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The map label for this gene is degP [H]

Identifier: 83593536

GI number: 83593536

Start: 2555293

End: 2556819

Strand: Reverse

Name: degP [H]

Synonym: Rru_A2201

Alternate gene names: 83593536

Gene position: 2556819-2555293 (Counterclockwise)

Preceding gene: 83593537

Following gene: 83593535

Centisome position: 58.74

GC content: 65.23

Gene sequence:

>1527_bases
GTGTTTCAATCCGTGCTTGATCGCACCGCTTCCAACGGAGCCGGGTCCGCGGGCCGCCTGCGCCGCGCCCTGGCGCCGGC
CCTGGTCGCCTTCTCCCTGGCCATCGCGCCGTTCTCCGCCCAGGCCCGCGAGATCCCCGAAAGCTTCGCCGATCTCGCCG
AGGGTTTGTTGCCCGCGGTGGTCAACATCTCCACCACCCAGACCATCGATGCCGATCGTGGTCCGGAAATGCCCCAGTTC
CCGCCGGGGTCGCCCTTCGAGGAGTTCTTCAAGGATTTCTTCGAACGCCATGGCGGGCCGGGCGGCGGCGTCCAGCCCAA
GACCCCGCGCCGGGCGACCTCGCTGGGCTCGGGCTTCATCGTCGACGCCGCGGGCTATATCGTCACCAACAACCACGTCA
TCCAGGATGCCGACGAGATCACGGTGATCTTGCATGACGATACGGCGATCAAGGCCGAGCTGGTCGGCAAGGACGAAAAG
ACCGACGTCGCCCTGCTGCGCATCAAGACCGACAAGCCGCTGACCGCCGTGCCCTGGGGCAATTCGGAAGCCGCCCGGGT
GGGTGATTGGGTGATGGCGATCGGCAATCCCTTCGGCCTCGGCGGCACGGTGACCGCCGGCATCATCAGCGCCAAGACCC
GCGATATCAACGCCGGACCCTATGACAGCTTCATCCAGACCGATGCGGCGATCAATAAGGGCAATTCCGGTGGGCCGCTG
TTCAACATGCATGGCGAGGTGATCGGCATCAATACGGCGATCTTCAGCCCCTCGGGCGGGTCGATCGGCATCGGTTTCTC
GGTGCCCTCCAACCTTGCCCATCAGGTGATCGACGATATCAAGAAGTTCGGCCGTACCCGTCGCGGCTGGATTGGCGTGC
GCATCCAGTCGGTGACCGACGAGATCGCCGAGGGCCTGGGTCTTGAAAAATCCGCCGGCGCCCTGATCGCCGCCGTTACC
CCCGGTGGGCCTGCGGCCGCCGCCGGTCTCAAGGTCGGCGATGTCATCGTGTCGTTCGATGGCCGTCCGGTCCCCGATAT
GCGGACCCTGCCGCGGATCGTCGCCGAAACCGAAATCGGCAAGGACGCCGCCATCGGTGTCTGGCGCGAGGGCAAGCGCC
AGGACCTGAAGATGAAGGTCGGTGAACTGGAGGTGGCCGAGGACGAGGGGTTGCTGAACGAACCCGAAACCAGCGGCGTC
ACCGATTCCCAGGGCGGCACCGCCGTCGCCACCATCGGCCTGACGGTGACCAAGCTCGATGACCGCCTGCGCAGCCAGTT
CGGCTTCGATGCCGCCTCGGAAGGCGTGGTGGTGACCGATGTCACCAATGAAAGCGACGCCCAGGAAAAGGGTCTGGAGC
CCGGGACGCTGATCGTCAAGATCAACCAGACCGAGGTCGCCTCGCCCGAAGACGTGGTCAAGGCGGTGGCCAAGGCCAAG
GACGAGGGACGCAAGACCGTTCTTCTGCTGGTCGAGCTGCGCGGAACCCGGACCTTCATTCCGGTCAAAATGGCCGACAA
GAAGTAG

Upstream 100 bases:

>100_bases
CCGGGAACCCCGTTCTCGATAGCTGTCCGAGCGCCGCCGCCGCTTTAGGGTGATGGCGGCCGCGCCGAAAGGCTCCATGG
GTCAAGAAGGAGTTCAACCC

Downstream 100 bases:

>100_bases
TCTTTCGCCGCCTTTCCCGGAGAACGGGCGCCGGTTCCCCCACCAGGGAGCCGGCGCTTTTTTGTTCCCGTTCGGGCGAT
CGCCTGGGATAAACTGCGGC

Product: peptidase S1C, Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 508; Mature: 508

Protein sequence:

>508_residues
MFQSVLDRTASNGAGSAGRLRRALAPALVAFSLAIAPFSAQAREIPESFADLAEGLLPAVVNISTTQTIDADRGPEMPQF
PPGSPFEEFFKDFFERHGGPGGGVQPKTPRRATSLGSGFIVDAAGYIVTNNHVIQDADEITVILHDDTAIKAELVGKDEK
TDVALLRIKTDKPLTAVPWGNSEAARVGDWVMAIGNPFGLGGTVTAGIISAKTRDINAGPYDSFIQTDAAINKGNSGGPL
FNMHGEVIGINTAIFSPSGGSIGIGFSVPSNLAHQVIDDIKKFGRTRRGWIGVRIQSVTDEIAEGLGLEKSAGALIAAVT
PGGPAAAAGLKVGDVIVSFDGRPVPDMRTLPRIVAETEIGKDAAIGVWREGKRQDLKMKVGELEVAEDEGLLNEPETSGV
TDSQGGTAVATIGLTVTKLDDRLRSQFGFDAASEGVVVTDVTNESDAQEKGLEPGTLIVKINQTEVASPEDVVKAVAKAK
DEGRKTVLLLVELRGTRTFIPVKMADKK

Sequences:

>Translated_508_residues
MFQSVLDRTASNGAGSAGRLRRALAPALVAFSLAIAPFSAQAREIPESFADLAEGLLPAVVNISTTQTIDADRGPEMPQF
PPGSPFEEFFKDFFERHGGPGGGVQPKTPRRATSLGSGFIVDAAGYIVTNNHVIQDADEITVILHDDTAIKAELVGKDEK
TDVALLRIKTDKPLTAVPWGNSEAARVGDWVMAIGNPFGLGGTVTAGIISAKTRDINAGPYDSFIQTDAAINKGNSGGPL
FNMHGEVIGINTAIFSPSGGSIGIGFSVPSNLAHQVIDDIKKFGRTRRGWIGVRIQSVTDEIAEGLGLEKSAGALIAAVT
PGGPAAAAGLKVGDVIVSFDGRPVPDMRTLPRIVAETEIGKDAAIGVWREGKRQDLKMKVGELEVAEDEGLLNEPETSGV
TDSQGGTAVATIGLTVTKLDDRLRSQFGFDAASEGVVVTDVTNESDAQEKGLEPGTLIVKINQTEVASPEDVVKAVAKAK
DEGRKTVLLLVELRGTRTFIPVKMADKK
>Mature_508_residues
MFQSVLDRTASNGAGSAGRLRRALAPALVAFSLAIAPFSAQAREIPESFADLAEGLLPAVVNISTTQTIDADRGPEMPQF
PPGSPFEEFFKDFFERHGGPGGGVQPKTPRRATSLGSGFIVDAAGYIVTNNHVIQDADEITVILHDDTAIKAELVGKDEK
TDVALLRIKTDKPLTAVPWGNSEAARVGDWVMAIGNPFGLGGTVTAGIISAKTRDINAGPYDSFIQTDAAINKGNSGGPL
FNMHGEVIGINTAIFSPSGGSIGIGFSVPSNLAHQVIDDIKKFGRTRRGWIGVRIQSVTDEIAEGLGLEKSAGALIAAVT
PGGPAAAAGLKVGDVIVSFDGRPVPDMRTLPRIVAETEIGKDAAIGVWREGKRQDLKMKVGELEVAEDEGLLNEPETSGV
TDSQGGTAVATIGLTVTKLDDRLRSQFGFDAASEGVVVTDVTNESDAQEKGLEPGTLIVKINQTEVASPEDVVKAVAKAK
DEGRKTVLLLVELRGTRTFIPVKMADKK

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=251, Percent_Identity=40.6374501992032, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI22129776, Length=255, Percent_Identity=36.8627450980392, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI24308541, Length=244, Percent_Identity=35.2459016393443, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI7019477, Length=242, Percent_Identity=38.8429752066116, Blast_Score=136, Evalue=6e-32,
Organism=Escherichia coli, GI1786356, Length=472, Percent_Identity=36.228813559322, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1789629, Length=432, Percent_Identity=36.1111111111111, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1789630, Length=274, Percent_Identity=42.3357664233577, Blast_Score=200, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24646839, Length=261, Percent_Identity=31.4176245210728, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 53353; Mature: 53353

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQSVLDRTASNGAGSAGRLRRALAPALVAFSLAIAPFSAQAREIPESFADLAEGLLPAV
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VNISTTQTIDADRGPEMPQFPPGSPFEEFFKDFFERHGGPGGGVQPKTPRRATSLGSGFI
EECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEE
VDAAGYIVTNNHVIQDADEITVILHDDTAIKAELVGKDEKTDVALLRIKTDKPLTAVPWG
EECCCEEEECCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEEEEECCCCEEEECCC
NSEAARVGDWVMAIGNPFGLGGTVTAGIISAKTRDINAGPYDSFIQTDAAINKGNSGGPL
CCCHHHHCCEEEEECCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCE
FNMHGEVIGINTAIFSPSGGSIGIGFSVPSNLAHQVIDDIKKFGRTRRGWIGVRIQSVTD
EEECCCEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHH
EIAEGLGLEKSAGALIAAVTPGGPAAAAGLKVGDVIVSFDGRPVPDMRTLPRIVAETEIG
HHHHCCCCCCCCCEEEEEECCCCCHHHCCCEECEEEEECCCCCCCCHHHHHHHHHHHCCC
KDAAIGVWREGKRQDLKMKVGELEVAEDEGLLNEPETSGVTDSQGGTAVATIGLTVTKLD
CCCEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHH
DRLRSQFGFDAASEGVVVTDVTNESDAQEKGLEPGTLIVKINQTEVASPEDVVKAVAKAK
HHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
DEGRKTVLLLVELRGTRTFIPVKMADKK
CCCCEEEEEEEEECCCEEEEEEEECCCC
>Mature Secondary Structure
MFQSVLDRTASNGAGSAGRLRRALAPALVAFSLAIAPFSAQAREIPESFADLAEGLLPAV
CCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VNISTTQTIDADRGPEMPQFPPGSPFEEFFKDFFERHGGPGGGVQPKTPRRATSLGSGFI
EECCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCCCEE
VDAAGYIVTNNHVIQDADEITVILHDDTAIKAELVGKDEKTDVALLRIKTDKPLTAVPWG
EECCCEEEECCEEEECCCCEEEEEECCCEEEEEECCCCCCCCEEEEEEECCCCEEEECCC
NSEAARVGDWVMAIGNPFGLGGTVTAGIISAKTRDINAGPYDSFIQTDAAINKGNSGGPL
CCCHHHHCCEEEEECCCCCCCCHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCE
FNMHGEVIGINTAIFSPSGGSIGIGFSVPSNLAHQVIDDIKKFGRTRRGWIGVRIQSVTD
EEECCCEEEEEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHH
EIAEGLGLEKSAGALIAAVTPGGPAAAAGLKVGDVIVSFDGRPVPDMRTLPRIVAETEIG
HHHHCCCCCCCCCEEEEEECCCCCHHHCCCEECEEEEECCCCCCCCHHHHHHHHHHHCCC
KDAAIGVWREGKRQDLKMKVGELEVAEDEGLLNEPETSGVTDSQGGTAVATIGLTVTKLD
CCCEEEECCCCCCCCCEEEECCEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHH
DRLRSQFGFDAASEGVVVTDVTNESDAQEKGLEPGTLIVKINQTEVASPEDVVKAVAKAK
HHHHHHCCCCCCCCCEEEEECCCCCCHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHH
DEGRKTVLLLVELRGTRTFIPVKMADKK
CCCCEEEEEEEEECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]