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The map label for this gene is ftsK [H]

Identifier: 83593431

GI number: 83593431

Start: 2425448

End: 2427628

Strand: Reverse

Name: ftsK [H]

Synonym: Rru_A2096

Alternate gene names: 83593431

Gene position: 2427628-2425448 (Counterclockwise)

Preceding gene: 83593432

Following gene: 83593430

Centisome position: 55.77

GC content: 64.83

Gene sequence:

>2181_bases
ATGAGCGCACAGGTGTTTCAGCCCGGCGTCGATACCGCGCCGATGACTTCGGCCCAGGGAACGAAGGCCGAGGAGTTCAA
TCTGTGGTGCGCCATGAACAACCGGCCCTTCGCCCTGCGCCTGTCGGGCTGGCAGGACGGGTCGCGCGAATGGTGCATCG
AAGCCGATCGCGGCCGGCCGGAAGCCGCCGCCATCTGGGGAACGGGGACCGACGAGGAGGCGGTGGCCACCGCCATCGCC
TATGCCTTCGTCGCCGGGATCGAATGGGCCGAAGCCGAGCGCGCCTTGCAAGACGCCGATGACGAGGCCGAAGAGGGGCG
CGGCGAGCCCGAGGTCGAATGGCTTGACGAGGACGAGTTCGAAGAGCGCACCGATGCCCTGCGCGCCGGCCCGCCGCCGC
TTTCCACCAAGATCGCCGGCAGCCGCGTCGCCGGACAGATCACGGTTCGTCTGCCCGAGCCCGATCGGCCCGACTTCGGC
GTGACCGAGTCCTCTGTGCCCGAAGCCGAGGCGTTGGTCGTAGACGACCTTGAGCCCGCCCCCGAGGAGATCCTTGAGCC
CGCCGTCGCCCAGCCGGTGATCCGCTCGCCGCTGGCCCTGGAGGCCGAACCGCTTCCCGATGCCATCTTGCCGCCCTATC
ACCTGCCCGCCGTCGATCTGCTGGGCGGCGGCGATCCCAAGGACGCCATCGAGGAAGAGAGCAACGAGAACGAACTGGCC
GAACAGGCGGCCAAGCTTGAAACCGTTCTGCGCAATTTCCGGGTGCGCGGCGAGATCATGGAGGTCCGCCCCGGCCCCTG
CGTGACGCTGTTCGAATTGGAACCGGTTCCGGGCACCAAATCCTCGACCATCATCAATCTGGCCGACGATATCGCCCGCT
CGATGAGCGCGGTGACGGCGCGTATCGCCCTGGTTCCCGGCCGCAGCGTCATCGGCATCGAATTGCCCAATGCGGTGCGC
GAAACGGTCTATCTCAAGGAAATCCTCGCCTCGGAAGCCTGGAAGACCTCGAAGGCCAAGCTGCCGATGGCTTTGGGCAA
GAATATCGGCGGCGAGCCGGTGGTGGTCGATCTGGCCCGCATGCCCCACCTGCTGATCGCTGGCACCACCGGTTCGGGCA
AATCGGTGGGCATCAACGCCATGATCTTGTCGCTGCTTTATCATCTGCCGCCCGAGCAGTGCCGGCTGATCATGGTCGAT
CCCAAGATGCTGGAGTTGTCGGTCTACGACGACATCCCCCATCTGCTGACCCCGGTGGTGACCGATCCGCGCAAGGCGGT
GGCGGCGCTGAAGTGGGTCGTGCGCGAGATGGAAAGCCGCTACAAGGCGATGTCTCTGCTCGGCGTGCGCAATCTTGATG
GCTATAACGCCCGCGTCACCGATCTGAACGCCCGGGGCGAACAGGTGACCAGCCGGGTACAGGTTGGCTTCGACAAGGAA
CGCCGCGAGCCGGTGTTCGAAGATCGCATCGTCACCTTGCTGCCGCTGCCCTTCATCGTCGTCGTCGTCGACGAGATGGC
CGATCTGATGCTGGTCGCCGGCAAGGAAATCGAAACCCTGATCCAACGCTTGGCCCAGATGGCCAGGGCGGCGGGCATCC
ATCTGATCATGGCCACCCAGCGGCCTTCGGTCGATGTCATCACCGGCACGATCAAGGCCAATTTCCCGACGCGGATCAGC
TTCCAGGTCACCAGCAAGATCGACAGCCGGACCATTCTCGGGGAATCGGGGGCCGAGCAACTGCTCGGGCAGGGCGATAT
GCTGTTCATGCAGGCCGGCGGCCGGATCAGCCGCGTCCATGGCCCCTTCGTCTCCGATCAGGAGGTCGAGGAGGTCGTGG
CCCATCTGCGCACCCAGGCCCAGCCCGATTACGTCTATTCGGTGACCGAGGAGGACGACGACGAGGAGGCCGACTACCCC
GGCGCCGGCGCCATTGACGAGGCGATCAGCGAAGAAGGCGACGACGGCGATCTCTATAGTCAAGCCCTGGCTGTCATCCT
GCGCGAAGGCAAGGCTTCGGTCAGTTTCATCCAGCGCCACCTGCAAATCGGCTATAACCGCGCCGCCCGTCTGGTCGAAA
GAATGGAAAACGAGGGGGTGATCAGTCCGCCCAACCACGTTGGCAAGCGTGAGATCCTGGTTTCGGCCCGTCAATACTTT
GCCGGTCGCGGCGACGATTAA

Upstream 100 bases:

>100_bases
TCGGCGGCGAGGAACAAATCTGGGAGCGGCTGGTGCTGCCCTTCCTGTCGCGGGACGGAGAGGTCACGAAATTGATGGTC
GCTGCCTACAGGTTATCGTG

Downstream 100 bases:

>100_bases
GCCGCCAGCCTTCCTGCGGCCGCATTCTTACCGTCTTGTCACTTGACGGATCCGCACCCAAAGCCGATGCGTAGAGACCA
ACGAGCATTGACCAAGGGCA

Product: cell divisionFtsK/SpoIIIE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSAQVFQPGVDTAPMTSAQGTKAEEFNLWCAMNNRPFALRLSGWQDGSREWCIEADRGRPEAAAIWGTGTDEEAVATAIA
YAFVAGIEWAEAERALQDADDEAEEGRGEPEVEWLDEDEFEERTDALRAGPPPLSTKIAGSRVAGQITVRLPEPDRPDFG
VTESSVPEAEALVVDDLEPAPEEILEPAVAQPVIRSPLALEAEPLPDAILPPYHLPAVDLLGGGDPKDAIEEESNENELA
EQAAKLETVLRNFRVRGEIMEVRPGPCVTLFELEPVPGTKSSTIINLADDIARSMSAVTARIALVPGRSVIGIELPNAVR
ETVYLKEILASEAWKTSKAKLPMALGKNIGGEPVVVDLARMPHLLIAGTTGSGKSVGINAMILSLLYHLPPEQCRLIMVD
PKMLELSVYDDIPHLLTPVVTDPRKAVAALKWVVREMESRYKAMSLLGVRNLDGYNARVTDLNARGEQVTSRVQVGFDKE
RREPVFEDRIVTLLPLPFIVVVVDEMADLMLVAGKEIETLIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRIS
FQVTSKIDSRTILGESGAEQLLGQGDMLFMQAGGRISRVHGPFVSDQEVEEVVAHLRTQAQPDYVYSVTEEDDDEEADYP
GAGAIDEAISEEGDDGDLYSQALAVILREGKASVSFIQRHLQIGYNRAARLVERMENEGVISPPNHVGKREILVSARQYF
AGRGDD

Sequences:

>Translated_726_residues
MSAQVFQPGVDTAPMTSAQGTKAEEFNLWCAMNNRPFALRLSGWQDGSREWCIEADRGRPEAAAIWGTGTDEEAVATAIA
YAFVAGIEWAEAERALQDADDEAEEGRGEPEVEWLDEDEFEERTDALRAGPPPLSTKIAGSRVAGQITVRLPEPDRPDFG
VTESSVPEAEALVVDDLEPAPEEILEPAVAQPVIRSPLALEAEPLPDAILPPYHLPAVDLLGGGDPKDAIEEESNENELA
EQAAKLETVLRNFRVRGEIMEVRPGPCVTLFELEPVPGTKSSTIINLADDIARSMSAVTARIALVPGRSVIGIELPNAVR
ETVYLKEILASEAWKTSKAKLPMALGKNIGGEPVVVDLARMPHLLIAGTTGSGKSVGINAMILSLLYHLPPEQCRLIMVD
PKMLELSVYDDIPHLLTPVVTDPRKAVAALKWVVREMESRYKAMSLLGVRNLDGYNARVTDLNARGEQVTSRVQVGFDKE
RREPVFEDRIVTLLPLPFIVVVVDEMADLMLVAGKEIETLIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRIS
FQVTSKIDSRTILGESGAEQLLGQGDMLFMQAGGRISRVHGPFVSDQEVEEVVAHLRTQAQPDYVYSVTEEDDDEEADYP
GAGAIDEAISEEGDDGDLYSQALAVILREGKASVSFIQRHLQIGYNRAARLVERMENEGVISPPNHVGKREILVSARQYF
AGRGDD
>Mature_725_residues
SAQVFQPGVDTAPMTSAQGTKAEEFNLWCAMNNRPFALRLSGWQDGSREWCIEADRGRPEAAAIWGTGTDEEAVATAIAY
AFVAGIEWAEAERALQDADDEAEEGRGEPEVEWLDEDEFEERTDALRAGPPPLSTKIAGSRVAGQITVRLPEPDRPDFGV
TESSVPEAEALVVDDLEPAPEEILEPAVAQPVIRSPLALEAEPLPDAILPPYHLPAVDLLGGGDPKDAIEEESNENELAE
QAAKLETVLRNFRVRGEIMEVRPGPCVTLFELEPVPGTKSSTIINLADDIARSMSAVTARIALVPGRSVIGIELPNAVRE
TVYLKEILASEAWKTSKAKLPMALGKNIGGEPVVVDLARMPHLLIAGTTGSGKSVGINAMILSLLYHLPPEQCRLIMVDP
KMLELSVYDDIPHLLTPVVTDPRKAVAALKWVVREMESRYKAMSLLGVRNLDGYNARVTDLNARGEQVTSRVQVGFDKER
REPVFEDRIVTLLPLPFIVVVVDEMADLMLVAGKEIETLIQRLAQMARAAGIHLIMATQRPSVDVITGTIKANFPTRISF
QVTSKIDSRTILGESGAEQLLGQGDMLFMQAGGRISRVHGPFVSDQEVEEVVAHLRTQAQPDYVYSVTEEDDDEEADYPG
AGAIDEAISEEGDDGDLYSQALAVILREGKASVSFIQRHLQIGYNRAARLVERMENEGVISPPNHVGKREILVSARQYFA
GRGDD

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=506, Percent_Identity=50.5928853754941, Blast_Score=475, Evalue=1e-135,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 79205; Mature: 79073

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQVFQPGVDTAPMTSAQGTKAEEFNLWCAMNNRPFALRLSGWQDGSREWCIEADRGRP
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEECCCCCC
EAAAIWGTGTDEEAVATAIAYAFVAGIEWAEAERALQDADDEAEEGRGEPEVEWLDEDEF
CEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCEEECCCHHH
EERTDALRAGPPPLSTKIAGSRVAGQITVRLPEPDRPDFGVTESSVPEAEALVVDDLEPA
HHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCC
PEEILEPAVAQPVIRSPLALEAEPLPDAILPPYHLPAVDLLGGGDPKDAIEEESNENELA
CHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHH
EQAAKLETVLRNFRVRGEIMEVRPGPCVTLFELEPVPGTKSSTIINLADDIARSMSAVTA
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHH
RIALVPGRSVIGIELPNAVRETVYLKEILASEAWKTSKAKLPMALGKNIGGEPVVVDLAR
EEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEEHHH
MPHLLIAGTTGSGKSVGINAMILSLLYHLPPEQCRLIMVDPKMLELSVYDDIPHLLTPVV
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHCEEEEECCCEEEEEEHHCCHHHHHCCC
TDPRKAVAALKWVVREMESRYKAMSLLGVRNLDGYNARVTDLNARGEQVTSRVQVGFDKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCHH
RREPVFEDRIVTLLPLPFIVVVVDEMADLMLVAGKEIETLIQRLAQMARAAGIHLIMATQ
HCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECC
RPSVDVITGTIKANFPTRISFQVTSKIDSRTILGESGAEQLLGQGDMLFMQAGGRISRVH
CCCCEEEEEEEEECCCCEEEEEEECCCCCCEEECCCCHHHHHCCCCEEEEECCCCEEEEC
GPFVSDQEVEEVVAHLRTQAQPDYVYSVTEEDDDEEADYPGAGAIDEAISEEGDDGDLYS
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHH
QALAVILREGKASVSFIQRHLQIGYNRAARLVERMENEGVISPPNHVGKREILVSARQYF
HHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
AGRGDD
CCCCCC
>Mature Secondary Structure 
SAQVFQPGVDTAPMTSAQGTKAEEFNLWCAMNNRPFALRLSGWQDGSREWCIEADRGRP
CCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCEEEEECCCCCCCCCEEEECCCCCC
EAAAIWGTGTDEEAVATAIAYAFVAGIEWAEAERALQDADDEAEEGRGEPEVEWLDEDEF
CEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHCCCCCCEEECCCHHH
EERTDALRAGPPPLSTKIAGSRVAGQITVRLPEPDRPDFGVTESSVPEAEALVVDDLEPA
HHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCC
PEEILEPAVAQPVIRSPLALEAEPLPDAILPPYHLPAVDLLGGGDPKDAIEEESNENELA
CHHHHCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCHHHHH
EQAAKLETVLRNFRVRGEIMEVRPGPCVTLFELEPVPGTKSSTIINLADDIARSMSAVTA
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHH
RIALVPGRSVIGIELPNAVRETVYLKEILASEAWKTSKAKLPMALGKNIGGEPVVVDLAR
EEEEECCCEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCEEEEHHH
MPHLLIAGTTGSGKSVGINAMILSLLYHLPPEQCRLIMVDPKMLELSVYDDIPHLLTPVV
CCEEEEEECCCCCCCCCHHHHHHHHHHHCCHHHCEEEEECCCEEEEEEHHCCHHHHHCCC
TDPRKAVAALKWVVREMESRYKAMSLLGVRNLDGYNARVTDLNARGEQVTSRVQVGFDKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHCCCCHH
RREPVFEDRIVTLLPLPFIVVVVDEMADLMLVAGKEIETLIQRLAQMARAAGIHLIMATQ
HCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEECC
RPSVDVITGTIKANFPTRISFQVTSKIDSRTILGESGAEQLLGQGDMLFMQAGGRISRVH
CCCCEEEEEEEEECCCCEEEEEEECCCCCCEEECCCCHHHHHCCCCEEEEECCCCEEEEC
GPFVSDQEVEEVVAHLRTQAQPDYVYSVTEEDDDEEADYPGAGAIDEAISEEGDDGDLYS
CCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHH
QALAVILREGKASVSFIQRHLQIGYNRAARLVERMENEGVISPPNHVGKREILVSARQYF
HHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
AGRGDD
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]