hflK [H]

Identifier: 83593538

GI number: 83593538

Start: 2558051

End: 2559274

Strand: Reverse

Name: hflK [H]

Synonym: Rru_A2203

Alternate gene names: 83593538

Gene position: 2559274-2558051 (Counterclockwise)

Preceding gene: 83593544

Following gene: 83593537

Centisome position: 58.8

GC content: 66.42

Gene sequence:

>1224_bases
ATGGGATGGAACCAGCAGGGAGGCGGCCCCTGGGGCGGCGGCGGGGGCGGCGGCGGCGGACCCTGGGGTAGTGGCGGGCG
CGGCGGCAACGGCCGGGGCTTTGGCGGCGGTTCGGGCGGCCAACCCCCCGATCTGGAAGAAATGCTGCGGCGGAGCCAAG
AGCGCTTTCGCAAGATGGTGCCCGGCGGCAATTTGGGCAACAAGGGGATCGGCCTAGTCGCGATCCTGGCCTTGGCCGTC
TGGTTGCTGACCGGGTTCTACCGGGTGGGCACCGACGAGCAGGGCGTGGTCATGCGCTTTGGCGAATTCACCCACACCAC
CCCGCCCGGGTTGCATTACCATCTGCCTTATCCCATCGAGGCGGTGATCCTTCCCAAGGTGACGGTTGAAAACCGCATCG
AGCTTGGCTTCCGCGGCATCGGTGAGAACGCCCGGGGCCGGACCCCCTCCCGCGACGTGCTGGAGGAAAGCCTGATGCTG
ACCGGTGACGAGAACATCATCGATATCGATTTCTCGGTCATCTGGGTGATCAAGGACGCCGGCGCCTTCCTGTTCAATCT
TCGCGACCCCGAAGGCACGGTCAACCGCGCCGCCGAAAGCGCCATGCGCGAGGTGATCGGCCAGACGCCGATCCAGGTGG
CTTTGACCGAAGGTCGTCAGCAGATCGAGGACCGGACCAAGGAACTGCTGCAGGCGATGATGGACGAATACAACGCCGGC
ATCACCATCCGCCGCGTCCAGTTGCTGAAAGTCGATCCGCCGGCCCAGGTCGTCGATGCCTTCAACGATGTCCAGCGCTC
GCGCGCCGATCGCGAACGCCTGCGCAACGAGGCCGAAGCCTATCGCAACTCGGTGATCCCCGAGGCTCGCGGCCAGGCCG
AGCAGTTGCTCCAGCAGGCGGAAGCCTATCGCGAGGAGATCGTCAACCGAGCCCAGGGCGACGTGGCCCGCTTTAATTCC
GTGCTCGAAGGCTATCGCCTCAACCGCGACGTCACCACCCAGCGCATCTACCTGGAAACCATGGAGGAGGTTCTGCGCAA
CGTGAACAAGGTGATCATCGACAAGAACGGTCAGGGTGTCGTGCCCTACCTGCCCTTGCCTGAAGTGCGCGCCCGCCAGG
GTGGCGCCGCCGCGATCGCCCCCTCGGGCCTGTCCGGGGCGCCCCTGCGGCCGATGTCCCAGCCGATTCCGGGGCTTCCC
GCCGCGCAGGGAGGCGGCCGATGA

Upstream 100 bases:

>100_bases
CAATGCGTCGGCTGCCCTATAACTCTGGATCCGGTGTGGTCATTGTCGACGGCGGCGGTATGGTGTTTCGAAGCTTTAAA
CGCGAAAGGGACTTCGTTCA

Downstream 100 bases:

>100_bases
GAAAGTCCCTGGTGGCTCTTGGCGTCGTCGCCGTCCTCGCGGTGATCGGACTCTATTCGTCGCTTTTCATCGTCAACCAG
ACCCAGCAGGCGCTGGTCTT

Product: HflK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 406

Protein sequence:

>407_residues
MGWNQQGGGPWGGGGGGGGGPWGSGGRGGNGRGFGGGSGGQPPDLEEMLRRSQERFRKMVPGGNLGNKGIGLVAILALAV
WLLTGFYRVGTDEQGVVMRFGEFTHTTPPGLHYHLPYPIEAVILPKVTVENRIELGFRGIGENARGRTPSRDVLEESLML
TGDENIIDIDFSVIWVIKDAGAFLFNLRDPEGTVNRAAESAMREVIGQTPIQVALTEGRQQIEDRTKELLQAMMDEYNAG
ITIRRVQLLKVDPPAQVVDAFNDVQRSRADRERLRNEAEAYRNSVIPEARGQAEQLLQQAEAYREEIVNRAQGDVARFNS
VLEGYRLNRDVTTQRIYLETMEEVLRNVNKVIIDKNGQGVVPYLPLPEVRARQGGAAAIAPSGLSGAPLRPMSQPIPGLP
AAQGGGR

Sequences:

>Translated_407_residues
MGWNQQGGGPWGGGGGGGGGPWGSGGRGGNGRGFGGGSGGQPPDLEEMLRRSQERFRKMVPGGNLGNKGIGLVAILALAV
WLLTGFYRVGTDEQGVVMRFGEFTHTTPPGLHYHLPYPIEAVILPKVTVENRIELGFRGIGENARGRTPSRDVLEESLML
TGDENIIDIDFSVIWVIKDAGAFLFNLRDPEGTVNRAAESAMREVIGQTPIQVALTEGRQQIEDRTKELLQAMMDEYNAG
ITIRRVQLLKVDPPAQVVDAFNDVQRSRADRERLRNEAEAYRNSVIPEARGQAEQLLQQAEAYREEIVNRAQGDVARFNS
VLEGYRLNRDVTTQRIYLETMEEVLRNVNKVIIDKNGQGVVPYLPLPEVRARQGGAAAIAPSGLSGAPLRPMSQPIPGLP
AAQGGGR
>Mature_406_residues
GWNQQGGGPWGGGGGGGGGPWGSGGRGGNGRGFGGGSGGQPPDLEEMLRRSQERFRKMVPGGNLGNKGIGLVAILALAVW
LLTGFYRVGTDEQGVVMRFGEFTHTTPPGLHYHLPYPIEAVILPKVTVENRIELGFRGIGENARGRTPSRDVLEESLMLT
GDENIIDIDFSVIWVIKDAGAFLFNLRDPEGTVNRAAESAMREVIGQTPIQVALTEGRQQIEDRTKELLQAMMDEYNAGI
TIRRVQLLKVDPPAQVVDAFNDVQRSRADRERLRNEAEAYRNSVIPEARGQAEQLLQQAEAYREEIVNRAQGDVARFNSV
LEGYRLNRDVTTQRIYLETMEEVLRNVNKVIIDKNGQGVVPYLPLPEVRARQGGAAAIAPSGLSGAPLRPMSQPIPGLPA
AQGGGR

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=402, Percent_Identity=33.0845771144279, Blast_Score=193, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 44209; Mature: 44078

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGWNQQGGGPWGGGGGGGGGPWGSGGRGGNGRGFGGGSGGQPPDLEEMLRRSQERFRKMV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PGGNLGNKGIGLVAILALAVWLLTGFYRVGTDEQGVVMRFGEFTHTTPPGLHYHLPYPIE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCCE
AVILPKVTVENRIELGFRGIGENARGRTPSRDVLEESLMLTGDENIIDIDFSVIWVIKDA
EEEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEECEEEEEEEECC
GAFLFNLRDPEGTVNRAAESAMREVIGQTPIQVALTEGRQQIEDRTKELLQAMMDEYNAG
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITIRRVQLLKVDPPAQVVDAFNDVQRSRADRERLRNEAEAYRNSVIPEARGQAEQLLQQA
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EAYREEIVNRAQGDVARFNSVLEGYRLNRDVTTQRIYLETMEEVLRNVNKVIIDKNGQGV
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEE
VPYLPLPEVRARQGGAAAIAPSGLSGAPLRPMSQPIPGLPAAQGGGR
ECCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GWNQQGGGPWGGGGGGGGGPWGSGGRGGNGRGFGGGSGGQPPDLEEMLRRSQERFRKMV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PGGNLGNKGIGLVAILALAVWLLTGFYRVGTDEQGVVMRFGEFTHTTPPGLHYHLPYPIE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCEEEECCCCCE
AVILPKVTVENRIELGFRGIGENARGRTPSRDVLEESLMLTGDENIIDIDFSVIWVIKDA
EEEECCCCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEECEEEEEEEECC
GAFLFNLRDPEGTVNRAAESAMREVIGQTPIQVALTEGRQQIEDRTKELLQAMMDEYNAG
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
ITIRRVQLLKVDPPAQVVDAFNDVQRSRADRERLRNEAEAYRNSVIPEARGQAEQLLQQA
EEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
EAYREEIVNRAQGDVARFNSVLEGYRLNRDVTTQRIYLETMEEVLRNVNKVIIDKNGQGV
HHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCEE
VPYLPLPEVRARQGGAAAIAPSGLSGAPLRPMSQPIPGLPAAQGGGR
ECCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]